Ear drops are one of the methods of treating diseases related to the organs of hearing. Many of them contain antibacterial components designed to suppress various infections. These drugs include drops Tsipromed, the price of which allows you to use them when you need them.
Record content:
- 1 Composition, release form and price
- 2 Mechanism of action
- 3 Pharmacodynamics and pharmacokinetics
- 4 Can I drip into my eyes?
- 5 Indications for use
- 6 Contraindications and side effects
- 7 Overdose
- 8 Instructions and doses
- 9 special instructions
- 10 Drug interactions
- 11 Storage conditions and periods
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12 Analogs
- 12.1 Ciprofloxacin-SOLOpharm
- 12.2 Combined
- 12.3 Floximed
- 13 Video about drops Tsipromed
Composition, release form and price
The drug is manufactured by the Indian pharmaceutical company Sentiss Pharma Pvt. Ltd. ". The drug comes to retail in the form of medical plastic vials with liquid contents, equipped with a convenient dispensing device.
Volume - 10 ml with the concentration of the active substance ciprofloxacin - 0.3%.
The chemical formula is presented as lactate. The average cost of 1 package is about 150 rubles.
Mechanism of action
Tsipromed - ear drops, the price of which is determined by the relatively low cost of the active ingredient, acts due to its properties. Pharmacologically, ciprofloxacin belongs to the group of antimicrobial agents, fluoroquinolones.
In their activity, they are similar to antibacterial drugs, but they differ directly in the chemical structure and origin.
Antibiotics are a natural product, fluorolinolones are artificially synthesized substances that have no analogues in naturally occurring h The active substance inhibits 2 vital enzymes in the cells of microbes - DNA gyrase and topoisomerase-4. Under the influence of ciprofloxacin, DNA production is disrupted. The result is the death of microorganisms.
Additionally, the drug affects the stability of membrane septa and affects many other, most important processes of their life.
Due to the active ability to perform the described actions, the substance has become widespread in the production of medicines in the form of drops for the eyes and ears.
Pharmacodynamics and pharmacokinetics
Ciprofloxacin acts on both multiplying microbes and those in the resting phase. The substance exhibits bactericidal activity against a wide range of gram-negative microorganisms, including Klebsiella, Legionella, Streptococcus, Gardnerella, Moraxella and many other types.
Also, the drug acts against a number of gram-positive microbes and bacteria, including Staphylococcus aureus, some types of streptococci and Listeria. Ciprofloxacin belongs to the class of substances with low toxicity to humans.
Can I drip into my eyes?
Since eye drops and ear drops contain different forms of ciprofloxacin, it is not recommended to interchange them, despite the same concentration of the active ingredient. Also, the differences lie in the set of auxiliary substances that provide the level of acidity of the finished solution recommended for a specific zone.
Indications for use
Tsipromed - ear drops, the price of which is slightly higher than the cost of the drug intended for the eyes, but having a volume that is 2 times higher, recommended for the treatment of the following pathologies:
- external and internal otitis media in acute and chronic forms;
- preventive use before and after ear surgery;
- the period after injury with tissue damage;
- inflammatory processes in the Eustachian tube.
You can also use the tool as a prophylaxis after removing foreign objects from the deep parts of the external auditory canal.
In accordance with the manufacturer's recommendations, the drug should not be used in children under 15 years of age. The decision on the need and permissibility of using drops for young children can only be an observing specialist.
When prescribing the drug, a number of symptoms should be taken into account, in which the use of the drug will be advisable:
- throbbing pain in the temple area;
- shooting pains in the ear and ear canal;
- also, pain can be given to the area of the head or teeth;
- at night and while eating, the pain is usually worse;
- in the acute phase, there is an increased release of sulfur from the ears;
- darkening in the eyes and noise in the head are also observed;
- the tympanic membrane, if untreated, becomes severely inflamed;
- with palpation and pressure, significant pain is felt.
The danger of the disease lies in the fact that with the development of a severe form without timely initiation of treatment, the risk of perforation of the tympanic membrane significantly increases. At the same time, almost always in such cases, there is a release of purulent fluid, blood and mucous masses.
If the victim's own immunity can independently cope with pathological microorganisms, after 2-3 weeks the person's condition will gradually stabilize. The eardrum regains its integrity, and purulent and other discharge from the ear canal stops.
But the risk is also related to the fact that even with a positive outcome, there is almost always a significant decrease in hearing ability. In the future, this brings serious discomfort to the daily life of the affected person. Therefore, the treatment of otitis media, even in not too serious cases, should include the use of antimicrobial and antibacterial drugs.
Contraindications and side effects
Contraindications to the use of drops:
- hypersensitivity to the components of the drug;
- the period of pregnancy and breastfeeding;
- children less than 15 years old.
Side effects include allergic reactions, slight soreness and redness of the eardrum.
Overdose
With topical application, it is possible to increase or the appearance of side effects. If ingested accidentally, symptoms are usually absent.
Sometimes the following manifestations are observed:
- digestive disorders;
- dizziness;
- headache;
- anxiety.
To eliminate such signs of an overdose, special measures are not required, except for the usual help depending on the symptoms. At the same time, it is important to ensure an adequate supply of water and other fluids to the affected person's body.
Instructions and doses
Before using the drug, it is recommended to carry out hygienic procedures by washing and cleaning the ear canals with a soft tourniquet made of cotton wool or with a cotton swab dipped in warm water.
It is strictly forbidden to push foreign objects deeper than 1-2 cm.
Instructions for using drops:
- for the correct distribution of the active substance, it is recommended to instill the solution, lying on its side;
- before use, it is necessary to warm the bottle in hands to body temperature;
- adults should use the solution 3 times a day, 5 drops.
After that, it is recommended to pull the earlobe down and massage the tragus of the auricle. This will help distribute the solution to the inflamed tissues. After using the drug, it is advisable to remain in the same position for 2 minutes.
To completely eliminate the disease, it is imperative to continue the course of treatment for another 2 days after the disappearance of all symptoms.
special instructions
Tsipromed - ear drops, the price of which allows them to be used for a long time, can cause the development of superinfection, which is immune to further treatment. Therefore, it is not allowed to exceed the dosage and the recommended duration of therapy. With persistent and severe symptoms of otitis media and other pathologies, it is necessary to combine the course with antibacterial drugs of systemic action.
Drug interactions
The simultaneous use of drops in conjunction with other quinolones, including ciprofloxacin, can lead to the development of cell instability to sunlight. Moreover, the degree of its manifestation can be from moderate to severe.
Solutions containing ciprofloxacin should not be mixed with drugs with an acidity level of 3-4, especially if they are chemically or physically unstable.
Storage conditions and periods
The guaranteed shelf life of the drug before the first opening is 3 years from the production date indicated on the package. The shelf life after opening is no more than 1.5 months at an ambient temperature of no more than 25 ° C. The drug does not require refrigeration conditions and should not be frozen.
Analogs
Tsipromed - ear drops, the price of which allows you to freely use the drug, can be replaced with one of the similar medicines. They all work in much the same way. The cost in most cases depends on the country of origin and brand.
Ciprofloxacin-SOLOpharm
The drug is produced by the Russian pharmaceutical company Grotesk LLC. The remedy for the treatment of diseases of the ear canal is produced in plastic bottles with a volume of 5 ml, complete with a special dispenser for accurate use of the drug.
The volume of the medicinal solution in 1 package is 5 ml. The concentration of the active substance is 0.3%. The difference between the drug lies in the chemical formula. In this case, the manufacturer uses ciprofloxacin hydrochloride monohydrate.
In addition to being used for the ears, the drug is also intended for the treatment of eye diseases. The active ingredient in the preparation is supplemented with several auxiliary components.
| Substance in the composition of the drug | Content in 1 ml |
| Mannitol | 44 mg |
| Sodium acetate | 0.68 mg |
| Trilon B | 0.50 mg |
| Benzalkonium chloride | 0.1 mg |
| Purified water | up to 1 ml |
Additionally, acetic acid is added to the composition of the drug in quantities sufficient to obtain an acidity level in the range of 3.5-5.5.
The pharmacological activity of the medicinal solution is the suppression of DNA gyrase in bacteria. This leads to a violation of the reading of genetic codes during the growth of cells in the future. The result is the rapid death of microorganisms.
The drug acts on gram-negative bacteria during periods of cell division, on gram-positive bacteria - in the intervals between the same stages. Low toxicity to humans is due to the absence of DNA gyrase in the body. The drug is not effective against some serious infections, including ureaplasma, clostridia, treponema, and other more complex bacteria.
Recommendations for medical use:
- the medicinal solution must be dosed directly into the external auditory canal;
- before instilling the solution, local hygiene should be carried out by gently cleaning the ear with a cotton swab;
- the temperature of the drops should be close to body temperature, the bottle should be warmed up in the hands;
- the recommended number of drops is 3-4 pcs. up to 4 times a day or more, depending on the symptoms;
- after instillation, it is required to remain in the supine position for 5-10 minutes;
- the total duration of the course of treatment is from 5 to 10 days.
To enhance the effectiveness of the drug, it is allowed to use it by wetting the cotton flagellum with a solution in sufficient volume. After that, it is necessary to lay it deep enough in the ear canal and leave it until the next procedure. Turundas should be changed in accordance with the frequency recommended for instillation of the solution.
Combined
The drug is available in the form of drops for the eyes and ears. Manufacturer - Indian pharmaceutical company Sentiss Pharma Pvt. Ltd. ".
The composition of the drug includes a combination of 2 active ingredients, in 1 ml of solution:
- ciprofloxacin hydrochloride - 3 mg;
- dexamethasone - 1 mg.
Combined eye drops
High efficiency is provided by enhancing the antibacterial component with a glucocorticosteroid for topical use. In practice, dexamethasone, which is available in various dosage forms, has a rapid and powerful drug effects even in the most severe cases up to the development of generalized allergic reactions.
When applied topically, the substance is well absorbed and quickly removes allergic manifestations from the mucous membranes.
When used on the ears, it exhibits the following healing effects:
- prevents pathological cell proliferation;
- reduces the synthesis of collagen fibers;
- stimulates the activity of phagocytes;
- promotes the elimination of exudate;
- relieves inflammation;
- reduces capillary fragility;
- inhibits the formation of scars;
- eliminates allergy symptoms.
Recommendations for medical use and dosages:
- the drug must be used 2 times a day, 4 drops;
- the duration of the course of treatment is 1 week.
After using the solution, it is necessary to maintain the same body position for at least 1 minute so that the drug reaches the deep parts of the ear canal.
Floximed
Tsipromed is a drug in the form of ear drops, which can be replaced with an almost complete analogue with the same content of the active ingredient ciprofloxacin. The drug is produced by the pharmaceutical company E.I.P.I.Ko.
Pharmacological activity consists in antimicrobial action and suppression of the growth of pathological microorganisms that provoke the development of infectious diseases. The drug is intended for use in the treatment of eyes and ears without dividing into separate varieties.
Release form - drops of 5 ml in a plastic bottle with a dosing device. The active ingredient content of ciprofloxacin is 3 mg in 1 ml.
Main indications for medical use:
- inflammatory processes of the middle ear in acute otitis media;
- acute external and internal otitis media.
Also, the drug is used for ulcerative lesions of the cornea of the eye and for various infections of its appendages.
Application and dosage:
- for 1 application, 4 drops of the medicinal solution are recommended;
- frequency of use without additional turunda - 2 times a day;
- the duration of the drug use is 5-10 days.
In case of severe symptoms, it is allowed to lay thin cotton turundas, abundantly moistened with a solution of the drug, into the ear canal. During therapy, it is necessary to monitor the progress and response of the patient to its use. In the absence of improvement and, especially, if the state of health worsens, the course should be supplemented with systemic antibiotics in the form of capsules or tablets.
The drug Tsipromed is one of the main and widely used in the form of ear drops for the treatment of diseases of all parts of the ear. The price of the solution is relatively low, therefore, when prescribing such a drug, it is necessary follow the doctor's recommendations to avoid much more serious consequences in the absence of a prescribed treatment.
Video about drops Tsipromed
Review of ear drops Tsipromed:
