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Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology, intensive care

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Content

  1. What is a polarizing mixture
  2. Dropper composition
  3. The principle of action on the body
  4. Indications for use
  5. Contraindications for use
  6. Method of administration and dosage
  7. Video about cardiotonic drugs

Replenish broken volumes potassium in the body for heart problems, the polarizing mixture allows. Droppers with it are prescribed to their patients by cardiologists. The composition of the product from 4 components affects the heart muscle and protects it from heart attacks.

Polarizing drug:

  • has a changing composition;
  • regenerates electrolyte balance in the myocardium;
  • reduces the area of ​​necrosis during a heart attack;
  • stabilizes the rhythm of contractions;
  • weakens the action of ischemia.

What is a polarizing mixture

A fast-acting drip drug, a polarizing mixture, is used for the treatment of complex heart diseases. The tool is made in pharmacies of therapeutic departments according to the presented medical prescriptions. The basis of the drug is 5- or 10% glucose. When creating a solution for a dropper, it is combined with other components.

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Additions to glucose in the polarizing mixture can be:

  • panangin;
  • asparkam;
  • potassium chloride.

The polarizing agent is administered through the system, intravenously. Such a mixture can include various components. Its composition depends on the individual characteristics of the organism. Droppers with a similar drug are most popular in cardiology.

Insulin with a short action is designed to level the strong glucose load in the product. Its amount determines the content and concentration of sugar in the preparation. Additionally, but not necessarily, magnesium may also be present in the polarizing mixture.

Insulin allows all components to penetrate into the cell space. Glucose maintains cell energy. Magnesium strengthens the nervous system, and potassium easily generates acting potential.

Dropper composition

The following table shows that there are several approximate formulations for creating polarizing solutions:Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology

Number and approximate name of the composition Potassium chloride content (g) Insulin content (units) Glucose content (ml)
Classical 2 6 350%)
Concentrated 4 8 2500%)
Component replacement Panangin (magnesium sulfate) - 80 ml 8 150 (10%)

The polarizing composition of the droppers contributes to the saturation of electrolytes that the body loses under certain circumstances.

Potassium deficiency, for example, is caused by:

  • coma with diabetes mellitus;
  • postoperative periods;
  • long-term use of corticosteroids or diuretics;
  • significant electrolyte loss with diarrhea or vomiting;
  • renal lesions;
  • cirrhosis of the liver.

Hypokalemia manifests itself clinically:

  • intestinal paresis;
  • nausea;
  • vomiting;
  • muscle weakness;
  • depression;
  • cardiovascular disorders.

Macronutrient potassium in the body:

  • maintains homeostasis;
  • stimulates biological cellular activity;
  • regulates neuromuscular conduction and excitability.Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology

The polarizing mixture (the composition of the dropper controls the number of sodium and calcium in the cells) helps to weaken the excitability of the myocardium. This magnesium preparation lowers blood pressure and inhibits the circulation of abnormal impulses in arrhythmias. With all this, internal metabolic processes also improve.

The properties of magnesium are attributed to:

  • regulation of physiological and biochemical reactions;
  • beneficial effect on the central nervous system and myocardial cells;
  • participation in the regulation of electrolyte balance within cells;
  • stabilization of vascular tone;
  • prevention of electrical cellular instability;
  • inhibition of blood clots;
  • decrease in pressure;
  • weakening of arterial spasms;
  • muscle relaxation;
  • increased urination.

The causes of magnesium deficiency include:

  • treatment with diuretics;
  • diarrhea or vomiting;
  • ulcerative colitis;
  • starvation;
  • alcoholism;
  • stress;
  • endocrine disorders;
  • pregnancy.

With hypomagnesemia, the following are observed:

  • obstetric complications;
  • convulsions;
  • depression or anxiety;
  • dizziness;
  • vomit;
  • diarrhea;
  • nausea;
  • adverse manifestations of the heart and blood vessels;
  • bronchospasm.

The principle of action on the body

Components of a complex therapeutic mixture:

  • help substances to enter cells unhindered (insulin)
  • support the energy of molecules (glucose);
  • strengthen the nervous system (magnesium);
  • facilitate the generation of effective potential (potassium).Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology

Polarizing droppers have long been recognized by doctors. Complex formulations have earned confidence in themselves due to their positive effects on heart attacks. Such mixtures normalize the heart rate by stabilizing the disturbed metabolism. Together with this, the volumes of potassium lost during illness are replenished.

Panangin or magnesium sulfate solution, if included in a polarizing mixture, maintains the cardioprotective effect of the agent.

He also has such characteristics as:

  • prevention of blood clots;
  • decrease in pressure;
  • weakening of arterial spasms;
  • relaxation of muscles;
  • increased urination.

The polarizing mixture (the composition of the dropper has a regenerating and protective effect) is indicated for serious heart problems. Doctors also prescribe this remedy for those who have a deficiency of magnesium and potassium in their blood. The drug stabilizes the rhythm and has a beneficial effect on the heart.

With the accumulation of potassium inside the body under the influence of glucose and insulin, muscle cells become more polar, and also respond more easily to excitatory signals.

In case of an overdose of potassium, which occurs after the rapid introduction of a polarizing mixture through the system, side effects such as:

  • allergy;
  • acidosis;
  • hyperkalemia;
  • paralysis;
  • fatigue;
  • muscle weakness;
  • paresthesia and convulsions;
  • heaviness in the arms or legs;
  • confusion of consciousness;
  • heart failure;
  • bradycardia;
  • arrhythmia;
  • nausea.

Signs of a potassium overdose are:

  • slowing down of heart rate;
  • ECG change;
  • fatal hyperkalemia.

Potassium becomes toxic to patients with impaired adrenal function. Patients with craniocerebral trauma or slow conduction of heart impulses during therapy with polarizing droppers should be constantly monitored by a doctor. The composition of the systems must be introduced as slowly as possible so as not to lose the patient from severe hyperkalemia.

Indications for use

A polarizing electrolyte solution works best when:

  • joint therapy with antihypertensive and diuretics;
  • vomiting and prolonged diarrhea;
  • complex poisoning;
  • intoxication with cardiac glycosides;
  • ischemic heart disease;
  • arrhythmias;
  • extensive necrosis;
  • disturbed heart rhythm;
  • ventricular tachycardia;
  • progressive myocardial infarction;
  • acute coronary syndrome;Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology
  • heart failure.

The polarizing mixture, the composition of the dropper may vary, is prepared based on the results of biochemical and electrolyte blood tests. The drug solution is intended for intravenous administration. Its remains are not stored, but disposed of immediately. The electrolyte compound is not prescribed for adolescents under 18 years of age, as well as for pregnant women.

A complex mixture with electrolytes and insulin is prescribed for patients with acute heart attacks. The therapy with polarizing droppers increases the potassium and glucose readings in the blood from the very first application. Treatment is individualized, taking into account all the dangers and prescriptions. With obvious benefits for the patient, the specialist uses the remedy, controlling the condition of the disease.

Active polarizing therapy is suitable for feeding the heart with electrolytes and glucose. Panangin or magnesium in ampoules can be added to its main 3 components. Such polarizing mixtures differ in proportions and are used to get rid of electrolyte deficiencies. They are also prescribed for the complex treatment of rhythm disorders and glycoside intoxication.

The effect of droppers with a polarizing composition is due to an increase in metabolism and potassium parameters in cardiomycytes. With oxygen deficiency, the electrolyte quickly enters the cells. Under the influence of glucose and insulin, it accumulates in them, due to which the reaction to excitatory factors and polarities is stabilized.

Therapy with polarizing compounds:

  • heals heart tissue damage caused by ischemia;
  • weakens necrosis;
  • reanimates the heart rate;
  • restores the condition of patients with heart failure.

At normal levels of magnesium and potassium in the blood, polarizing droppers are replaced with cordarone or lidocaine. These drugs are more effective and do not cause an excess of electrolytes. Apply 200-400 ml of the polarizing mixture during the day. This rate is recommended by cardiologists. It is administered by drip, intravenously.

With an increase in potassium in the bloodstream to 7 mmol per liter, the following occurs:

  • violation of the heartbeat;
  • muscle weakness;
  • weakening of the pulse;
  • rapid breathing;
  • thirst;
  • fainting;
  • strong urination;
  • numbness of the legs and arms;
  • mental disorders;
  • stomach pain;
  • lowering blood pressure.

If such side effects appear, then treatment with polarizing agents is discontinued. Instead, sodium chloride and diuretics are prescribed to quickly get rid of potassium in the blood.

Cardiologists and neurologists, when prescribed therapy with a polarizing mixture, must necessarily monitor patients with craniocerebral trauma and delayed conduction of impulses to the heart. Bottles with electrolytes are used once. Reuse of their content is not allowed. During the course of therapy, constant monitoring of ECG indicators and blood glucose levels is performed.

The rapid introduction of droppers with polarizing contents is strictly prohibited, as this is always fatal. The composition of a complex treatment mixture is variable. He is appointed, taking into account the information about the examination of the patient. Only with this approach undesirable effects from the use of a polarizing composition are excluded. It is known that intensified therapy with such mixtures decompensates the state of the myocardium and is very harmful for patients.

The polarizing mixture (the composition of the dropper and its purpose are inextricably linked) is suitable for the treatment of neurological and cardiological pathologies. The multicomponent solution helps to stabilize the heart rate and prevent the development of heart attacks. Together with this, the constituent funds stop myasthenia gravis.

Contraindications for use

Contraindications to the use of a polarizing agent are:

  • the presence of severe burns;
  • excess or sufficient amount of electrolytes in the blood:
  • intestinal obstruction;
  • diabetes;Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology
  • swelling of the brain;
  • impulse blockade phenomena in the myocardium;
  • renal failure;
  • deficiency of sodium and blood circulation;
  • acidosis or oxidation of the blood.

When intoxicated with a polarizing mixture, the following can be observed:

  • violations of the pulse and heart rhythm;
  • muscle weakness;
  • a strong need to drink;
  • fainting;
  • profuse urination;
  • numbness of hands and feet;
  • mental disorders;
  • stomach pain;
  • hypotension.

The polarizing agent is not prescribed:

  • adolescents under 18;
  • pregnant women;
  • during the lactation period.

Method of administration and dosage

In cardiology, patients are injected with a polarizing mixture once a day.Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology

Droppers with it should contain:

  • insulin (8 units);
  • 10% glucose (250 ml);
  • potassium chloride (40 g).

A complex mixture has the following qualities:

  • reduces the risk of death by 12%;
  • improves blood circulation;
  • changes the state of the electrolyte balance;
  • corrects the heart rate.

Along with the polarizing mixture, angina pectoris is treated:

  • Antianginal drugs that weaken the heart's need for oxygen and promote the growth of its molecules in the blood. These tools include:
  1. beta blockers, which prevent the development of ischemia;
  2. calcium antagonists;
  3. nitrates.
  • Antiplatelet agents that thin the blood.
  • Statins.
  • Diuretics.
  • Cardiac glycosides.

In the treatment of neurological disorders using a polarizing mixture, the amount of potassium in the blood is controlled. If it suddenly rises, then this component is removed from the product or its dose is adjusted.

Together with the described control, they also monitor:

  • the clinical condition of the patient;
  • acid-base balance;
  • ECG;
  • electrolytes.

All these actions are performed for the timely recognition of hyperkalemia, which appears quickly and without symptoms. From an overabundance of an element in the body, heart block develops inside, and even death may occur.

In neurology, treatment with non-depolarizing muscle relaxants is often used instead of the described complex mixture for droppers. These drugs regulate the production of histamine and affect the autonomic nervous system.

They included:

  • arduan;
  • nimbex;
  • trakrium;
  • esmeron;
  • mivacron.

In intensive care, a polarizing mixture is used to avoid:

  • postoperative complications;
  • weakening of cardiac output;
  • oxygen deficiency in tissues.
    Polarizing mixture. The composition of the dropper, what is it in cardiology, neurology
    Polarizing mixture

Resuscitators give their patients with craniocerebral trauma or intoxication shock polarizing droppers not with potassium, but with Panangin. Sometimes asparkam may be prescribed instead. In this case, glucose is taken at 10%, since its 5% solution can lead to cerebral edema or death.

In intensive care, polarizing droppers should include:

  • insulin (6-8 units);
  • 10% glucose (150 ml);
  • panangin or asparkam (up to 80 ml).

Patients in a very serious condition with arrhythmia or vascular insufficiency are injected with a mixture of 60 units. insulin and 50% glucose. For those who have a satisfactory condition, 40 units. insulin is dissolved in 18% glucose. Further, patients are supported with a polarizing mixture with 20 units. insulin and 10% glucose.

The lack of potassium is calculated as follows:

K (in mmol) = human weight (in kg) x 0.2 x 2 x 4.5

As a result, after calculations, 4% potassium chloride is obtained, which is dissolved up to 500 ml with injection water (1 to 10) or 5% glucose. Severe poisoning requires the dissolution of 4% potassium in 40% glucose. The usual dose, which experts advise, does not exceed 20 mmol of electrolyte per hour or 2-3 mmol of potassium per 1 kg of a person's weight per day.

The dosage of the polarizing mixture in each specific case may be different. The use of droppers with this agent reduces mortality from cardiovascular diseases by 12%. The composition of a complex preparation is often supplemented and corrected to enhance the therapeutic effect.

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