Vasobral. Instructions for use, price, reviews

Vasobral is an effective drug that belongs to the pharmacological group of drugs, designed to improve blood circulation in the tissues of the brain. This medication has pronounced vasodilating properties, which is reflected in its instructions for use. Vasobral is prescribed as the main or auxiliary agent in the treatment of cerebrovascular disorders.

Release form

Vasobral is a drug that comes in the form of flattened white round tablets. On both sides of the medication, its name is embossed in Latin letters. The preparation is packed in plastic blisters of 10 tablets. The main packaging of Vazobral is a cardboard rectangular box, inside which, along with the tablets, detailed instructions for their use are enclosed.

Composition of the preparation

The table below lists the constituent components of Vasodilator Vasobral.

Alpha dihydroergocriptine mesylate	not more than 4 mg
Caffeine	within 40 mg
Magnesium stearate	1.5 mg
Silica	0,4 mg
Microcrystalline cellulose	60 mg
Lactose monohydrate	94.1 mg

Vasobral is a drug that has a simple but effective composition. The main and auxiliary substances of this medication are used in therapeutic dosages that are safe for the human body.

Pharmacological properties

Vasobral (the instructions for use of the product contain comprehensive information on the action of its components) is a drug with a combined composition that blocks alpha1 and alpha2-adrenergic receptors.

This medication has the following pharmacological properties:

• slows down the process of interaction of platelets;
• makes the walls of blood vessels more dense;
• increases the number of efficient capillaries;
• stimulates blood circulation and intracellular metabolism in brain tissues;
• increases the threshold of resistance of the central nervous system to the effect of hypoxia;
• acts as a psychostimulant and serotonergic agent;
• helps to improve the performance of skeletal muscles and the brain;
• suppresses the feeling of drowsiness and loss of strength;
• creates the effect of cheerfulness;
• activates the centers of the brain responsible for the reflexes of the cardiovascular and respiratory systems;
• acts as a diuretic.

Vasobral increases the degree of excitability and conductivity of the tissues of the spinal cord, which has a positive effect on the work of the entire central and peripheral nervous system. A feeling of vigor, an increase in physical and mental activity is felt in the first days from the beginning of the regular intake of this remedy.

Pharmacodynamics and pharmacokinetics

The combined drug Vasobral is rapidly absorbed into the walls of the gastrointestinal tract after oral administration. The active substance dihydroergocriptine is absorbed several times more actively under the influence of caffeine. Already after 30 minutes. after taking one dose in the patient's blood, the maximum concentration of the active components of this agent is observed. Biochemical breakdown of Vasobral occurs in the liver tissues with further excretion of its metabolites outside the body through the organs of the excretory system.

Indications for use

Vasobral, the instructions for use of which contains comprehensive information about the properties of the drug, is used to treat patients with the following diseases and pathological conditions of the body:

• cerebrovascular insufficiency caused by complications of concomitant diseases of the brain and blood vessels;
• negative consequences of progressive disorders of local blood circulation in certain areas of the brain;
• Meniere's disease;
• dizziness attacks;
• tinnitus and hypoacusia, the appearance of which has an ischemic nature of origin;
• cerebral atherosclerosis of blood vessels that disrupted the performance of the brain.

In the therapeutic process, Vasobral is used as the main or auxiliary agent to restore full blood circulation in the blood vessels of the brain. The duration and treatment regimen for cerebrovascular disorders depends on the severity of the pathology, as well as the reasons that provoked its occurrence.

Contraindications

Vasobral (instructions for the use of this agent were compiled after repeated clinical studies of its components) is well tolerated by most patients of different age categories.

The use of this drug for therapeutic purposes is contraindicated in the presence of the following circumstances:

• individual intolerance to the constituent substances of the drug, which is manifested by an acute or moderate allergic reaction;
• pathologies of the cardiovascular system detected at the stage of diagnostic examination using the echocardiography method;
• congenital or acquired heart valve defects.

Vasobral is not recommended for use in women who are pregnant or breastfeeding a newborn baby. Clinical studies on the safety of this drug for the fetus and infant have not been conducted.

At what age can the drug be used?

Vasobral is used to treat patients of the adult age category. There is no laboratory evidence that this vasodilating agent is safe for the child's body.

Instructions for use, dosage

Vasobral, the instructions for the use of which establish the order of therapy, are taken throughout the continuous therapeutic course. Unauthorized and early termination of treatment with this medication may cause the absence of a positive effect from the action of the constituent substances of this drug. The dosage regimen of Vasobral is determined by the doctor, but largely depends on the severity and type of the disease.

With migraine

For the treatment of attacks of severe headache, which is caused by ischemic disorders in the tissues of the brain, use a course of Vasobral with a dosage of 0.5 to 1 tablet 2 times a day. The medication is washed down with a small amount of plain water without gas. The duration of the therapeutic course depends on the nature of the origin of the migraine.

It is extremely important that at the stage of diagnosing headache attacks, the causes of ischemic disorders in the brain tissues are established. The persistence of factors contributing to the onset of migraine becomes the reason for the decrease or absence of the therapeutic effect of treatment with Vasobral.

In case of impaired venous outflow

Cerebrovascular syndrome caused by impaired venous outflow from the brain tissue is eliminated by medication activation of local blood circulation and increasing the level of wall permeability capillaries. In the presence of this pathology, the patient is prescribed to take Vasobral in half or a whole tablet from 1 to 2 times a day.

The medicine is drunk with meals. The duration of the therapeutic course is about 2 months. At all stages of treatment, the patient undergoes a diagnostic examination in order to restore full blood circulation in the brain tissues with the normalization of previously impaired venous outflow.

With cervical osteochondrosis

In the instructions for use of Vasobral there are no direct indications for the use of this agent in the treatment of chronic osteochondrosis of the cervical spine. This drug can be used if this disease of the musculoskeletal system has led to compression of the great vessels supplying the brain.

To eliminate signs of hypoxia of the central nervous system and restore a stable blood supply to its tissues, it can be a course reception of Vasobral was prescribed in a dosage of 1/2 or 1 tablet of a medication with a duration of treatment from 60 to 90 days. The drug is taken up to 2 times a day during a meal. If necessary, repeated treatment is carried out 1-2 times during the year until the symptoms of ischemia of the brain tissues disappear completely.

Side effects

Clinical studies of Vasobral have shown that the following side effects may occur as a result of taking this vasodilating agent:

• severe nausea (a similar symptom manifests itself especially often in people who take Vasobral tablets on an empty stomach in the morning);
• a sharp decrease in blood pressure indicators;
• heart palpitations that persist even in conditions of physical calm;
• violation of the process of blood regurgitation;
• acquired defects of the heart muscle;
• the appearance of pathological effusion inside the pericardium;
• dyspepsia and severe gastralgia (in the event of this side effect, a special withdrawal of the drug is not required);
• attacks of severe headache, which intensify against the background of a decrease in blood pressure;
• increased excitement of the nervous system;
• dizziness, the presence of which can cause physical weakness, impaired coordination of movements;
• hives;
• itching of the skin surface of the body;
• the formation of edema of epithelial tissues;
• the appearance of a red or pink rash.

The presence of the last symptoms indicates that the patient's body exhibits an allergic reaction to the constituent components of the drug. The manifestation of side effects is the basis for the immediate cancellation of further administration of the vasodilating agent Vasobral.

Attacks of an acute allergic reaction will require additional antihistamine therapy. Patients with signs of side effects from treatment with Vasobral need to undergo additional examination by their attending physician.

Overdose

Vasobral (instructions for use of the medication contains comprehensive information on its quality characteristics) should be taken in strict compliance with the prescribed dosage regimen.

Exceeding the therapeutic doses of the drug leads to the development of the following symptoms and pathological conditions of the body:

• bowel disorder;
• loss of appetite;
• vomit;
• dizziness attacks;
• lowering blood pressure;
• pain and discomfort in the abdominal cavity;
• dizziness;
• manifestation of allergic reactions with varying degrees of saturation.

Elimination of signs of an overdose with Vasobral tablets is carried out on an outpatient basis or in conditions hospital toxicology department, depending on the general condition of the patient and the dose taken medication.

Patients in this category receive complex symptomatic therapy aimed at cleansing the patient's gastrointestinal tract and blood from an excess amount of the constituent components of this drug. In most cases, antihistamines, sorbents, intravenous infusion with a saline solution are used to restore the water-electrolyte balance.

special instructions

Provided there are no side effects, Vasobral has the ability to dilate blood vessels without simultaneously lowering blood pressure. The appointment of a regular intake of this medication for patients who suffer from arterial hypertension requires the continued use of antihypertensive drugs.

Otherwise, there is a real risk of a hypertensive crisis with further complications. The active substance caffeine, contained in the combined composition of Vasobral, can cause sleep disturbances, as well as short-term attacks of tachycardia. To minimize the risk of side effects from the digestive system, it is recommended to refrain from taking this medication on an empty stomach.

In patients who have been taking the active substance of this drug dihydroergocriptine for a long period of time, the following pathological symptoms were observed:

• development of constrictive pericarditis;
• fibrosis of the lung tissue;
• the appearance of effusion in the pleural cavity and pericarditis.

Patients who develop pleuropulmonary disorders of unknown etiology during prolonged therapy, are subject to a comprehensive examination for a more detailed study of the functional state of the lungs, pleural cavity and heart muscle. At the time of diagnosis of the patient, therapy with Vasobral is stopped. At this stage of treatment, the patient is contraindicated to take drugs based on dihydroergocriptine.

In clinical practice, rare cases of retroperitoneal fibrosis have been reported in patients who have taken large doses of Vasobral for a long period of time. The first signs of this pathology are attacks of aching pain in the back, from the kidneys, edema of the lower extremities.

In the case of diagnosing the slightest changes in the patient's retroperitoneal space with the appearance of suspicions of tissue fibrosis, further therapy with Vasobral is stopped. Professional athletes taking part in competitions should remember that the components of this medication contain active substances that give a positive reaction during doping control.

The drug Vasobral can cause a side effect in the form of dizziness and a decrease in blood pressure. Such symptoms cause a deterioration in the severity of the reaction and attentiveness. In this regard, for the period of treatment with Vazobral, it is recommended to refrain from driving all types of vehicles, and also not to perform work with increased danger.

Drug interactions

The simultaneous administration of Vasobral and medicines with antihypertensive properties can cause a decrease in blood pressure. In this regard, during the entire period of therapy, it is recommended to carry out regular measurement of blood pressure indicators. Caffeine, which is part of the combined composition of Vasobral, weakens the pharmacological properties of sleeping pills.

Analogs

The drug Vasobral is produced by the Italian pharmaceutical company Chiesi. Analogs of this medication are presented on the domestic market, which have exactly the same pharmacological properties.

Cofetamine

The drug Kofetamin is produced by the Russian company OAO Tatkhimfarmpreparaty. This is a medication that comes in the form of tablets, coated with a layer of protective shell with the active substances ergotamine and caffeine.

This tool has the following properties:

• activates the functions of the brain;
• stimulates the efficiency of the central nervous system;
• increases the frequency of contraction of the heart muscle;
• has a cardiotonic effect;
• leads to a contraction of the walls of blood vessels.

Kofetamin is prescribed for taking 1 tablet 2 to 3 times a day. This drug is indicated for use for a short period of time. The maximum duration of the course of therapy with Cofetamine is 7 days. After this period of time, it is necessary to take a break for a period of 4 days. The average cost of Cofetamine is 192 rubles. for 10 tablets.

Huato Boluses

Huato boluses are a phytotherapeutic analogue of Vasobral. This medication has a completely different composition, but at the same time it has an identical effect on the correction of cerebral circulation disorders.

Boluses Huato comes in the form of pills with a completely natural composition, which includes extracts of medicinal plants of the following types:

• Japanese sophora;
• Activated carbon;
• Chinese wolfberry;
• Dahurian angelica;
• Bee Honey;
• Japanese ophiopogon;
• ginseng.

Huato boluses are packaged in 80 g cans. A dosing spoon is included with each package.

The constituent components of Huato Boluses pills have the following effect on the human body:

• restore microcirculation of blood in the tissues of the brain;
• improve memory;
• increase the level of mental and physical activity;
• eliminate the pathological consequences of a stroke;
• stimulate intracellular metabolism of brain tissue.

Boluses Huato are taken orally in 4 tablespoons (dosing) 2 times a day after 30 minutes. after eating. Every 10 days, it is necessary to take a break of 24 hours to prevent the occurrence of side effects. The average duration of the course of therapy is from 2 to 6 months.

Nootropil

Nootropil is a drug with similar properties, but with a different chemical composition. This medication is available in the form of tablets, the active substance of which is piracetam in a dosage of 800 and 1200 mg.

Nootropil has the following effect:

• improves cerebral circulation;
• stimulates the functions of the central nervous system;
• acts as a psychostimulant;
• increases concentration and performance;
• prevents the occurrence of spasm of blood vessels;
• reduces the level of blood viscosity.

Nootropil is prescribed to be taken in a dosage of 1-2 tablets from 2 to 3 times a day. This drug should be taken with food or on an empty stomach. The timing of therapy is determined by the attending physician. The average cost of Nootropil is from 249 rubles.

Terms, conditions of sale and storage

Vasodilator Vasobral is available only with a doctor's prescription. The storage of this medication is carried out in a temperature range from +15 to +25 degrees Celsius. The drug should be kept in a dark and cool place away from children. The shelf life of Vasobral is 4 years, after which further medication is prohibited.

Price

The average cost of the drug Vasobral is 981 rubles. per pack of 30 tab. Vasobral is a vasodilating tablet formulation that is prescribed for regular admission to patients with cerebrovascular disorders. This drug has a psychostimulating effect, increases blood circulation in the tissues of the brain, reduces signs of CNS hypoxia, increases mental and physical activity.

Vasobral proved therapeutic efficacy in the treatment of ischemic pathologies of the brain that developed against the background of atherosclerosis of the blood vessels. The average duration of a continuous course of treatment with Vasobral is from 2 to 3 months, which is enshrined in its instructions for use.

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