Riboflavin tablets. Price, instructions for use, where to buy, reviews

For the normal functioning of the body needs vitamins. If an insufficient amount of them comes with food, then they are taken in tablets. One of these vitamins is Riboflavin (Vitamin B2), the price of which is affordable for people with different material incomes.

Indications for use

Riboflavin is a yellowish tablet with a flat cylindrical shape with a notch. A small amount of dark blotches is allowed on the tablets. This remedy belongs to the vitamins of group B (B2), necessary for the human body and having wide indications.

Vitamin B2 is recommended for those who have:

• wounds and ulcers that do not heal for a long time;
• skin problems (eczema, flaking);
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• deterioration in the quality of vision in the evening;
• vision problems (inflammation of the iris, conjunctivitis, corneal ulcer);
• radiation sickness;
• keratitis;
• viral hepatitis A;
• liver problems;
• disruption of the intestines;
• Iron-deficiency anemia.

The biological function of this vitamin preparation is that it, as a coenzyme, is part of many vital redox enzymes.

Riboflavin gives the human body vital energy, promotes normal metabolism and provides oxygen to organ cells. If the body is not deficient in this Vitamin, many diseases can be avoided.

Compound

The main active ingredient of these tablets is riboflavin (1 tablet contains 2 mg). He participates in the regulation of redox processes and metabolism, which is important at any age.

The rest of the components (auxiliary) perform equally important roles. This is a potato starch that provides the necessary consistency in the production of many medicines.

A chemical such as calcium stearate is also present in Riboflavin as a lubricant that can absorb moisture from the air and affect the strength of the tablets. It does not dissolve in water.

Another component is talc, which serves as an additional source of silicon and magnesium and is completely decomposed in the digestive system. Powdered sugar in the composition of the drug is necessary to create the shell of the tablets.

In what form is it produced

Riboflavin is available in the following dosage forms: tablets, powder, capsules and ampoules. Dosage in powder - 0.002 g (used for prophylactic purposes), and in tablets - 2 mg, 5 mg, 10 mg (for treatment). The package contains 50 bags of powder or 50 tablets (in a can or a cell package). Ampoules contain 1 ml of substance for intramuscular administration.

The jar can contain 10, 20 or 25 tablets per pack. Instructions are attached to the medicine. Riboflavin capsules are sold at prices ranging from 450 to 938 rubles. The bottle contains 100 capsules.

Riboflavin tablets, the price of which ranges from 733 to 1570 rubles. for 100 pcs., can be bought at any pharmacy. Vitamin B2 in ampoules is sold at a price of up to 94 rubles.

Pharmacodynamics

Riboflavin (Vitamin B2) is a vital component of the human body. With its help, red blood cells are formed - erythrocytes, as well as antibodies that are needed for normal human growth and the regulation of reproductive functions.

Without vitamin B2, a person's hair grows poorly and falls out, nails exfoliate, dry unhealthy skin, and the thyroid gland is disrupted and the genitals develop poorly.

Outwardly, it looks like this: cracks appear on the lips of a person with a lack of this vitamin, peels off epithelium, the mucous membrane of the lips is affected, places of inflammation are formed in the corners of the mouth (angular stomatitis). The tongue may be swollen, reddened. The nasolabial fold, nose, ears, and eyelids are affected by seborrheic dermatitis.

Vision problems appear: the eyes become bloodshot, a person begins to be afraid of light, he may experience vascular ingrowth into the cornea (vascularization), burning sensation in the eyes, develop conjunctivitis, inflammation of the cornea of ​​the eye (keratitis) and even cataract.

The lack of a sufficient amount of vitamin B2 in the body leads to iron deficiency anemia, as well as pathologies of the nervous system, which manifests itself in muscle weakness, unbearable pain in the upper and lower limbs.

There are several reasons why a person has a lack of vitamin B2: its insufficient intake in the body with food (unbalanced nutrition), non-compliance with the rules for storing products containing this important component. This results in a decrease in its concentration in the blood.

Chronic diseases of the gastrointestinal tract, as well as a course of treatment with drugs that act as Riboflavin antagonists, lead to the same.

Pharmacokinetics

Riboflavin and its complex biological substances (nucleotides) are quickly absorbed from the stomach or intestines. If a person has pathologies in the work of the gastrointestinal tract, for example, he is sick with chronic gastritis, achilia or enteritis, then the absorption of Riboflavin is sharply reduced.

It is unevenly distributed in the human body: its highest concentration is observed in organs such as the liver, kidneys and myocardium.

Riboflavin is able to cross the placenta and be excreted in breast milk of a nursing woman.

In the duodenum, the drug is rapidly absorbed, and its final excretion from the body is in the kidneys in the form of metabolites. The half-life of it from the body is from 66 to 84 minutes. If it is used in high doses, then it is excreted from the body unchanged.

Application

Riboflavin tablets, the price of which differs in different pharmacies, is taken as a course. Usually it is a month and a half. The recommended dose is from 1 to 3 times a day (the dosage and the number of doses must be discussed with your doctor).

For children under 18

The drug is indicated for children of all ages. Children's dose ranges from 0.4 mg to 10 mg per day (depending on the age of the child) 1 to 3 times a day.

Infants up to six months are given Riboflavin at 0.4 mg per day, from six months to a year - 0.6 mg, from one to 4 years - 0.9 mg, from 4 to 8 years - 1.3. For children aged 9-13 years, the recommended daily allowance differs by gender: for boys it is 1.9 mg, and for girls - 1.7 mg.

For adults

Adults need to take tablets in an amount of 0.005 to 0.01 mg (daily dose) at one time. For more severe cases, the dose is increased to 0.01 mg 3 times a day.

If we compare the need for this vitamin in men and women, then it is slightly higher in the female sex. Therefore, women should take these tablets at a dose of 1.8 mg / day, and for men - 1.7 mg / day, although this indicator depends on lifestyle (for example, men involved in sports, or women during gestation should increase the daily dose).

For pregnant

In women, the risk of hypovitaminosis increases during pregnancy, so they are often prescribed vitamins. Riboflavin should be taken after consulting a doctor at the indicated dosage, which is usually 2.0 mg per day.

Nursing mothers should also make up for the lack of vitamins: they can take 2.2 mg of Riboflavin daily during the course.

If a woman during lactation pays great attention to proper and high-quality nutrition, consumes dishes rich in riboflavin (milk and dairy products, bread, cereals, meat, fish, green vegetables), then in such cases the need for additional no vitamins.

For the elderly

Elderly people, burdened with age-related diseases, need Riboflavin much more. Increased doses of this drug are also indicated for those who are engaged in hard physical labor or are seriously interested in sports.

Contraindications

If a person has hypersensitivity to the main component, Riboflavin treatment is contraindicated. Also, this prohibition applies to patients with renal failure (nephrolithiasis).

Overdose

With the usual regimen of Riboflavin treatment, an overdose is not possible. Since it has little solubility, this prevents it from being absorbed in dangerous amounts. Even if the dosage is increased, the kidneys are still actively removing some of the vitamin from the body.

You need to take a vitamin preparation, like any other medicine, according to the instructions and recommendations of the doctor. If you take the pills for a long enough time, the excretion from the body of not only this, but also other vital vitamins increases. And this may not have the best effect on human health.

When symptoms such as dry lips, brittle hair, frequent mood swings, stomatitis, lethargy, skin problems (dermatitis, frequent rashes, eczema), hair loss, low temperature, you need to pass tests and start treatment to fill the missing vitamins.

Side effects

The main side effect of the pill can be:

• an allergic reaction to any component of the drug;
• visual impairment;
• dysfunction of the kidneys.

Another feature of the drug: it can affect the color of urine, staining it in a deep yellow or unusually orange color, but this is harmless.

Drug interactions

Riboflavin tablets, the price of which may differ by an order of magnitude in different regions, does not interact in the same way with other drugs. Before starting treatment with Riboflavin, you should definitely familiarize yourself with which drugs it is better not to use it.

If you take Riboflavin simultaneously with anticholinergics, this leads to an increase in the absorption and bioavailability of the former. The reason for this result is a decrease in intestinal motility.

Thyroid hormonal drugs in combination with Riboflavin accelerate the metabolism of vitamin B2. The activity of some drugs is reduced if taken at the same time as Riboflavin.

These include antibacterial drugs such as:

• Doxycillin;
• Eryromycin;
• Oxytetracycline;
• Tetracycline;
• Lincomycin.

There is one strict prohibition: Riboflavin should not be taken with Streptomycin. These are incompatible drugs.

But the combination of Riboflavin with Chloramphenicol helps to reduce the side effects of the second drug, such as optic neuritis and problems with hematopoiesis.

Like any other medicine, Riboflavin cannot be used together with alcohol, since the absorption of the former into the blood in this case slows down. Vitamin B2 is poorly absorbed in the intestines when taken with Probenecid.

Storage conditions and periods

Riboflavin tablets, the price of which exceeds the price of the drug in the form of a solution, has a production date, which should not be exceeded, - 3 years.

It must be stored out of the reach of children and protected from direct sunlight. The temperature at the storage location should be kept within 25 ° C.

Conditions of dispensing from pharmacies

The drug is commercially available and dispensed without a prescription at any pharmacy or online pharmacy.

Analogs

Riboflavin has several analogs, for example, Riboflavin Mononucleotide. This is a solution for intramuscular administration. Sold in 1 ml ampoules in contour plastic packaging. Thanks to such an injection, all redox processes are regulated, metabolism is improved, and eye functions are improved.

The indications for use of this drug are the same as for Riboflavin. It can even be used by pregnant and lactating women according to indications. Features of its compatibility with other drugs are the same as for Riboflavin tablets.

Dosage:

children	injections of 2 - 5 ml
adults	5-10 mg (single dose) up to 3 times a day

The course of treatment is from a month to one and a half. The price of ampoules is from 97 to 113 rubles.

The next analogue is Vitamin B2. It is available in tablets, but has a more complex composition: it includes cellulose, lactose monohydrate, magnesium stearate, titanium dioxide and other components.

There are also differences in indications: Vitamin B2 is indicated for infections, hyperthyroidism, to improve the general condition after surgery and in chronic stress conditions.

Such tablets cannot be used if a person has an increased susceptibility to the components of the drug, pathology kidney disease (nephrolithiasis), as well as hypersensitivity to certain nonspecific irritants (idiosyncrasy).

Riboflavin tablets can be used for all categories of patients, including pregnant and lactating women (its price is 300 rubles). The age of the patients is not limited. The drug is indicated to be taken in order to prevent a lack of vitamin B2 in the body for people over 60 years old (1 tablet 3 times a day).

As a therapy, the dosage regimen is as follows: children under the age of 4 years - from 1 to 3 tablets per day (maximum daily dose). During the course, the dose ranges from 30 to 90 tablets. For adults, the norm is 2 - 3 tablets per day. The course of treatment for both adults and children is 1 - 1.5 months. The tablets can be crushed.

Riboflavin is also a generic drug, Riboflavin sodium phosphate. This drug has a wide range of applications.

It is recommended for the treatment not only of eyes, skin (eczema, neurodermatitis, dermatosis), but also for seborrhea, red acne, cirrhosis of the liver (in including alcoholic), viral hepatitis A, tropical sprue, inhibition of bone marrow hematopoiesis, Crohn's disease, and even with leukemia.

As a prophylaxis, this drug is used for burn disease, acute infectious diseases, frostbite, in phototherapy. Manufactured in China, Germany and India. The form of production is powder in a large container of 5 kg, tablets and solution for injection.

Dosage: adults take 5-10 mg tablets three times a day, and children take 2-5 mg once a day. The course of therapy is a month and a half.

Injections are given in a dosage of 1 ml (1% solution) once a day for 10 to 15 days, after which it is recommended to do injections 2 to 3 times a week. In total, you need to make 15 - 20 injections. For children, a sufficient course of 3 to 5 injections.

For eye treatment, the required dosage is from 0.2 ml to 0.5 ml daily for 10 to 15 days. In tablets, the price of the drug is 1950 rubles, and in solution - 96 rubles. 1 kg of powder costs from $ 100 to $ 150 (usually it is purchased by hospitals).

When choosing a generic drug for the treatment or prevention of vitamin B2 deficiency, one must take into account which country produces it and what is the reputation of the manufacturing organization.

Riboflavin (or Vitamin B2) is found in many foods. Adequate nutrition completely covers the lack of this vitamin in the human body. But if the body is depleted for any reason, it is necessary to take this drug in tablets or another form (as recommended by a doctor), choosing the most appropriate option for the price.

Riboflavin video

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