Otofag gel for children. Reviews, instructions for use, where to buy, price

Otofag is a gel formulation intended for use in children and adults. Reviews about him speak of good efficiency, thanks to which in some cases it is possible completely suppress the infection without the use of antibacterial agents.

Indications for use

Bacteriophages are living microscopic creatures that can develop and multiply only in certain types of bacterial cells. Interest on the part of scientists in them has reappeared for the reason that most infections acquire a pronounced resistance to the action of antibiotics already at the development stage.

On average, the resistance of pathological agents to them in previous decades has developed over 20-30 years. Now the same figure does not exceed 2-3 years. The trend continues to gain momentum, so scientists are constantly looking for effective ways to kill pathogens.

Among the indications, the following purposes of use are stated:

• hygiene of the auricle during periods of spread of infections;
• destruction of pathogenic microflora in acute symptoms;
• parallel courses of radiation and chemotherapy;
• treatment of rhinitis of any origin;
• increased local immunity;
• changing of the living place.

Otofag is a gel for children, reviews of which mainly speak of high efficiency, can be used without the presence of obvious symptoms, and in as an additional agent against the background of the main treatment against the following microorganisms:

• Staphylococcus aureus;
• haemophilus influenzae;
• Pseudomonas aeruginosa;
• intestinal infection;
• Morgan bacterium;
• streptococci.

This is not a complete list, therefore, the drug can be used with a large number of other pathogenic infections.

Composition and form of release

The composition of the cosmetic product includes the following components:

• 32 phage particles in saline;
• extract of calendula;
• purified water;
• carbopol;
• nipazole.

Outwardly, the gel is absolutely transparent, has no color, the smell is subtle, neutral. If swallowed, it does not cause any health effects.

The product goes on sale in plastic bottles with a convenient pump dispenser. The gel is produced by the Russian company NVTs Agrovetzashchita S.-P. Sergiev Posad. The average cost of 1 package is about 1000 rubles.

Pharmacodynamics and pharmacokinetics

Bacteriophages are active against pathological flora. At the same time, they have no effect on microorganisms that are characteristic of the natural balance of healthy human microflora on various mucous membranes inside and outside the human body.

Otofag is a gel for children, reviews of which note its high efficiency, the mechanism of therapeutic action shows the following features:

• fibrils or spines, which are located on the surface of the phage, bind to the receptor processes on the bacterial body;
• before the start of the next stage, a tight coupling is made, a system for blocking its activity is carried out;
• when the process is completed in sufficient volume, the bacteriophage injects a nucleic acid;
• genetic material comes like a syringe thanks to special processes with aggressive enzymes on the bacteriophage;
• further, the development of protein elements of new bacteriophages inside the bacterium begins from the genetic basis;
• after infection, a change in intracellular metabolism is observed in accordance with the needs of the phage;
• the final stage of the action of phages is the destruction of the walls of the bacteria with special enzymes, lysines.

As a result, the bacterium ruptures and dies, and young phages find themselves outside the limits of its body.

Thus, the advantage of bacteriophages is that they not only have a bacteriostatic effect, but also act bactericidal, destroying bacteria. Additionally, there is a low probability of the formation of resistance to their influence due to the specific features of the vital activity of bacteriophages.

For maximum therapeutic effect, it may be recommended to identify the type of pathogen to determine its sensitivity to a specific set of bacteriophages. Those. directly to the selected drug.

The excretion of bacteriophages and dead particles of pathological microorganisms occurs naturally, including the lymphatic and other systems.

Application for children under 18 years of age

The use of gels with bacteriophages is allowed from the neonatal period. Such drugs are gaining popularity among specialists and are actively prescribed by pediatricians and otorhinolaryngologists in pediatric practice.

Application mode for various indications:

• for inflammatory diseases of the mucous membranes of the throat and nose - in the first 2 days, the gel is administered as a single dose by pressing up to 4 times a day, then 2-3 times a day, from the 5th day, it is possible to switch only to 2 uses per day;
• with an increase in the risk of exacerbation of chronic diseases of the upper respiratory tract - in the case of an increase it is likely that the drug should be used at least 2-3 times a day after a single press on bottle piston;
• when confirming the diagnosis of Staphylococcus aureus, the agent is recommended to be used 2 times a day at approximately the same time intervals, the duration of the course is at least 1 week;
• during surgical interventions, the dosage and frequency of use per day should be determined by the observing specialist both before and after the main procedure.

The gel can be applied either by squeezing directly onto the mucous membrane, or using a cotton swab as a spatula. After processing, it is necessary to maintain a period of time of about 40 minutes, during which one should not drink, eat or rinse off the active composition.

Contraindications

Contraindications include only the revealed sensitivity or intolerance of the components that make up the gel. In such cases, you should consult a supervising specialist to eliminate symptoms and prescribe an alternative method of therapy for the underlying disease.

Overdose

The likelihood of significantly exceeding the dose with even very frequent use is unlikely.

Side effects

In some cases, an undesirable effect can be manifested as a result of the release of internal toxic substances during the rupture of bacteria. To restore normal health, it is recommended to use active enterosorbents to bind toxins and eliminate them from the body naturally through the intestines.

Drug interactions

The drug is well tolerated and can be combined with any other drugs. With the simultaneous use of local gels and solutions, it is recommended to maintain a period of about 30 minutes between their injections, alternating throughout the day.

Storage conditions and periods

The drug must be kept in a place closed to children at an ambient temperature of 2 ° C to 8 ° C. During transportation, it is allowed to increase to a level of no more than 25 ° C. Immediately after delivery, the drug must be placed in a refrigerator. Shelf life - 2 years while maintaining the tightness of the bottle.

Conditions of dispensing from pharmacies

Otofag is a gel for children, reviews of which contain information on methods of acquisition, does not require a prescription from the attending physician.

Analogs

Currently, few preparations with bacteriophages are produced. Some of them are intended for narrow use after determining the type of pathogen. Others can be applied to a wider range of diseases.

Staphylococcal bacteriophage

The medicinal product is produced by JSC NPO Microgen in Russia, g. Permian. At the moment, the company is the only manufacturer of medicinal bacteriophages in the country, which are registered as a drug in the state register of medicinal products.

Staphylococcal bacteriophage is offered to buyers in 2 release forms:

• 1 bottle 100 ml, price about 800 rubles;
• 4 bottles of 20 ml, the price is about 700 rubles.

Outwardly, the solution is a clear liquid with a yellowish tinge. Its intensity is not standardized and can be different.

The composition includes directly sterile filtrate of phagolysates of bacteria of the genus Staphylococcus. To give stability, the solution also contains the preservative agent hydroxyquinoline sulfate in an amount of 0.0001 g in 1 ml - converted to pure substance.

According to its biological properties, the drug causes active death of staphylococci and can be used for the following indications:

• staphylococcal infection;
• thermal damage to the skin;
• purulent wounds with complications;
• purulent sore throats, bronchitis;
• carbuncles and boils;
• infected wounds;
• household injuries;
• osteomyelitis;
• pleurisy;
• mastitis;
• bursitis.

The supervising physician should determine the necessity and expediency of treatment with the agent. When combined with antibiotic therapy, the effectiveness can be significantly increased.

Methods of administration of the solution:

• orally;
• rectally;
• locally.

Before use, the bottle must be shaken vigorously to evenly mix the components. It is recommended to use the drug after appointment by a specialist, who must himself determine the optimal method. introduction, frequency of use during the day and additional parameters to achieve maximum efficiency.

Gel with bacteriophages from the Mirra brand

Otofag is a gel for children and adults, which conventionally refers to medical gels. Cosmetic product from "Miraa" is available in 50 ml bottles. The average cost of 1 package is about 550 rubles. Expiration date - 1 year from the date of production. According to people's reviews, the texture of the product is dense, gel-like, the composition is supplied by pressing the dispenser.

Compound:

• extracts of clover, sweet clover, alfalfa;
• essential oils of sage and lavender;
• concentrate of bacteriophages;
• purified water;
• carbomer;
• cato.

The product neutralizes the pathological flora on the skin, quickly heals various injuries and restores normal microflora. It is recommended to apply the gel 2-3 times a day, massaging until completely absorbed. Rinse off the composition after this is not required. The duration of the application is not limited.

Other bacteriophages LLC NVC Agrovetzashchita S.-P.

The manufacturer of Otofaga releases several additional products.

Name	Purpose	Volume and price
Phagodent	For the oral mucosa	50 ml, from 850 rubles.
Fagotin	From gynecological diseases	50 ml, from 900 rubles.
Fagoderm	For skin diseases	50 ml, from 850 rubles.

The cost of each bottle varies considerably depending on the place of sale and the method of distribution.

Phagodent

The drug is intended to stabilize the microflora in the oral cavity, the use of which prevents the development of inflammatory processes on the mucous membranes. It includes a complex of 77 bacteriophages, which in practice fight against almost all bacteria that often multiply in this part of the human body.

Benefits of using Phagodent gel:

• the drug effectively blocks the development of microorganisms within 2-3 hours after the first application;
• with subsequent applications, the complex helps to restore the individual microflora;
• in the postoperative periods, the gel reduces the risk of developing inflammatory processes;
• has no taste, smell, does not stain tooth enamel.

Mode of use of the tool:

• the gel must be applied with rubbing movements on the mucous membranes;
• distribution of the active composition directly by the language is allowed;
• after using the gel, do not eat or drink;
• the duration of such an exposure after processing is 40 minutes;
• mode of application - 2-3 times a day in the amount of 1 press;
• the duration of the course is from 1 to 2 weeks.

To enhance the therapeutic effect, it is recommended each time before application to carry out a standard hygienic cleaning of teeth and gums using a toothbrush and soft paste.

Also, for optimal results, do not fill closed lesions with a drug that do not have a direct outlet for the outflow of exudate. Otherwise, if this indication is neglected, there will be a risk of developing a more pronounced inflammatory process and tissue swelling.

Fagotin

Otofag is a gel for children, reviews of which often contain information about other drugs from this line, includes a special agent with bacteriophages for the intimate zone.

Fagotin contains the following components:

• phage particles in 0.9% sodium chloride solution;
• extract of calendula and carbopol.

The drug allows you to successfully eliminate conditions in which there are significant imbalances in the balance of healthy microflora.

A complex of 40 types of bacteriophages quickly interacts with microbes and bacteria, thereby ensuring the normalization of well-being. Against the background of therapeutic activity, the growth and development of its own, healthy microflora in the external genital area begins.

Indications for use:

• decreased immune defense in diabetes, oncology, fungal and viral infections;
• daily care to maintain a healthy state of health in the intimate area;
• protection of negative influences from external influences;
• prevention of STDs before and after sexual intercourse;
• prolapse of the internal genital organs;
• autoimmune and viral diseases.

On the recommendation of a specialist, it is possible to use the product for other indications that require high protection against the penetration and growth of bacteria.

Mode of use of the tool:

• for medicinal purposes, the drug should be applied to the genitals;
• it is forbidden to wash off the product for at least 40 minutes after application;
• for 1 dose, it is recommended to take 5-7 ml after 5-7 pressing the plunger;
• the frequency of application can be up to 7 times during 1 day;
• the duration of course use is not limited.

Depending on the symptomatology of the particular case, the observing physician may recommend a different regimen and frequency of gel application.

Fagoderm

A hygienic product for maintaining healthy microflora of the skin and soft tissues contains the following components - 64 types of bacteriophages to suppress the activity of a wide range of pathological agents. Packing volume - 50 ml with pump dispenser.

Additional components:

• deionized water;
• extract from marigolds;
• carbopol;
• cato.

The product should be stored at temperatures between 4 ° C and 25 ° C. The guaranteed shelf life is 2 years from the date of production. During this period, it is not allowed to heat the product or expose it to negative temperatures.

Indications for using the product:

• periods after laser resurfacing and mechanical cleaning;
• healing of the umbilical wound in newborns;
• burns, wounds, insect bites; injuries, cracks;
• skin care with increased sweat separation;
• atopic dermatitis, fungal infections;
• elimination of unpleasant odors.

In the postpartum period, the agent avoids bacterial infection of the sutures in the intimate area. It is recommended to apply the gel 2-3 times a day in the amount of 1-3 pressings on the pump. On the recommendation of a specialist, you can adjust the mode over a wide range.

Otofag is a gel for children with good pharmacological properties. In addition to him, the market offers other means that, according to people's feedback, are no less effective for solving narrower, specific tasks.

Video about the drug Otofag

Indications for use of the drug Otofag: