Polydexa ear drops. Price, instructions for use, analogues, reviews

Polydexa - ear drops, which effectively treat otitis media of infectious and bacterial etiology, as well as eczema of the ear canals. The drug is a combined product with an affordable price and a convenient form of release. The set with drops includes a dropper pipette, which makes it easier to use and dispense the drug in use.

Selling features

Polydexa - ear drops, the price of which does not exceed 300 rubles. The drug is approved for dispensing from pharmacies without a prescription. The volume of a bottle with ear drops is 10.5 ml and costs about 280-300 rubles. Polydex ear drops are a three-component agent, which includes: Polymyxin B, Neomycin and Dexamethasone. Outwardly, this tool is a light yellow or transparent liquid.

The quantitative ratio of the components of the drug is shown in the following table:

The name of the component of the drug	The amount of the component per 100 ml of the drug
Polymyxin B sulfate	1,000,000 units
Dexamethasone sodium metasulfobenzoate	100 mg
Neomycin sulfate	1 g

The preparation contains the following additional components: macrogol, citric acid monohydrate, thiomersal, purified water. The drug is available in the form of glass vials that contain 11 ml of the drug.

The vials are packed in cardboard boxes, and a special pipette is attached to the product.

Mechanism of work

Polydexa - ear drops, the price of which is determined by the cost of the components contained in this drug. The drug belongs to a group of agents that have antibacterial and anti-inflammatory effects on the ENT organs. Dexamethasone has an anti-inflammatory effect, and polymyxin, together with neomycin, has an antibacterial function.

Dexamethasone

This drug belongs to the group of glucoosteroid drugs. When applied externally, dexamethasone has a pronounced anti-inflammatory and anti-exudative effect. The component inhibits the reactions of macrophages and leukocytes and blocks the movement of leukocytes to the inflammation focus.

Due to the enhancing effect on the formation of lysosomal membranes, the accumulation of proteolytic enzymes decreases in the area of ​​inflammation. Due to the breakdown of histamine, the conductivity of the capillaries decreases. Dexamethasone inhibits the production of leukotrienes as well as prostaglandins.

An increase in phospholipase activity reduces the number of eosinophils and basophils, which also further reduces the growth of prostaglandins. An increase in the functional activity of gluconeogenesis enzymes occurs due to an increase in the kinematics of glycogen synthetase and the formation of glucose. The component inhibits the generation of antibodies, but does not reduce the amount of beta-endorphin.

Due to the suppression of glucose enveloping by fat cells, lipolysis is activated. As a result, the patient may experience some accumulation of fat as lipogenesis is stimulated due to the increased production of insulin.

Dexamethasone can negatively affect the normal growth of the body of children, since catabolic processes occur in muscles, lymphoid, adipose and bone tissues.

In this regard, long-term use of this remedy is not recommended. In case of an overdose with Dexamethasone, excessive activity of brain tissue and the occurrence of seizures may occur.

Dexamethasone is used for thyroiditis, Addison-Birmer disease, hypothyroidism, bronchial asthma, arthritis and connective tissue diseases, cerebral edema, leukemia, adrenal diseases, agranulocytosis.

In the practice of treating ear diseases, dexamethasone is used as an additional component in the treatment eczema of the ear canal and otitis media of the tympanic membrane, as well as other infectious diseases ENT organs.

Polymyxin B

A polypeptide-type antibiotic used in the treatment of infectious diseases of the ears, skin and eyes. The action of this antibiotic is based on blocking the membrane of the cytoplasm of bacterial cells, which leads to their destruction.

Polymyxin B is effective against the following bacteria: Shigella, Borderella pertussis, Escherichia coli, Klebsiella, Enterobacter, Salmonella, occidioides immitis, Vibrio cholera. The antibiotic can be used as a component in combination medicines as well as alone. It is excreted in the urine within 8 hours.

The use of Polymyxin B is contraindicated if there is damage to the tympanic membrane or too large skin lesions (with external use). Side effects include: dizziness, confusion, temporary blurred vision, difficulty breathing, hematuria, pruritus, proteinuria.

In case of impaired renal function, polymyxin B is not recommended.

Neomycin

An antibiotic that can be used both externally and internally. When applied externally, Neomycin is used for infectious diseases caused by such microorganisms such as: Proteus spp., Escherichia coli, Staphylococcus, Shigella spp., Streptococcus pneumonia. There is no antibiotic activity against pathogenic fungi and anaerobic bacteria.

The action of Neomycin is based on the destruction of ribosomes and the suppression of the formation of proteins in the cells of pathogenic bacteria. Among the side effects when using it, the following can be noted: rash, itching, nausea, diarrhea, ototoxic effect of hearing organs, nephrotoxic effect in the urinary system, impairment breathing.

The antibiotic should not be used for destructive conditions of the auditory nerve, impaired renal function and hypersensitivity to Neomycin. If you experience any allergic reactions or tinnitus during treatment with this drug, you should stop using it. Neomycin is excreted from the body within 3 hours, mainly by the kidneys.

Polydex, as a combined agent (Dexamethasone + Polymyxin B + Neomycin), has an anti-inflammatory and antimicrobial effect in infectious diseases of the hearing organs.

The use of Dexamethasone reduces inflammation of the outer ear, and the use of the antibiotics Neomycin and Polymyxin B neutralizes a wide range of pathogenic microorganisms that can be the causative agent diseases.

Who is the drug prescribed for?

Polydexa - ear drops, the price of which is not high in accordance with the therapeutic effects of the drug.

Polydexa is used for the following hearing diseases:

• Otitis externa with an integral structure (without microtrauma and cracks) of the tympanic membrane.
  
• Eczema of the external auditory canal caused by an infectious agent.

Who is prohibited

When using the drug, the following side reactions may occur:

• Hearing impairment in the presence of microcracks or trauma to the ear membrane (the cause is the toxic effect of the drug on the organs of the hearing aid)
• Allergic reactions, rash, itching.
• The onset of mycosis.

The drug should not be taken in the following cases:

• Hypersensitivity to polymyxin B or dexamethasone.
• Hypersensitivity to antibiotics of the amyoglycoside group (including neomycin).
• The presence of microcracks or other destructive conditions of the tympanic membrane.
• The presence of a viral infection of the ear canal.

Medication rules

Ear drops of Polydex are allowed to be taken by adults and children from 3 years old. The drug is instilled into each ear canal 2 times a day for a week. Dosage for adults: 1-4 drops in each ear. Dosage for children: 1-2 drops in each ear.

If the temperature of the drug is lower than body temperature, then an unpleasant sensation may occur when instilled. Therefore, it is recommended to warm the bottle with drops before use, for which you need to hold it in the palm of your hand for several minutes.

The procedure for using the drug is as follows:

1. Warm the bottle with the palms of your hands.
2. Open the bottle and draw up the product into a pipette.
3. Tilt your head and pull the auricle slightly.
4. Drop the required number of drops with a pipette (the exact dosage is prescribed by the doctor).
   
5. Do not move for 5-6 minutes so that the agent penetrates as much as possible into the ear canal.
6. Repeat the same procedure with the other ear.

After completing the course of treatment, the bottle with the remaining agent in it must be thrown away.

Interaction with other drugs

The drug should not be used in conjunction with amikacin, netilmicin, monomycin and streptomycin, due to the possible appearance of a pronounced ototoxic effect.

special instructions

Before using the drug, you must make sure that the eardrum is intact and there are no physical or infectious wounds on it. If the eardrum is damaged, the use of Polydex may impair the functioning of the hearing aid and cause hearing impairment.

If during the treatment with the drug there are any allergic reactions (especially in the form of a rash), you should stop using it. Do not use the product in conjunction with other topical preparations.

The drug should not be injected into the auricle under pressure, and during the instillation procedure, it is not allowed to touch the tip of the pipette with your hands (in order to exclude the introduction of infection). The drug should be stored at a temperature not exceeding 27 C. Shelf life is 3 years.

Substitutes

Polydexa - ear drops, the price of which depends on the constituent components. There are several analogues of the drug, which include all or only some of its components. In this regard, the price of analogs may be slightly lower or correspond to the price of Polydex.

Otipol

Ear drops containing neomycin sulfate, dexamethasone, and polymyxin B. Additional components: disodium phosphate dodecahydrate and sodium dihydrogen phosphate dihydrate are present. Drops are light yellow or transparent liquid. The drug is available in polyethylene bottles (5 ml) with a dropper dispenser.

This remedy is a combined drug and is used to treat otitis externa or eczema of the hearing organs of an infectious type. The drug can be used by adults and children from 4 years old. The course of treatment is 5 to 8 days. When prescribing the drug to children, the dosage should not exceed 2 drops, 2 times a day. Adults are prescribed no more than 4 drops, 2 times a day.

The exact amount of the drug is determined individually by the attending physician. Before performing the procedure, it is recommended to increase the temperature of the product in the bottle by holding it in a closed palm for several minutes. This is necessary to exclude unpleasant cold sensations when instilled into the ear. When instilling, the head should be slightly tilted to the side.

And after the agent reaches the ear membrane, after 5 minutes it is necessary to turn the head to the other side and drip the agent into the other ear in the same way. After instillation, a slight burning sensation in the ears may appear, and in rare cases, the appearance of various skin reactions is possible.

The drug should not be taken for neuritis, as well as if there are physical or infectious destruction of the tympanic membrane. The use of Otipol is contraindicated for pregnant women and for children under 3 years of age.

The price of the product corresponds to Polydex ear drops. Otipol can be dispensed over the counter without a prescription. The cost of this drug is approximately 250-300 rubles.

Anauran

Ear drops, composed of the following components: neomycin, lidocaine hydrochloride, and polymyxin B. The preparation contains additional components: glycerol, water, benzalkonium chloride. The drops are colorless and odorless. The drug is available in special bottles (25 ml) with a rubber dropper cap.

Anauran is used for chronic and acute otitis media, for purulent processes in the operated ear, as well as for non-perforated otitis media. Before each use of drops, it is necessary to heat the bottle, holding it in the palm of your hand for 3-5 minutes. After instillation in the ears, a slight burning sensation may occur, which disappears after a while.

The drug is instilled in 2-4 drops 3 times a day. The use of the drug for children is allowed after 4 years. The exact dosage and number of procedures are determined and prescribed by the attending physician. If during treatment with Anauran the action of the drug is not effective enough, treatment should be supplemented with additional antibiotics of the aminoglycoside group.

The drug is dispensed in pharmacies by prescription, and its cost is 240-260 rubles.

Neomycin

Universal drops that can be used to treat ear, nose and eye infections. The drops are light yellow or transparent in color. The drug is available in plastic bottles (5 ml) with a rubber dropper dispenser, packed in a cardboard box.

The presence of a broad-spectrum antibiotic (neomycin) has a successful antibacterial effect, and dexamethasone reduces inflammation in the area of ​​the ear or eye organs. The remedy successfully treats chronic and acute otitis media, as well as sinusitis and sinusitis of the nasal cavity. When treating the eyes, the drug is instilled no more than 2 drops into the lower eye area every 5 hours.

When the symptoms of the disease subside, the number of procedures per day should be gradually reduced until complete recovery. When treating ear otitis media, the drug is instilled no more than 3 drops into each ear 3-4 times a day. In the treatment of rhinitis and sinusitis, the drug is instilled no more than 3 drops into the nasal sinuses 3-4 times a day.

The exact number of drops required for treatment is determined by the attending physician. The course of drug treatment should not exceed 5 days. The drug can be used in patients of adults and adolescents (from 18 years old). As side effects when using the drug, allergic and skin reactions (itching, redness) may occur, as well as an increase in intraocular pressure.

The use of the drug is contraindicated in pregnant women, as well as during lactation. The drug is dispensed in pharmacies by prescription, and its cost is 230-250 rubles.

Polydexa - ear drops, produced in a convenient bottle, which have pronounced antibacterial and anti-inflammatory properties. The advantage of the drug is not only a wide spectrum of its action in the treatment of ear diseases, but also a reasonable price in pharmacies, taking into account its multicomponent composition.

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