Mirvaso Derm gel. Reviews, before and after photos

Mirvazo Derm is a medicine used for various dermatological diseases. The gel has a good healing effect and has many positive reviews.

Indications for use

The medicine is used in the treatment of erythema, the development of which is due to rosacea. The drug should be used only after confirming the diagnosis.

Chemical composition

The active ingredient is brimonidine tartrate.

Additional composition:

• carbomer;
• preservative E218;
• phenoxyethanol;
• food additive E171;
• glycerol;
• propylene glycol;
• caustic soda;
• filtered water.

Thanks to the complex action of all ingredients, a therapeutic effect is achieved.

Release form

The medicine is produced in Switzerland in the form of a gel for external use. Description: a mass of light yellow or white. The product is contained in plastic tubes and packed in cardboard boxes. Gel prices may vary slightly depending on the region of sale and the pharmacy chain.

Region / region	Dosage form / dosage	Price
Moscow, Moscow region	Gel, 0.5%, 10 g	RUB 2150-2200
St. Petersburg	Gel, 0.5%, 10 g	RUB 2200-2300
Saint Petersburg (suburbs)	Gel, 0.5%, 30 g	RUB 1440-2940
Leningrad region	Gel, 0.5%, 10 g	RUB 2190-2210
Novgorod region	Gel, 0.5%, 30 g	RUB 1670-2000

You can find out the exact cost and purchase the medicine at any private or public pharmacy located in your place of residence.

Pharmacodynamics

The drug belongs to the group of alpha2-adrenergic drugs. The structural similarity of the main component is 1000 more compared to the similarity of alpha1-adrenergic receptors.

The drug has a pronounced local vasoconstrictor effect, which leads to a decrease in symptoms caused by the development of erythema.

Pharmacokinetics

With the systematic application of the gel for 1 month in the indicated dosages, its components were not detected in the blood. The active ingredient is metabolizable in the liver. The substance and its metabolites are excreted mainly by the renal system.

Application

The product is intended for external use only.

Dosage regimen: applied to all areas of the face once a day. Moreover, the maximum daily dosage should not exceed 1 g.

The duration of therapy is individual, according to the indications of the attending physician.

For children under 18

The drug is prohibited for use in children.

For adults

Adults are prescribed treatment according to the general scheme: the agent is applied to the affected areas once a day. The duration of the course is according to the recommendations of a dermatologist.

For pregnant

In pregnant women, therapy is carried out according to the general scheme. This should take into account the expected benefits and perceived risks.

For the elderly

The medication can be prescribed to elderly patients. No dosage adjustment is required. Treatment is carried out according to the general scheme - once a day. The duration of the course is individual.

Contraindications

Mirvazo Derm gel (reviews of the drug are mostly positive) should be used only in the absence of contraindications and with the permission of a dermatologist. The drug has some restrictions, in the presence of which you should refuse to use it, as this can complicate existing diseases or lead to the development of additional complications.

Contraindications:

• intolerance to the components;
• age under 18;
• combined use of MAO inhibitors, tri- and tetracyclic antidepressants.

In these conditions, it is recommended to choose another remedy. The drug is prescribed with extreme caution during pregnancy, as well as for functional disorders of the kidneys and liver.

Overdose

There is no information on drug overdose with local use.

If the gel is accidentally swallowed, the following symptoms may develop:

• lowering blood pressure;
• general malaise;
• vomit;
• violation of heart rhythms;
• inhibited state;
• apnea;
• constriction of the pupils;
• signs of hypothermia;
• convulsive state;
• oppression of respiratory functions.

At the moment, only 2 cases of the development of negative reactions have been registered in case of accidental ingestion of the gel. Moreover, these cases were observed in young children. The undesirable symptoms caused by the use of the drug disappeared on their own within 24 hours. With the development of an overdose, symptomatic and supportive therapy is prescribed, aimed at improving airway patency.

Side effects

Mirvazo Derm gel (patient reviews report that the drug has no withdrawal syndrome) in most cases is well tolerated and does not cause addiction and other undesirable manifestations. Adverse reactions occur extremely rarely and are associated with the individual characteristics of the patient's body and the influence of active components.

Side effects:

• Central nervous system: In rare cases, headaches and numbness of the body (loss of sensation) occur.
• Visual function: swelling in the eyelids.
• Cardiovascular system: hot flashes, lowering of blood pressure.
• Respiratory system: nasal congestion is extremely rare.
• Digestive organs: dryness of the mucous membranes of the oral cavity.
• Skin manifestations: hyperemia, signs of irritation, itchy elements, burning sensation, pallor (in places where the gel is applied). Occasionally dermatitis (contact or allergic type of disorder), rosacea may develop. You may also experience a feeling of dryness or warmth, discomfort, pain, acne symptoms, and rashes. In more rare cases, the drug can lead to the development of puffiness on the face, hives, or Quincke's edema.
• Other reactions, including local signs: hot or cold sensation in the area of ​​application of the medicine.

  

In the event of the development of the listed signs, as well as other symptoms not noted in the instructions, it is recommended to stop further use of the drug and seek medical advice.

Special recommendations

Avoid using the product in the area around the eyes, as well as in areas where there is a violation of the integrity of the skin. The drug can be used in conjunction with other drugs or cosmetics intended for the treatment of rosacea. Such funds are used after application and drying of the main gel.

The therapeutic effect gradually decreases and completely disappears a few hours after application. In some cases, there was an increase in the symptoms and severity of the disease after the end of the drug. Similar manifestations were observed during the first 2 weeks of therapy. It is extremely rare that the drug led to hot flashes, which passed on their own after the drug was discontinued.

If the condition worsens, treatment should be discontinued. In this case, it is necessary to carry out symptomatic therapy, which includes taking antihistamines, NSAIDs, as well as lotions with a cooling effect.

With repeated use of the gel (after undergoing symptomatic therapy), the severity of hot flashes and the underlying disease increased. In this connection, after the drug is discontinued when it is used again, it is recommended to start treatment with preliminary application of small doses of gel. Apply in this way locally for 1 day.

If the agent is well tolerated, the therapy is resumed and the agent is applied to the entire surface of the face. Requires strict adherence to the established dosages. The gel mass is applied once a day in a very thin layer. The combined use of a drug with its antagonists can lead to the occurrence and increase of adverse reactions.

Moreover, similar effects develop in the following groups of patients:

• severe disorders in the cardiovascular system;
• depressive conditions;
• insufficient blood circulation in the brain or coronary vessels;
• Raynaud's syndrome;
• Sjogren's disease;
• hypotension (orthostatic disorder);
• Burger's disease.

The medicine is intended for local use and does not have a negative effect on the psyche and visual functions. a person, therefore it is allowed to drive a car or carry out other work that requires the speed of psychomotor reactions.

Drug interactions

Mirvaso Derm can interact with other medications. Patient reviews indicate the need for prior consultation with a dermatologist before the combined use of the gel and other erythema treatment. It is assumed that MAO inhibitors can lead to impaired absorption of the main substance and amines, which, in turn, increases the risk of side effects.

The effect of the active ingredient can increase with the combined intake of the following drugs and substances:

• ethanol;
• anesthetics;
• barbiturates;
• opiates;
• sedatives.

It is recommended that a high degree of caution be exercised when using drugs with agents whose action is aimed at increasing the level of amines in the blood and enhancing their metabolic reactions.

It is necessary to use the gel extremely carefully at the beginning of therapy or when changing daily dosages in conjunction with drugs (local or systemic), which have the opposite effect in relation to the drug and have an effect on alpha adrenergic receptors.

In rare cases, a medication can lead to a slight decrease in blood pressure, which should be taken into account when using it simultaneously with the following drugs:

• brimonidine;
• cardiac glycosides;
• medicines that lower blood pressure.

When using other drugs during the period of prescribing the medication, you should inform the treating person about this in advance. doctor, which will avoid drug incompatibility and, as a result, prevent the development of negative reactions.

Storage conditions and periods

• The gel should be stored in a dark and dry place at temperatures up to 30 ⁰C.
• Expiration date - 6 months from the date of issue.
• Do not use after the expiration date stated on the package.

Conditions of dispensing from pharmacies

Terms of sale - over the counter.

Analogs

The medication in some cases can lead to the development of intolerance reactions. If such effects occur, it is recommended to replace it with another remedy similar in indications and action. The selection of generics should be handled by the attending physician. It is not recommended to prescribe and use substitutes on your own, since an incorrectly selected drug can worsen the condition and cause the development of additional complications.

Solantra

Mirvazo Derm gel (reviews of patients and doctors report a high therapeutic effect of analogues and the main drug) should replace with other drugs, taking into account the severity of the disorder, the tolerance of the components and other physiological characteristics the patient.

This product is made in Switzerland in the form of a cream for external use, the active ingredient of which is ivermectin. The drug has a pronounced anti-inflammatory, antiprotozoal and antimicrobial effect. It is used in the treatment of inflammatory processes caused by the development of rosacea (including the formation of papules and pustules).

Application scheme: apply a thin layer to the affected areas and leave until completely absorbed. The number of uses per day - 1 time. The duration of therapy is 4 months. If necessary, after a break, treatment can be repeated. However, before that, you should consult a specialist. In the absence of effectiveness within 3 months, therapy should be discontinued and a doctor should be consulted.

Restrictions on the appointment:

• intolerance to the components;
• pregnancy;
• lactation period;
• age up to 18 years.

Extremely carefully and only under the supervision of a physician, the cream can be used by patients with functional disorders of the liver. No dosage adjustment is required. Terms of sale - over the counter. The price of a medicine in public and private pharmacies in Russia is 830-1305 rubles.

Skinoren

This substitute is produced in Italy in the form of a gel or cream for external use.

The active ingredient is azelaic acid.

Recommendations for the appointment:

• acne rash of mild to moderate severity;
• increased skin pigmentation (for example, chloasma);
• rosacea (including the formation of pustules and papules).

Dosage rules: apply to the affected areas and leave until completely absorbed. Apply 1-2 times a day. The duration of the course depends on the form and severity of the disorder and can vary from 1 to 4 months. If necessary, after the interval, it is possible to carry out a second course.

Contraindications:

• intolerance to the components;
• children under 12 years of age (with acne);
• minor age (with other dermatological problems).

With extreme caution, the agent should be prescribed to patients with bronchial asthma. In this case, therapy should be carried out under the supervision of a specialist. During pregnancy, as well as during breastfeeding, the drug is used taking into account the potential risks and expected benefits. In this case, constant supervision by a doctor is also required. Vacation conditions - over-the-counter. The cost of the drug in regional and regional pharmacies in Russia varies from 640 to 1530 rubles.

Rosamet

Mirvazo Derm gel (reviews and action of similar drugs may differ significantly from the main medicine) can be replaced by such a popular and sought-after remedy as Rosamet. This generic is produced in Croatia as a topical cream. The active ingredient is metronidazole.

The drug belongs to the group of antiprotozoal agents with antibacterial activity. It is effectively used for various dermatological diseases caused by pathogenic microorganisms. The indication for the use of the product is acne and rosacea. Dosing schedule: pre-clean the skin and gently apply the cream. Used 2 times a day. The duration of therapy is from 3 to 4 months. If necessary, after a break, you can re-treat.

Restrictions:

• intolerance to the components;
• childhood.

During pregnancy and breastfeeding, the drug is used only with the permission of a doctor, taking into account the expected benefits and perceived risks. The way of implementation is over-the-counter. The cost of a medicine in commercial and state pharmacies in Russia is 195-250.

Metrogyl

This analogue is produced in India in the form of a gel for external use. The active ingredient of the drug is metronidazole. The drug has a pronounced antimicrobial, antiprotozoal and antibacterial effect.

Application area:

• rosacea (including acne formed after the use of steroid drugs);
• acne vulgaris;
• the presence of bedsores;
• seborrheic dermatitis;
• the formation of hemorrhoids;
• sluggish healing wounds.

Application scheme: apply a thin layer to the affected area. They are used 2 times a day - in the morning and in the evening. The duration of treatment is from 3 to 9 weeks. The maximum course duration is 3-4 months. The therapeutic effect is observed already after the first 3 weeks of using the gel. The drug is not prescribed in case of poor tolerance of the components that make up its composition.

With extreme caution, the agent is used in the 1st trimester of pregnancy, as well as during breastfeeding. In these cases, therapy is carried out under the close supervision of a specialist. The way of implementation is over-the-counter. The cost of the gel in pharmacies in Moscow and the Moscow region is 170-220 rubles.

Before using Mirvaso Derm, you must consult with a specialist and carefully study the instructions for using the gel. Additionally, it is recommended to read the reviews of those who have already taken the drug.

Video about the drug Mirvazo

Mirvaso rosacea whitening cream: