Vicasol in ampoules. Price, instructions for use, reviews

Vikasol is a hemostatic drug, used in the diagnosis of diseases accompanied by bleeding. Medicine in ampoules is prescribed even in advanced cases, its price is affordable. This allows, if necessary, to undergo a full-fledged therapeutic course. The medicine is prescribed by the doctor after examination, which somewhat reduces the likelihood of complications.

Release form

The drug is sold in the form of a solution for parenteral administration, which is packaged in small clear glass ampoules. 1 ampoule can contain 1 ml of solution. It is transparent and colorless, has no pronounced aroma or sediment. A small cardboard box contains 10 ampoules. They can be placed in plastic or cardboard boxes. The product is accompanied by a description found in the box. On drugstore shelves, you can also find the drug in the form of tablets for oral use, but more often it is the solution that is used.

Chemical composition

Vicasol in ampoules (the price of the medication is available for patients) and in another dosage form contains the substance menadione sodium bisulfite. It has a major therapeutic effect on the body.

The medicine in the form of a solution contains auxiliary ingredients in the form of sodium chloride and purified water. The amount of the main component in 1 ml of solution is 10 mg.

Pharmacological properties

The drug has hemostatic properties, that is, it helps to stop bleeding of various origins and prevents profuse blood loss in case of tissue damage. The medicine is used in the diagnosis of severe bleeding, since the effect is quite pronounced.

The drug also has a coagulating effect, stimulates the formation of a blood clot, which is important to prevent the loss of large amounts of blood in tissue injuries.

Pharmacodynamics and pharmacokinetics

The action of the drug does not begin immediately after its parenteral administration, since the effect appears 6-8 hours after the application of a single therapeutic dose. The main ingredient of the composition is fat-soluble vitamin K, with a lack of which bleeding develops.

After the drug enters the body, various changes occur, which lead to stopping bleeding:

• The main substance takes part in the synthesis of prothrombin, which stimulates the formation of blood clots and stops bleeding.
• When the component spreads through the systemic circulation, the production of clotting factors of various types increases, which also helps to reduce the amount of blood secreted.
• The drug improves the general condition, which is disturbed as a result of profuse blood loss.
• With the course application, not only the cessation of bleeding is noted, but also a positive effect on tissues, blood vessels, which prevents the re-development of symptoms.

Parenteral administration of the drug leads to its rapid entry into the systemic circulation and spread throughout the body. The first effect is noticeable after 6-8 hours, but the maximum effect develops only after 12-18 hours. That is why the medicine is not used for acute severe bleeding when immediate help is needed.

The component accumulates in a small amount in tissues and blood, which allows you to achieve the maximum therapeutic effect. Once effective, the ingredient is processed in the patient's liver. Its metabolites are evacuated by the kidneys within 1-2 days after the last dose.

If a patient has severe liver and kidney diseases, the process of processing and excretion of ingredients slows down. This can affect the therapeutic effect of the drug.

Indications for use

Vikasol is prescribed for various disorders, and its price allows patients to undergo a full course.

The medicine in ampoules has the following indications for use:

• Hemorrhagic syndrome of various origins.
• Bleeding that is not accompanied by shock. This is due to the fact that the drug does not have the quick effect that is necessary to help the patient.
• Bleeding trauma. If the patient develops arterial bleeding, the drug is used only as an adjunctive treatment.
• Diagnosing low levels of vitamin K in the body.
• Heavy and prolonged menstrual bleeding.
• Hepatitis, cirrhosis of the liver and other diseases that may be accompanied by increased bleeding.
• Prolonged diarrhea with bleeding, developing against the background of any infectious disease.

The drug is often prescribed in combination with other drugs in order to increase the effectiveness of treatment.

Contraindications

Despite its effectiveness, the solution cannot always be used for patients. An important absolute contraindication is considered intolerance to the ingredients in its composition.

Other barriers to therapy include the following conditions:

• Increased blood clotting in patients. At the same time, the use of the drug can provoke blood clots, which negatively affects the work of the entire cardiovascular system.
• Severe thrombophlebitis. Often the condition develops against the background of varicose veins. That is why the presence of such a disease is considered a reason for refusing solution therapy. If necessary, the doctor first identifies potential risks for the patient, and treatment is carried out only in short courses under the control of laboratory blood parameters.
• Acute conditions in which the use of medication does not help to quickly relieve symptoms. In this case, drugs are used to obtain a therapeutic effect over a short period of time.
• Severe course of hemolytic disease in newborns and adults.
• Acute violation of cerebral circulation and myocardial infarction in the acute stage. The drug can be prescribed only after the elimination of acute manifestations.
• Severe hepatic failure, accompanied by disruption of the organ.
• Acute kidney disease, in which the urinary system is disrupted.

The drug is prescribed with caution to patients with exacerbation of pathologies of the heart and blood vessels. The period of pregnancy is not considered an absolute contraindication for the use of the solution. The remedy is prescribed when an urgent need arises, as well as after consulting a doctor. The specialist individually decides on the prescription of the medicine.

During the period of breastfeeding, the drug is not used so often, only when acute symptoms appear and it is impossible to prescribe safer medicines. For elderly patients, the medicine is also prescribed with caution, especially if there is a history of chronic diseases of internal organs.

At what age can the drug be used?

Vikasol in ampoules (the price of the drug depends on the dosage form) is prescribed for patients older than 1 months, but if necessary, it can be used for newborns if specific indications. In each case, the decision on the use is made by the doctor after examining the patient.

Instructions for use, dosage

The drug in the form of a solution is intended for intramuscular administration when certain symptoms appear. Depending on the disease and related manifestations, the features of therapy, the dosage and duration of the course may differ.

Disease	Application features and dosage
Bleeding of various origins	For internal and external bleeding, the medicine is used for 3 days. For children under 1 year old, the dosage is 0.25 ml of solution. It is administered only once a day, preferably at the same time. Children over 1 year old can receive up to 0.5 ml of solution, patients over 2 years old receive 0.6 ml of solution. The dosage for children over 9 years old is 0.8 ml per day. Children over 14 years old and adults are prescribed from 1 to 1.5 ml of solution per day, depending on the severity of symptoms.
Liver pathologies as a result of destruction of an organ or penetration of a virus into it	For liver diseases, the remedy is usually used for adults. The daily rate does not exceed 1 ml of solution. It is administered at about the same time to achieve a stable concentration of the ingredient in the blood. The duration of use does not exceed 5 days, but if necessary, repeated courses can be prescribed after a 2-week break.
Uterine bleeding	In a mild form of violation, the drug is used in short courses of 3-4 days. A single dosage does not exceed 1.5 ml, but sometimes 1 ml of solution is enough for patients. Only a doctor can extend the course after examining the patient.

When administered intramuscularly, the standard rules are followed to avoid complications. Typically, the patient visits a hospital for the procedure, where the infusion is done by a specialist.

It is not recommended to carry out manipulations on your own at home, especially in the absence of the skills to administer solutions. Sometimes doctors allow a change in the daily dosage and duration of therapy, but the patient cannot make such a decision on his own.

Side effects

Vikasol in ampoules (the price of the drug may vary depending on the batch) can provoke negative reactions from the internal organs and systems. Most often, the blood system suffers, but other abnormalities may appear.

The most common complications:

• On the part of the nervous system, disorders are manifested in the form of headache and dizziness, as well as increased irritability and weakness. Often, patients notice rapid fatigue, decreased performance, and sleep disturbance. For several days, there is a deterioration in concentration and memory.
• On the part of the digestive tract, complications can develop even if all recommendations are followed. Patients may notice pain in the stomach and an increase in the acidity of gastric juice. If the patient has chronic pathologies of the digestive system, complications appear in an acute form, which worsens the general condition.
• Disorders of the urinary system are rare. They are accompanied by pain in the lower abdomen, increased urination and other abnormalities. Disorders especially often appear in the presence of any chronic diseases in the anamnesis.
• Most often, complications occur from the skin. Patients develop rash, irritation and scaling on the body and limbs. Over the course of several days, the symptoms may worsen, itching and burning are added. Patients scratch the skin, which leads to damage to its outer layer and the addition of infection.
• In some cases, disorders of the respiratory system develop, manifested in the form of shortness of breath, cough and bronchospasm. The condition is aggravated if the patient has bronchial asthma and other respiratory diseases.
• An increased risk of blood clots is considered a common symptom with the medication. It is possible to identify a deviation during a laboratory blood test after a course of therapy. When such a complication occurs, the patient may be prescribed anticoagulant therapy if the condition is severe and thrombus formation threatens the patient's life.

Allergic manifestations can affect the mucous membranes of the eyes and nasal passages. Patients report swelling, itching and redness. Lachrymation and rhinitis aggravate the general condition. Symptoms can manifest themselves in acute and subacute form, depending on the patient's condition, the duration of the course of the disease.

Overdose

Experts today have not registered cases of overdose with medication in the form of a solution or tablets. But this is not a reason for uncontrolled use in high doses without a doctor's prescription.

Doctors assume that with an overdose, all negative symptoms are aggravated, there is a significant deterioration in the general condition, complications from the vessels and the heart appear. If such deviations appear, it is recommended to immediately consult a doctor who will prescribe the correct treatment, taking into account the symptoms.

The patient does not always need to be in the hospital. Sometimes therapy is carried out at home. In case of severe symptoms, the patient is placed in a hospital, where an individual therapy regimen is selected. The medicine has no specific antidote, so the drugs are selected depending on the manifestations.

special instructions

Vikasol in ampoules (the price of a medicine may be higher when purchasing a large package) and tablets are usually not prescribed in long courses. If the patient needs it, it is important to constantly monitor blood counts.

To do this, the patient must visit a doctor at regular intervals, as well as donate blood for laboratory diagnostics. If a critical increase in clotting and platelet counts is detected, use should be discontinued.

If complications develop during therapy, it is not recommended to ignore them. It is better to visit a doctor immediately, who will determine the need for a specific treatment. Doctors draw the attention of patients to the fact that when diagnosing hemophilia, the drug does not help improve the condition of patients. With the development of such a disease, drugs with more pronounced properties are prescribed.

Drug interactions

The drug is not used simultaneously with drugs that have the same properties and contain the same ingredients in the composition. This can provoke complications, thrombosis, and other complications.

When used in combination with vitamin K antagonists, their action is blocked. Prescribing in combination with sulfonamides, some antibiotics requires a dosage adjustment of Vikasol, since complications from the blood system may develop.

Analogs

The medicine has analogues that can be prescribed if it is impossible to use it for various reasons. In most cases, the drugs have a different composition, but have a similar effect.

The most popular analogues:

• Etamsilat contains an active ingredient of the same name, which has hemostatic properties and helps to stop bleeding. The drug acts quickly, unlike the original. It is produced in the form of a solution for parenteral administration. The drug therapy regimen differs from that used when prescribing the original, since it can be prescribed in long courses.
• Tranexam contains another ingredient in the composition. It can be found in drug stores as an intravenous solution. The drug is considered very effective and can be used for acute bleeding. Unlike the original, the substitute acts quickly, therefore it is used as an emergency aid.

Substitutes for acute bleeding are considered more effective, but the doctor decides on the prescription of the medicine after a preliminary examination.

Terms, conditions of sale and storage

The drug is dispensed at the pharmacy after presenting a prescription form from a doctor. The maximum storage time is 3 years.

The product does not require special storage conditions, but it is better to exclude direct sunlight from entering the solution.

Price

The cost of the medicine is affordable for most patients and amounts to 80-110 rubles. per packing.

Vikasol is considered one of the most popular hemostatic agents. The drug in ampoules helps to stop mild bleeding, reduces the likelihood of complications. The price of the medication is affordable and, if necessary, each patient can undergo a course of therapy.

Video about the drug Vikasol

Vikasol ampoules description and instructions: