Khilak Forte in drops. How to take, dosage for children, adults

Hilak Forte - German Probiotic metabolic type, designed to normalize the microbial composition of the intestine. Manufacturer - pharmaceutical company "Merkle". Good tolerance of the drug in drops and the almost complete absence of unwanted reactions allows infants, pregnant and lactating women to take it.

Release form

The drug is available in the form of drops for oral administration, which is a clear yellow-brown solution.

There are 2 types of packaging: vials with a volume of 30 and 100 ml, closed with screw caps and equipped with individual dosing droppers. The walls of the vials are made of dark glass, which protects the contents from exposure to sunlight.

There are 2 options for drops on sale: with a neutral taste and cherry.

Chemical composition

The active composition of the drug contains metabolites - waste products of 4 types of bacteria, inhabitants of the normal intestinal microflora:

• Escherichia coli (Escherichia coli) in the amount of 24.9 g;
• Enterococcus faecalis (fecal enterococcus) - 12.47 g;
• Lactobacillus acidophilus (acidophilic lactobacillus) - 12.47 g;
• Lactobacillus helveticus (lactobacillus helveticus) - 49.89 g.

The products are in the form of an aqueous substrate. The amount of substances is indicated per 100 ml of liquid.

As auxiliary ingredients, the composition of the drug includes:

• dipotassium phosphate, disodium phosphate heptahydrate, potassium sorbate (preservatives);
• lactic, phosphoric and citric acids (antioxidants and acidity regulators);
• sodium saccharinate and cyclamate (sweeteners);
• cream or cherry flavors;
• water.

The substrates contain lactose. Its amount does not exceed 70 mg per ml.

Pharmacological properties

Metabiotic Hilak Forte contains finished products of the vital activity of bacteria characteristic of normal intestinal microflora.

Among the beneficial metabolites of four bacteria are lactic acid and short chain fatty acids:

• oil;
• acetic;
• propionic.

They improve the quality of intestinal microecology by reducing the number of opportunistic bacteria. Thus, the normal microbial biogeocenosis is restored. Lactic acid changes the acidity of the intestine, thereby inhibiting the growth of pathogenic flora. Against this background, the process of absorption of nutrients and the production of vitamins B and K return to normal.

Fatty acid:

• start the regeneration of the damaged intestinal epithelium and reduce atrophic processes in it;
• reduce inflammation;
• increase local immunity.

Butyric acid promotes the absorption of excess fluid in the intestines, which thickens stools and prevents diarrhea.

It is advisable to take Khilak Forte in drops for enteritis caused by salmonella infection. The result of the action of metabolites is the growth of acidophilic anaerobic intestinal microflora, antagonistic to salmonella. The drug has shown its effectiveness in the treatment of dysentery, subject to specific antibiotic therapy.

Pharmacodynamics and pharmacokinetics

The drug begins to act immediately after entering the gastrointestinal tract. This is the advantage of Hilak Forte over other probiotic preparations containing bacteria: in order to activate and take root in the intestine, dried microorganisms need several hours.

Only after that, they begin to produce their metabolites, which ultimately establish the necessary microbial balance. Hilak Forte does not contain bacteria, but ready-made metabolites that do not need time to activate.

As you move through the intestines, the active substances of the drug suppress the growth of pathogenic microorganisms that provoke inflammation and digestive disorders. Enterococcus faecalis metabolites predominantly act in the lumen of the small intestine; for the production of other bacteria, the field of activity is the large intestine.

Bile and digestive enzymes do not act on metabolites, they are not destroyed in the acidic environment of the stomach.

Bringing detailed data on the kinetics of the drug is not possible, since the composition includes a variety of products of the vital activity of symbiotic bacteria. The fact that they are numerous makes it difficult to conduct appropriate pharmacokinetic studies.

Indications for use

Hilak Forte in the form of drops is recommended for the following conditions:

• intestinal dysbiosis caused by a change in the composition of the intestinal microflora as a result of prolonged therapy with antibiotics or sulfonamides;
• excessive gas formation, changes in the frequency and consistency of stools (diarrhea, constipation);
• maldigestion syndrome, that is, a violation of the digestion of food;
• inflammatory diseases of the gastrointestinal tract - gastroenteritis, non-ulcer colitis;
• atrophic processes in the stomach and small intestine, caused by age-related changes or long-term course - chronic gastroenteritis, gastritis with low acidity;
• diseases of the liver and gallbladder caused by pathogenic microflora that came with food contaminated with bacteria;
• atopic dermatitis, eczema, urticaria and other skin manifestations of allergies;
• recovery period after suffering salmonella enteritis;
• adaptation to unfamiliar food when changing the diet on travel, prevention of "traveler's diarrhea".

Contraindications

The product has a good safety profile and a short list of contraindications.

Hilak Forte drops should not be taken by people with a deficiency of the lactase enzyme and glucose intolerance. The use of the drug is excluded if hypersensitivity reactions were previously observed To any of the components.

Pregnancy and lactation are not contraindications.

At what age can the drug be used?

There are no age restrictions: the drug can be given to infants from the first days of life. With its help, the intestines are colonized with the necessary microflora, which reduces colic in babies. The use of a drug is practiced to accelerate the elimination of Salmonella at any age, including in infants.

Instructions for use, dosage

In accordance with the instructions, the drug should be taken 3 times a day. Best time to eat: just before meals or while eating.

Pre-shake the bottle, and dilute the required amount of solution with water.

Since the drip solution has an acidic pH, it causes the milk to curdle. For this reason, the drug should not be consumed with dairy products. To dilute it, juices, tea or compotes are acceptable.

Children and adults require different dosages of the drug. After the symptoms subside, it is possible to reduce the daily dose by 2 times.

For children

Single dose for infants: 15 to 30 drops. This amount is added to warm water or the juice that has already been introduced into complementary foods.

Older children are given 20 to 40 drops at a time.

Children are advised to offer the drug with a cherry flavor - it is easier for small patients to tolerate. A 30 ml package is enough for 6-9 days of admission, a large bottle - for 30-40 days.

Adults

Recommended single dose for an adult: 40 to 60 drops. A small bottle is enough for 4 days of treatment, a bottle of 100 ml - for 15 days of admission.

With heartburn and increased acidity of the stomach, the daily dose must be divided by 5-6 times.

Side effects

Hilak Forte drops should be taken in accordance with the prescribed dosages. In general, the drug is well tolerated; its side effects are minimal. Patients prone to allergic reactions may experience itching, skin rashes, and hives. In some cases, undesirable effects are manifested by constipation or diarrhea.

Overdose

In the instructions for the drug, the manufacturer notifies that no cases of overdose have been reported. If a large amount of the solution is accidentally swallowed, medical supervision is necessary.

special instructions

For acute diarrhea, drops are prescribed only along with plenty of drinking and other means of rehydration therapy. Compliance with this requirement is especially important in the treatment of infants.

If loose stools are accompanied by an increase in temperature, an admixture of mucus and blood in the feces, an acute infectious process is possible. In this case, it is necessary to consult a therapist to prescribe additional medications.

The solution does not contain alcohol. Its reception does not affect the speed of psychomotor reactions and does not reduce concentration. In this regard, during therapy, there is no need to limit activities that require these qualities. The tool does not reduce the ability to drive vehicles.

Drug interactions

You can not take the drug together with drugs that neutralize gastric acids - antacids (Maalox, Fosfalugel, Almagel, Gaviskon). Antacids interfere with the absorption of other substances, and have a neutralizing effect on lactic acid. If the need to take them still exists, the interval between medications should be at least 2 hours.

Analogs

Hilak Forte can be replaced with a number of drugs that have a similar effect on the gastrointestinal tract. Analogues have a common purpose of application: correction of disturbed intestinal microecology as a result of unfavorable factors.

The main purpose of such funds: prevention and treatment of dysbiosis, which is characterized by persistent violations of the quantitative and qualitative composition of microorganisms in the intestine. Other indications may be: diarrhea, intestinal infections, allergic skin diseases, gastrointestinal diseases. At the same time, doses, dosage regimens, contraindications and age restrictions may differ, since the active substances are also different.

The active composition of Hilak Forte is represented exclusively by the products of the enzymatic activity of bacteria. Among the analogues of the drug, there are no coincidences in the set of ingredients, but their list is compiled according to the presence of active metabolites of living bacteria in them and the general direction of action.

Aktoflor-S

The same principle of including not bacteria, but their metabolites in the composition, is the basis for the preparation Aktoflor-S (Grotex, RF). The product is based on 12 active compounds, which are analogs of the metabolites of symbiotic bacteria.

As in Hilak Forte, their combined action is aimed at restoring normal intestinal biocenosis by stimulating its own microflora. In addition, the drug is positioned as an additional source of essential amino acids. The tool is used for dysbiosis, helps to eliminate intestinal disorders and restore local immunity. Unlike Hilak Forte, it is intended for use exclusively by adults.

It is produced in the form of a solution poured into dropper tubes. The cost of a package consisting of 30 tubes is 460 rubles. and higher.

Normoflorin-D

The drug from the Russian manufacturer "Bifilux"; is available in the form of a solution for oral administration. Its purpose: the fight against dysbiosis and intestinal infections. Contains bifidobacteria and lactobacilli, as well as products of their enzymatic activity - metabolites.

To accelerate the growth of beneficial microflora, the prebiotic lactitol has been added, which serves as a breeding ground for lactic acid bacteria. The biocomplex inhibits the growth of pathogenic bacteria, restores mucous membranes and enhances local immunity.

The tool is recommended for use during antibiotic therapy, starting from the first day. But, unlike Hilak Forte, taking Normoflorin requires a 2-4 hour interval between probiotic and antibiotic.

The acidity of the solution is less pronounced than that of Hilak Forte, so the drug can be safely used in the presence of erosive and ulcerative lesions of the gastrointestinal mucosa. The tool is used in adults and children from 6 months. Release form - oral solution. A 100 ml bottle costs 220-250 rubles.

Biovestin

The drug is a probiotic emulsion containing live bifidobacteria and their metabolic products. Manufacturer: Bio-Vesta, Russia. Biovestin restores disturbed intestinal microflora in case of intestinal disorders, respiratory infections, food allergies, after taking antibiotics. The emulsion is not taken with food, like Hilak Forte, but 1 hour before or 1 hour after, with water or milk. The drug is approved for children under 1 year old.

One package contains 12 glass bottles with a solution. The daily dose for an adult is 1 bottle, for a child - from a quarter to a half bottle. Price - from 1400 rubles. per packing.

Bactistatin

These are capsules containing 3 active ingredients:

• metabolites of the bacterium Bacillus subtilis;
• zeolite is a natural enterosorbent;
• hydrolyzed soy proteins that act as a prebiotic.

The set of metabolites includes:

• lysozymes;
• bacteriocins;
• various enzymes;
• amino acids;
• catalase.

These substances are responsible for the suppression of opportunistic microorganisms and have immunomodulatory properties. Zeolite selectively binds bacteria and the toxins they release, as well as viruses, harmful substances, excess cholesterol and bilirubin. Due to the soy oligosaccharide, the prebiotic component provides better growth of bifidobacteria inhabiting the large intestine.

Like analog drugs, the remedy is recommended for intestinal infections, poisoning and various kinds of dysbacteriosis, including those resulting from antibiotic therapy. The drug improves skin condition in case of allergic dermatitis and acne. Due to its ability to bind excess bile pigment and cholesterol, Bactistatin is used in the complex treatment of liver and gallbladder diseases.

The capsules are drunk 2 times a day. A single dose for children over 6 years old - 1 capsule, for adults - 2 capsules. The package of the drug is enough for a month; its cost - from 711 rubles. Unlike Hilak Forte, the described analogs are not drugs. All of them have the status of biologically active food additives.

Terms, conditions of sale and storage

The drug is stored at room temperature not higher than +25 ° C away from heat sources, avoiding direct sunlight.

Hilak Forte drops should not be taken if its expiration date has expired. If stored properly, the medicine retains its therapeutic properties for 4 years from the date of manufacture. After opening the drug, the shelf life is reduced to 4 weeks.

The medicine is available over the counter without a prescription.

Price

The cost of the drug depends on the volume of the bottle, the release option and the region of sale. The specific price can be found in the pharmacy nearest to the place of residence. The table compares drug prices in several Russian cities.

Forms of issue
100 ml	100 ml, cherry flavor	30 ml	30 ml, cherry flavor
Prices in Moscow
581 r	569 r	RUB 318	320 RUB
In St. Petersburg
586 r	575 r	322 r	325 RUB
In Saratov
RUB 600	588 r	335 RUB	338 r

The safety and effectiveness of Hilaka Forte allows for the prevention and correction of violations intestinal microflora in a wide range of patients, and the release form - drops, makes its reception as much as possible convenient.

Video about the drug Hilak Forte

Description and instructions for drops Hilak forte: