Suprastin during breastfeeding from allergies of mothers, children

Suprastin is a pharmacological agent for the treatment of allergies. The drug not only eliminates the signs of hypersensitivity, but also prevents their appearance, which is especially in demand in the prevention of pollinosis, rhinoconjunctivitis and other diseases. Suprastin, which is considered a relatively safe drug, is not recommended for breastfeeding.

Release form

The therapeutic line of Suprastin consists of tablets and a solution for parenteral administration. The latter is produced in the form of a transparent liquid without foreign inclusions, packaged in glass ampoules. The tablets are white, round, smooth at the fracture, placed in the cells of blisters made of aluminized foil.

The secondary packaging of the medicinal product is a cardboard box with instructions for use enclosed inside.

Chemical composition

The active substance is chloropyramine, a representative of the clinical and pharmacological group of antihistamine components.

To form the tablet base, the manufacturer used the following ingredients:

• gelatin;
• milk sugar in the form of a monohydrate;
• stearic acid;
• sodium starch glycolate;
• potato starch;
• talcum powder.

Excipients contribute to the gradual release of the active component, which explains the prolonged (long-term) effect of the drug. Only water was used as an auxiliary ingredient in the solution for parenteral administration.

Pharmacological properties

The therapeutic activity of the drug is due to the ability of its active ingredient to block receptors with increased sensitivity to histamine. After all, it is after this neurotransmitter enters the bloodstream that an allergic reaction begins to develop. After using the tablets, the signs of hypersensitivity subside after half an hour. After the injection, the antihistamine effect appears almost immediately.

At the same time, the production of leukotrienes is also inhibited, which explains the mild anti-inflammatory effect of the drug with:

• antiallergic;
• antiexudative;
• antipruritic therapeutic activity.

Spasmodic smooth muscle muscles relax, which causes the disappearance of painful and other uncomfortable sensations.

Pharmacodynamics and pharmacokinetics

After using the drug in any dosage form, there is a rapid and complete absorption of chloropyramine into the systemic circulation, including from the gastrointestinal tract. In the presence of food in the stomach, this process slows down somewhat. The almost completely active component of the drug forms complexes with plasma proteins.

Its biotransformation occurs in the hepatic structures with the participation of a number of enzymes with the formation of metabolites. The products of biochemical transformation are evacuated from the body mainly by the organs of the urinary system. Only a small part leaves it with feces.

Indications for use

The ability of the drug to dose-dependently suppress the release of histamine determines its wide field of application in allergological practice.

By doctors, he is included in the therapeutic schemes of patients with the following pathological conditions:

• hives;
• serum sickness;
• hay fever;
• rhinitis;
• conjunctivitis;
• anaphylactic reactions, regardless of their severity;
• angioedema;
• contact dermatitis;
• acute and chronic eczema;
• neurodermatosis;
• toxicoderma;
• signs of hypersensitivity caused by taking any pharmacological drugs;
• infectious lesions of the respiratory tract, proceeding with severe intoxication.

In the treatment of diseases with an allergic component, the drug is more often used for prophylactic purposes. Taking it in advance helps to prevent the release of mediators into the systemic circulation, to prevent the occurrence of discomfort.

Contraindications

The drug is not used in case of individual intolerance to the active substance or one of the auxiliary components.

The solution is not prescribed to patients with such diseases and pathological conditions:

• Glaucoma.
• Adenoma of the prostate.
• Disorders of urination.
• Recurrent bronchial asthma.
• Ulcerative lesions of the digestive system.

Injections are strictly prohibited if the patient is simultaneously taking drugs that block oxidoreductase, which deaminates monoamines, for the treatment of concomitant diseases.

Pills are not included by doctors in the treatment regimens of patients with pathologies:

• hypersensitivity to milk sugar and other excipients, as well as the active ingredient;
• hereditary lactase deficiency;
• recurrent bronchial asthma;
• glucose-galactose deficiency.

In pediatric practice, the solution is in demand from the month of life, tablets - from the age of 3.

Suprastin is not used for breastfeeding. This is also true for the period of pregnancy. Under medical supervision, treatment with an antihistamine should be carried out for the elderly, patients with functional hepatic, renal, cardiovascular insufficiency. The therapy with tablets of patients with pathological conditions, which are contraindications for the use of an injection solution, is performed with caution.

Features of the use of the drug during breastfeeding

Suprastin is not used for breastfeeding. The manufacturer did not provide evidence of its safety for this group of patients. If it is necessary to treat with this particular drug during lactation, breastfeeding should be discontinued.

It is allowed to renew it a few days after the end of therapy, when the organs and tissues are completely cleared of chloropyramine and its biotransformation products.

Why Suprastin causes drowsiness in a child who is on HB

The active substance of the drug is able to overcome all physiological barriers and accumulate in breast milk. Together with it, it sinks into the child's body, has an inhibitory effect on the central nervous system. A similar effect is manifested by drowsiness for several hours.

Instructions for use, dosage

It is strongly discouraged to use Suprastin during breastfeeding. But sometimes situations arise when it is impossible to do without urgent pills or an injection. With the sudden penetration of an allergic agent into the body, anaphylactic reactions develop with severe respiratory failure and other life-threatening conditions. In such cases, the use of the drug is necessary.

The doctor determines the optimal number of tablets or injection solution. When calculating doses, he must take into account the cause of the development of pathology, the nature and severity of symptoms. The doctor conducts treatment in minimal doses that are therapeutically significant, but safe for the child.

If an allergic reaction develops quickly, and there is no opportunity to get to a hospital, then you need to take a pill or inject 1 ml of solution into a muscle or vein. After medical attention has been provided, it is recommended to stop breastfeeding for a few days.

For allergies in a nursing mother

If a woman took an antihistamine before carrying a child, then this does not guarantee its safety during lactation. The absence of side effects in the past does not mean that they will not arise after delivery. During pregnancy, the body has undergone changes, including as a result of constant fluctuations in hormonal levels. And the deterioration in the well-being of the mother will certainly affect the child.

A single pill intake or injection is possible in emergency situations. Then the child's condition should be closely monitored over several days. If it is unsatisfactory, then you should immediately seek medical help.

For allergies in an infant

The use of an injection solution in the treatment of children after the first month of life is permissible, it is usually practiced for life-threatening conditions. This does not mean that the intake of chloropyramine in breast milk will not harm its health. Indeed, to relieve allergic symptoms in an adult, the drug is used in sufficiently high doses. This amount is quite enough to cause an overdose in a child.

Suprastin during breastfeeding is not used to relieve allergic reactions in children and due to the presence of auxiliary components in the composition. If the child has a hypersensitivity to one of them, then there is a high probability of anaphylactic shock. This is the name of an acute pathological condition characterized by severe hemodynamic disturbances and hypoxia.

Side effects

Failure to comply with the rules for the use of tablets and solution for parenteral administration may cause the development of adverse reactions.

They manifest themselves as follows:

• disorders of hematopoiesis: leukopenia, agranulocytosis, hemolytic anemia;
• anaphylactic signs of a local and systemic nature;
• drowsiness, loss of strength, dizziness, disorders of coordination of movements, psychoemotional instability, illusory movement of the body or others objects, trembling limbs, headache, muscle twitching, degeneration of neurons in the brain caused by disorders metabolism;
• visual disturbances, increased intraocular pressure;
• a drop in blood pressure, a heart rate of more than 90 beats per minute and other arrhythmias;
• abdominal pain and other uncomfortable sensations, dryness of the mucous membranes of the mouth, nausea, often leading to vomiting, diarrhea, constipation, suppression or increased appetite;
• primary lesions of muscle tissue;
• problems with urination, the formation of edema, difficulty in the flow of urine into the bladder;
• hypersensitivity of the skin to ultraviolet radiation.

Any of the above side effects requires urgent medical attention to replace the antihistamine and carry out symptomatic treatment.

Overdose

The development of an overdose is possible due to the use of tablets in an increased amount, frequent administration of an injection solution. The pathological condition is characterized by side symptoms, but only more intense.

And also such signs of excessive pharmacological activity of chloropyramine:

• hallucinations, anxiety, lethargy, seizures, pathological involuntary movements;
• persistently dilated pupils, overflow of blood vessels of the face, feverish conditions;
• coma, pronounced signs of a decrease in the functional activity of the cardiovascular apparatus, respiratory organs.

If possible, you need to quickly empty the stomach, and then seek medical help, since the risk of death is quite high. Therapy is symptomatic.

special instructions

The active substance of an antiallergic drug can have a negative effect on the functioning of the central nervous system. It is not recommended to drive vehicles during therapy. It is also inappropriate to perform work that requires a high speed of psychomotor reactions, increased concentration of attention.

Patients with severe renal and hepatic pathologies in some cases require dose adjustment downward. This is due to the distortion of the pharmacokinetic parameters of the active substance. Its biotransformation and evacuation proceed directly with the help of the hepatic and renal structures.

Drug interactions

Simultaneous administration of the drug with other drugs must be agreed with the doctor.

Its active component is capable of distorting the pharmacodynamic and pharmacokinetic parameters of such medicines:

• agents blocking oxidoreductase, deamination of monoamines;
• tranquilizers, sedative analgesics;
• muscarinic parasympatholytics;
• Atropine;
• tricyclic antidepressants.

When taken simultaneously, the effect of these funds can increase, provoking pronounced side effects. You can not take drugs that contain an identical active substance.

Analogs

If the patient is intolerant of the components of the drug, the use of analogues that have similar therapeutic properties is required. If hypersensitivity to an auxiliary component is detected, then structural substitutes are used that contain an identical active substance.

In case of individual intolerance to chloropyramine, active analogs are prescribed. They show similar therapeutic effects, but they are due to a different active substance.

Suprastin analog group	Names of medicines
Structural	Suprilamin, Histaprim
The operating	Claridol, Claritin, Pipolfen, Zyrtec, Tavegil

Suprastin is contraindicated for breastfeeding and it is forbidden to choose an analog on your own. Without basic knowledge of pharmacodynamics and pharmacokinetics, there is a high risk of purchasing an unsafe medicine. It is required to consult with the supervising physician.

More often, with HV, analogs are prescribed Hifenadine and Clemastine.

Terms, conditions of sale and storage

Store the drug at room temperature in a dark place. The shelf life is 5 years. The access of children to the storage area should be limited.

When buying pills, you do not need to show the doctor's prescription to the pharmacy employee. It is required for the purchase of an injection solution.

Price

The cost of an antihistamine varies in pharmacy chains, online drug stores. It will be possible to buy tablets for an average of 120 rubles, a solution for parenteral administration - for 130 rubles.

Despite the impressive list of potential side effects, Suprastin is relatively safe. They appear quite rarely and mainly when the dosage regimen is violated. But when breastfeeding, the use of tablets and parenteral solution is strictly prohibited.

Video about the drug Suprastin

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