Caripazim for electrophoresis. Price, instructions for use, where to buy, reviews

Intervertebral hernia treatment at the initial stages, it is successfully carried out by the method of electrophoresis. The addition of medications such as Karipazim enhances the therapeutic effect. The affordable price of the drug allows it to be used for treatment in case of other problems of the musculoskeletal system.

Forms of release and composition of the drug Karipazim

In the composition of Karipazim there are enzyme and plant substances, it has good proteolytic (resorption) activity.

It is produced in the form of a lyophilisate, from which the solution is prepared, helps to reduce edema, relieves inflammation, stimulates the recovery process in tissues, and activates blood circulation processes. Electrophoresis performed with Karipazim provides a pronounced therapeutic effect.

Treatment with Karipazim is especially successful during the initial stage of the appearance of small hernias, the size of which does not exceed 6 mm. Therapy in this case will avoid surgical operations. Hernias larger than 7 mm are difficult to treat with this technique.

The active ingredient contained in the medicine is chemo-papain, in dosages of 700PE and 350PE.

In addition, the composition of the drug includes:

• proteolytic enzymes;
• peptidase A, B;
• carbohydrates;
• amino acids;
• potassium, calcium, magnesium and sodium salts.

The drug is obtained from the milky juice of papaya. It is a white powder with a yellowish tinge. The carton contains 1 or 10 bottles, each of which contains 10 ml of the substance. The drug is also available in the form of a gel.

Pharmacological properties

Caripazim for electrophoresis (the price corresponds to its effectiveness) contains papain, which restores the normal functioning of the vertebrae. Orthopedic surgeons and neurosurgeons actively prescribe electrophoresis in conjunction with the drug to patients who have intervertebral hernias.

Karipazim increases the rate of recovery, improves the clinical picture of the disease, while there is a positive trend after using the drug. The spine acquires elasticity, inflammation at the site of the hernia is reduced, and the effect on the root decreases.

The action of the drug:

• the hernia becomes more elastic;
• pinched nerves are released;
• cartilage softening;
• pain syndrome disappears;
• active tissue regeneration begins;
• the discs become stronger and more reliable.

In its natural form, papain is widely used in South Africa to treat purulent wounds as it has been shown to be superior to some antibiotics for its anti-inflammatory effect.

Papaya juice contains enzymes that allow the body to quickly repair connective tissue. Papain is similar in composition to pancreatic juice, a tryptic enzyme that is able to break down peptides and proteins. The active ingredient, papain, acts only on dead tissue.

Main pharmacological action: proteolytic agent, used externally to break down necrotic tissues, chemically close to trypsin and chymotrypsin.

Pharmacodynamics and pharmacokinetics

Karipazim for electrophoresis (its price is affordable for many patients), easily penetrating into tissues, forms a depot in the area of ​​the affected discs. So it acts on the connective tissue of the hernial protrusion and the disc itself. The active substance selectively affects the structure of the cartilage tissue protein, ensuring its increased secretion.

A proteolytic enzyme, papain, breaks down damaged cells when the disc nucleus degenerates. At the same time, the cartilaginous plates of small thickness are renewed.

Fibrous cartilage begins to replace the damaged disc. It takes more than a year to completely transform damaged discs into glassy cartilage, which explains the duration of the entire recovery process with the help of the drug.

Karipazim increases the secretion of collagen protein, due to which moderate scarring of the loose fibrous part of the disc occurs. At the same time, the biosynthesis of chondroitin sulfates is preserved, which increases the healing role of the nucleus pulposus of the intervertebral disc. Disc turgor is restored and becomes more elastic.

The action of the drug is based on the activity of cleaving enzymes:

• proteinases, which break down the bond between proteins and amino acids;
• papain, a plant enzyme;
• chymopapain, cysteine ​​proteinase.

The drug has no systemic effect on the body. Its introduction during electrophoresis promotes its selective accumulation in the affected intervertebral discs. All enzymes contained in Karipazim are completely biotransformed in the liver.

The active centers of all enzymes contain sulfhydryl groups. The drug has a decongestant and anti-inflammatory effect, improves blood flow. It also stimulates the cells of the immune system, enhances tissue regeneration and suppresses the activity of hyaluronidase, thereby reducing inflammation.

Indications for use

Karipazim is prescribed in orthopedics, traumatology, for various forms of spinal pathology.

The price of electrophoresis is not very high, it can be used as an independent procedure in the complex therapy of pathologies, such as:

• back pain;
• hernia and protrusion;
• osteoarthritis;
• sciatica;
• bursitis;
• myositis;
• articular contracture;
• arthritis;
• arthrosis;
• keloid scars of various origins.

The medication is used in neurosurgery for neurological diseases:

• to relieve pain in carpal tunnel syndrome;
• when treating neuritis of the facial nerve;
• in the treatment of spinal and cerebral meningitis.

Karipazim is used in surgery when cleaning purulent-necrotic foci.

Karipazim is used for:

• increasing the effectiveness of complex treatment of joints;
• improving the general health of the patient in the event of disc degeneration;
• removal of necrosis and treatment of burns;
• exclusion of surgical interventions;
• improving blood supply;
• obtaining an anti-inflammatory effect.

Contraindications

The drug is contraindicated in the following cases:

• exacerbation of diseases of internal organs;
• pregnancy, breastfeeding;
• individual intolerance to the components;
• hyperthermia;
• heart problems;
• acute infectious diseases;
• high blood pressure;
• high temperature;
• oncological diseases;
• skin diseases.

Certain forms of the disease - sequestered hernias, with foramenal nerve entrapment, impaired blood circulation in this area and severe pain that require surgical intervention - do not allow the use of medication means.

At what age can you use the drug for electrophoresis?

The drug is not recommended for children and adolescents under 18 years of age.

Instructions for use, dosage

Before starting treatment, the patient should undergo an MRI session to determine the exact location and size of the hernia. The drug is administered by electrophoresis.

Method of application for diseases of the spine:

1. Immediately before the procedure, Karipazim should be diluted with saline. This requires 10 ml of saline solution, in which 1 g of dry powder is diluted. To enhance the effect, add a few drops of Dimexide, which has good penetration and increases the tissue's susceptibility to active substances.
2. The prepared solution is applied to filtered white paper, on which the electrode pads will be placed on top. Then an electrophoresis session is performed. The ultrasound head of the device moves slowly in circular and longitudinal movements along the damaged areas. The drug is injected with direct current from the positive pole. The current strength is from 10 to 15 mA. Euphyllin is applied to the electrode with the minus pole, Karipazim is applied to the pad with the + sign. Ultrasound of 800–1000 kHz is applied to damaged segments.

After electrophoresis, it is recommended to rub in an anti-inflammatory cream to prolong the action of Karipazim.

The course of therapy includes 20 procedures, but after 2-3 sessions, you can notice a significant improvement in well-being:

• convulsions become less pronounced;
• the pain goes away;
• the hernia decreases in size.

After completing the course, the doctor assesses the patient's health. There should be a break of at least 30 days between treatment cycles. To ensure a good result of electrophoresis with Karipazim in the treatment of hernias of the lumbar or cervical spine, the procedures must be regular. This method is often complemented by other treatments.

To consolidate the positive effect, you can adhere to a diet developed individually. Often doctors add turpentine baths and gymnastics to the treatment course.

The therapy can be done at home. A special device for conducting electrophoresis will help with this. You also need flannel disposable wipes, the size of which is determined by your doctor. The conductive layer is inside the wipes. The solution of Karipazim should be applied to a napkin with a + sign. The set includes disposable filter paper pads.

You can master the technique of conducting a session using a special brochure "Medicinal electrophoresis".

Gel Karipazim is applied using ultrasonic waves. The procedure does not require any auxiliary components. The consumption of the ointment is 10 ml. The gel is preliminarily rubbed with light movements into the area of ​​damage, and then the phonophoresis procedure is started.

Side effects

Karipazim for electrophoresis (the price of the drug does not differ much from analogues), used in orthopedics, in some cases causes complications:

• inflammatory reactions in the form of urticaria, itching;
• after 5 and 8 procedures, pain may appear, exacerbation of the underlying disease, which gradually disappear;
• local allergic reactions that are neutralized by hydrocortisone or Tavegil.

There are also some disadvantages:

• frequent allergic reactions;
• non-observance of the correct parameters for the use of electrophoresis with a drug leads to a decrease in the effectiveness of the drug;
• the procedure is long, takes a lot of time;
• high cost of the general course of treatment;
• development of an inflammatory response is possible.

Overdose

Information about a possible overdose has not been reported, since the drug does not affect the internal organs of a person.

special instructions

The use of electrophoresis in the elderly is possible only under the supervision of a physician. For them, the working parameters are selected individually due to the possibility of complications from the cardiovascular system.

You can not use the solution intramuscularly and intravenously, the procedures are carried out only under the supervision of specialists.

To obtain the desired result, it is necessary to observe the regularity and systematicity of the procedures. For a quick recovery, it is necessary to take vitamin supplements between treatment cycles. After treatment, myostimulation of the paravertebral muscles, support of their tone with the help of daily gymnastics, has a positive effect.

Drug interactions

There are no clinical data on the incompatibility of Karipazim with other drugs. Before starting the procedures, you should consult with your doctor to find out all the details.

Alcoholic drinks do not affect the effect of papain.

Analogs

In pharmacies, you can find several drugs with a similar active substance:

• Karipain. A unique feature of its composition is the added chondroprotectors to improve the structure of the cartilage. The main components are papain, a protein enzyme, glucosamine, hyaluronic acid to reduce pain and prevent cartilage degradation. Available in two forms: ointment and freeze-dried powder. Karipaim is applied topically by injection using electrophoresis or phonophoresis. Actively affects the intervertebral hernia, the entire intervertebral disc.
• Papaya milky juice. The substance contained in the preparation refers to enzymes, breaks down necrolyzed tissues, liquefies blood clots, exudates. It is applied topically in the form of a solution, which is prepared on the basis of 0.9% NaCl. It has a positive effect on burns for the early rejection of scabs.
• Papain. The pure, natural enzyme papain comes in powder form. Used to prepare a solution, used for burns, as a blood anticoagulant in the treatment of thrombosis.

The drugs have a similar effect:

• Chymotrypsin. Enzymatic, proteolytic, anti-inflammatory substance of protein nature. Breaks down fibrinous formations, necrotic tissues. It is used for thrombophlebitis, otitis media, sinusitis, with hemorrhage in the anterior ocular chamber, burns, exudative pleurisy, purulent wounds. On sale it is presented in powder form. Before use, it should be dissolved in a saline solution consisting of 0.9% NaCl. The medicine is applied to the wound area in the form of applications.
• Trypsin. It is produced in crystalline, fermented form and as a solution. The active enzyme in its composition, trypsin, breaks down proteins, peptides, has anti-inflammatory properties, and liquefies viscous secretions. The solution is used with electrophoresis, phonophoresis, in the form of a skin powder. According to indications, it is used in the case of:

1. acute thrombophlebitis;
2. treatment of purulent burns and ulcers;
3. lung abscess;
4. chronic purulent otitis media, sinusitis, sinusitis.

• Himopsin. The drug is created on the basis of active enzyme substances - trypsin + chymotrypsin. Proteolytic drug for local consumption.It is produced in the form of a lyophilisate for the preparation of a solution that treats:

1. bronchopulmonary diseases;
2. thermal burns;
3. chronic rhinitis, otitis media, sinusitis;
4. purulent wounds.

Terms, conditions of sale and storage

Store in places protected from children, sunlight, at a temperature not exceeding + 15˚С. The shelf life is calculated from the date of production, but cannot exceed 18 months.

The medicine is sold by prescription, since it is advisable to discuss electrophoresis sessions with a medical doctor beforehand.

Price

Karipazim for electrophoresis (the average price for the regions differs little) can be purchased in many pharmacy chains. The cost depends on the manufacturer and the number of bottles in the package.

Drug name	The volume of the bottle	Price in rub.	Manufacturer
Freeze-dried caripazim for external use application	350 PE bottle, 10 ml	76–150 86–160	Vifitek HoneyFlorin
Karipazim lyophilisate	350 PE 10 pcs. 10 ml each	935–1472 1007	Vifitek Medflorin

The average price of Karipazim by region is from 100 to 250 rubles. for 2 bottles. The cost of 10 bottles is from 800 to 1100 rubles. In online pharmacies, the product can be purchased at a lower price.

The use of Karipazim in conjunction with electrophoresis significantly reduces pain in the spine, since the drug has good chondrolytic properties. The price of a medicinal product corresponds to its effectiveness.

Video about Karipazim

Can Karipazim treat a hernia: