Rinofluimucil spray in the nose. Instructions for use, price, reviews

Rinofluimucil is a modern remedy, which is intended to eliminate diseases of the paranasal sinuses, nasopharynx and nose. The spray is recommended for use when vasoconstrictor medications do not help get rid of the problem, strictly following the instructions.

Composition and form of release

Rinofluimucil is a nasal spray presented in the form of an almost transparent, colorless solution that has a pleasant mint smell.

The following substances are considered the active components of the drug:

• 0.5 g of tuaminoheptane sulfate;
• 1 g acetylcysteine.

Also, the spray contains auxiliary elements:

Substances	Volume in grams
96% ethyl alcohol solution	0,31
Mint based flavor	0,0188
Benzalkonium chloride	0,01
Disodium Phosphate Dodecahydrate	0,3
Disodium edetat	0,02
Dithiothreitol	0,1
Methyl hydroxypropyl methylcellulose	0,75
Sodium hydroxide	0,36
Sodium dihydrogen phosphate monohydrate	0,3
Purified water	about 100 ml
Sorbitol 70%	2

Terms of sale, prices

The metered spray is available in darkened glass containers with a volume of 10 ml. Includes a spray bottle. The cardboard box contains 1 set.

The drug is dispensed without a prescription. The cost of the drug is approximately 259 rubles. It can be purchased at any pharmacy.

Pharmacological properties

Rinofluimucil is a drug used to treat diseases of the nasal cavity. The product has a decongestant and mucolytic effect.

Thanks to the active component acetylcysteine, mucopurulent and mucous secretions are very quickly liquefied, which provokes the rupture of disulfide bonds of mucus glycoproteins.

The active substance exhibits an anti-inflammatory effect by means of a mechanism for stopping the increase in the volume of leukocytes. In this case, the component has an antioxidant effect.

Acetylcysteine ​​has a slight toxic effect and a high range of therapeutic effects, depending on the dosage of the agent and the routes of its administration.

When the spray is applied topically, the active ingredient in the form of tuaminoheptane sulfate contributes to vasoconstrictor effect without systemic effects, eliminating puffiness and hyperemia of the membranes mucous membrane.

When eliminating inflammation processes developing in the paranasal sinuses and nasal cavity, reparative and mucolytic the effects of acetylcysteine ​​are complemented by the vasoconstrictor effect of tuaminoheptane sulfate, which prevents the development of swelling. Due to this, when using the drug, the mucous membranes of the nasal passages heal very quickly, and the symptoms of inflammation processes are reduced.

If the agent is used locally, its active ingredients will not exhibit a systemic character.

Active molecules will be established in the urine for 46 hours after the last irrigation. Systemic exposure to tuaminoheptane sulfate will be minor. Despite the fact that it does not provoke an increase in body temperature, it increases the absorption of oxygen by the tissues from the blood.

Pharmacodynamics and pharmacokinetics

On the part of pharmacodynamics, the reparative and mucolytic effects of acetylcysteine ​​in the treatment of inflammatory processes paranasal sinuses and nasal cavity, supplemented by the vasoconstrictor effect of tuaminheptane sulfate, which helps to get rid of swelling.

Due to the above effects of the agent, the mucous membranes of the nasal passages are very quickly restored, while the symptoms of the inflammation process are reduced.

From the side of pharmacokinetics, the composition will not be absorbed if it is used locally, in compliance with the indicated dosages.

Indications for use

Rinofluimucil is a spray in the nose, which is indicated in the presence of the following pathologies:

• vasomotor rhinitis;
• subacute with acute coryza;
• rhinitis of a chronic nature;
• sinusitis.

If the composition is used to treat other inflammatory processes, it will not have the desired effect.

Contraindications

Rinofluimucil with caution and only under the supervision of a treating specialist should be prescribed to children under 3 years of age.

Also, a spray in the nose should be used with caution in the presence of the following pathologies:

• bronchial asthma;
• arterial hypertension;
• regular extrasystole;
• angina pectoris 3 and 4 classes.

Contraindications to the use of a medicine:

• high sensitivity to one of the composition elements;
• angle-closure glaucoma;
• during the course of the treatment course, as well as for 14 days after the completion of the course with the use of monoamine oxidase inhibitors and tricyclic antidepressants;
• thyrotoxicosis.

Method of administration and dosage

Due to the nebulizer, the spray agent is required to be injected into the cavity of the nasal passages.

Optimal dosage:

• for adults - make 2 irrigations in the nasal passages, 3-4 times within 24 hours;
• for children - it is enough to introduce 1 irrigation into each nasal passage, 3-4 times for 24 hours.

The duration of medical therapy should be no more than 7 days. It is undesirable to increase the recommended dosage and exceed the therapeutic course without the agreement of the treating doctor.

The method of use and dosage regimen for a particular drug will depend on the type of release and other factors. The optimal dosage is determined only by a specialist. Therefore, it is required to strictly adhere to the dosage regimen and indications for use in accordance with the applied dosage form of a particular agent.

Step-by-step description for using Rinofluimucil:

1. Remove the cap from the container with the contents.
2. Dispose of the spray cap.
3. Fix the special attachment to the container.
4. Remove the lid from the spray nozzle.
5. Press to activate the spray.

To improve the therapeutic effect and prevent the manifestation of the "flooding" effect, preferably on during the course of the treatment, consume a large volume of alkaline liquid, as well as constantly cleanse the nasal passages. Adults are able to perform this procedure on their own. Children require an assisted nasal lavage with 0.9% sodium chloride solution, as well as mucus removal with suction.

The doctor for spray treatment can include antiseptic and antibacterial compounds with systemic or local effects. This will be relevant in the initial treatment stages, when the nasal discharge is thick and contains an admixture of pus.

Acetylcysteine ​​cannot be combined with beta-lactam antibiotics and tetracyclines. In this regard, between their use, it is required to maintain a time interval of about 2 hours. With the effectiveness of the treatment course, the mucus will be liquid and transparent, while it will gradually decrease.

Rinofluimucil is required to be administered intranasally. When the contents are added from a container to a container for the manufacture of compositions for inhalation, it will not have a visible result. The spray is not able to eliminate pathologies of the upper respiratory tract that follow the sinuses. Also, the composition is not able to remove phlegm from the bronchi and larynx, so it will not give the expected result in the treatment of tracheitis, laryngitis and bronchitis.

Acute rhinitis

Rinofluimucil is indicated for acute rhinitis. The disease is an inflammation of the lining of the nasal mucosa, which has been caused by various factors. A common form is rhinitis of an infectious nature, often referred to as a runny nose.

The disease can deliver certain risks to patients:

• if the process of inflammation has passed into the sinuses from the nasal cavity, the mucous membrane begins to swell, and the openings that connect the nasal cavity with the sinuses close, which leads to an aggravation of the condition;
• if a cold runny nose is long, there is a failure in the natural cleansing of the sinuses;
• if the course is unfavorable, the disease will acquire a chronic form, which has a severe and prolonged course;
• the discharge of mucus is suspended, it accumulates in the sinuses, and, upon contact with an infection, acquires a purulent form.

Acute sinusitis

It is an inflammation of the mucous membrane of the paranasal sinuses. The disease appears with ARVI, an acute form of the common cold, facial trauma and other infectious pathologies. Sinusitis is caused by bacteria with viruses.

Symptoms of acute sinusitis:

• mucus from the nose is thick;
• high body temperature;
• a feeling of heaviness in the frontal and paranasal region;
• with a sharp turn of the head, pain appears.

Antimicrobial therapy with sinus drainage is required to treat the disease. If the disease is viral, antibiotics are not needed.

Complications caused by acute sinusitis are more dangerous than the disease itself.

Complications of an infectious nature are formed in the soft eye tissues. As a result, an abscess or phlegmon appears. Dangerous bacteria with blood flow move through the tissue into the box of the skull, which provokes the formation of a purulent focus. The clinical picture looks like a cerebral abscess, as well as purulent pathologies of inflammation of the membranes of the brain.

Treatment should not be postponed so as not to aggravate the health condition. Rinofluimucil works well with acute sinusitis, if the problem is not started.

Antibacterial therapy

The drug is not suitable for antibacterial treatment, since the active ingredients do not contribute to the destruction of bacteria and cannot stop their spread, because they do not act as an antibiotic.

In the presence of bacterial rhinitis, the composition helps to liquefy and remove purulent clots that appear due to the vital activity of dangerous bacteria.

Sinusitis

For the treatment of pathologies that are caused by blockage and inflammation of the maxillary sinuses, only Rinofluimucil should not be used. It can act as an adjunct to the main therapeutic treatment. With the local influence of the remedy, the symptoms are alleviated.

To avoid complications, acute conditions require complex and timely treatment. It is necessary to prevent the congestion of mucus in the passages and sinuses of the nose so that an infection does not develop.

Side effects

Rinofluimucil is a spray in the nose, which, when taken for a long time, can contribute to the appearance of side effects in the form of changes in the normal activity of the nasal mucosa and sinuses. In this case, addiction to this drug composition may appear.

Side effects of the drug:

• arterial hypertension with tachycardia and strong heartbeat from the cardiovascular system;
• trembling, sometimes accompanied by excitement, from the nervous system;
• in the form of local reactions, dryness of the mucous membranes of the pharynx, oral and nasal cavities is manifested;
• sometimes there is inflammation of the sebaceous glands, urinary retention and an allergic reaction.

Overdose

When using the composition, according to the instructions, an overdose is unlikely.

If the required dose is exceeded, systemic side reactions caused by tuaminoheptane can increase:

• addictive;
• tachycardia;
• anxious states;
• tremor;
• increased blood pressure.

Therapeutic therapy should be symptomatic.

special instructions

The medicinal composition is recommended to be used with caution in the presence of the following pathologies:

• occlusive vascular diseases;
• bronchial asthma;
• hyperthyroidism;
• consumption of beta blockers;
• diabetes;
• an increase in the volume of the prostate gland (for this reason, urination may be difficult).

With prolonged use of the spray, nasal congestion with rhinitis medication may occur at the end of the drug intake. At the same time, addiction to the composition develops. When spraying, the spray should not come into contact with the mucous membrane of the eyes. Otherwise, you will need to rinse your eyes thoroughly.

The drug in the form of a preservative includes benzalkonium chloride, which is characterized by an irritating effect and the ability to provoke bronchospasm or skin reactions.

When using tuaminoheptane sulfate, a doping test can show a positive result. It is not recommended to use the spray during pregnancy. When undergoing a treatment course, it is required to suspend breastfeeding. The drug does not affect the reaction rate when driving vehicles or working with mechanisms. The spray is suitable for children over 2 years of age.

Drug interactions

Rinofluimucil is a nasal spray that is undesirable to use in conjunction with tricyclic antidepressants and MAO inhibitors. This is because there is an increased risk of systemic side effects associated with tuaminoheptane. Such drugs enhance the effect of sympathomimetic formulations. If the spray is used together with antihypertensive formulations, the effect of the latter is weakened.

Analogs

Analogs of Rinofluimucil are the following medicinal compositions with similar pharmacological properties:

• Alergomax;
• Vibrocil;
• Xymelin Extra;
• Evkazolin.

Vibrocil is considered a popular analogue, since it contains active components in the form of phenylephrine and dimethindene, which give an effect similar to Rinofluimucil.

Vibrocil is a combined remedy that effectively copes with various disruptions in the activity of the upper respiratory tract. It is characterized by a wider list of purposes and is produced in several forms, in particular in the form of a gel and drops. It is allowed to be used as a remedy for the treatment of sinusitis and rhinitis.

However, Vibrocil, unlike Rinofluimucil, is very expensive.

Storage conditions

The medicinal composition must be kept out of the reach of children, at a temperature not exceeding +25 ℃. The spray has a shelf life of 30 months. After opening the container, the contents will be suitable for treatment for 20 days. When the expiration date printed on the package has expired, the product must not be used.

Rinofluimucil is presented in the form of a nasal spray, which is suitable for the symptomatic treatment of pathologies associated with the nose and nasopharynx. The tool belongs to the pharmacotherapeutic group of decongestants. It is necessary to apply the composition according to the instructions indicated on the package, and only after agreement with the doctor, since there are contraindications. Otherwise, the condition can be aggravated.

Video about the drug Rinofluimucil spray

Rinofluimucil spray: