Oftalmoferon (Oftalmoferon) eye drops. Reviews, instructions for use, cheap analogues, price

Ophthalmoferon is drug in the form of eye drops, recommended for the treatment of viral and allergic diseases of the mucous membrane of the eyes. According to reviews, they are well tolerated and quickly lead to a significant improvement in well-being and suppression of pathological symptoms.

Indications for use

Oftalmoferon - eye drops, reviews of which in most cases contain information about the purposes of use, should be used with the following indications:

• inflammatory processes of a viral or bacterial nature;
• allergic and atopic conjunctivitis;
• ulcerative lesions of the cornea;
• postoperative period.

An additional non-specific indication is the use of the drug as an artificial tear for dry eyes.

Compound

The composition of the medicinal solution includes the following components:

• interferon - at a concentration of 10,000 IU in 1 ml, the substance suppresses the activity of viruses and stimulates local immunity;
• diphenhydramine - a powerful component against allergies and the development of inflammatory processes, relieves pain, 1 mg per 1 ml;
• boric acid - has an antibacterial effect against the background of the development of viruses, 3.1 mg per 1 ml.

The following components are included in the preparation as auxiliary substances:

• polyvinylpyrrolidone - 10 mg;
• polyethylene oxide - 50 mg;
• sodium chloride - 4 mg;
• hypromellose - 3 mg;
• sodium acetate - 7 mg;
• Trilon B - 0.4 mg.

Externally, the drug is a clear solution without color and foreign inclusions.

In what form is it produced

Oftalmoferon - eye drops, reviews of which contain information and the form of release, are presented in pharmacies in the form of drops in plastic bottles with a volume of 10 ml, equipped with a dropper with a screw-on cover. The drug, together with the instructions for use, is placed in a cardboard box for storage in a refrigerator.

Pharmacodynamics

Interferon, used to make Ophthalmoferon drops, belongs to genetic engineering products and is not associated with human blood leukocytes for its production.

Due to this, the starting material for the production of the drug is distinguished by a high degree of purification from unwanted impurities and is absolutely safe in terms of the risk of transmitting other viruses to the patient, including HIV, cytomegalovirus and hepatitis. In high concentrations, it quickly and effectively blocks the activity of less dangerous viruses.

Diphenhydramine belongs to the 1st generation H1-histamine receptor antagonists. The substance actively eliminates the effects of the effect on the histamine receptors of the eye. As a result, even in severe forms of allergic reactions, diphenhydramine has a quick and powerful regenerating effect.

Boric acid also has a multifaceted therapeutic effect on the mucous membranes of the eye:

• fungicidal - has a narrow pharmacological activity against fungi;
• bacteriostatic - stops the growth and reproduction of microorganisms;
• bactericidal - causes their subsequent death.

Boric acid easily penetrates into the mucous membranes and, with regular instillation of the solution, accumulates in them. As a result, the healing effect gradually increases.

Excipients in the composition of the preparation stabilize the active components, give the solution the required characteristics and facilitate the delivery of the components to the mucous membranes of the entire eye.

Pharmacokinetics

When applied topically, systemic absorption practically does not occur, the drug has an effect only at the local level. The content in the blood does not exceed the lower limit of detection capabilities. Therefore, no clinically significant reactions were identified during the studies.

Application

The drug is intended for conjunctival use by instillation the recommended number of drops in the conjunctival sac:

• before using the drug, you must thoroughly wash your hands with warm water and soap;
• touching the eyes, especially in the acute stage of the disease, is allowed only with dry hands;
• for accurate dosing, it is recommended to use a mirror to fully control the process;
• when using the drops on your own, you should slightly tilt your head back and slightly pull the lower eyelid with one hand;
• in this case, the gaze should be directed upward;
• for dosing, the bottle with the solution must be taken in your free hand and, holding it to the eye, without touching the mucous membrane of the eye, you need to squeeze out the required number of drops;
• immediately after that, it is recommended to rotate the eyeballs in all directions, and then gently massage both eyelids;
• when performing the described actions, excessive efforts should be avoided in order to avoid the release of solution from the conjunctival sac.

It is always recommended to instill the drug in both eyes, since most types of infections easily spread from the diseased focus to healthy tissues.

For children under 18

With symptoms of acute conjunctivitis of various etiologies, the drug should be used 1-2 drops every 3-4 hours during the day. It is recommended to continue treatment in this mode until the beginning of recovery. After the first improvement, it is allowed to reduce the frequency to 2-3 times a day. Treatment must be continued until the pathological symptoms disappear completely.

For adults

Adult use should be similar to childhood use. With especially acute symptoms, the dose can be increased to 3 drops at a time, procedures can be repeated up to 10 times a day. In the case of a general infection of the body with viral or bacterial types of infections, it is necessary to combine treatment with drops with systemic antiviral and antibacterial drugs.

For pregnant

Oftalmoferon - eye drops, which, according to patients' reviews, can be successfully used during pregnancy. Due to the lack of a systemic effect, possible harm to the fetus is practically excluded. In addition to the period of pregnancy, the drug is allowed to be used during breastfeeding of a newborn baby.

Elderly

Older people can use the remedy without restrictions even against the background of more serious diseases, such as cataracts, problems with the retina and other pathologies. The dosages in this case are similar to those recommended for adult patients.

Contraindications

The drug has no significant contraindications. Restrictions on its use can be associated only with individual intolerance to active substances or auxiliary components.

Overdose

No overdose cases have been reported.

Side effects

Side effects were also not noted.

Drug interactions

The drug is well compatible with other agents for relieving inflammatory reactions, suppressing the activity of viruses, hormonal substances and stimulants of tissue regeneration. No adverse interactions were noted.

Storage conditions and periods

Ophthalmoferon - eye drops, reviews of which about their therapeutic effect largely depend on activity active ingredients must be stored exclusively in the cold at an ambient temperature of 2 ° C to 8 ° C.

The general shelf life is 2 years from the date of production. After the first opening, the contents of the bottle should be used within 1 month. After the expiration of this period, the drug should be disposed of with household waste.

Conditions of dispensing from pharmacies

The drug does not require a prescription from an observing specialist, but uncontrolled use is also unacceptable. In some cases, self-medication can be harmful to health if the drug is selected without taking into account the indications and features of the symptoms.

Analogs

In addition to viral infections, the addition of bacterial flora is often observed against their background. The symptomatology in this case is greatly enhanced.

Signs of viral conjunctivitis:

• significant redness of the mucous membrane;
• mucous discharge from the eye;
• swelling of the eyelids.

This makes the eyes look sore and puffy. When instilling medicinal solutions, painful sensations and a burning sensation are often noted.

In the case of a bacterial infection, the following signs are added to the symptoms:

• the formation of significant amounts of yellowish pus;
• it can be difficult for patients to open their eyes in the morning;
• when washing, the crusts soften and are removed;
• further, the secretions are formed again.

In most cases, a combination of drops of Ophthalmoferon and sodium sulfacil, better known in wide circles as albucid, is sufficient for full treatment and quick recovery. In mild cases, it can also be used for monotherapy, since it also has antiviral activity.

There are currently no complete analogues on the Russian market. Therefore, to enhance its action or for a systemic approach to treatment, it is allowed to use other effective drugs in the form of rectal suppositories or capsules for internal administration.

Candles Genferon

The drug is available in the form of rectal suppositories in the following dosages:

• Genferon Light 125000 IU of interferon + 0.005 g of taurine;
• Genferon Light 250,000 IU of interferon + 0.005 g of taurine;
• Genferon 1,000,000 IU;
• Genferon 500,000 IU.

The listed drugs are produced in the form of torpedo-shaped suppositories for administration into the rectum. The dosage depends on age and on the severity of the current symptoms. When applied topically, the drug is well absorbed by the intestinal walls and has a systemic effect on the entire body, including the mucous membranes of the eye.

Other analogues do not contain taurine, but it has been proven that this substance helps to stabilize metabolic processes in tissues and accelerates regeneration. Additionally, taurine stabilizes the function of cell membranes and strengthens the immune system.

Since taurine is a powerful antioxidant, it actively neutralizes activity free radical molecules, the excess of which often becomes the cause of pathological processes in the human body.

Application and dosage:

• 125,000 IU - for children under 7 years old;
• 250,000 IU - for children from 7 years old;
• from 500,000 IU - at the age of 18 years.

The number of applications per day and the duration of therapy should be agreed with the attending physician.

After the start of the course of treatment, Genferon, like other interferon preparations, is able to provoke a primary reaction of the body, which will be expressed in an increase in body temperature. This does not require discontinuation of therapy. To correct the condition, it will be enough to take an antipyretic agent.

Reaferon-EC Lipint lyophilisate and capsules

Oftalmoferon - eye drops, reviews of which contain information about local application, can be supplemented with funds from the Reaferon-EU line. As an active substance, the preparations contain human recombinant interferon alpha-2b. Depending on the purpose and the recommended age of the patients, the product is available in the following forms and dosages.

Dosage	Number of vials in 1 package
250,000 IU	5 or 6 bottles per pack
500,000 IU	5 or 6 bottles per pack
1,000,000 IU	5 bottles in a pack
3,000,000 IU	5 bottles in a pack
5,000,000 IU	5 bottles in a pack
5,000,000 IU	10 capsules in a jar

The drug is intended specifically for internal use. The gelatinous membrane protects the active substance and ensures complete absorption by the intestinal walls.

The mechanism of the therapeutic action consists in the active introduction of viruses into the reproduction processes by disrupting metabolic processes inside the cells. Interferon stimulates the synthesis of specific cytokines and enzymes, the action of which prevents the formation of proteins in the composition of viruses and RNA in their cells.

The mode of application depends entirely on the goals and severity of the patient's current condition. A separate indication that recommends taking the drug urgently is the emergency prevention of tick-borne encephalitis.

Standard recommendations:

• for the treatment of influenza and ARVI - 1 capsule 2 times a day for 5 days;
• for the prevention of influenza and ARVI - 1 capsule 2 times a week, 1 month.

If it is difficult to swallow the capsules, it is allowed to open them and mix the contents with a small amount of cool water. Overdose cases have not been reported.

Eye drops Poludan

The drug has pronounced antiviral and immunostimulating properties.

It contains the following substances:

• polyriboadenylic acid - 100 units;
• polyriburidylic acid - 100 U

As auxiliary components, the preparation also includes sodium chloride - 8.5 mg, sodium hydrogen phosphate - 2 mg and potassium hydrogen phosphate - 0.408 g. The active substances start the synthesis of interferon inside the body, which immediately proceeds to neutralize viruses and suppress their vital activity.

Under their influence, after a few hours, the amount of interferons in the blood significantly increases and lacrimal fluid, due to which a therapeutic effect against viral conjunctivitis develops immediately etiology. Basically, interferon α is induced, to a lesser extent - type ß interferon.

Indications for use:

• optic neuritis;
• keratononjunctivitis;
• conjunctivitis;
• keratouveitis;
• keratitis.

The drug is a powder in the form of a dry lyophilisate for the preparation of a medicinal solution. To activate the powder, it must be diluted with 2 ml of distilled water. After complete dissolution of the mass, the composition will become ready for therapeutic use. The guaranteed shelf life after dilution is 1 week, subject to storage conditions, no more than + 4 ° С in a refrigerating chamber.

Before using the composition, be sure to wash your hands with warm water and antibacterial soap. Before dosing the solution, it is recommended to hold the bottle in your hands for a while so that the drug warms up a little.

In the presence of purulent and other discharge, the eyes must first be cleaned. Dosage - 1-2 drops into the conjunctival sac. After instillation, you should close your eyes for a while and let the active substances begin their therapeutic effect.

At the beginning of treatment, the regimen can reach 8 uses per day. As you feel better, the frequency can be reduced up to 4 times a day. The duration of treatment should be determined individually.

Ophthalmoferon is an effective remedy in the form of eye drops, which, without a systemic effect on the body, allows you to get rid of many unpleasant symptoms of certain diseases. According to reviews, compliance with the recommended dosages according to the standard regimen quickly removes all manifestations of acute pathology.

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