Controlok 20-40 mg. Price, instructions for use, reviews

Controlok is antiulcer medication with pronounced properties, which is actively used to treat patients with various diseases of the digestive system. The agent in a dosage of 20 or 40 mg is used with the same frequency, but in each case, you can choose the optimal rate for the patient. The price of the drug is affordable for patients, but sometimes they prefer to choose analogs that are cheaper.

Composition and form of release

The drug can be found in pharmacies in the form of tablets and lyophilisate to obtain a solution that is administered parenterally. The tablets are small and biconvex, enteric coated. The medicine is packaged in standard blisters of 5 or 7 pieces, placed in cardboard boxes of 1-4 pieces. Blisters of 14 tablets are also available.

There are 1 or 2 such plates in a box. A description is attached to the blisters, indicating the features of the application. The lyophilisate is placed in clear glass vials. Each bottle can be placed in an individual cardboard box. Manufacturers also produce boxes of 5-10 bottles. A description is also attached to the bottles.

The lyophilisate is a white or almost white powdery mass. After adding sodium chloride, it dissolves, the resulting solution may have a precipitate and a yellowish tint.

The composition of the tablets and lyophilisate contains the component pantoprazole, which has the main therapeutic effect. The tablets additionally contain talc, starch, silicon dioxide. The lyophilisate contains no excipients.

The amount of active substance in the composition of the tablets can be 20 or 40 mg. 1 bottle of lyophilisate usually contains 40 mg of pantoprazole.

Terms of sale and prices

Controloc 40 mg and a different dosage can be purchased from different pharmacies without a prescription when it comes to tablets. The lyophilisate is purchased after presentation of the prescription form. The price of the product ranges from 300-560 rubles.

The cost of the drug differs depending on the amount in the package, the region of distribution.

Pharmacological properties

The drug belongs to the group of proton pump inhibitors, therefore it has pronounced antiulcer properties. The medication helps to improve the condition in case of damage to the mucous membrane of the stomach, intestines.

The medicine prevents the progression of pathologies of the pancreas, liver, small and large intestines. The medication reduces the acidity of gastric juice, combats the symptoms that accompany many pathologies of the stomach.

The complex effect of the drug on the patient's body helps to prevent the development of complications against the background of the progression of pathologies.

Pharmacodynamics and pharmacokinetics

After oral administration or parenteral administration of the drug, the main ingredient of the composition is concentrated in the affected area and has a therapeutic effect. Pantoprazole reduces the acidity of gastric juice, which allows you to get rid of heartburn, pain in the stomach that occurs against the background of damage to the mucous membranes.

The drug also has other properties:

• Prevents further damage to the tissues of the digestive tract by reducing the production of hydrochloric acid. After the end of therapy, the effect lasts for several weeks.
• It has a positive effect on the basal stage of gastric juice formation, which makes it possible to normalize digestion in patients with gastritis and other stomach diseases.
• A decrease in the level of hydrochloric acid leads to an intensive formation of gastrin, which has a positive effect on the mucous membranes and leads to their gradual recovery.
• The medicine creates a kind of protective film on the surface of the mucous membranes, which prevents further damage to tissues by food or its own hydrochloric acid.

With oral administration, the therapeutic effect develops within 40-50 minutes, but the most pronounced effect is noted after 4 hours. With parenteral infusion, this period is somewhat reduced. The maximum concentration of ingredients in the blood is reached within 1-2 hours after taking a single therapeutic dose. The medicine has no effect on the motility of the digestive tract.

The metabolism of the components is carried out in the patient's liver by about 80%. The decay products of pantoprazole are excreted by the kidneys and intestines within 24 hours after taking the last dose. In some patients, the period of cleansing the body is somewhat extended if there are abnormalities in the intestines and kidneys in the anamnesis.

The accumulation of ingredients in the blood or tissues does not occur, which makes it possible to somewhat reduce the likelihood of an overdose, but not exclude it.

Indications for use

Controlok 20 mg, the price of which is usually affordable, as well as a remedy in a different dose, is prescribed to patients with various diseases of the digestive system.

Main indications for use:

• Gastritis with increased acidity of gastric juice, accompanied by frequent pain in the stomach. The drug is prescribed in the acute stage and in the chronic course of the pathological condition with regular exacerbations.
• Peptic ulcer of the stomach and duodenum at different stages. Usually, the drug is prescribed in case of exacerbation of symptoms, but it is often taken as prophylactic courses to prevent exacerbations.
• Reflux esophagitis, in which the patient is often worried about heartburn as a result of the reflux of stomach contents into the esophagus.
• The defeat of the stomach as a result of the multiplication of the bacteria Helicobacter pylori. The medicine does not help kill the bacterium, but it relieves the accompanying symptoms that occur when it multiplies on the mucous membranes.
• Chronic pancreatitis. The drug is prescribed in combination with other drugs to improve the effectiveness of treatment.
• Bowel diseases of inflammatory origin, developing against the background of gastric lesions.

The medication is often used in combination with other medications in the treatment of pathologies of the liver, gallbladder, if the doctor considers it appropriate.

Contraindications

Despite the effectiveness of the product, its use is not allowed when diagnosing intolerance to any of the ingredients of the composition.

Other complications include the following conditions:

• Gastritis with low acidity of gastric juice. Taking the drug in such patients provokes complications and aggravation of symptoms.
• Dyspeptic disorders of neurotic origin are not treated with the drug, since they require the use of medications with other properties.
• The period of childbearing and breastfeeding. To date, there is not enough research on the effect of the ingredients of the composition on the body of the mother and child, therefore, if necessary, other means are selected for patients.
• The patient's age is up to 18 years. For children, if necessary, safer means are selected.
• Internal bleeding as a result of perforation of the walls of the digestive tract.
• A state of shock against the background of injuries or poisoning.
• Impaired consciousness.

With caution, the drug is prescribed during the recovery period after suffering a myocardial infarction or ischemic stroke, but the decision in each case is made by the doctor. It is possible to identify individual contraindications during the examination.

Methods of administration and dosage

Controlok 40 mg (the price of the product depends on the amount in the package) and the drug in a lower dosage is prescribed patients according to a certain scheme, which may differ depending on the disease and the degree of its neglect.

With gastritis with high acidity of gastric juice

In case of damage to the mucous membranes of the stomach, the drug is used in courses of 2-3 weeks with daily pills in the morning and evening. With a mild and severe form of pathology, the drug in the form of a lyophilisate is not used, since the tablet form brings a pronounced result.

A single dosage for a patient is 20 mg. Do not exceed it or use the drug more often than the doctor prescribes. If necessary, it is allowed to extend the course according to individual indications.

With peptic ulcer

When a peptic ulcer is diagnosed, patients may be prescribed tablets or a lyophilisate to prepare a solution. The specific dosage form depends on the patient's condition. If the course of the disease is mild, it is enough to take 3 tablets of 20 mg per day at approximately equal time intervals.

In a severe form of a pathological condition, procedures are prescribed with a drip or intravenous jet infusion of the drug. For jet injection, it is necessary to dissolve the powder from 1 bottle in 20 ml of sodium chloride 0.9%. After that, the resulting agent is injected slowly, observing all standard recommendations. Usually, parenteral administration is carried out in a hospital, but outpatient treatment is allowed if the patient does not have severe symptoms and complications.

If necessary, drip infusion of the drug, 1 bottle of lyophilisate falls on 100-200 ml of sodium chloride. The procedure is carried out only in a hospital, especially if the patient has concomitant deviations from other parts of the digestive system. The infusion is carried out 1 time per day, the duration of the course for parenteral administration usually does not exceed 2 weeks. Prolongation of treatment is possible according to indications, but usually, if necessary, a long course of the patient is transferred to a tablet dosage form.

With reflux esophagitis

Controloc 40 mg (the price of tablets may be slightly lower than the cost of a lyophilisate) is used to identify symptoms of reflux esophagitis. Usually, patients are not prescribed a solution, but at one time they may recommend taking 40 mg of the drug, that is, 2 tablets of 20 mg each.

The duration of therapy for a pathological condition is approximately 2 weeks. Often, courses are carried out regularly, every 3-6 months, depending on the symptoms and the presence of concomitant deviations.

Sometimes the medication is used to prevent an increase in gastric acidity, for example, during therapy with non-steroidal anti-inflammatory drugs. The dosage for the patient is 20 mg, and the tablet is taken in the morning on an empty stomach. This scheme helps to prevent the development of complications and protects the gastric mucous membranes from the negative effects of medications.

Side effects

Violation of the instructions will certainly provoke the development of complications. They can affect the work of internal organs and systems, manifest in an acute or subacute form.

Damage area	Frequent negative reactions
Nervous system	From the side of the nervous system, complications manifest themselves in the form of dizziness and headache, weakness and fatigue. During the course of therapy, patients may be disturbed by irritability and insomnia, their performance decreases.
Digestive tract	Digestive disorders can occur even if all recommendations are followed. Patients report flatulence and bloating, nausea and bouts of vomiting, pain in the stomach or intestines. Symptoms are aggravated by continuing to take the medication. Experts note that the use of tablets often leads to the development of complications from the digestive system.
Musculoskeletal system	Muscle pains bother patients often, especially if they have a history of pathology of the musculoskeletal system. Often, discomfort in the joint area is added to the symptoms, which increases with movement and intense physical exertion.
Respiratory system	If a patient has a history of chronic respiratory pathologies, complications from the respiratory system may develop in the form of coughing, shortness of breath during exercise or at rest.
Skin	An allergy to any form of medication manifests itself in the form of a rash on the skin, itching and burning of tissues. With continued use of the medication, the rash spreads over large areas, and the itching and irritation increase.

The appearance of negative reactions is considered a reason for visiting a doctor. The specialist may not cancel the treatment, but will adjust the dosage. It is strongly discouraged to treat complications on your own, as well as ignore them for a long period, while continuing to take pills.

Overdose

Controloc 20 mg (the price of the drug may be higher when purchasing a large package) usually does not provoke an overdose when taken at the dose prescribed by the doctor for a certain period of time. Lyophilisate also does not provoke such complications, since it is administered in an acceptable dose and for a short period of time.

However, taking a large number of tablets once leads to an aggravation of the condition and the appearance of additional complications. Patients report repeated vomiting during the day and loose stools, pain in the abdomen.

Overdose may be accompanied by complications from the nervous system in the form of weakness and dizziness, hallucinations. The condition worsens with the development of convulsive syndrome, which in most cases is the result of the loss of a large amount of fluid with vomit and feces.

Symptoms of an overdose cannot be ignored, nor can the medication be used on your own. If manifestations appear, you should immediately consult a doctor.

special instructions

It is important to take the medication in tablet form as a whole. Do not grind, split or chew it before swallowing. Otherwise, the effectiveness of therapy is somewhat reduced, the process of absorption of components in the intestine is disrupted.

Lyophilisate should be used only according to indications and in a medical institution. You should not inject the medicine yourself at home, even if you follow the dilution rules.

Drug interactions

The medicine is not used simultaneously with medicines containing the same active ingredient. With caution, the medication is used in combination with antacids, since the effectiveness is somewhat reduced. If the use of such a medicine is required, it is necessary to take a break of at least 2 hours.

In combination with non-steroidal anti-inflammatory drugs, the drug is allowed to be used, but it is important to observe the time interval. If you need to use several drugs, it is important to visit a doctor in advance, who will determine the appropriateness of use.

Analogs

The drug has substitutes, which, if necessary, can be prescribed if the original is contraindicated for various reasons.

The most affordable substitutes are:

• Pantoprazole is considered the most popular analogue with the same active ingredient in the composition. The drug is available in several forms for oral administration and parenteral administration. The drug can be used in short and long courses, depending on the symptomatology of the pathology.
• Omez also refers to analogs, despite a different ingredient in the composition. The action of the drug is carried out due to the presence in the composition of omeprazole, which also belongs to the proton pump inhibitors. The drug is prescribed for gastritis with high acidity of gastric juice and peptic ulcer disease. Available in the form of tablets and lyophilisate.

Analogues are used only as directed by a doctor; you should not select them yourself.

Storage conditions and periods

It is necessary to store the medication for 3 years. The production date is indicated on the packaging, it is worthwhile to study the information before using.

Controlok in a dosage of 20 or 40 mg is prescribed to patients with various diseases of the digestive system. The price of the product is affordable, but if you purchase a large package, it can be higher. Despite this, the medicine is often used, as it is very effective.

Video about the analogue of Controlok

Stomach nipple: