Belladonna candle extract. Reviews, instructions for use for hemorrhoids, pregnancy, constipation, price

Krasavki extract is a medicinal product plant-based, which is available in the form of suppositories for rectal administration. The active component of suppositories has pronounced anticholinergic properties. According to the reviews of patients who were treated with this drug, Krasavki extract has an anti-inflammatory and antispasmodic effect.

Indications for use

Candles Krasavka extract are indicated for use by people who suffer from chronic and acute hemorrhoids, or, according to the results of a diagnostic examination, they were found to have cracks in the posterior aisle.

The drug is actively used in practical proctology as the main means of therapy, as well as in combination with other medicines. Most of the reviews of patients who were treated with suppositories are positive.

Candles Krasavka extract have the following pharmacological properties:

• act as a local anesthetic, which is very important during an exacerbation of hemorrhoids or the formation of a deep fissure in the anus;
• have an anti-inflammatory effect, relieve swelling of damaged tissues and accelerate the process of their complete recovery (this pharmacological property of the drug is enhanced by the simultaneous administration of medications of the antiseptic spectrum actions);
• relieve spasm of smooth muscles, which is in a state of constant hypertonicity due to chronic pain syndrome and irritation of nerve endings;
• reduce intestinal motility, which also reduces pain and has a positive effect on the general well-being of the patient.

Krasavki extract - suppositories (reviews of the drug are 95% positive), which have a local effect without disrupting the function of internal organs located in the pelvic region. The medication is indicated for use only as rectal suppositories.

Compound

The table below shows the constituent components of the drug, and also describes their pharmacological purpose.

Active and auxiliary substances of the drug	Characterization of biochemical components
Belladonna extract	It is an active ingredient in suppositories that has a natural base. The composition of the juice of the medicinal plant belladonna contains a high level of alkaloids, which have a toxic effect. Their dosed use provides a local analgesic, antispasmodic and anti-inflammatory effect. The main extractant of belladonna is ethanol of 20% concentration. In terms of the total amount of alkaloids, the content of the basic substance in 1 suppository is 0.015 g.
Phenol	Phenol is an auxiliary component of suppositories that acts as a stabilizer and preservative. This substance prevents the chemical decomposition of the main component of suppositories during the storage period.
Solid fat	It is an excipient of the drug that forms the basis of rectal suppositories. In the production process of the drug, vegetable fats are used, which have undergone industrial processing and purification from harmful impurities.

Krasavki extract - suppositories (reviews of the medication indicate its high therapeutic efficiency), which have a natural biochemical composition, and also have a minimum amount side properties.

In what form is it produced

Krasavki extract is produced in the form of rectal suppositories, which have a creamy, white or a light brown shade, depending on the type of fat base used in the manufacturing process drug. The suppository manufacturer admits the presence of a slight plaque that forms on their surface during prolonged storage.

Suppositories Krasavka extract have a pronounced bullet-like shape, which allows the suppository to be administered quickly and with minimal discomfort. The preparation is packed in plastic blisters with 5 suppositories in each.

Candles are packed in a cardboard box, which is equipped with detailed instructions for the use of the medication. The average cost of the drug is from 22 to 39 rubles. for 10 suppositories.

Pharmacodynamics

Pharmacodynamic properties of Krasavka extract are due to the presence of alkaloids hyoscyamine, atropine, and also scopolamine, which are contained in belladonna.

These substances suppress the sensitivity of the nerve endings located in the pelvic region and directly in the area of ​​administration of the suppository. The conductivity of neural impulses, which are responsible for transmitting information about the presence of pain syndrome, is impaired. In combination with the analgesic effect, there is a decrease in the tone of the smooth muscles of the rectum.

The person does not experience feelings of acute pain and spasm, which are typical symptoms of hemorrhoids and anal fissures. Krasavki extract has a moderate anti-inflammatory effect, the manifestation of which is also due to the pharmacological properties of alkaloids.

The use of suppositories in short courses avoids the development of side effects that can be caused by the constituents of the belladonna substance. With prolonged therapy with suppositories, systemic absorption of the drug and the ingress of a small amount of alkaloids into the bloodstream are not excluded.

Pharmacokinetics

Pharmacokinetics of Krasavka extract is due to the local action of the active component of the suppositories. After rectal administration of the suppository into the rectal cavity under the influence of body temperature, the fatty base of the drug dissolves with the release of belladonna alkaloids.

These biochemical components penetrate the walls of the rectum and act on the nerve endings responsible for nerving the smooth muscles of the anus.

The antispasmodic and analgesic effect occurs after 10-15 minutes. after the introduction of the medication into the rectum. The average duration of action of the drug is from 6 to 10 hours, depending on the type and severity of the current disease.

To maintain a stable therapeutic effect, Krasavka extract suppositories should be used during a continuous therapeutic course, which is determined by the attending physician.

Application

Krasavki extract - suppositories (reviews of the drug indicate its excellent pain relievers and antispasmodic properties), which are used in the treatment of chronic hemorrhoids, as well as exacerbations this disease.

For children under 18

Suppositories based on belladonna alkaloids are indicated for use only in patients over 18 years of age. Krasavka extract is not used to treat children.

For adults

This drug is for rectal use only. The standard therapeutic dosage for adult men and women is 15 mg of the active substance (1 suppository) 2-3 times a day.

Step-by-step instructions for using candles are as follows:

1. Wash hands thoroughly with warm water and soap.
2. Lie on your left side with your hand under your head.
3. Open the blister with suppositories and remove 1 candle from it.
4. Bend your right leg at the knee and take it slightly to the side.
5. With unhurried and smooth movements, insert the rectal suppository into the anus so that the candle is located as deep as possible in the rectal cavity.

Over the next 15-20 minutes. it is recommended to be in a horizontal position so that the active substance of the drug has the maximum therapeutic effect.

The average duration of the treatment course with Krasavka extract suppositories is from 5 to 7 days. Depending on the type and severity of the disease, the duration of the use of suppositories can be extended by the attending physician. The maximum daily dosage of the drug is 150 mg of the active substance (no more than 10 suppositories).

For pregnant

Krasavki extract - suppositories (reviews of the drug are mostly positive), which can be prescribed to pregnant women and breastfeeding children, but only as a last resort. The attending physician weighs all the potential risks to the developing fetus and the expected therapeutic effect.

Only after that a decision is made on the use of these suppositories. The dosage of the medicinal product is also calculated on an individual basis. Taking into account the state of pregnancy, the standard adult dose of the medication can be reduced by 2 times.

For the elderly

Elderly patients are prescribed the introduction of 1 suppository 2-3 times a day. In this case, the attending physician takes into account the presence of concomitant diseases and age-related changes in the work of internal organs. Krasavka extract suppositories are used for 1 week. In the absence of a therapeutic effect, it is recommended to consult your doctor.

Contraindications

The drug is contraindicated for use in patients of all age groups who have the following diseases and pathological conditions of the body:

• thyrotoxicosis of the thyroid gland, as well as other organ pathologies associated with a violation of its secretory activity;
• inflammatory and ulcerative diseases of the gastrointestinal tract;
• congenital or acquired glaucoma;
• coronary heart disease;
• tachycardia and mitral stenosis;
• flickering arrhythmia;
• chronic heart failure;
• diseases of the genitourinary system that cause acute urinary retention;
• intestinal obstruction;
• the presence of internal bleeding or a high probability of its occurrence;
• a tendency to allergic reactions to belladonna alkaloids, as well as auxiliary components of the drug.

Before using Krasavka extract suppositories, the patient must undergo a comprehensive examination, according to the results of which other pathologies can be detected, excluding the possibility of using this drug.

At the same time, the manufacturer of the medication focuses on the fact that rectal candles of this type are used with caution in relation to patients with the following pathologies:

• benign prostatic hyperplasia;
• Down syndrome;
• cerebral palsy;
• obstructive processes inside the urethra;
• renal or hepatic failure (it does not matter the disease develops in an acute or chronic form of the course);
• ulcerative colitis, as well as Crohn's disease;
• all types of lung diseases;
• traumatic brain injury;
• autonomic neuropathy;
• hernia of the esophagus.

In patients with similar diseases, the risk of developing side effects caused by the action of the active substance of Krasavka extract suppositories increases.

Overdose

The occurrence of an overdose of a drug is possible in the event of a violation of the rules for using the drug.

In this case, the patient develops the following symptoms of general body poisoning:

• severe nausea and vomiting;
• headache;
• physical weakness, which is accompanied by a drowsy state;
• a rapid decrease in blood pressure;
• suppression of the functions of the central nervous system, which may be accompanied by auditory and visual hallucinations;
• a decrease in the activity of the centers of the brain responsible for maintaining the stable work of the heart, blood vessels and respiratory organs (in this regard, a person may experience a feeling of lack of air, bronchial spasm);
• sleeplessness at night;
• tremor of the upper limbs;
• increased agitation, unstable psychoemotional state, rapid mood swings.

Patients with signs of an overdose with Krasavka extract suppositories are shown to use symptomatic therapy. Patients are prescribed injection of drugs from the pharmacological group of cholinomimetics.

If necessary, other medications can be used, the spectrum of which is aimed at reducing the signs of intoxication of the body (sorbent preparations, sodium chloride solution).

Side effects

Despite the fact that rectal suppositories of this type are well tolerated by most patients of all age groups, the occurrence of the following side effects is not excluded:

• disturbances in the work of taste buds (the food consumed may seem too sour, salty or bitter);
• a constant feeling of thirst, which can only be quenched for a short period of time;
• decreased intestinal motility;
• dysfunction of smooth muscles, which is responsible for the tone of the muscles of the gallbladder, as well as the bile ducts;
• dryness of the mucous membranes of the mouth;
• acute urinary retention, which most often occurs in people initially suffering from organ diseases excretory system and genital area (urolithiasis, urethral obstruction, prostatic hyperplasia in men);
• manifestation of myocardial ischemia;
• various violations of the heart rhythm, which may be accompanied by attacks of tachycardia, angina pectoris or bradycardia;
• attacks of severe headache;
• redness of the face and feeling of heat;
• dizziness (short-term lack of coordination of movements is not excluded);
• increased intracranial pressure;
• dilated pupils;
• decreased secretory activity of the bronchial tree;
• the formation in the organs of the respiratory system of thick sputum, which is poorly evacuated during a cough;
• urticaria, rashes and itching of the skin surface, edema of epithelial tissue, which are of an allergic nature;
• anaphylactic shock (this side effect of the medication can be fatal);
• increased dryness of the skin caused by a decrease in the functions of the sweat and sebaceous glands.

In case of manifestation of side effects of suppositories, further therapy with the drug should be discontinued, as well as consult the attending proctologist. In the process of treatment with Krasavka extract candles, one should take into account the fact that the active substance of the drug can reduce psychoemotional reactions and the functions of the central nervous system.

Therefore, it is recommended to temporarily refrain from driving vehicles, equipment and mechanisms that require increased attention.

Drug interactions

The active substance of Krasavka candles extract enters into drug interaction with drugs of the following types:

• monoamine oxidase inhibitors - cause cardiac arrhythmias;
• Quinidine and Novocainamide - the antispasmodic and analgesic effect of belladonna alkaloids is enhanced;
• drugs from the opiate group - suppositories reduce the analgesic properties of narcotic drugs;
• Diphenhydramine and Diprazin - the therapeutic effect of Krasavka extract becomes more pronounced;
• Haloperidol and drugs from the corticosteroid category - increase intracranial pressure;
• Sertraline - the patient experiences a depressive state and depression of psychoemotional reactions;
• antibacterial drugs from the category of penicillins - enhances the therapeutic effect of suppositories and antibiotics;
• sulfa drugs - the risk of kidney damage increases with the further development of intoxication of the body;
• potassium-based drugs and anti-inflammatory nonsteroidal drugs - there is a risk of ulcerative formations in the intestines, which can lead to internal bleeding.

All of the above features of the drug interaction of Krasavka extract should be taken into account when prescribing suppositories in combination with medicines from other pharmacological groups. Especially if the patient is undergoing a course of complex therapy.

Storage conditions and periods

Candles Krasavka extract should be stored out of the reach of children at an air temperature not higher than +25 degrees Celsius. The drug should be placed away from direct sunlight. The shelf life of the medication is 3 years, after which the further use of suppositories is prohibited.

Conditions of dispensing from pharmacies

The drug is dispensed without a prescription. You can buy the drug at a pharmacy or on the Internet.

Analogs

The following drugs are presented on the pharmaceutical market, which are analogs Beauty extract, used to treat hemorrhoids and anal fissures:

• Anusole - these are rectal suppositories based on belladonna extract, which have an antispasmodic effect, and are assigned to receive 1 suppository from 2 to 3 times a day (the average cost of a medication is 70 rubles);
• Belladonna extract - these are anti-inflammatory and analgesic suppositories, which are indicated for admission in case of exacerbation of hemorrhoids and lesions of the rectum (the optimal dosage of the drug is 1 candle, which is inserted into the anus 2-3 times a day, and the price of the drug is is 38 rubles);
• Betiol Are rectal suppositories that are made on the basis of ammonium salt and belladonna extract (prescribed for rectal administration, 1 suppository up to 3 times a day, and the cost of the medication is pharmacies 42 rubles);
• Hemorrhoids Is a combined medicinal product, the active components of which are extracts of chamomile, sarotamnus, belladonna, yarrow ordinary (anti-inflammatory and antispasmodic agent is prescribed 1 candle 2-3 times a day, and the average price of suppositories is 55 rub.).

Candle Krasavki extract is an effective drug for the treatment of hemorrhoids and anal fissures. Suppositories have a pronounced antispasmodic, analgesic and anti-inflammatory effect, which is confirmed by positive patient reviews.

The drug is used exclusively for rectal administration into the rectal cavity. Krasavki extract can be used as part of complex therapy, or as an independent preparation. The medication is prescribed for the introduction of 1 suppository 2-3 times a day. The duration of the therapeutic course should not exceed 7 days.

Video about candles with belladonna extract

Candles with belladonna for hemorrhoids: