Hydrocortisone in ampoules. Price, instructions for use, what it is used for, where to buy for compresses, analogues, reviews

Hydrocortisone - medicinal solution in ampoules, which has several medicinal properties and has a fairly wide range of applications in various fields of medicine.

The price of the product is affordable, so it can be used by patients with different incomes when such a need arises. It should be borne in mind that the remedy is hormonal, so it is important to follow all the rules and consult with a doctor first, which will avoid complications.

Forms of release and composition

The medicine is available to patients in several dosage forms. One of the most popular forms is considered to be a solution used for intramuscular, intravenous administration, and other uses.

The liquid is transparent, has a white or almost white color, as well as a specific drug smell. It is packaged in 1 ml clear glass ampoules. Ampoules are placed in cardboard boxes of 5 or 10 pieces, depending on the manufacturer.

In addition, each box contains instructions for use. There is also a remedy in the form of an eye ointment, an ointment for external use with different concentrations of the active ingredient. On pharmacy shelves, you can also find a cream for external application on the skin, which differs from the ointment in its consistency and concentration of the active substance.

Each dosage form contains the substance hydrocortisone, which acts as the main active ingredient. 1 ml of solution contains 25 mg of this component. The auxiliary substance in the composition is lidocaine, the amount of which per 1 ml is 5 mg. There are no other ingredients in the medicine.

In other forms of release, there are auxiliary ingredients that do not have medicinal properties. The medication is produced by various pharmaceutical companies in Russia and Ukraine.

Pharmacological properties

Hydrocortisone in ampoules (the price may depend on the amount of the product in the package) and other dosage forms has pronounced anti-inflammatory and antihistamine properties.

The anti-inflammatory effect is achieved due to the content of hydrocortisone. This component helps suppress the inflammatory process and stimulates tissue repair, as well as prevents the multiplication of microorganisms, which is considered a good prevention of complications.

Thanks to the action of the agent, the severity of allergic manifestations is weakened. The substance acts on blood vessels, reduces the permeability of their walls, and helps prevent edema. Additionally, the ingredient has a positive effect on tissues, which improves the patient's condition.

It is worth noting that the antihistamine effect is manifested not only on the skin, but also on internal organs, for example, from the bronchi in patients with severe bronchial asthma.

Another property of the drug is the ability to influence metabolic processes in the body, which accelerates recovery and prevents various complications during a long course of inflammatory, infectious process.

Pharmacodynamics and pharmacokinetics

After the introduction of the drug, a fairly rapid distribution of the component in the body and the provision of a therapeutic effect occurs. Hydrocortisone belongs to the hormones of the adrenal cortex and has a similar effect to cortisone, but it is considered stronger, has pronounced properties.

The substance has a positive effect on the metabolism of proteins, fats and carbohydrates in the body. Additionally, the substance increases the level of glucose in the blood, while simultaneously stimulating the production of insulin, activating the work of the pancreas. In addition, the component affects the level of sodium in the blood, and also retains water in the body.

It should be noted that hydrocortisone enhances the excretion of calcium from the body. This can negatively affect the patient's condition with prolonged use of the medicinal solution. The drug has immunosuppressive properties, which suppresses the activity of microorganisms and the process of cell division in various inflammatory processes.

When using the drug for the treatment of joints, an improvement in the condition of the connective tissue of the synovial bag is noted, which has a positive effect on the course of the pathological process.

A pronounced anti-shock effect of the agent is noted when used during an exacerbation of a disease or the development of a vascular crisis. As a result, there is an activation of the heart, an increase in blood pressure indicators and their maintenance at a normal level.

This prevents the recurrence of symptoms. The complex effect of the drug helps to cope with the acute manifestations of various diseases, as well as prevent severe complications against the background of the low effectiveness of other drugs.

After intravenous administration or the use of the drug in other ways, the active component is rapidly distributed through the systemic circulation. The maximum concentration in the blood is detected after 15-20 minutes, which ensures fast response and high efficiency.

The drug is well absorbed in the body, but its bioavailability does not exceed 60%, which does not impair its effectiveness.

It is worth noting that the main substance of the composition penetrates through the cell membranes, the placental barrier, and enters breast milk.

The concentration of the substance in the placenta is approximately 70%, which is a high indicator. When the drug is administered intramuscularly, the components are slowly absorbed. The withdrawal period in each case depends on the dosage, the patient's age and accompanying deviations from the internal organs. Its average duration is 12-24 hours.

The active ingredient is processed in the liver, therefore, when this organ is damaged, the metabolism slows down. In patients who suffer from mild kidney disease, the period of elimination of the components is somewhat slowed down, which does not affect the effectiveness and speed of obtaining a therapeutic result.

Indications for use

Hydrocortisone is often prescribed to patients with various pathological conditions at different stages. The tool in ampoules is very popular, as it has a low price and can be used in various ways.

The main indications for the appointment of the solution:

• Arterial hypotension of varying severity, when the indicators are constantly decreasing.
• Shock of cardiogenic or traumatic origin, in which there is a violation of consciousness and a threat to the patient's life.
• Severe bronchial asthma with regular attacks. In this case, the patient is prescribed a remedy not only as first aid, but also for course use.
• Hepatic coma, severe course of thyroid pathologies.
• Addison's disease, in which collapse is possible.
• Serum sickness with the introduction of any serum, vaccines with a therapeutic purpose.
• Exacerbation of chronic diseases of the digestive tract. With minor erosive changes, the agent can be prescribed in short courses in order to improve the condition.
• Pathologies of an allergic origin, for example, conjunctivitis, dermatitis, skin lesions with hay fever, the development of Quincke's edema upon contact with allergens in the form of food, medicines.
• Joint pathologies of rheumatic and inflammatory origin. The remedy is effective for arthritis of various forms, bursitis, rheumatoid arthritis, synovitis and tendosynovitis, post-traumatic and gouty forms of arthritis.
• Systemic lupus erythematosus at different stages of development.

The medicine can be used for dermatitis, eczema, psoriasis. It is often prescribed for seborrhea of ​​various origins, as well as during exacerbation of various disorders of the auditory and visual apparatus.

Contraindications

The drug has a very pronounced effect on the body, therefore its use is not recommended for intolerance components of the composition, as well as during pregnancy and breastfeeding, which is associated with an increased risk of developing complications.

Do not prescribe a remedy for an uncontrolled form of arterial hypertension, as well as in the case of diagnosing epilepsy, nephropathy.

Contraindications include diabetes mellitus, as well as Itsenko-Cushing's disease, progressive osteoporosis, which in most cases is diagnosed in women during menopause.

Do not prescribe a solution when detecting an active form of pulmonary tuberculosis, systemic fungal pathologies or renal failure of a severe form with severe impairment of the functioning of the paired organ.

In addition, the drug is not used for 1-2 weeks after vaccination, as well as for the treatment of patients with AIDS. The latter contraindication is explained by immunosuppressive properties, which aggravate the course of immunodeficiency states.

At what age can the drug be used?

Hydrocortisone in ampoules (the price may vary in different regions) is prescribed for patients over 1 year old. Application for newborns should be coordinated with a specialist. Pediatricians prescribe medication in exceptional cases.

Instructions for use, dosage

For various diseases, the treatment regimen with hormonal medication may differ. However, there is a standard method of application suitable for the treatment of many disorders.

Intramuscularly, children are injected no more than 0.5 ml of the drug 2 times a day for 3-5 days. Longer term use is not recommended. Adults are prescribed from 2 to 4 ml per day, depending on the severity of symptoms. Course duration - up to 7 days

The solution is also injected into the joint cavity, 1 ml once every 7-10 days. You can repeat the introduction no more than 3 times in a row. For children over 14, the agent is rarely injected into the joint cavity, only for strict indications.

As a rule, intra-articular administration is prescribed for severe inflammation and the lack of effect from the use of other medications.

For compresses

Usually compresses are prescribed for inflammatory lesions of the joints of various origins in adults and children from 14 years of age. The treatment regimen involves the use of the medication for 10 days.

For 1 ml of solution, you should take 15 ml of 0.9% sodium chloride and 5 ml of medical alcohol. All components are mixed, after which they are poured from a syringe onto a small piece of gauze or cloth, applied to the sore joint for 1 hour.

During the manipulation, a burning sensation may appear, minor discomfort, which usually disappears after a while. This method is not considered a classic, so you should first consult with a specialist in order to prevent complications.

For electrophoresis

For joint pain and some other systemic diseases, for example, the spine, internal organs, electrophoresis is used. The procedure involves exposure to the affected areas with special low frequency electrical waves, which leads to the activation of the healing process.

With medicinal electrophoresis, pieces of gauze or tissue soaked in a medicinal solution, such as Hydrocortisone, are placed under special pads. As a result, efficiency is increased. The procedures are carried out once every 3 days for 3 weeks. The duration of the manipulation is 20 minutes.

For inhalation

Many patients consider inhalations with the remedy to be very effective in bronchial asthma and obstructive pathologies of the respiratory system. The procedures are carried out using a nebulizer, into which 1 ml of solution and 4 ml of sodium chloride 0.9% are poured. For 5 minutes, the patient inhales vapors of the agent.

When treating children, the dosage of Hydrocortisone can be reduced to 0.5 ml. The manipulation should be carried out every day for a week.

For ear treatment

In case of inflammatory diseases of the ears, it is recommended to instill 1 drop of the medicinal solution into each ear for 3-5 days. Longer use is not recommended as the risk of complications increases.

This method is rarely used, since there are many medicines that also contain hormonal substances and are designed specifically for the treatment of pathologies of the hearing aid.

Into the nose

With rhinitis of various origins, the use of the drug is considered inappropriate, since there is no data on its effectiveness. Despite this, some patients use a solution for instilling 1-2 drops into each nasal passage.

Before instillation, 1 ml of the solution is mixed with 1 ml of sodium chloride 0.9%. The maximum duration of treatment is 5 days.

Side effects

Hydrocortisone in ampoules (the price may differ depending on the manufacturer) often provokes negative reactions, especially if the instructions for its use are violated.

Organs and systems	The most common manifestations
Nervous system	Headache is common. Patients may be disturbed by insomnia, mental impairment, manifested in the form of aggression or other abnormalities.
Vessels and heart	When treating patients, tachycardia and arrhythmia may disturb, a critical increase in blood pressure and the accompanying complications of this disorder are often noted.
Respiratory system	Spasm of the bronchi and lungs, shortness of breath during exercise and at rest, pain in the bronchi. A severe cough is sometimes observed.
Digestive tract	Pain in the stomach, indigestion and lack of appetite during therapy are noted in many patients. Sometimes there is diarrhea, pain in the bowel area, and bloating.
Genitourinary system	Menstrual irregularities, decreased or increased libido are observed in women, especially during menopause. Sometimes there is a lack of normal urination, which is associated with water retention in the body.
Musculoskeletal system	The most common complications are osteoporosis and joint and muscle pain.
Leather	An allergy to a medication manifests itself only in case of intolerance to its components, manifests itself in the form of a rash, burning sensation, itching and peeling of the skin.

The appearance of adverse reactions should be the reason for discontinuation of the medication.

Overdose

With the introduction of large doses of the drug intravenously or intramuscularly, patients experience an overdose, accompanied by nausea, vomiting and internal bleeding.

In addition, there is a severe headache associated with a critical increase in blood pressure and the development of a hypertensive crisis. If such symptoms appear, you should immediately stop using the product and visit a doctor.

In a hospital setting, the patient is assisted, symptomatic treatment is prescribed in order to eliminate violations.

special instructions

Hydrocortisone in ampoules (the price of the medicine is available in different regions) is rarely prescribed for external use. However, the advantage of such use is the minimal risk of overdose.

If the product is used for compresses, it is important not to apply a gauze bandage to the area where there is damage to the skin. In addition, when used for the purpose of inhalation, it is important to obtain a doctor's approval, since the agent can provoke complications.

The use of ear and nose therapy also brings dubious benefits, more often patients experiment on their own, which leads to disastrous results. That is why you should not use the medicinal solution for other purposes.

The only way that really pays off is the application during electrophoresis. Such procedures significantly shorten the recovery period and improve the condition of the joints and internal organs.

Drug interactions

The medication is not used in combination with other corticosteroids, as there is a risk of complications. You should not combine the drug with antiviral, barbiturates and antiallergic drugs, since there is a significant weakening of its effectiveness.

Do not prescribe Hydrocortisone in combination with diuretics, antiepileptic and non-steroidal anti-inflammatory drugs. It is strictly contraindicated to inject the solution 3 days before and 10-14 days after vaccination.

Analogs

In some cases, the use of the original medicine is not possible, so experts prescribe substitutes with similar properties.

The most effective analogues:

• Prednisolone - a solution based on the active ingredient of the same name, which also has pronounced properties and belongs to the hormones of the adrenal cortex. Helps relieve inflammation and has antihistamine properties. It is prescribed for adults and children with a variety of diseases, and is often used as a first aid.
• Dexamethasone - a synthetic analogue of the drug based on the active substance of the same name. It is produced in the form of a solution, it is prescribed for adults and children. The drug also has anti-inflammatory and antihistamine effects, despite its different composition.

Analogs of the remedy also have a strong effect, therefore, independent use is strongly discouraged.

Terms, conditions of sale and storage

You can buy the solution at the pharmacy only with a doctor's prescription. The maximum storage time is 5 years. During storage, it is important to avoid freezing, limit access to children and direct sunlight.

Price

The cost of the medicine is approximately 200-250 ml. It may differ depending on the manufacturer and region of distribution.

Hydrocortisone is an effective drug in the form of a solution in ampoules, which has anti-inflammatory and anti-allergic properties. The price of the tool is quite affordable, which allows it to be used in long courses.

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