Bromhexine (Bromhexine) tablets for children, adults. Instructions for use for cough, price, reviews

Bromhexine - it is a medical product intended for the treatment of various pathologies of the bronchi. The tablets can be used in both adults and children.

Forms of release and composition of the drug

This drug is produced in Russia in the form of tablets for oral administration. The main component of the drug is bromhexine hydrochloride.

Additional composition:

• milk sugar;
• corn starch;
• magnesium stearate;
• povidone K-25.

The drug is packed in plastic blisters with contour cells and packaged in cardboard containers.

Pharmacological properties

The drug has antitussive, secretomotor and secretolytic properties and belongs to the category of mucolytic drugs.

The action of the medication is aimed at reducing the viscosity of the secretory fluid that accumulates in the bronchi. This process is due to the content of polysaccharides in the preparation and its stimulating effect in relation to the cells of the mucous membranes of the bronchi responsible for the production and formation of secretory fluid (sputum).

It is assumed that the capsules take part in the formation of the surfactant.

Pharmacodynamics and pharmacokinetics

The drug has good absorption capacity and is rapidly absorbed from the gastrointestinal tract. When it enters the bloodstream through the liver, the agent undergoes metabolic processes.

Bioavailability is about 20%. The maximum level of the drug in the blood is noted after 1 hour. The components of the drug are distributed to almost all tissues and organs in the body.

From 85% to 90% of the agent leaves the body through the renal system along with urine. In this case, a greater number of components are excreted from the body in the form of metabolites. The main metabolite of the drug is ambroxol.

The components of the capsules enter into an active relationship with proteins. The half-life of the active substance is about 12 hours.

The drug is able to penetrate the blood-brain barrier. In this case, in small quantities, components can penetrate the placental barrier. Clearance may change in patients with severe functional disorders of the kidneys and liver.

Indications for use

Bromhexine - tablets for children, which are used in the treatment of pathologies of the respiratory system, which are accompanied by the formation of difficult-to-separate secretory fluid.

Indications:

• development of tracheobronchitis;
• chronic form of bronchitis, accompanied by obstructive disorders in the bronchi;
• bronchial asthma;
• pneumonia (chronic form);
• cystic fibrosis.

The tool is also indicated when carrying out diagnostic measures related to intrabronchial studies, as well as in the preoperative period. The drug can be used as a prophylaxis for the formation of sputum in the bronchial area.

Capsules can be used as an independent treatment, or as part of complex therapy.

Contraindications

The tablets have some limitations associated with the patient's condition and the effect of the main substance.

Contraindications:

• intolerance to the composition of the product (allergy to the drug);
• ulcers of the stomach and duodenum;
• the period of bearing or feeding the child;
• children's age up to 3 years;
• lactose intolerance, glucose-galactose malabsorption syndrome, lactase deficiency.

With extreme caution, medication can be prescribed in the following cases:

• the presence of bleeding in the stomach;
• bronchial pathologies due to increased accumulation of sputum;
• hemoptysis;
• kidney failure;
• liver failure.

In this group of patients, drug treatment is carried out only under the supervision of the treating pulmonologist.

At what age can the drug be used?

Bromhexine - tablets for children, which are indicated for use in childhood, starting from 3 years. In this case, therapy is carried out under the constant supervision of the treating pulmonologist or pediatrician.

Instructions for use, dosage

The dosage regimen depends on the form of the pathological process, as well as the age of the patient. In this case, the dosage can be adjusted by the attending physician, taking into account the patient's condition.

For children

The tablets are intended for oral administration. Take capsules with or without food. In children aged 3 to 6 years, the recommended dosage is 1 tablet 3 times a day.

Children from 6 to 10 years old and patients with a body weight deficit (less than 50 kg) are prescribed from 3 to 6 capsules per day. In this case, the dosage must be divided into 3 equal doses.

In children over 10 years of age, 6-12 tablets are prescribed per day. This number of capsules should also be divided into 3 equal parts. In most cases, the drug begins to show effectiveness after the first 3-6 days of therapy. The course of treatment is from 4 days to 4 weeks.

It should be borne in mind that for patients with impaired renal function, the dosage should be reduced. In this case, the interval between taking the capsules should be increased.

For adults

In an adult, 8 mg of the drug is prescribed. In this case, the received daily dosage must be divided into 3-4 equal doses. The drug begins to show effectiveness on the 4-6th day of treatment.

The duration of therapy should not exceed 4 weeks.

Side effects

In most cases, the drug is well tolerated by all groups of patients and does not cause negative effects. However, in rare cases, the agent can lead to the occurrence of adverse reactions associated with the action of the active component or the characteristics of the patient's body.

Side effects:

• Digestive system disorders: dyspeptic disorders, disorders in the production of hepatic transaminases - an increased amount.
• Failures from the central nervous system: the development of dizziness and headaches.
• Violations of the skin and subcutaneous tissue: rashes, hyperhidrosis.
• Respiratory disorders: coughing attacks, development of bronchospasm.
• Allergic reactions: urticaria, fever, angioedema, anaphylactic reactions.

In the event of adverse reactions, including unrecorded symptoms, it is necessary to consult a treating specialist for advice.

Overdose

If the doses prescribed by the doctor are exceeded, negative signs may develop.

Overdose:

• development of nausea and vomiting;
• diarrheal syndrome;
• various gastrointestinal disorders.

If such symptoms occur, it is necessary to cancel further taking capsules and consult a specialist. You may need gastric lavage. It is independently recommended to artificially induce vomiting and consume large amounts of water.

There is no specific antidote for intoxication.

special instructions

Bromhexine is administered orally only. The tablets are enteric and do not cause problems when taken. However, in some cases, it is allowed to pre-grind the capsule. This is necessary in case of problems with swallowing or when using the medication in childhood.

In the presence of ulcerative lesions of the stomach, as well as with signs of gastric bleeding, treatment with the drug should be carried out under the strict supervision of a specialist.

With extreme caution, the medicine must be used in patients with bronchial asthma.

With the use of the medication, in rare cases, the development of Stvens-Johnson and Lyell's disease was noted. In the event of such conditions or other allergic manifestations on the skin and mucous membranes shell, it is necessary to temporarily cancel further administration of the drug and contact the attending specialist for consultation.

The mucolytic properties of the drug are significantly increased when a sufficient amount of liquid is consumed during the entire period of therapy.

In childhood, treatment is carried out with additional massage actions that facilitate the removal of phlegm from the bronchi.

Tablets are prohibited from taking in the 1st trimester of pregnancy, since their components are able to penetrate the placental barrier. However, the use of the medication is allowed in the 2nd and 3rd trimester of pregnancy. At the same time, only the attending specialist should deal with the prescription of the drug during this period, taking into account the possible risks or benefits.

The drug does not have a negative effect on the psychomotor functions of a person, therefore it is allowed to drive a car or carry out other work that requires an increased concentration of attention. However, with the development of side effects, great care should be taken when carrying out these works, as well as when driving.

Drug interactions

It is forbidden to use capsules together with alkaline solutions.

The drug is not prescribed with other medicines, the action of which is aimed at suppressing the functions of the cough center. Such a combination can lead to a difficult discharge of the liquefied secretion, which will contribute to the accumulation of sputum in the lungs and cause additional complications that are dangerous to the patient's health.

Taking capsules and antibacterial agents together can lead to an enhanced effect of the second group of drugs. A similar effect is observed with the simultaneous use of the drug and the sulfanilamide group of funds. In this case, the components of other drugs can penetrate the secretory fluid, especially in the first few days of treatment.

The combination of tablets and non-steroidal anti-inflammatory drugs (NSAIDs) can contribute to the development of irritations in the gastrointestinal mucosa.

You should inform the attending specialist in advance about taking other medications during the appointment of Bromhexine.

Analogs

Bromhexine - tablets for children, which in some cases can lead to the development of hypersensitivity reactions. With the formation of such effects, it is necessary to cancel the further use of capsules and prescribe another drug that has a similar effect and indications.

Analogs:

• Ambroxol. This medicine is produced in the form of a syrup for oral administration. The main ingredient of the drug is the substance of the same name ambroxol. The drug belongs to the category of mucolytic and expectorant drugs. The active ingredient helps to enhance secretory motility in the bronchi and is used in the presence of the following pathologies: diseases of the respiratory system, which are accompanied by the formation of sputum - various forms of bronchitis, pneumonia, bronchial asthma, chronic obstructive pulmonary disease systems. The daily dosage is developed individually, based on the patient's age, and on average ranges from 15 to 30 mg per day. The duration of therapy is determined by a specialist in each case separately according to the severity and neglect of the pathological process. Contraindications to the use of syrup: 1st trimester of pregnancy, breastfeeding, allergy to the composition, fructose intolerance, children under 2 years of age. Terms of sale through pharmacies - over the counter. The cost of a bottle in Moscow pharmacies is from 450 rubles.
• Bronchorus. This drug is a domestic development produced in the form of enteric capsules or syrup for oral administration. The main ingredient of the drug is ambroxol, a substance that exhibits high mucolytic, secretory and expectorant properties. The medication is indicated in the treatment of the following diseases: acute or chronic forms of pathologies, accompanied by the formation of sputum in the bronchi - chronic obstructive pulmonary pathologies, bronchial asthma, pneumonia, the presence of bronchitis, bronchiectasis disease. In adults and children over 12 years of age, 1 capsule is prescribed daily 3 times a day. The duration of treatment is developed by the doctor individually. Restrictions on medication: children up to 12 years old (up to 12 years old, other dosage forms are used - syrup), 1st trimester of pregnancy, allergy to components, lactose intolerance. Terms of sale - no prescription. The prices for the medication vary between 20-30 rubles. per bottle.
• Bronchoxol. This medication is produced in Russia in the form of a solution for oral administration. The active substance of the agent is ambroxol. The action of this component is aimed at liquefying and removing sputum from the bronchi. The medicine is used in the treatment of pathologies of the respiratory system, which are accompanied by the formation of viscous sputum in the bronchi. Indications: bronchial asthma, bronchitis (chronic and acute form of the disease), chronic obstructive pulmonary tissue disease (COPD), the development of pneumonia, bronchiectasis pathology. The solution is taken orally after meals at 15-30 mg per day, depending on the age of the patient. The treatment is carried out within 1-4 weeks. In this case, the duration of the course is determined in each case individually and may vary depending on the patient's condition. Contraindications to taking syrup: presence of fructose intolerance, 1st trimester of pregnancy, children under 2 years of age, allergy to the composition of the medication. Vacation conditions - without a prescription. The price of syrup in regional and regional pharmacies ranges from 210 to 280 rubles. for the bottle.
• Lazolvan. This medication is manufactured at a Russian pharmaceutical plant in the form of a solution for ingestion or inhalation. The drug exhibits high mucolytic and secretomotor properties. A medicine is used in the treatment of diseases of the respiratory tract, which are accompanied by the formation of sputum (secretory fluid) in the bronchi. Indications for the administration of the solution: bronchial asthma, chronic obstructive pulmonary disease, pneumonia, bronchitis, bronchiectasis. In a day, in the form of inhalations, 1-2 injections are prescribed. In the form of an oral solution, the daily dosage varies from 1 to 4 ml 2-3 times a day, depending on the patient's age. Restrictions on the use of the medication: 1st trimester of pregnancy, breastfeeding, drug allergy. Dispensing from pharmacies is over-the-counter. The cost of a bottle in commercial and state pharmacies is from 249 rubles.

  

Bromhexine - tablets for children, which, with the development of intolerance reactions, should be replaced with similar drugs only with the permission of the attending specialist. Self-administration of analogs can lead to the development of complications or other negative consequences.

Terms, conditions of sale and storage

• The tablets should be stored in a dry and dark place at a temperature not exceeding 25⁰C.
• The shelf life of capsules is 5 years from the date of manufacture.
• Do not use the product after the expiration date indicated on the package.
• The drug is dispensed without a prescription.

Price

Prices for a medicine may vary depending on the place of sale and the distribution network of pharmacies. The cost is also influenced by the dispensed dosage form. You can find out the exact cost of a medicine at any public or private pharmacy located in the patient's place of residence.

Region / region	Form / dosage	Price
Moscow, Moscow region	Tablets for children, 4 mg	RUB 49-63
St. Petersburg	Tablets, 8 mg	RUB 54-65
Saint Petersburg (suburbs)	Drops, 20 ml	RUB 140-176
Leningrad region	Tablets, 8 mg	RUB 57-68
Novgorod region	Tablets for children, 4 mg	RUB 54-59

Before taking the capsules, you should consult with your attending pulmonologist and carefully study the annotation for the use of Bromhexine. Additionally, it is recommended to familiarize parents who have used the drug in therapy in children.

Video about Bromhexine tablets

Indications and instructions for Bromhexine tablets: