Pharmazoline nasal drops. Price, instructions for use, reviews

Pharmazolin is a drugintended for topical use. Nasal drops can be purchased at an affordable price. The drug has a number of structural analogs. The application should be carried out according to the instructions.

Composition and form of release

Pharmazolin - nasal drops (the price of the drug is quite acceptable), making breathing easier. The drug is marketed in the form of a colorless transparent solution poured into 5 ml or 10 ml plastic bottles. The active ingredient is xylometazoline hydrochloride (no more than 1 mg).

Additional components may vary depending on the manufacturer:

• water for injections;
• E 386;
• sodium salt of ethylenediaminetetraacetic acid;
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• decamethylenedimethylmethoxycarbonylmethylammonium dichloride;
• sodium phosphate aqueous;
• disubstituted sodium phosphate.

The vials are sold in cardboard boxes. Each package contains an annotation.

Terms of sale, prices

The drug does not require a prescription from pharmacies. The purchaser does not have to present the form to the pharmacist. The cost of the drug is 45-70 rubles. Children's Pharmazolin may cost more than an adult.

Pharmacological properties

Pharmazolin - drops in the nose (the price of the drug is low), relieving swelling. Alpha-adrenergic agonist has a vasoconstrictor effect.

Pharmacodynamics and pharmacokinetics

The drug acts on alpha-adrenergic receptors. Drops help to narrow the capillaries, relieve swelling, and facilitate nasal breathing. Patients are well tolerated, complaints of side effects from patients suffering from hypersensitivity are rare. The drug does not suppress mucociliary function.

The composition of the drug contains components that have a moisturizing effect. Thanks to them, dryness and irritation of the mucous membrane is eliminated. The pH values ​​of the medication are balanced.

Pharmazoline belongs to the category of nasal anticongestants. Drugs in this category are responsible for eliminating nasal congestion. Their principle of action is based on the ability to reduce hypersecretion. Pharmazoline not only relieves the symptoms of a common cold, but also prevents the development of complications such as otitis media, eustachitis, sinusitis.

With systematic use, there is a normalization of sinus drainage. The risk of developing obstruction of the auditory tubes is reduced. The active ingredient is considered to be an imidazoline derivative. The component is characterized by a sympathomimetic effect. As a result of the activation of adrenergic receptors when the drug is instilled nasally, the vessels of the nose narrow. The hyperemia decreases, the edema is removed after 10-15 minutes.

According to reviews, nasal breathing is restored almost immediately after application. Xylometazoline is considered a medium-acting anticongestant. The therapeutic effect lasts for 2-10 hours. The active substance does not penetrate into the systemic circulation, it does not overcome the blood-brain barrier, and is not found in breast milk. The drug can be used locally. Absorption in this case is not observed.

Indications for use

Pharmazoline - nasal drops (the price may vary depending on the manufacturer), which are prescribed for respiratory diseases.

The main indications for use:

• the period of preparation of the patient for rhinoscopy;
• otitis media;
• sinusitis;
• acute allergic rhinitis;
• ARI.

You can use drops nasally for diseases of the sinuses. The drug accelerates the evacuation of mucus. The period of childbearing and breastfeeding cannot be considered an absolute contraindication. If a woman is not prone to allergic reactions, then the use of the drug in therapeutic doses is appropriate.

Contraindications

Like most drugs, nasal drops have a number of contraindications.

These include:

• simultaneous use of MAO inhibitors and xylometazoline;
• rhinitis of the atrophic type;
• craniotomy, severe TBI (history);
• endonasal transsphenoidal removal of hypertension;
• hyperthyroidism;
• glaucoma;
• pathology of the cardiovascular system.

Also, an absolute contraindication can be considered an individual intolerance to xylometazoline or additional components in the composition of the drug.

Method of administration and dosage

Pharmazolin - nasal drops (the price of a medicine for children may slightly exceed the cost of a medicine for adults), which are well tolerated by patients. The bottle goes on sale hermetically sealed. Before the first use, a hole must be made in the container. There is a sharp spike on the inside of the lid. With its help, the container is pierced.

There are 2 forms of the drug: children and adults. Pharmazoline 0.05% can be instilled in children under 12 years of age.

Instructions for use:

• up to 5 years - 1 drop in each nostril 2-3 times a day;
• 5-12 years old - 1-2 drops in each nostril up to 3 times a day.

It is strictly forbidden to independently increase the therapeutic rate. The appearance of any ailments in children during the use of the drug requires its immediate withdrawal.

Before rhinoscopy

Pharmazoline is prescribed to patients before rhinoscopy. Vasoconstrictor drops are responsible for restoring breathing and eliminating congestion. Their use is possible only in the absence of contraindications. If the patient has suspicions of glaucoma, hyperthyroidism, atrophic rhinitis and diseases of the cardiovascular system, then the specialist prescribes a number of additional examinations.

The dosage regimen of the drug directly depends on the age of the patient and the type of procedure. With anterior rhinoscopy, 2 drops of the solution should be instilled into each nostril for an adult. After 5-7 minutes. the doctor inserts a dilator into the nose and proceeds to the examination. The therapeutic dose of the drug for children is 1-2 drops.

If a posterior rhinoscopy is planned (especially if there is nasopharyngeal edema), an adult patient is instilled 2-3 drops of a vasoconstrictor drug. After 3-5 minutes. you need to treat the cavity with an anesthetic solution. Children are instilled 1-2 drops, the procedure is carried out under general anesthesia.

Acute otitis media

The disease often occurs against the background of the penetration of infection into the human body. Pathology is characterized by acute pain, temperature jumps, the appearance of purulent and bloody discharge. As otitis media develops, the nasopharynx swells, patients complain of hearing loss.

Pharmazoline can be included in drug therapy for ear canal inflammation. The drug is injected into the nostrils just before flushing or purging the passage. The therapeutic norm is no more than 4-4 drops for adults, for children - 1-2 drops.

Sinusitis

The disease is accompanied by inflammation of the paranasal sinuses. Allocate sinusitis of allergic, fungal, bacterial or viral etiology. Patients often complain of severe pain in the area of ​​the nodules of the eyes, bridge of the nose and temples. Body temperature rises to subfebrile values. The mucous discharge is replaced by purulent. The sense of smell disappears almost immediately.

The treatment regimen in this case should be selected individually. The dosage regimen is determined depending on the age of the patient and the severity of the sinusitis. Adult patients need to instill 2-3 drops of the solution into each nostril 2-3 times a day. For children under 6 years old, 1 drop of the drug is instilled 1-2 times a day.

Allergic rhinitis

Rhinitis of this type often occurs in people prone to allergic reactions. Pathology often develops in the spring or early summer. The disease is usually diagnosed in children (under 18). Rhinitis of the allergic type is manifested by nasal congestion, lacrimation, sneezing, dry mucous membranes, flushing, lack of taste and smell.

Pharmazoline is usually prescribed at the initial stage of the development of the disease. The drug helps to reduce the severity of the symptom complex. For adult patients, 3-4 drops of the solution are instilled into each nasal passage. The procedure is repeated up to 5 times a day. The interval between the use of the drug should be 4-5 hours. Children are instilled 1-2 drops of a nasal agent up to 3 times a day.

ARI

Pharmazolin is prescribed to patients with suspected acute respiratory infections. Acute respiratory diseases are characterized by damage to the respiratory tract, provoked by penetration into the body pathogenic microorganisms (mycoplasma, chlamydia, pneumococcus, streptococcus, staphylococcus, rheo-, adeno-, herpes-, entero- and rhinoviruses).

With acute respiratory infections, patients complain of fever, inflammation of the laryngeal mucosa, swelling of the nasopharynx, cough, congestion, mucous or purulent nasal discharge. Pharmazoline is prescribed for adult patients according to the standard scheme - no more than 3 drops once in each nostril. You can instill the drug 3-4 times a day. The scheme for using the solution for children is no more than 2 drops 3 times a day.

Side effects

The drug is usually well tolerated by patients. Subject to the regimen of use and dosage regimen, side effects do not occur often. Ailments may appear against the background of self-exceeding the therapeutic dose.

The instructions for use indicate the following side effects:

• on the part of the musculoskeletal system: involuntary muscle contractions (usually sudden);
• on the part of the respiratory system: a short-term increase in swelling, rupture of capillaries, provoking bleeding, dryness of the mucous membrane, sneezing attacks;
• from the organs of the digestive tract: attacks of nausea, bitterness in the mouth;
• on the part of the cardiovascular system: increased heart rate, surges in blood pressure, tachycardia (more than 90 beats per minute);
• from the central nervous system: falsely perceived images and objects, sleep disturbances (insomnia or drowsiness), severe headache of a pulsating nature.

People with weakened immunity may develop allergic reactions, which manifest themselves in the form of itching, rashes, and redness. The risk of developing angioedema in hypersensitive patients is relatively high. In some cases, there is a burning sensation of the mucous membrane immediately after instillation.

Overdose

The characteristic symptoms of an overdose occur when the daily norm is independently exceeded by 5-7 times (more than 0.3 mg / kg). The patient's state of health deteriorates gradually. At first, he begins to complain of increased heart rate, increased fatigue and spikes in blood pressure. In the absence of adequate treatment, violations of the functional activity of the nervous and circulatory systems are observed.

Emotional overexcitement is accompanied by convulsions and hallucinations. The patient becomes lethargic and apathy may occur. With a critical excess of the therapeutic norm (more than 1 mg / kg), the likelihood of developing a coma increases.

Overdose is also characterized by the following symptoms:

• apnea;
• lowering blood pressure;
• disorders of the systemic circulation;
• swelling of the lungs;
• increased heart rate;
• ventricular asystole;
• bradycardia;
• bouts of nausea;
• tachycardia;
• blanching of the skin;
• excessive sweating;
• partial loss of vision.

If characteristic symptoms of an overdose appear, it is necessary to immediately call an ambulance team or independently deliver the patient to the nearest medical facility. After a detailed examination, the patient is prescribed therapy. When diagnosing seizures, anticonvulsant medications are required. Indiscriminate adrenergic blockers help to normalize blood pressure. It is strictly forbidden to take vasoconstrictor drugs.

special instructions

Pharmazoline restores breathing. Drops in the nose, the price of which varies between 45-70 rubles. also eliminate congestion.

Despite the relative safety, careful use of Pharmazoline is necessary for patients suffering from:

• pheochromocytoma;
• non-toxic single-nodular goiter;
• benign prostatic hyperplasia;
• diabetes mellitus;
• porphyria;
• coronary insufficiency.

People suffering from hypersensitivity to sympathomimetics may need to adjust the dosage regimen (usually towards a decrease in the daily rate). This category of patients has a high risk of developing dizziness and various sleep disorders. The drug can be addictive, so it cannot be used on a regular basis. One bottle cannot be used by several people.

Drug interactions

It is strictly forbidden to simultaneously use Pharmazolin and medicines that can inhibit the autonomic nervous system. Beta blockers in combination with xylometazoline can cause spasms in the lungs and bronchi. It is strictly forbidden to use Pharmazolin simultaneously with antidepressants and MAO inhibitors. Expectorant and mucolytic drugs can be included in the drug therapy along with nasal drops.

Analogs

Vasoconstrictor drops have a number of structural analogs and generics with similar therapeutic effects.

These include:

Name	Components, dosage forms	Indications	Contraindications	Instructions
Grippostad Reno	The drug is marketed in the form of drops and spray. The active ingredient is xylometazoline (in the form of hydrochloride). Excipients - glycerin, citric acid (monohydrate), water.	The medication is prescribed for ear inflammation, hay fever, allergic rhinitis. Can be used at the first signs of acute respiratory infections, acute respiratory viral infections	The use of the drug is impossible during pregnancy, lactation, with atherosclerosis, atrophic rhinitis, hyperthyroidism, glaucoma.	The therapeutic norm of the drug for adults is not 2 drops once. The procedure is repeated 2-4 times a day.
Galazolin	Dosage form - drops, gel. The main substance is xylometazoline hydrochloride. Auxiliary components - water, sodium monohydrate, disodium edetate, sorbitol, sodium hydrogen phosphate, glycerol.	The medicine is prescribed for sinusitis, rhinopharyngitis, eustachitis, otitis media, allergic, bacterial, viral rhinitis.	Contraindications prescribed in the instructions: angina pectoris, diabetes mellitus, prostate adenoma, childhood, hypertension, thyroid hyperfunction, vascular occlusion.	For adult patients, 2-3 drops are instilled into each nostril. There is also a children's form of medication on sale.
Fornose	The medicine is marketed in the form of a spray and drops. The active ingredient is xylometazoline hydrochloride. Additional substances - sodium salt of hydrochloric acid, dihydrate, hydrogen phosphate, purified water, disodium edetate.	The drug can be used for sinusitis, rhinitis of various etiologies, inflammation of the ear canal, eustachitis. The medicine is also prescribed before rhinoscopy.	Contraindications include the period of pregnancy and lactation, diabetes mellitus, prostate adenoma, hypersensitivity, glaucoma, hyperthyroidism.	For adolescents and adult patients, 2-3 drops are instilled into each passage. Children under 12 years old - 1-2 drops. The procedure can be carried out 2-4 times a day.
Xilen	Dosage form - spray and drops. The active substance is xylometazoline hydrochloride. Auxiliary components - water, disodium edetate, alkylbenzyldimethylammonium chloride, sodium hydrogen phosphate.	The main indications for use are inflammation of the paranasal sinuses or ear canal, ARVI, allergic rhinitis.	Contraindications are considered prostatic hyperplasia (benign tumor), diabetes mellitus, hyperthyroidism, atrophic rhinitis, eye neuropathy, atherosclerosis.	Adult patients are prescribed 2-3 drops in each passage. The procedure can be repeated up to 3 times a day. The remedy is not prescribed for children.
Xylometazoline	The drug is marketed in the form of a gel, spray, or drops. Auxiliary components - propylene glycol, glycerol, carbomer, sorbitol, benzalkonium chloride, potassium dihydrogen phosphate.	Indications for use - eustachitis, inflammation of the paranasal sinuses, rhinopharyngitis, bacterial, viral, allergic rhinitis.	The use of the drug is contraindicated in people suffering from diabetes mellitus, optic neuropathy, thyrotoxicosis, tachycardia, angina pectoris.	For adult patients, 2-3 drops of the drug are instilled into each nostril. Children under 6 years of age are not prescribed medication.
Xymelin	Dosage form - drops and spray. The main component is xylometazoline hydrochloride. Additional elements - purified water, disodium edetate, benzalkonium and sodium chloride.	The drug can be used for otitis media, sinusitis, pharyngitis, allergic rhinitis.	Contraindications for use are considered children's age (up to 2 years), pregnancy and breastfeeding, hyperthyroidism, thyrotoxicosis, glaucoma, tachycardia.	For adolescents and adult patients, 1-3 drops can be instilled into each nostril. The daily norm for children under 12 years old is no more than 6 drops.
Otrivin	Comes on sale in the form of a spray and drops. The active substance is xylometazoline hydrochloride. Additional elements - eucalyptol, levomenthol, purified water, sodium salt of hydrochloric acid, hexahydric alcohol alkylbenzyldimethylammonium chloride.	Nasal drops and spray can be used for rhinoconjunctivitis, acute rhinitis, eustachitis, inflammation of the ear and paranasal sinuses.	The use is prohibited for glaucoma, atherosclerosis, tachycardia, hyperthyroidism, hypertension, atrophic rhinitis.	Children under 12 years of age are not prescribed medication. The therapeutic norm for adult patients is no more than 3 drops once. The daily dose is 6-9 drops.
Tizin Xylo	The drug is marketed in the form of a nasal solution. The active ingredient is xylometazoline hydrochloride. Auxiliary components - sorbitol, purified water, sodium hydrogen phosphate, benzalkonium and sodium chloride, disodium edetate.	The medication can be used for allergic, traumatic, bacterial and viral rhinitis, sinusitis, otitis media, acute respiratory infections.	The use of the drug is contraindicated in people suffering from glaucoma, angina pectoris, tachycardia, atherosclerosis, atrophic rhinitis, hypertension. Individual intolerance can also be considered a contraindication.	The drug is not prescribed for children under 6 years of age. Adult patients instill 2-3 drops in each passage. The daily norm is no more than 9 drops for adults, for children - no more than 6 drops.
Snoop	The drug is marketed in the form of a nasal solution. The active ingredient is xylometazoline. Excipients - purified sea water, potassium hydrogen phosphate.	The use of the medication is possible with sinusitis, eustachitis, allergic rhinitis, hay fever, otitis media.	Contraindications are pregnancy, lactation, thyrotoxicosis, atrophic rhinitis, glaucoma, hypertension, atherosclerosis, tachycardia.	Children under 6 years of age are not prescribed medication. The therapeutic norm for adult patients and adolescents is no more than 2 drops once. The daily dose is 9 drops.

If the instructions for use are not followed, there is a high risk of side effects. If ailments appear, immediate discontinuation of the drug is required.

Terms of sale, storage and prices

Opened vials with nasal solution must be stored in a dry, dark place. After the expiration date, the use of Pharmazoline is strictly prohibited. The medication does not require a prescription from pharmacies. The cost of the drug varies between 100-150 rubles.

Pharmazoline - nasal drops that can quickly eliminate congestion. The price of a medicine may vary depending on the method of sale (in online stores it may cost more). The shelf life of the medicinal product is no more than 5 years.

Video about the drug Pharmazolin

Pharmazoline drops description and instructions: