Claritin tablets. Price, instructions for use, what helps, analogs, reviews

Claritin is a medicinal antihistamine spectrum drug action, which is available in the form of tablets and flavored syrup. The medication is used to treat adults and children prone to allergic reactions. In retail pharmacy chains, the average price of Claritin varies from 216 to 230 rubles. per packing.

Indications for use

Claritin tablets are an antiallergic drug that is used for symptomatic or course therapy of allergic reactions.

The appointment of the drug is carried out by an allergist or therapist, depending on the clinical manifestations of the disease. A distinctive feature of the drug is that it has a high degree of effectiveness, and also has an affordable price.

Claritin is indicated for use in the following cases:

• relief of symptoms of adenoviral conjunctivitis in children and adults of all age groups;
• urticaria of allergic etiology;
• all manifestations of contact dermatitis, which are caused by a negative reaction to external stimuli the environment (wild plants, pet hair, water containing chemicals, pollen);
• elimination of the negative consequences associated with the bites of poisonous insects (bees, wasps, hornets, ants);

  

• rashes of the skin surface, which are an allergic reaction to food, synthetic fibers of clothing, drinks, detergents and cosmetics;
• incessant itching of the mucous membranes and epithelial tissues of the body, which is of an allergic nature of origin.
• prevention of angioedema in the presence of a real risk of developing an acute allergic reaction;
• bronchial asthma, the attacks of which occur as a critical amount of allergens accumulates in the patient's blood;
• seasonal allergic rhinitis (in this case, the drug is used as a drug for symptomatic therapy).

Claritin can be used as an additional agent in the complex treatment of other diseases, signs of which are severe itching of the skin, multiple rashes and edema of epithelial fabrics.

The drug has the following pharmacological properties:

• relieves swelling of the mucous membranes of the nasopharynx, larynx, lower respiratory system;
• has an antihistamine effect, suppressing the sensitivity of receptors that are involved in the development of an acute allergic reaction;
• prevents the occurrence of bronchial spasm caused by the pathogenic effects of allergens;
• eliminates the signs of allergic rhinitis, itching of the skin, rashes, urticaria.

The maximum therapeutic properties of the drug Claritin are manifested under the condition of its regular intake and maintenance of the optimal concentration of the active component of the antihistamine in the blood.

Compound

Claritin is an effective drug that has a simple biochemical composition with a minimum amount of auxiliary components. The table below describes in detail the main and additional substances of this medication.

The composition of the drug Claritin	Pharmacological purpose of components
Loratadin	This is the active substance of the drug Claritin, the concentration of which is 10 mg in 1 tablet. Loratadine has pronounced antihistaminic properties, the presence of which allows you to successfully fight the manifestations of all types of allergic reactions.
Magnesium stearate	This is an auxiliary component of the drug, which is used as an anti-caking agent. Magnesium stearate allows you to preserve the dense structure of the tablets, preventing their premature destruction in warehouse storage conditions.
Lactose monohydrate	It is a Claritin excipient that acts as a natural preservative. Lactose monohydrate is a milk sugar that prevents chemical breakdown of the main component of Claritin. This substance is contraindicated in people who have individual lactose intolerance. This aspect should be taken into account when prescribing the drug.
Corn starch	This is an auxiliary component of an antihistamine, which is part of the protective shell of the tablets. Corn starch is a completely safe substance that is broken down in the organs of the gastrointestinal tract.

Before starting therapy with Claritin, it is recommended to familiarize yourself with the composition of the drug in detail, to make sure that the main and auxiliary substances of the drug are tolerated by the body. Prior consultation with an allergist or therapist is a prerequisite.

In what form is it produced

Claritin is produced in 2 main forms. These are round tablets with a dosage of the active substance of 10 mg, which are packed in plastic blisters of 10 tablets. in everyone. The main package of the medication is a cardboard box, inside which contains detailed instructions for the use of the medication.

Another form of drug release is a thick syrup with a pleasant peach aroma. In this case, the mass fraction of the main component is 1 mg in 1 ml of the drug. The syrup is poured into glass bottles with a capacity of 60 ml, and packed in cardboard boxes.

Pharmacodynamics

Claritin tablets (the price of the drug is affordable for most consumers) refers to the pharmacological group of tricyclic antihistamines, which have selective activity against to H1 receptors.

The pharmacodynamic feature of the drug is that if the recommended dosage is observed, sedation and suppression of psychoemotional reactions do not develop. Claritin does not interfere with the absorption of norepinephrine and does not adversely affect the function of the cardiovascular system.

Clinical studies with the introduction of skin tests for sensitivity to histamine showed that when using 10 mg of loratadine, the therapeutic effect occurred already after 1 hour. The maximum concentration of the active substance in the blood serum was recorded after 8 hours from the start of taking the drug.

The preservation of the pharmacological properties of Claritin continues over the next 24 hours. Taking the medication for 28 days does not cause addiction of histamine receptors in relation to loratadine.

Laboratory studies of the pharmacokinetic properties of the drug showed that the active substance Claritin is rapidly absorbed into the intestinal wall, spreads throughout the body and binds to blood proteins. The use of the medication with food may lead to a slower absorption of loratadine, but in general this does not affect the final therapeutic effect.

The metabolism of the antihistamine occurs in the liver tissues, and its half-life is 1-2 hours. The main metabolite of Claritin is the substance desloratadine, which is considered pharmacologically active and is responsible for the onset of the therapeutic effect.

Claritin tablets (the price of the medication ranges from 216 to 230 rubles) must be taken during the therapeutic course established by the doctor. After the half-life is over, about 40% of the drug's metabolites are excreted in the urine, and 42% of the substances are utilized in the feces.

The average duration of complete cleansing of tissues from Claritin is 10 days. In patients with impaired renal and liver function, the half-life of the drug lasts 2 times longer. The use of the hemodialysis procedure for artificial blood purification does not affect the pharmacokinetics of loratadine, as well as its main metabolites.

Application

Claritin is taken orally, regardless of the meal schedule. The final dosage is determined by the attending physician individually, depending on the patient's age, the severity of the allergic reaction and the presence of concomitant diseases.

For children under 18

The drug is approved for use in children who have reached the age of 2 years. A child weighing over 30 kg should take 1 tablet of medication 1 time per day. The drug should be drunk at the same time of the day so that the maximum concentration of the active substance is maintained in the blood serum.

Children weighing less than 30 kg should drink syrup. Taking an antihistamine should be accompanied by plenty of drinking. Children of the younger age group perform crushing of the tablet until a powdery mass is formed.

For adults

Claritin tablets (the price of the drug is at an average level) is prescribed for the treatment of adult men and women suffering from allergic reactions. The antihistamine is taken 1 tablet 1 time per day. This dosage is indicated for adult patients and children over 12 years of age. You can take the medication before meals, during or after a meal. The tablet should be swallowed with a sufficient amount of liquid.

For pregnant

Claritin is not recommended for women who are pregnant or breastfeeding. Restrictions on the use of the drug are associated with the fact that its metabolites are able to overcome the placental barrier and penetrate into breast milk.

The influence of loratadine can negatively affect the development of the child, the functional activity of the internal organs.

For the elderly

Claritin is approved for use by elderly patients, but before prescribing the drug, the patient must undergo a comprehensive examination of the body. For people with severe liver pathologies, the final dosage of the medication should be adjusted by the attending physician.

In most cases, it is reduced to 5 mg per day (half a tablet). In this case, the patient is under constant supervision of medical personnel. The presence of kidney disease does not require a change in the dosage of Claritin. Patients in satisfactory health should take 1 tablet of the drug 1 time per day. The meal schedule doesn't matter.

Contraindications

Claritin tablets (the price of the medication depends on the factors of the internal and external market) are contraindicated for admission to people who have an individual intolerance to the main or auxiliary components drug.

In this case, an aggravation of an allergic reaction may occur with the development of severe consequences in the form of anaphylactic shock, edema of the mucous membrane of the larynx, nasopharynx. Patients who are lactose intolerant should also refuse therapy with Claritin.

Overdose

In case of an overdose of Claritin, the patient may experience symptoms of general intoxication of the body, which are manifested by the following conditions:

• nausea and vomiting;
• dizziness;
• decrease in blood pressure indicators;
• heart palpitations, as well as other heart rhythm disturbances;
• attacks of severe headache;
• loss of appetite;
• an upset bowel movement, which is most often accompanied by diarrhea;
• excessive dryness of the oral mucosa;
• dehydration of the body caused by frequent urge to defecate;
• allergic reactions in the form of urticaria, red rash, edema of mucous membranes, itching of epithelial tissues.

The main danger of an overdose with Claritin is that its active substance, loratadine, is not excreted from the body using hemodialysis. As measures of emergency medical care, gastric lavage and sorbent preparations are used.

In this case, Activated carbon can be used in an amount of 5 to 10 tablets, Enterosgel (at least 1-2 tbsp. l.), Atoxil, 1 sachet of which is dissolved in 200 ml of warm water.

Before the arrival of an ambulance, the patient should be in a horizontal position, provide himself with plenty of drink, so that natural gastric lavage is carried out. Over the next 3 days, the person must be under medical supervision.

Side effects

Clinical studies of the drug have shown that the antihistamine is well tolerated by patients of all age groups.

The risk of side effects is minimal, but they can still manifest with the following symptoms:

• headache, which can only be eliminated with the help of potent pain relievers;
• cramps of the lower extremities;
• dizziness and lack of coordination of movements;
• tachycardia attacks and other disruptions in the rhythmic activity of the heart (the manufacturer of the drug emphasizes attention to the fact that the side properties of Claritin rarely affect the cardiovascular system);
• a feeling of constant dryness in the oral cavity, which cannot be eliminated with the help of copious drinking;
• nausea and loss of appetite;
• an acute allergic reaction in the form of anaphylactic shock with edema of the laryngeal mucosa and an attack of suffocation (this is the most severe side effect of the drug, which can lead to of death);
• inflammation of the walls of the stomach;
• a decrease in the functional activity of the liver tissues (pathological changes in the functioning of the organ are reversible, and their recovery occurs after the complete cessation of Claritin);
• rapid body fatigue and general weakness;
• the appearance of a red rash, which is localized on the skin surface of the abdomen, limbs, back, neck (this is one of the forms of an allergic reaction, but in a milder form of its manifestation).

Unlike most other antiallergic medicines with a tablet form of release this drug does not affect the reaction rate, does not cause drowsiness or decreased concentration attention.

The presence of side effects that have arisen after taking Claritin requires the termination of further drug therapy. It is recommended that you contact your attending allergist or therapist so that the specialist selects an antihistamine based on another active substance.

Drug interactions

Clinical studies of the drug have shown that the simultaneous therapy with Claritin and the intake of alcoholic beverages does not affect the concentration of loratadine in the blood serum. At the same time, this negatively affects the functions of the liver, which is experiencing additional stress.

Taking Erythromycin, Cimetidine and Ketoconazole increases the level of the active substance of the drug, and also slows down its half-life. The simultaneous use of Claritin and inhibitors of CYP 2D6, as well as CYP 3A4 led to an increase in the concentration of loratadine.

In the latter case, the risk of overdose and the development of adverse reactions increases. With drugs of other pharmacological groups, the antihistamine does not enter into chemical reactions. All clinical studies of drug interactions of Claritin were conducted in adult patients. There are no data on the reactions of the child's body.

Storage conditions and periods

Storage of the medicinal product should be carried out in the original packaging of the manufacturer at an ambient temperature not higher than +25 degrees Celsius. The medication must be left out of the reach of children.

The surface of the Claritin package must not be exposed to direct sunlight. If these conditions are met, the shelf life of the tablets is 4 years, after which further use of the drug is prohibited.

Conditions of dispensing from pharmacies

To buy the antihistamine Claritin, you do not need a special prescription from your doctor.

Analogs

A large number of antihistamines are presented on the pharmaceutical market, which have identical properties, and also contain the active substance loratadine in their composition. The table below lists medicines that are analogous to Claritin tablets.

Drug name	Characteristics of the medicinal product
Aleric	Allergy tablets with a dosage of 10 mg loratadine. Produced in plastic blisters of 7 and 30 tablets. The country of origin of the medication is Poland. Aleric is prescribed to take 1 tablet 1 time per day. The average cost of the drug is 250 rubles.
Erolyn	A broad-spectrum antihistamine with a dosage of 10 mg loratadine. The drug is produced in Hungary. It is prescribed to take 1 tablet per day. People with impaired liver function take half of the indicated dose. Erolin's price is 245 rubles.
Lorano	Antiallergic drug based on loratadine. The dosage of the active substance is 10 mg. It is indicated for taking 1 tablet 1 time per day at the same time. The diet does not matter and does not affect the absorption of the medication. The drug is produced in Poland, and its average cost is 255 rubles.
Loratadin	The Russian analogue of the drug Claritin, which contains 10 mg of the active substance. An antihistamine is prescribed for taking 1 tablet 1 time per day. The course of therapy is determined individually, depending on the type and severity of the allergic reaction. In pharmacies, the average price of a blister of 10 tablets is 29 rubles. For a package of Loratadin, which contains 30 tablets, you will have to pay about 86 rubles. The drug is produced by the pharmaceutical company Ozone LLC.

Claritin is an effective antihistamine for the treatment of all types of allergies. The medication can be used for children who have reached the age of 2 years and older.

The main component of the drug is the active substance loratadine. Claritin is produced in two main dosage forms, which are tablets and a syrup with a pleasant peach flavor.

The drug is contraindicated in patients with individual intolerance to loratadine and lactose. To buy a drug, a doctor's prescription is not required, and in pharmacies its average price ranges from 216 to 230 rubles. per packing.

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