Cyclopentolate eye drops. Price, instructions for use, reviews

For the complex treatment of ophthalmic diseases in traditional medicine drug is used Cyclopentolate. The drug is effective in combating pathologies of the anterior part of the eyeball. The components of the drug contribute to the dilation of the pupil, which is extremely important when carrying out diagnostic procedures.

Eye drops are highly effective and broad-spectrum. Affordable price allows using the drug for the complex treatment of keratitis and uveitis. But before buying a medicine, you need to consult with an ophthalmologist and study the instructions for use to make sure there are no contraindications.

Release form and composition of the drug

Cyclopentolate - eye drops (the price of the drug is justified by its effectiveness in the fight against inflammatory diseases of the visual system), which are produced in the form of a colorless solution. Cyclopentolate hydrochloride 10 mg is used as an active ingredient.

The positive therapeutic effect of the drug is enhanced by the following auxiliary components:

• Benzalkonium chloride.
• Distilled water.
• Sodium chloride.
• Disodium edetate (disodium salt of ethylenediaminetetraacetic acid).

The drug is sold in special dropper bottles of 5 ml. The medicine is packed in a cardboard box along with instructions for use.

Pharmacological properties

The active substance of the drug helps to achieve a blockade of M-cholinergic receptors, thereby reducing the intensity of the negative effect of the neurotransmitter acetylcholine on the patient's body. When used correctly, eye drops block cholinergic synapses that are located in the ciliary muscle and the sphincter of the eye pupil.

The components of the preparation easily penetrate into the deep tissues of the eye. The maximum concentration of the active substance in the patient's body is reached after 80 minutes. after applying eye drops. The pupil gradually dilates after 15-30 minutes. after instilling the medicine. Mydriasis persists for a maximum of 12 hours.

Cyclopentolate is characterized by a mild antispasmodic effect. The components of the drug reduce the intensity of the secretion of saliva, sweat, gastric and pancreatic juice.

Before using the drug, patients with hypertension should take into account that cyclopentolate hydrochloride increases the pressure inside the eye, increases the heart rate and can negatively affect the arterial pressure.

Pharmacodynamics and pharmacokinetics

The maximum cycloplegic effect appears after 20-80 minutes. after applying eye drops, mydriatic - after 25-65 minutes. The duration of exposure to the components of the drug on the visual system is 24 hours. Cyclopentolate in a minimal amount enters the patient's systemic circulation. The drug is excreted naturally (along with urine).

Indications for use

Cyclopentolate - eye drops (the price of the drug is affordable, which is very important for long-term treatment of inflammation of the iris and ciliary body of the eyeball), which have a wide spectrum of action and high efficiency in the fight against ophthalmic diseases of the inflammatory character.

The drug has the following indications for use:

• Preparing the patient for ophthalmic surgical intervention.
• Inflammatory diseases of the anterior part of the eye (for example, uveitis, keratitis, iridocyclitis, scleritis).
• Determination of true refraction in paralysis of the ciliary muscle.

Cyclopentolate is used in ophthalmology to prepare patients for refractometry or ophthalmoscopy. In microsurgery, the drug is used before cataract extraction.

The eye drops help block the cholinergic receptors in the optic organ. Due to this therapeutic effect, the circular muscles of the iris of the eye relax, the pupil expands. How long mydriasis will last depends on what dose of the drug was used.

The maximally dilated pupil does not react to light, so that ophthalmologists have the opportunity to examine the patient's fundus. After surgery, Cyclopentolate is prescribed to prevent inflammation.

Contraindications

Cyclopentolate can only be used after consultation with an ophthalmologist, as only a qualified doctor can prescribe a safe and effective therapy. Otherwise, there is a high probability of the development of adverse reactions, including punctate keratitis and a short-term decrease in accommodation.

In the annotation to the drug, the manufacturer indicated the following contraindications:

• Hypersensitivity of the body to the components of eye drops.
• Children's age (up to 3 months).
• Pregnancy.
• The period of breastfeeding the baby.
• Paralysis of the sphincter of the pupil, which occurs as a result of injury to the eye.
• The presence of a systemic reaction to the introduction of Atropine.
• Propensity to disrupt the natural outflow of intraocular fluid.
• Angle-closure glaucoma.

The drug is prescribed with caution to those patients who have been diagnosed with Down syndrome, intestinal obstruction or cerebral disorders. Cyclopentolate can be dangerous when the prostate gland is enlarged. The components of the drug with a probability of 85% provoke hypersensitivity in patients with light skin type and blue eyes.

At what age can the drug be used?

Cyclopentolate is approved for the treatment of ophthalmic diseases in children from 3 months of age. To determine the dosage and frequency of application of the drug, the child must undergo a medical examination. Therapy for ophthalmic diseases should be supervised by the attending physician.

Instructions for use, dosage

Before using the drug, you should wash your hands thoroughly to prevent infection of the mucous membrane of the eye. The procedure can be carried out without assistance. To do this, you need to sit on a chair and tilt your head back.

The drug must be instilled into the conjunctival sac by gently pulling down the lower eyelid with the index finger. After the end of the procedure, it is recommended to close your eyes several times so that the drug is evenly distributed over the tissues and sclera.

For the treatment of complicated uveitis or keratitis, ophthalmologists recommend every 4 hours. instill 1 drop of the solution into each conjunctival sac for 2 days. Only a doctor can prolong therapy, since self-medication is fraught with the progression of the disease and the development of concomitant pathologies.

For diagnostics

Before examining the visual system, the drug is instilled into the conjunctival sac 1-2 drops 3 times at regular intervals. The procedure is performed only by a qualified ophthalmologist, since he must control muscle accommodation.

In pediatrics

Under the supervision of the attending physician, Cyclopentolate is used to treat children from 3 months. Studies have shown that children under 1 year old with pronounced skin pigmentation are resistant to the negative effects of the drug. For the treatment of a child under 2 years of age, the concentration of the drug should be reduced to 0.5%.

To achieve a positive therapeutic effect, the solution is instilled 1 drop into each conjunctival sac. If necessary, the procedure can be repeated after 10 minutes. For the treatment of children from 2 years of age and older, the concentration of the drug can be increased to a maximum of 2%. In case of persistent or semi-permanent accommodation spasm, it is better to replace Cyclopentolate with Atropine.

To ensure functional rest of the eyes

Cyclopentolate - eye drops (the price of the drug is justified by its effectiveness in the fight against inflammatory disease the surface layer of the scleral membrane of the eye), which are used in ophthalmology to relax the ciliary muscles.

The drug is instilled in 1 drop 3 times a day. To ensure functional rest of the eyes in a complex inflammatory process, the drug can be used every 4 hours.

Side effects

Cyclopentolate is well tolerated by the patient's body in 98% of cases. The components of the eye drops in a minimum amount penetrate into the patient's systemic circulation, due to which the likelihood of deterioration in the work of internal organs is minimized.

Due to its high efficacy, good tolerability and affordable price, Cyclopentolate is in great demand in ophthalmology.

If the patient does not follow the treatment regimen recommended by the doctor, the patient may experience the following side effects:

• Central nervous system: auditory and visual hallucinations, discoordination, memory impairment, asthenia, ataxia, dizziness, increased anxiety, speech impairment.
• Local adverse reactions of an ophthalmic nature: redness of the conjunctiva, burning sensation in the eye, photophobia, increased intraocular pressure.
• Cardiovascular system: tachycardia, increase or decrease in blood pressure, dilation of blood vessels.
• In children under 12 years of age, Cyclopentolate can trigger the following symptoms: disorders, ataxia, speech impairment, memory loss, increased irritability, obsessive thoughts, insomnia.
• Organs of the gastrointestinal tract: intestinal obstruction, nausea, vomiting, decreased salivation, dry mouth, necrotic form of enterocolitis, stool disorder.
• Skin: burning and itching sensation, dermatitis, urticaria, increased dryness of the epidermis.
• Immune system: anaphylactic shock, pulmonary insufficiency.
• Urogenital system: false urge to urinate, decreased libido, difficulty urinating.

If any adverse reactions occur, the patient should stop using Cyclopentolate. For the treatment of diagnosed ophthalmic diseases, the patient should be assigned a safer analogue.

Overdose

The onset of overdose symptoms when using Cyclopentolate eye drops is possible only if the patient does not follow the treatment regimen prescribed by the ophthalmologist.

The manufacturer of the medicinal product does not exclude the likelihood of the following symptoms of overdose in the patient:

• Nausea, vomiting.
• Stool disorder.
• Increased body temperature.
• Chills.
• Dizziness.
• Migraine.
• Increased heart rate.
• Violation of mental reactions. The patient may be disturbed by disorientation in space, emotional excitement, and frequent mood swings.
• Dry mucous membranes and skin.

If the patient instills the drug Cyclopentolate into the nose, then with a probability of 95% paralysis of the respiratory muscles will occur, which will lead to the death of the patient. In this case, an effective antidote for eye drops is provided - Physostigmine.

For children, the dosage is 0.5 mg, for adults - 2 mg. If the level of toxic effects on the patient's body is high, then a repeated injection of Physostigmine will be required for 5 minutes.

To eliminate the symptoms of an overdose, it is forbidden to self-medicate. Only a qualified physician can prescribe effective symptomatic treatment after examining the patient.

special instructions

Cyclopentolate - eye drops (the price of the drug is justified by its effectiveness in the fight against ophthalmic diseases of the inflammatory character in adults and children older than 3 months), after the use of which a temporary decrease in visual acuity and general malaise. In 30% of patients, the drug causes short-term dizziness.

For this reason, during the course of therapy, it is recommended to refrain from driving a car and complex mechanisms that require increased concentration of attention. If the patient has photophobia, you need to protect your eyes from bright light and direct sunlight. Remove contact lenses before instilling the medicinal solution.

For the treatment of children, the dosage prescribed by the ophthalmologist must be strictly observed. After using the drug, you can feed the child only after 3-4 hours. Otherwise, Cyclopentolate may induce vomiting.

Laboratory studies have shown that the active substance of eye drops in a small amount penetrates the systemic circulation, and also passes through the placental barrier. The drug does not affect the formation of the fetus, but the risk of developing adverse reactions that can disrupt nutrition and reduce the supply of oxygen to the unborn child is not excluded.

Gynecologists do not recommend the use of Cyclopentolate during pregnancy and lactation. To combat diseases of the visual system, it is best to choose a drug with a safer composition.

Drug interactions

Sympathomimetics and alpha-adrenergic agonists can significantly enhance the effect of eye drops. In combination with M-cholinomimetics, the effectiveness of mydriatic is significantly reduced. Cyclopentolate negatively affects the action of those drugs that are intended for the treatment of glaucoma.

Cyclopentolate hydrochloride synergizes with phenylephrine. At the time of using the eye drops, it is recommended to abandon Pilocarpine, Carbachol and anticholinesterase agents.

Analogs

Cyclopentolate hydrochloride is a component of many medications. If there are contraindications to the use of cyclopentolate eye drops, the patient should consult an ophthalmologist to together with a specialist, select a safe analogue for dilating the pupil and complex treatment of visual diseases systems.

Drug name	Description
Cyclomed	The drug has an anticholinergic and mydriatic effect. Eye drops are used in the preoperative preparation of a patient when it is necessary to enlarge the pupil when removing a cataract. Cyclomed is included in the complex drug therapy of diseases of the anterior part of the eye: episcleritis, iridocyclitis, keratitis, uveitis, scleritis. The drug is effective in the study of refraction and ophthalmoscopy. Cyclomed is prohibited to use for glaucoma, paresis of the eye muscle, as well as with increased sensitivity of the body to the components of the drug. For the treatment of inflammatory diseases, Cyclomed should be instilled into each eye, 1 drop 3 times a day. For diagnostic procedures, it is recommended to use 3 drops with an exposure of 10 minutes.
Cycloptic	The drug is included in the complex drug therapy of inflammatory diseases of the visual system. Cycloptic is forbidden to use in the presence of the following diseases and conditions: angle-closure glaucoma, hypersensitivity of the body to components of the drug, children's age (up to 3 years), pregnancy and lactation, paralysis of the sphincter of the pupil after injury. For the treatment of eye pathologies, the drug is recommended to be instilled in 1 drop in the morning, at lunchtime and in the evening. For the study of refraction - 2 drops 3 times a day (with an interval of 15 minutes). For ophthalmoscopy, the drug is instilled into the conjunctival sac, 2 drops.
Tropicamide	The drug helps to overcome the pathology of the visual apparatus of an inflammatory nature, reduces the likelihood of developing synechia in the postoperative period. The drug is used for laser coagulation of the retina, as well as for the surgical treatment of the lens and vitreous body. Contraindications: glaucoma, hypersensitivity to the components of the eye drops. To dilate the pupil, you need to drop 1 drop of the solution into each conjunctival sac. When measuring refraction, use 1 drop of the drug 6 times with a break of 10 minutes.
Midriacil	The drug is prescribed to patients to determine refraction and fundus examination. Midriacil is included in the complex treatment of synechiae and inflammatory processes that affect the tissues of the visual system. Contraindications: hypersensitivity of the body to the components of the drug, glaucoma, children (up to 6 years). The treatment regimen is determined by the ophthalmologist, since everything depends on the patient's condition and the desired therapeutic effect.
Irifrin	These eye drops have the following indications for use: iridocyclitis, treatment of glaucocyclitic crises, pupil dilation before surgery, laser vision correction. Irifrin is prohibited to use in the presence of the following diseases: diabetes mellitus, glaucoma, hyperthyroidism, thyrotoxicosis, porphyria. For the manifestation of mydriasis, it is sufficient to install 1 drop of the drug into the conjunctival sac. For the treatment of true and false myopia, it is recommended to instill 1 drop of the solution before bedtime every 3 days for 1 month.

Before purchasing eye drops, the patient must undergo a medical examination so that the ophthalmologist can determine the diagnosis and prescribe safe drug therapy. Self-medication of eye diseases is fraught with a rapid decrease in visual acuity and the development of serious complications.

Terms, conditions of sale and storage

Cyclopentolate eye drops are sold only with a doctor's prescription. You can buy the drug online, as well as in a regular pharmacy. The shelf life of the medicinal product is 2 years. The contents of an open bottle can be used within 30 days.

At the end of this period, the unused medicinal solution must be disposed of. The drug should be stored in a dry, well-ventilated place, out of the reach of direct sunlight. The air temperature in the room should be between +15 and +25 C.

Price

The cost of Cyclopentolate eye drops varies from 480 to 750 rubles. When buying medicines on the Internet, you should choose only trusted points of sale in order to avoid counterfeit drugs. The final price of eye drops largely depends on the markup of the selected pharmacy chain and region.

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