Levodopa / Benserazide-Teva. Price, instructions for use, reviews

Levodopa / Benserazide-Teva is an effective antiparkinsonian medication that is often used for therapy of patients with various forms of the disease and other lesions of the nervous system. The price of the medicine is high in different pharmacies and regions. This is considered the main reason why patients cannot take the drug. The cost of the drug is justified by its high efficiency, so it is often prescribed.

Selling features

To date, the dispensing of a drug from pharmacies is carried out after the presentation of a prescription form from doctor, which somewhat reduces the likelihood of developing severe complications against the background of independent uncontrolled admission.

The cost of the medication ranges from 500-1200 rubles. depending on the amount in the package.

Composition, release form

Levodopa / Benserazid-Teva (the price of the medication depends on the specific pharmacy) is available for patients in the form of tablets for oral use. They are small in size and round in shape, pink in color.

The medicine is packaged in small bottles, each of which contains 20, 30, 50, 60 or 100 tablets. Vials are always placed in small cardboard boxes of 1 piece. In the box you can find a scripture, which indicates the nuances of use and possible contraindications for treatment.

The composition of the product includes 2 active ingredients - levodopa and benserazide. They have a major therapeutic effect. Moreover, each tablet can contain 100 or 200 mg of levodopa, 25 or 50 mg of benserazide.

Present in the composition and auxiliary ingredients:

• Silica.
• Talc.
• Starch.
• Dye.
• Mannitol.
• Microcrystalline cellulose.

These substances have no medicinal properties.

Operating principle

The medication is considered effective if used correctly after a preliminary examination. Its principle of action is based on the ability of active ingredients to block the symptoms of Parkinson's disease and some other disorders.

The drug also stimulates the production of dopamine in the body, as with a lack of this ingredient, the disease progresses rapidly. Most of the levodopa, when ingested, is transformed into dopamine, which helps to improve the condition of patients.

But such an effect is achieved only when two components are combined in the composition of the product. This is due to the fact that most of the dopamine formed is not able to prevent the development of Parkinson's disease. But the combination of ingredients enhances the therapeutic effect.

Another effect of the drug is noted:

• When benserazide is combined with levodopa, a better penetration of the latter component into the blood is observed, which helps to achieve a pronounced antiparkinsonian effect.
• The undesirable reactions that are often observed with the disease disappear. This helps to avoid the development of complications and slow down the progression of the pathological condition.
• The medication reduces the frequency of attacks in severe cases. This effect is especially pronounced in patients suffering from a chronic form of pathology.
• Improves the functioning of the central nervous system, prevents the appearance of cognitive disorders in patients, which can not only worsen the general condition, but also provoke concomitant deviations from the internal organs.

The drug is well tolerated by patients, despite the fact that it acts aggressively on the body. Its absorption after consumption is carried out through the walls of the small intestine, the components of the composition spread through the systemic circulation and have a therapeutic effect.

Levodopa / Benserazide-Teva (the price of the medicine is higher when purchasing a large package) for a certain period of time is retained in the patient's body. That is why the likelihood of developing an overdose increases if used incorrectly. The effectiveness of the drug depends on the dosage, the effect increases with its increase.

The maximum concentration of ingredients in the blood is observed 1 hour after taking a single therapeutic dosage. During the day, the level of ingredients can be maintained, after which it gradually decreases. During the day, the concentration gradually decreases. The processing of ingredients is carried out in the liver, after which they are evacuated mainly by the kidneys.

If the functioning of the paired organ is impaired, there is a deterioration in the excretion of decay products of active ingredients. This often provokes complications as a result of the accumulation of substances in the blood. Pharmacokinetic characteristics may differ from patient to patient.

Indications and contraindications for use

The drug is used for neurological disorders of varying severity.

The main indications for the appointment of a tablet preparation:

• Parkinson's disease at different stages of development. The drug is used in the acute and chronic course of the disorder, even in the event of complications in patients.
• Diagnosing restless legs syndrome, which often develops with neurological disorders or kidney damage, requiring the patient to undergo hemodialysis.
• The development of parkinsonism syndrome in patients not only as a result of psychotic disorders, but also against the background of other disorders.

The medicine is often included in the course of the main treatment for some other diseases of neurological origin. In each case, the doctor individually decides on the prescription of the medication.

Levodopa / Benserazide-Teva is not used when detecting intolerance to the components of the composition. The high price is an obstacle for many, but does not apply to contraindications.

The medicine has many more contraindications, since it has aggressive properties:

• Closed-angle glaucoma, accompanied by severe disorders of the visual apparatus.
• The period of gestation and breastfeeding.
• Acute mental illness with psychotic disorders. With such violations, the use can provoke an aggravation of symptoms.
• A severe course of allergies that develop as a result of the use of other medicines.
• The patient's age is up to 25 years. This contraindication is considered one of the most unusual, since many drugs are allowed to be used for patients over 18 years of age.
• Internal bleeding in acute and chronic form, developing as a result of perforation of the wall of the digestive tract.
• Acute peptic ulcer and gastritis with increased acidity of gastric juice.
• Endocrine system pathologies in acute form.
• Severe course of diseases of the cardiovascular system.
• Liver failure.
• Acute kidney disease. An exception is a violation on the part of the paired organ, in which the patient receives dialysis.

  

If the patient is of reproductive age, but does not use reliable methods of contraception, the drug is not prescribed. This is associated with an increased risk of fetal development disorders when using even small doses of the drug.

During therapy, patients may develop severe complications from the internal organs. Most often, patients talk about indigestion, nausea and vomiting. Many people note the disappearance of gustatory sensations, even when eating food with a bright taste and aroma. Decreased appetite or a complete lack of it leads to anorexia, metabolic disorders and severe weakness.

Negative reactions are manifested in the form of arrhythmias, leukopenia, drowsiness. With prolonged use, all negative reactions are aggravated, an overdose may develop. In this case, the condition worsens greatly, the development of Quincke's edema or acute urticaria is often noted. Such violations can not only threaten the health of the patient, but also lead to death in the absence of timely assistance.

It is impossible to ignore the manifestations, as well as to use any medications without a doctor's prescription. This can make the symptoms worse.

Instructions for use

Levodopa / Benserazide-Teva (the price of the medication is fully justified by its high efficiency) is used only after a preliminary diagnostic examination and identification of the stage of development of the pathological states. There is a standard treatment regimen, but it can vary depending on the characteristics of the patient's body.

Features of the disease	The scheme of using the medication
Mild form of pathology	With a mild course of the disorder, the agent is taken in an average dose, which is 400 mg of levodopa and 100 mg of benserazide. The daily rate must be divided several times during the day, which allows for a uniform effect on the body. The duration of use in each case is determined individually. It is allowed to take pills before meals or 2 hours after them, since taking them immediately after eating leads to a slowdown in the onset of the therapeutic effect. When a therapeutic result appears, the doctor assesses the patient's condition, decides to extend the course or cancel the drug.
The neglected course of the disease	In a severe course of the disorder, the agent is used in increased doses, since it is necessary to quickly eliminate the symptoms of the disease. Typically, patients are prescribed a dosage of 800 mg levodopa and 200 mg benserazide. It must be divided into 4 times and taken at approximately equal time intervals throughout the day. When negative reactions appear, the doctor does not always immediately cancel the treatment. In some cases, he only reduces the dosage and monitors the patient's condition. If there is no therapeutic effect, and the negative reactions worsen, the treatment is canceled. Sometimes the prescription of drugs is required to normalize the condition.
The appearance of symptoms of the disease in patients who have not previously taken the medication	If the patient has never taken medications based on such components, the initial dosage is 50 mg of levodopa and 12.5 mg of benserazide. In the absence of negative reactions and the onset of the initial therapeutic effect, an increase in the dose is possible. In each case, the rate is determined depending on the patient's condition. The patient alone cannot increase the dosage or prolong the course.

The therapeutic course when using the drug can last several days or several weeks, depending on the manifestations of the disease. During the period of therapy, the patient regularly visits a doctor who assesses the condition and, if necessary, adjusts the dosage.

In the first few days, the patient's condition may worsen, but this does not always require discontinuation of the medication. Often the symptoms disappear on their own after a few days, and a therapeutic effect also occurs.

The pill should be taken at regular intervals. It is strictly forbidden to take the entire daily dose of the medication at a time. This can lead to serious complications.

Some analogues, prices

Levodopa / Benserazide-Teva, the price of which is high, has analogues that are used when it is impossible to prescribe it. Substitutes have a similar composition, sometimes they contain other components in the composition.

The most effective analogues:

• Madopar has the same composition, therefore it can be used for the therapy of patients if it is impossible to prescribe the original. The medicine is available in the form of capsules and tablets for oral administration, which have different doses of active ingredients. The drug is prescribed for various forms of Parkinson's disease, as well as the presence of complications in patients against the background of such a violation. It is taken orally in the dose prescribed by the doctor, depending on the state of neglect. One of the disadvantages of the drug is its high price, which starts from 1200 rubles. and can reach 2000 rubles.
• Sindopa is considered an affordable and effective analogue, which costs about 140-200 rubles. It contains levodopa, as well as carbidopa. The medicine is available in tablet form and helps to eliminate many neurological disorders in patients with Parkinson's disease. With the use of the drug, there is a rapid improvement in the condition, and the risk of complications due to the use of the drug is also reduced. The remedy rarely provokes complications, but is used only after examination and identification of the cause of the violation.
• Tremonorm costs about 700 rubles. and is often prescribed to patients when diagnosed with Parkinson's disease at different stages of development. The drug also contains levodopa, as well as carbidopa. The drug has pronounced anti-Parkinsonian properties, not only eliminates the manifestations of the disease, but also stops its progression. When using, complications may develop, so the agent is used only as directed and with caution. Independent use and dosage adjustment is prohibited.
• On whom also contains carbidopa or levodopa, therefore it has pronounced antiparkinsonian properties. The drug is expensive, its price starts at 1350 rubles. Despite this, it is often used due to its high efficiency and mild effect on the body. When prescribed in minimal dosages, the drug rarely provokes complications, but this is not considered a reason for uncontrolled use without a doctor's prescription. The medicine is not considered more effective than the original, but in some cases it brings more pronounced results.

The use of any analogue requires prior consultation with a doctor. it is strictly forbidden to select a substitute on your own, as this can provoke complications, even if there are the same ingredients in the composition.

Terms and conditions of storage

The duration of storage of the drug is 2 years. In this case, it is important to prevent moisture and direct sunlight from getting on it.

It is necessary to protect the drug from children. Application after the expiration date is strictly prohibited. The information on the package must be read before starting treatment.

Levodopa / Benserazide-Teva is a popular and effective treatment for Parkinson's disease of varying degrees of severity. The high price of the drug is considered the only drawback, since it is very effective and brings results quickly. When applying, it is important to pre-pass a diagnostic examination, which will reduce the likelihood of complications during therapy.

Video about the drug Levodopa

Side effects of Levodopa: