Aktiferrin (Aktiferrin) syrup for children. Reviews, price

Aktiferrin syrup is a Germanic drug that is used to normalize the level of iron in the blood. Aktiferrin is distinguished by its high efficiency, as well as a significant list of contraindications and dangerous symptoms in case of an overdose. Therefore, before using a medication to treat children, it is important to exclude all prohibitions and strictly observe the dosage.

Composition and form of release

Aktiferrin syrup is a medium-thick transparent solution with a yellow-green or orange-brown tint. The product has a pleasant raspberry-creamy aroma and is placed in an amount of 100 ml in bottles made of brown glass. The bottle is equipped with a special dispensing dropper stopper and a plastic cap, with protection against accidental opening. The medication is placed together with the instructions in a cardboard box.

The syrup contains:

List of components	Component Description
The main component
Ferrous sulfate	The substance allows you to quickly replenish the iron deficiency in the blood and eliminate the development of anemia.
D, L-cepin micronized	The element normalizes the activity of neurons and the functioning of brain cells
Minor components
Ascorbic acid	The component has antioxidant properties, takes part in redox processes, improves metabolism, and also replenishes vitamin C deficiency.
Ethanol	The substance acts as a preservative and also has a disinfectant and local irritant effect.
Raspberry flavor	The element gives the syrup a raspberry flavor.
Creamy flavor	The component gives the syrup a light creamy aftertaste.
Invert syrup	The component gives the drug the desired thickness, as well as a pleasant sweet taste.
Purified water	The substance is necessary to give the syrup the desired texture and concentration.

For 100 ml of syrup there are 3.4 g of iron and 2.5 g of serine.

Terms of sale, prices

Aktiferrin (syrup for children can be bought at a pharmacy only after presenting a prescription from a pediatrician) must be stored at a temperature of 6 to 25 degrees and protected from sunlight. Subject to these recommendations, the shelf life of the medication is 2 years from the date of release.

The syrup should be kept away from children's accessibility. Since when taking a large amount of medication, the development of symptoms that threaten the child's life is possible.

Pharmacological properties

Syrup Aktiferrin belongs to a group of drugs used to eliminate anemia.

Pharmacodynamics and pharmacokinetics

Aktiferrin syrup for children after oral administration has the following effect on the body:

• increases the iron content in the blood, which plays an important role in metabolic and energy processes, and also participates in the transfer of oxygen to cells and tissues;
• improves the absorption of iron from food;
• has a mild antioxidant effect;
• restores redox reactions;
• improves metabolism;
• replenishes the deficiency of vitamin C in the body;
• has a light disinfecting effect;
• normalizes the activity of brain cells improving memory and attention.

An increase in iron levels is noted approximately 2-4 hours after taking the syrup. Stabilization of the level of iron in the body is noted after completing a course lasting from 2 to 3 months. The main substance crosses the placenta to the fetus, and also passes into breast milk. The medication is excreted with feces, sweat and urine.

Important. The daily requirement of the body for iron for adults is approximately 1-2 mg, and for children approximately 0.5-1.5 mg. It should be borne in mind that after taking Aktiferrin syrup, only 10% of the iron in the composition is absorbed. At the same time, part of it is concentrated in the form of reserves in the following organs: liver, bone marrow, spleen.

Indications for use

Syrup Aktiferrin is prescribed when diagnosing iron deficiency in the body, which can be caused by the reasons described below and be accompanied by the following symptoms:

List of indications
Causes	Profuse bleeding, both external (deep open wounds, frequent nosebleeds) and internal (open ulcer, blunt abdominal trauma); period of active growth; dysfunction of the bone marrow; malnutrition, including inadequate intake of iron in breast milk due to maternal anemia; poor absorption of iron from food, including due to a lack of B vitamins; chronic gastritis; the development of a tumor in the body; transferred infectious disease in severe form; difficult course of pregnancy, as a result, the child may have congenital anemia; premature birth of a child; multiple pregnancy; the presence of parasites in the body, for example, worms; food allergy; menstruation in adolescent girls; violation of hemoglobin synthesis; disruption of the intestines; taking medications that provoke the development of anemia, for example, hormonal medications, frequent use of non-hormonal anti-inflammatory drugs; after surgery.
Signs	Pallor and dryness of the skin; deformation and fragility of nails; dull hair; the appearance of cracks in the corners of the mouth, as well as on the palms and heels; frequent colds; lethargy and tearfulness; fast fatiguability; poor weight gain; loss of appetite; lagging behind in growth and development; low pressure; frequent fainting; an increase in the number of heartbeats; noise in ears; the presence of hemorrhoids; regular regurgitation in infants; violation of the stool; flatulence; the child chews on chalk or eats sand; an increase in the size of the spleen or liver; frequent dizziness.

The listed signs and reasons are not a direct prescription for taking Aktiferrin syrup, but if they are present, it is necessary to donate blood to the child to determine the amount of iron in the blood. Also, a medication can be prescribed by a doctor in order to prevent the development of anemia.

Contraindications

Syrup Aktiferrin is allowed to be used to treat children after excluding the following contraindications:

• intolerance to the components of the syrup or allergy to the composition;
• increased amount of iron in the blood;
• violation of iron metabolism and its accumulation in tissues;
• anemia not caused by iron deficiency in the body;
• anemia caused by lead poisoning;
• anemia that develops due to the rapid destruction of red blood cells;
• anemia due to a violation of the formation of red blood cells;
• violation of pigment metabolism;
• child's age up to 2 years.

In addition, there are conditional contraindications, that is, when the drug is allowed to be used, but under the regular supervision of a doctor and at an individual dosage:

• peptic ulcer of the duodenum and stomach;
• the development of inflammatory processes in the intestines;
• bronchial asthma;
• allergic diseases;
• severe liver dysfunction;
• renal failure;
• inflammation of the connective tissue and joints;
• blood transfusion;
• diabetes.

During pregnancy and lactation, Aktiferrin syrup is used only after being prescribed by a doctor.

Method of administration and dosage

Syrup Aktiferrin should be taken with food or before meals. In this case, the drug must be washed down with fruit tea or water. Do not use black tea, milk or coffee, these drinks impair the absorption of iron. Also, the effectiveness of the drug can be reduced: solid food, eggs, bread.

The classic dosage of Aktiferrin syrup, if the pediatrician has not prescribed another course of treatment:

• children from 7 to 12 years old should take 5 ml of the product 2-3 times every 24 hours;
• children from 2 to 7 years old are prescribed 5 ml 1-2 times a day.

In this case, the daily dosage must be calculated by the weight of the child, which is 5 ml of syrup per 12 kg of weight. The course of therapy depends on the dynamics of the normalization of iron in the blood. After stabilizing the hemoglobin level, experts recommend continuing the maintenance course for another 2-3 months in order to consolidate the result.

The dosage of Aktiferrin syrup, depending on the cause of the iron deficiency and age:

Anemia caused by	Age	Single and daily dose	Notes (edit)
Heavy bleeding	2-7 years	5 ml syrup in the evening.	Aktiferrin should be taken for about 1-2 months after the bleeding has been eliminated.
7-12 years old	5 ml of the product in the morning and evening.
Over 12 years old	5 ml of the drug in the morning, afternoon and evening.
A period of active growth	2-7 years	5 ml of medication in the morning.	The duration of use of the syrup is set individually.
Over 12 years old	5 ml of syrup 2 times within 24 hours.
Dysfunction of the bone marrow	2-7 years	5 ml of the product 2 times a day.	The syrup is used in combination therapy, which is determined strictly by the doctor.
7-12 years old	5 ml of the drug 3 times during the day.
Over 12 years old	5 ml of medication 3 times throughout the day.
Malnutrition	2-7 years	5 ml of Aktiferrin for lunch.	It is necessary not only to take syrup, but also to normalize nutrition.
7-12 years old	5 ml syrup at lunchtime and in the evening.
Over 12 years old	5 ml of the product 2-3 times a day.
Impaired absorption of iron	2-7 years	5 ml in the morning and at lunchtime.	Combination therapy is prescribed.
7-12 years old	5 ml in the morning, lunchtime and evening.
Over 12 years old	5 ml 3 times a day.
The presence of a tumor	2-7 years	5 ml at lunchtime and in the evening.	The therapy is carried out complex, which is established by the doctor.
7-12 years old	5 ml in the morning, lunchtime and evening.
Over 12 years old	5 ml up to 4 times throughout the day.
Postponed infectious disease in severe form	2-7 years	5 ml in the evening.	The syrup is taken within 2-3 months (depending on the dynamics of treatment).
7-12 years old	5 ml in the morning and at bedtime.
Over 12 years old	5 ml 3 times for 24 hours.
Congenital anemia	2-7 years	5 ml in the morning and at lunchtime.	The course is long and can be up to six months.
Gastritis and bowel disruption	2-7 years	5 ml in the afternoon.	The duration of therapy is selected individually.
7-12 years old	5 ml day and evening.
Over 12 years old	5 ml 3 times during the day.
Food allergy	2-7 years	5 ml 1-2 times every 24 hours.	Long-term treatment, while at the same time it is necessary to take antihistamines.
7-12 years old	5 ml 2-3 times throughout the day.
Over 12 years old	5 ml 2-4 times a day.
Abundant menstruation in girls	over 12 years old	5 ml 2-3 times for 24 hours.	The syrup should be taken 10 days from the first day of menstruation.
Violation of iron synthesis	2-7 years	5 ml morning and evening.	The syrup is used in complex therapy prescribed by a doctor.
7-12 years old	5 ml in the morning, lunchtime and evening.
Over 12 years old	5 ml up to 4 times every 24 hours.
Consequence of taking medications	2-7 years	5 ml 1-2 times a day.	The duration of the course is on average 3-4 months.
7-12 years old	5 ml 1-3 times a day
Over 12 years old	5 ml 2-3 times every 24 hours.
After operation	2-7 years	5 ml in the afternoon.	The duration of the use of the syrup is selected individually.
7-12 years old	5 ml in the morning and at lunchtime.
Over 12 years old	5 ml 2-3 times a day.
Prevention of the development of anemia	2-7 years	5 ml in the morning.	Additionally, you should enrich the diet with iron-containing foods.
7-12 years old	5 ml in the morning and at lunchtime.
Over 12 years old	5 ml 2-3 times every 24 hours.

The data in the table are approximate, since depending on the severity of the cause that caused the anemia and the weight of the child, the dosage value may vary.

The syrup bottle is equipped with a special lid with protection against accidental opening. Therefore, to open the bottle, you must first push on the cap and simultaneously turn it in the direction of the arrow (indicated on the cap). After use, close the bottle back with the lid until it stops.

Side effects

Aktiferrin (syrup for children) rarely causes the development of a negative reaction, but it is possible that during the course (especially long-term) the appearance of the following side effects:

• stomach ache;
• decreased or loss of appetite;
• a feeling of a bitter taste or metal in the mouth;
• bloating with gas;
• bowel disruption in the form of constipation or frequent bowel movements;
• headache;
• rush of blood in the skin, often to the face;
• dizziness;
• allergy symptoms. More often, the appearance of a rash, skin itching is noted. The development of suffocation is not excluded;
• toothache;
• nausea, vomiting is not excluded immediately after taking the syrup;
• a sore throat;
• feces become dark in color;
• fatigue, weakness;
• a feeling of squeezing in the chest;
• increased irritability.

The listed side effects (except for allergies) are not the reason for discontinuation of the drug. To eliminate them, it is enough to reduce the dosage of the syrup.

Overdose

If the dosage is not observed and when the syrup is taken in a large dose, the development of poisoning is noted, which in children is manifested by the following symptoms:

• severe weakness and fatigue;
• burning and tingling sensation on the skin;
• pronounced pallor of the skin;
• sticky and cold sweat appears;
• a rapid drop in blood pressure;
• palpitations;
• cyanosis of the skin, especially on the limbs;
• severe abdominal pain;
• frequent and loose stools, possibly blood in the stool;
• profuse vomiting;
• blue discoloration of the nasolabial triangle;
• violation of consciousness;
• the pulse is poorly felt;
• rush of blood to the skin;
• slowing down reactions;
• the appearance of seizures;
• violation of blood coagulation;
• signs of hyperventilation.

The development of a coma is not excluded.

When using syrup in a very large dose (more than 1 g of iron at once) within 30 minutes, the victim has:

• severe acid-base balance disorder;
• severe cramps;
• a sharp rise in temperature;
• an increase in leukocytes in the blood;
• violation of consciousness;
• intense thirst;
• coma;
• violation of the rhythm of heart contractions;
• severe joint pain;
• the skin takes on a bronze tint;
• necrosis of the kidneys and liver.

The listed symptoms appear within 12-96 hours.

To normalize the victim's condition, the stomach should be flushed if no more than 30 minutes have passed from taking the medication. Additionally, the patient should drink milk or raw eggs. They will impair the absorption of the drug.

Deferoxamine is used to bind and remove excess amount of the drug from the body.

At the same time, depending on the degree of poisoning, the method of using the drug changes:

• with the development of acute poisoning, if the iron has not yet been absorbed, the victim should take orally 5-10 g of Deferoxamine dissolved in water;
• if the drug has already entered the bloodstream (in case of moderate poisoning), then the agent is administered intramuscularly in an amount of 15 mg per hour;
• in case of mild poisoning, 1 g of Deferoxamine is administered every 4-6 hours;
• in case of severe poisoning, Deferoxamine is administered drip in an amount of 1 g.

Important. Hardware purification of blood is not effective for removing Aktiferrin from the body.

special instructions

Aktiferrin syrup for children, in order to reduce the likelihood of developing side effects, should be taken in compliance with the following special instructions:

• when undergoing a course of therapy, a blood test should be taken every 14 days, in order to improve the dynamics of treatment and normalize iron levels;
• so that the tooth enamel does not darken, after taking the syrup, brushing the teeth is required, and the medication should not be taken undiluted;
• it is undesirable to combine the intake of syrup with dietary supplements containing iron salts, since the development of an overdose is possible;
• Aktiferrin causes irritation of the mucous membranes of the gastrointestinal tract. Therefore, in the presence of pathologies in the digestive tract, use the syrup with extreme caution;
• with diabetes mellitus, use the drug with caution, since it contains a sufficient amount of glucose;
• be sure to exclude all contraindications before using the drug.

It is strictly forbidden to calculate the dosage yourself, it should be prescribed by a doctor. Since it is required to take into account not only the weight of the child, but also his general condition and the presence of chronic diseases.

Drug interactions

Before starting the course, the attending specialist must warn with which food products the syrup intake cannot be combined. If a combination treatment is prescribed, then the doctor should clarify the compatibility of the medications.

Syrup Aktiferrin should not be combined with:

• Deferoxamine. The medication binds iron and removes it from the body. Therefore, the drug is used as an antidote for poisoning;
• drugs and foods that reduce acidity in the stomach, impair the absorption of the drug;
• ascorbic acid increases the absorption of Aktiferrin;
• non-hormonal anti-inflammatory drugs and syrup, when taken simultaneously, have a strong irritating effect on the organs of the digestive tract;
• vitamin E, zinc-containing preparations are absorbed worse when taken simultaneously with Aktiferrin;
• alcohol-containing medicines increase the toxic effect of the syrup.

The drug reduces the effectiveness of antibiotics of the tetracycline, penicillin and fluoroquinoline groups.

To prevent the drugs from interacting, at least 2 hours should pass between doses of medications.

Analogs

If Aktiferrin syrup is not suitable due to contraindications or is not available for sale, then it can be replaced with the following medicines:

• Sorbifer Durules. 350 rubles;

  

• Totem. RUB 400;
• Hemoferon. 650 rubles;
• Gyno-tardiferon. 750 rubles;
• Hemofer. 250 rubles;
• Heferol. 650 rubles;
• Tardiferon. RUB 200
• Ferumbo. 450 rubles;
• Maltofer. 250 rubles;
• Fer-Rompharm. - 700 rubles;
• Ferlatum. RUB 400;
• Ferrum lek. 150 rubles;
• Fersinol. 650 RUB

An analogue should be selected by a pediatrician, taking into account the age and the reason for replacing the medication.

Syrup Aktiferrin is able to normalize the level of iron in the blood in a fairly short time, but at the same time the drug is dangerous with the development of side effects, especially if the drug is taken for a long time or in a large dose. In this regard, when using the drug for the treatment of children, the dosage must be strictly observed.

Author: Kotlyachkova Svetlana

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