Dolobene gel. What heals, instructions for use, analogs are cheaper, reviews, price

Dolobene presents a popular gel, which is used externally to eliminate various symptoms of soft tissue pathologies.

The remedy treats diseases in the acute and chronic stages, but in most cases it is used to alleviate severe symptoms and prevent the development of complications. To get the maximum benefit from the drug, it is important to follow all the doctor's recommendations.

Indications for use

The tool is a gel for external use, which has anti-inflammatory, analgesic and decongestant properties. It is used for patients with various pathologies of soft tissues, spinal column, muscles. The medication is effective when it is necessary to provide first aid and in case of detection of chronic forms of the disease.

The main indications for prescribing a medicine:

• Contusions to the limbs or trunk. Accompanied by the appearance of hematomas in the affected area.
• Closed soft tissue injuries.
• Sprains of ligaments or muscles as a result of severe overstrain or during professional sports.
• Pathology of the spinal column, characterized by inflammation of the nerve roots.
• Mild osteoarthritis with pain on exertion.
• Arthritis and arthrosis of varying severity. It should be noted that the remedy is effective for the defeat of large joints. If the patient suffers from polyarthritis, the effectiveness is not so pronounced.
• Inflammation of the ligaments and tendons as a result of various injuries.
• Closed fractures without displacement. The drug is used as a first aid to relieve pain and prevent the formation of a large hematoma.
• Bursitis of various forms and severity. The drug helps to alleviate the course of pathology and prevents the development of a purulent process, provided it is used correctly.
• Contusions of the articular joints during a fall or during sports exertion.
• Neuritis and neuralgia, provoking discomfort from the skin, spreading to large areas of the body.

The remedy can be used for extensive hematomas that are accompanied by pain.

Compound

Dolobene gel treats various pathologies due to the content of several active ingredients in the composition. The main substance is dexpanthenol, which has pronounced regenerating, anti-edema properties.

Heparin in the composition of the product is also considered one of the main ingredients. It helps relieve swelling and eliminate hematoma in the affected area, prevents the formation of blood clots in the affected area and improves the condition of the vascular wall.

In addition, the product contains dimethyl sulfoxide. This ingredient has analgesic and anti-inflammatory properties and is therefore considered the most important ingredient.

The product contains auxiliary components:

• Rosemary and citronella oil.
• Cremophor.
• Trometamol.
• Polyacrylic acid.
• Water.
• Mountain pine oil.
• Small amount of isopropanol.

Auxiliary ingredients have no therapeutic effect. However, the presence of oils in the composition helps the active ingredients to better penetrate into deep tissues.

In what form is it produced

The drug can be found on pharmacy shelves only in the form of a gel for external use, which has a thick consistency, a pronounced coniferous aroma and a yellowish tint.

The gel is well absorbed into the skin, leaving an oily sheen and slight stickiness. The product is packaged in tubes of 100 g. Each tube is placed in a cardboard box, which also contains instructions that detail the rules for use.

There are also tubes of 50 g, but they are considered less in demand among patients. The cost of the medicine may differ depending on the volume of the tube, but the average price is 330-550 rubles.

Pharmacodynamics

Dolobene gel treats soft tissue and muscle pathologies almost immediately after application to the skin. Its active substances have a complex effect. Dexpanthenol affects the processes of regeneration and epithelialization, which allows you to accelerate recovery and stimulates tissue repair. As a result, the patient's condition improves rather quickly.

Heparin has an effect on blood cells, prevents platelets from sticking together, which helps to avoid the formation of blood clots.

Additionally, the ingredient has a positive effect on the vessels that are in the skin, helps prevent damage and the formation of hematomas. If the patient already has an extensive hematoma, the use of the gel can significantly reduce the recovery period for the normal color of the skin.

Additionally, heparin has an anti-edematous and anti-inflammatory effect, which makes it possible to improve the patient's condition almost immediately after application. The analgesic effect of the drug is achieved due to the presence of dimethyl sulfoxide in the composition. This ingredient acts on radicals that form during the development of the inflammatory process and provoke pain.

Suppression of the activity of these radicals leads to the elimination of severe symptoms. Even in the case when the pain does not completely disappear, it is significantly dulled, which improves the patient's condition.

The active substance also relieves swelling, has stimulating properties, and therefore helps to speed up the process of tissue repair. As a result, the use of the gel brings good results, even at an advanced stage of the pathological condition.

Pharmacokinetics

The drug is absorbed into the systemic circulation, despite being used only for the treatment of external tissues. Its active substances are distributed through the blood, and their maximum concentration is detected after 3 hours. For 12 hours, the concentration of ingredients in the blood does not decrease, which explains the high efficiency of the drug.

The accumulation of the active ingredient in the synovial fluid is noted with regular use for several days. In addition, the agent accumulates in the skin, which provides a long-lasting effect throughout the day. The active ingredients are processed in the liver, where they are broken down into metabolites.

The excretion of substances occurs over a long period. Some metabolites are completely evacuated within a week, others are excreted within 2 days. Most of the processed ingredients are evacuated by the urinary system. An insignificant part, which reaches 6%, is excreted with the help of the respiratory system.

The elimination period is somewhat prolonged in patients with kidney disease. It should be noted that with liver damage, the processing time also increases, which does not affect the therapeutic effect. In each case, the indicators may vary depending on the characteristics of the patient's body.

Application

Dolobene is used for different patients and for different disorders. The gel helps to cope with acute manifestations, and also treats some mild forms of soft tissue pathologies.

For children under 18

It is allowed to prescribe medication to patients over 5 years old in order to alleviate the condition with bruises, sprains and some other injuries. It is worth noting that the remedy is used only externally, and the scheme depends on the degree of neglect of the condition.

Illness or injury	Rules for using the medicine and dosage
Light bruises of soft tissues and muscles	With such lesions, the gel should be used no more than 2 times a day. It is applied in a thin layer and is easily rubbed into the skin until completely absorbed. It is better to repeat the procedure at regular intervals, which will ensure a uniform effect on the tissues throughout the day. The therapeutic course lasts up to 7 days. Usually this time is enough to obtain a pronounced result and prevent the development of complications.
Severe bruises with the formation of extensive hematomas	In case of severe bruises and other severe injuries, the agent is applied in a thin layer 3 times a day for 10 days. It is worth noting that the procedure must be carried out at regular intervals. You should not apply a thick layer of the product or carry out manipulation more often than the doctor prescribed. In most cases, the course is not extended, since this time is enough to get the result.
Sprains of ligaments, tendons and muscles, inflammation in these tissues	For sprains and other pathologies, the product is applied 3 to 4 times a day with a thin layer. The duration of the treatment course is 7-10 days. If necessary, the gel can be used for application under the bandage. This means that the agent is applied to the affected areas, after which a dry bandage is applied for 20-30 minutes. you can repeat the procedure no more than 1 time a day and no longer than 5 days in a row

It is not necessary to use the agent for application under the bandage on your own and without a doctor's prescription, since complications may develop. This method is usually indicated for the treatment of children from 8 years of age.

For adults

The drug is prescribed for adults without restrictions, but in the absence of contraindications. The tool is used in courses of 10 days. The agent is applied to the affected area with a thin layer, after which it is rubbed until absorbed. The procedure is repeated 4 times a day at regular intervals.

In addition, the medication can be used as a means to enhance the effectiveness of the electrophoresis procedure. To do this, before attaching the electrodes, a thin layer of gel is applied to the skin.

Low frequency electrical waves promote penetration of the agent particles into deep tissues, which leads to increased efficiency and a shorter recovery period. To obtain a pronounced result, the procedures are carried out 1 time in 2-3 days for 3-4 weeks. The specific number of sessions is determined by the doctor depending on the patient's condition.

For pregnant

The drug is contraindicated for use during lactation and childbearing. This is due to its active penetration into tissues and systemic circulation.

Experts suggest that the active substances can penetrate the placental barrier and enter breast milk, which is considered a lack of medicine. If it is necessary to use such funds, it is worth choosing a more effective medication.

For the elderly

Dolobene gel heals elderly patients rather quickly. There are no peculiarities of using the medicine in comparison with other patients. The drug is used according to the standard scheme, that is, it is applied in a thin layer 4 times a day for 10 days.

It can also be used under a dressing or during an electrophoresis procedure. However, such methods should be discussed with a doctor, and the dosage is also determined individually.

Contraindications

The tool is not used during pregnancy and lactation, as well as in case of intolerance to its active components and a tendency to allergic manifestations. If there are open infected wounds, cuts or cracks in the affected area, it is worth abandoning treatment until the integrity of the skin is restored.

A severe course of bronchial asthma is also considered a contraindication for prescribing a medication, which is associated with the excretion of a small proportion of substances through the respiratory system. With severe heart failure, coronary heart disease and angina pectoris in the acute stage, the drug is not prescribed.

Contraindications include an uncontrolled form of arterial hypertension, as well as hepatic and renal failure. It is strictly contraindicated to use the gel for treating the skin of patients under 5 years of age.

Relative contraindications include the recovery period after surgery on internal organs, internal bleeding of various origins and severity. In each case, it is better to pre-consult with a specialist before starting the course.

Overdose

Cases of drug overdose have not been recorded, since a small amount of the drug is absorbed into the systemic circulation. However, doctors suggest that treatment may trigger acute hives or Quincke's edema. In the first case, large spots appear on the skin. At the initial stage, they do not differ in color from the healthy skin, but they rise somewhat above its level.

When you scratch the spots, they turn red and the itching worsens. In this case, complications from the nose and eyes appear, manifested in the form of rhinitis and conjunctivitis of allergic origin.

With angioedema, a rash on the body may be absent, but the condition is aggravated by the development of edema of the mucous membranes of the throat. With a mild course of pathology, the condition improves after the termination of the use of the gel, but in advanced cases the help of a specialist is required, since suffocation is observed, which threatens the patient's life.

If symptoms of an overdose develop, you should stop using the gel and visit a doctor. In a hospital setting, the patient is assisted and the appropriate medications are prescribed.

Side effects

Dolobene gel treats various pathologies and tissues, but it can provoke complications if the instructions for use are violated. It is worth remembering that negative manifestations can appear even if all recommendations are followed.

The most common side effects are:

• Headache.
• Itching of the skin.
• Burning and peeling of the skin, the appearance of foci of irritation.
• Dizziness.
• Nausea and bouts of vomiting that do not relieve the condition.
• Frequent urination.
• Stool disorder, most often presenting as diarrhea.
• Disturbances from the respiratory system, manifested in the form of difficulty breathing.
• Chills and fever.
• Bad breath and plaque on the tongue.
• Thirst and loss of appetite, dryness of the mucous membranes of the mouth.
• Sleep disturbance, weakness and fatigue.
• Decreased mental and physical performance, strength and endurance.

Such complications are considered a reason for the immediate discontinuation of the drug. In the absence of improvement after discontinuation of the medication, it is important to visit a doctor who will prescribe symptomatic therapy.

Drug interactions

The drug does not affect the effectiveness of systemic medications, since it is absorbed in a small amount into the systemic circulation. However, doctors have found that the drug can enhance the effects of some non-steroidal anti-inflammatory drugs.

In addition, you should not prescribe the medicine in combination with other external agents containing the same active ingredients. The development of negative reactions is not observed when the drug is combined with vascular, antihypertensive and antibacterial drugs.

It is allowed to use it simultaneously with other systemic drugs. If the patient uses any remedy on an ongoing basis, it is worth consulting with the doctor in advance and getting his permission to combine the drugs.

Storage conditions and periods

The gel should be stored in its original packaging for 3 years. The production date is indicated on the packaging. It is prohibited to use the product after its expiration. During storage, it is important to limit access to children, as well as to direct sunlight. Do not freeze the medicine.

Conditions of dispensing from pharmacies

When purchasing a medication, you do not need to present a prescription from a doctor, which makes it easier to purchase, but increases the risk of complications when used alone.

Analogs

The drug has several analogues with similar medicinal properties. Most popular substitutes:

• Heparin ointment is considered the most affordable and popular analogue of the drug. Since it has decongestant, anti-inflammatory and anti-thrombotic properties. It helps to eliminate edema and hematoma in the affected area, prevents complications. The remedy is prescribed for bruises, vascular lesions for adults and children from 7 years old. The medication should be applied 2-3 times a day. Rub until absorbed, repeat for 5-10 days in a row.
• Hepatrombin - ointment and gel for external use. The product contains dexpanthenol and heparin, therefore it has a pronounced regenerating, anti-edema effect, eliminates hematomas and helps prevent the spread of the focus to healthy tissues. It is prescribed for adults and children from years of age with bruises, sprains, and other injuries. The medicine should be applied in a thin layer 2-3 times a day for 10 days. The product is considered very effective and is well absorbed. Its advantage is the presence of 2 form of release. For example, for compresses and during electrophoresis, an ointment is used that is not so quickly absorbed into the skin.
• Troxevasin Neo - a gel that also contains heparin and dexpanthenol, but additionally contains troxerutin. The combination of several components helps to eliminate puffiness, as well as improve the condition of blood vessels, and get rid of hematomas. The drug does not have an analgesic effect, therefore, it is more often prescribed for adults and children from 7 years of age with lesions of soft tissues with the formation of hematomas. The medicine should be applied 2 times a day in the morning and in the evening with a thin layer. The duration of the course is 7-14 days.

Analogues are not prescribed during pregnancy and lactation. Do not use them on your own without a doctor's prescription.

Dolobene is a popular and effective gel for external use that treats various pathologies of muscles, skin and articular joints. The tool can be used to treat children and adults, which is considered to be its advantage. When used correctly, side reactions are extremely rare, so it is important to follow all recommendations.

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