Fluoxetine analogs without prescription. Price, reviews

Fluoxetine is a drugused in the treatment of depressive conditions caused by various factors. The drug is dispensed by prescription and has several over-the-counter similar products.

The medicine is manufactured in Russia in the form of capsules for oral administration. The active ingredient is fluoxetine (in the form of hydrochloride). The medication belongs to the group of antidepressants.

Indications:

• depression, which has a different nature of origin;
• obsessive compulsive disorder;
• neurosis (bulimic form of disorder).

The medicine is used only on the recommendation of a specialist. Reception rules: 20 mg 1 time per day. Apply the medicine according to this scheme for 1 month. Then the dosage is changed (upward) and taken 2-3 times a day. The duration of therapy is individual, according to the recommendations of the attending physician. The maximum daily dosage should not exceed 80 mg.

Domestic and imported counterparts of the product that can be bought without a prescription

Similar drugs are used in cases where the main agent is poorly tolerated and causes an allergy in the patient. Similar medicines are recommended to be used only according to the testimony of a specialist and under his supervision.

The doctor should also prescribe a generic drug, taking into account the patient's condition, the form of the established disease and other physiological characteristics.

The listed funds can be purchased without a prescription, however, before taking them, it is recommended that you first consult with a specialist or pharmacist.

St. John's wort pills

This product is produced in France in the form of tablets for oral use. He, in contrast to the original drug, has another active substance of plant origin - dry extract of St. John's wort.

Both drugs belong to different pharmacological groups, but they completely coincide in their effect. The substitute has a pronounced antidepressant and anxiolytic activity.

The very mechanism of action of medications is different. The funds have similar indications for use.

Thus, the analogue is recommended to be used in the following cases:

• disorders of a psychovegetative nature of origin (lack of mood, apathy);
• neurotic conditions.

Directions for use: 1-2 tablets 3 times a day. Duration of admission is at least 21 days. Without the advice of a specialist, the duration of therapy should not exceed 3 months.

If necessary and only with the permission of a doctor, treatment can be extended. In this case, the duration of admission in each case is determined individually, based on the clinical picture and the patient's condition.

Medicines have various contraindications. At the same time, the list of negative reactions in the original medicine is much wider and they occur more often. The substitute is not used in case of poor tolerance of the components (allergies) and in children under 12 years of age.

The main tool is not used in pediatric practice, since such studies on its safety of use have not been carried out in this period of time.

The main remedy is completely contraindicated for use during pregnancy and breastfeeding. Such studies have not been conducted with the generic drug, but it is also not recommended to use it in these cases.

Both medicines should not be used in conjunction with MAO inhibitors. In this case, the interval between the use of funds in both cases should be at least 2 weeks.

Since drugs are psychostimulants, it is not recommended to engage in potentially hazardous activities or drive a car during the period of their use.

While taking the analogue, it is necessary to avoid prolonged exposure to the open sun or other ultraviolet radiation. The original drug does not have such restrictions.

The most preferred remedy for moderate to severe depression is the main remedy. For mild depressive conditions, it is recommended to take a substitute. Both medications do an excellent job and help to quickly cope with negative symptoms caused by depression.

The effectiveness of both the main agent and the substitute is high. At the same time, the advantage of the generic drug is the possibility of its use in elderly patients, with renal and hepatic functional disorders, which significantly expands the scope of its use and group patients.

The analogue is well tolerated and rarely causes the development of negative reactions. In original capsules, such effects occur much more often.

The advantage of the substitute is over-the-counter sale. However, the cost of the original drug is significantly lower, which makes it more affordable for most of the population.

Fluoxetine and over-the-counter analogues also require prior consultation with a specialist, since most of the drugs have anxiolytic properties and sedatives.

Apo-Fluoxetine

Unlike the main drug, this substitute is manufactured in Canada in the form of oral capsules. The medicines have an identical active substance (fluoxetine hydrochloride).

Medicines belong to the same pharmacological group (antidepressants) and have absolutely identical indications for use. In this case, the mechanism of action is the same for them, since the drugs are the same in chemical composition.

Dosage regimen: at the beginning of therapy, take 20 mg 1 time per day (take capsules in the morning). If necessary, a single dosage may be increased. However, increasing the dose is possible only after 3-4 weeks of using the drug. Moreover, the maximum daily intake should not exceed 80 mg. The duration of therapy in each case is determined individually by the attending physician. The drugs have the same adverse reactions.

For both funds, the following manifestations are characteristic:

• Central nervous system: body tremors, anxiety, increased drowsiness, migraines, sleep disorders.
• Digestive disorders: nausea, diarrhea.
• Metabolic processes: hyperhidrosis, low blood sugar, low sodium levels (in elderly patients).
• Reproductive organs: decreased sex drive.
• Allergy signs: rashes, itching.
• Other reactions: soreness in the area of ​​muscles and joints, difficulty breathing, an increase in body temperature.

The frequency of occurrence of these symptoms in both cases is approximately the same and depends on the physiology of a particular patient.

Medicines have absolutely identical contraindications, including children's age and the period of gestation and feeding of the child.

General restrictions on use:

• glaucoma;
• atonic disorders (in the area of ​​the bladder);
• hyperplasia of the prostate (benign form of the disease);
• functional disorders of the kidneys, proceeding in severe form;
• the combined use of drugs with MAO inhibitors (including a 2-week period after their cancellation);
• convulsions of a different nature of origin and mechanism of occurrence;
• epileptic seizures;
• intolerance to the components;
• pregnancy and breastfeeding.

Both drugs require a temporary refusal (for the entire period of therapy) from driving and carrying out potentially hazardous activities, as they can have a negative impact on the mental human condition.

Medicines have identical interactions with other medicines, which should be taken into account when replacing them.

The effectiveness and therapeutic effect of the capsules in both cases is approximately the same. The products help to cope with the signs of disorders in a short time and rarely cause allergies or other negative reactions. Medication should only be taken on the advice and guidance of a physician. Fluoxetine and over-the-counter analogues should be taken when there are certain indications and only after an accurate diagnosis has been made.

Prozac

Prozac, an over-the-counter substitute for Fluoxetine, is manufactured in Switzerland as capsules for oral use. The main agent and this analogue have an identical chemical composition (active component).

Both drugs belong to the same drug group and have the same field of application:

• depressive conditions, which have a different mechanism of occurrence;
• bulimia caused by psychological factors;
• obsessive-compulsive disorders.

Dosage regimen: during the first 3-4 weeks, 20 mg of the drug is prescribed once a day. Then the dosage is increased (in each case it is calculated individually). Thus, it is taken from 2 to 3 times a day.

The duration of the course is set by the attending physician in each case separately. This takes into account the severity of the disorder and other physiological characteristics of the patient. The maximum daily dose of the drug should not exceed 80 mg.

Both medicines are prohibited for use during pregnancy and breastfeeding, since the active substance can have a negative effect on these conditions. The funds also have the same contraindications, including children's age. In pediatric practice, such drugs are not used.

Medicines have the same adverse reactions. The frequency of their development and the severity depends on the individual characteristics of the patient's body. According to the studies conducted, in both drugs, they occurred extremely rarely and in approximately the same number of patients.

Fluoxetine and over-the-counter analogues are not recommended to be taken for a long time without consulting a doctor, since in some cases such drugs can lead to the development of addiction. Both the original drug and its substitute can lead to drug interactions with identical groups of drugs.

Interaction is possible:

• Drugs that inhibit the work of the central nervous system and alcohol - an increase in the inhibitory effect.
• MAO inhibitors, furazolidone, procarbazine, tryptophan - the so-called serotonin syndrome can occur.
• Tricyclic and tetracyclic antidepressants, trazodone, carbamazepine, diazepam, metoprolol, terfenadine, phenytoin - an increase in the therapeutic effect and an increase in the risk of adverse reactions.
• Hypoglycemic drugs - enhancing their action.
• Warfarin - increasing its effects.
• Phenylpropanolamine - increased activity, development of dizziness, weight loss (only 1 similar case was registered).
• Digoxin is an increase in the level of the components of this drug.
• Antipsychotics, antipsychotics - the development of extrapyramidal and dystonic disorders.
• Drugs that affect liver enzymes - inhibition of transformation processes in the body.
• Dextromethorphan - the occurrence of hallucinations (a single case was registered).
• Lithium salts - an increase or decrease in the level of lithium in the blood.
• Imipramine and desipramine - a significant increase in their concentration in the blood.
• Propafol - uncontrolled movements (only 1 case was observed).
• Flecainide, mexiletine, propafenone, thioridazine, zuclopenthixol - increasing their effects.

For the entire period of taking the capsules in both cases, you should refuse to drive and perform other potentially hazardous types of work, since the funds can have a negative impact on the human psyche.

Medicines have shown high efficacy in research and can be used interchangeably. However, the treatment must be carried out to the end with one of the selected drugs.

A significant disadvantage of generic drugs is their higher cost. In this case, the therapeutic effect of the agent is identical to that of the original capsules.

List of other structural analogues of the drug, substitutes in composition, mechanism of action

Fluoxetine and over-the-counter analogs should be taken strictly as directed by your doctor or as directed by each drug.

At the moment, other drugs are being produced that have a similar effect or recommendations for prescription. These funds should also and can be used only as directed by the attending specialist.

Classification by active substance (all products have absolutely identical indications for use):

• Profluzak (Russia) - capsules.

  

• Portal (Slovenia) - capsules.
• Prodep (India) - capsules.
• Fluval (Slovenia) - capsules.
• Flunesan (Serbia) - tablets.
• Fluoxetine-OBL (Russia) - capsules.

List of medicines by pharmacological group (the list of medicines includes more than 100 items):

• Azafen (Russia) - tablets.
• Amitriptyline (Russia) - solution for intramuscular administration.
• Brintellix (Denmark) - tablets.
• Zoloft (USA, Germany, Italy) - tablets.
• Imipramine (Russia) - dragee.
• Mirzaten (Slovenia) - tablets.
• Oprah (Russia, Iceland, Germany) - tablets.
• Paroxetine (Russia, Macedonia) - tablets.
• Selektra (Switzerland) - tablets.
• Simbalta (Switzerland) - capsules.
• Tsipralex (Denmark) - tablets.
• Elitsea (Russia) - tablets.

List of the cheapest medicines:

• Amitriptyline (Russia) is a solution for intramuscular injections. The drug has a more pronounced hypnotic (sedative) effect.
• Phenazepam (Russia) - tablets. Refers to a group of tranquilizers.
• Sibazon (Russia) - solution for intramuscular or intravenous administration. It has a pronounced anxiolytic effect.
• Valerian extract (Russia) is a sedative with a calming effect.
• Motherwort tincture (Russia) is a sedative of plant origin.
• St. John's wort (Russia) is an anxiolytic of natural origin.
• Validol (Russia) - tablets used for neuroses and cardialgia.

OTC generics:

• Doppelgerz Neurotonic (Germany) is an elixir intended for oral administration.
• Negrustin (Germany) - oral solution.
• Gelarium (Germany) - dragee.
• Persen (Slovenia) - tablets.
• Dobrokam (Russia) - tablets.
• Novo-Passit (Czech Republic) - tablets, oral solution.
• Afobazol (Russia) - tablets.
• Tenoten (Russia) - lozenges.

It should be borne in mind that all synthetic antidepressants are dispensed strictly by prescription, since most of them contain opioid and other unsafe components. This requires mandatory monitoring of the dynamics and strict control of dosages.

OTC medicines are made on the basis of herbal ingredients and belong to the class of phyto-drugs or homeopathic remedies that are relatively safe and do not require strict control by the treating person specialist.

Prices

The cost of medicines depends on the region and region of their sale and the pharmacy trade network.

Prices for the main remedy in pharmacies in Moscow and the Moscow region vary between 50-80 rubles.

Name of the drug	Price
St. John's wort (tablets)	RUB 75-340
Apo-Fluoxetine	RUB 60-300
Prozac	RUB 455-540

Before using Fluoxetine or its substitutes, it is necessary to read the instructions for their use and consult a specialist. You can find out the availability of the original drug or its OTC counterparts, as well as find out their price at any nearby pharmacy located at the place of residence.

Video about the drug Prozac

Fluoxetine (Prozac) - action, indications: