Omacor. Analogues of this drug, instructions for use, where to buy, price, reviews of cardiologists

Omacor is a drug used in the treatment of certain functional disorders of the blood. The medication has a high cost, therefore it is often replaced by similar means.

Forms of release and composition of the drug

This medicine is produced in Germany in the form of oral capsules. The active substance of the remedy is the amount omega-3 polyunsaturated fatty acidsobtained from ethyl ether compounds.

Additional composition:

• 4 mg alpha-tocopherol;
• 293 mg gelatin;
• 135 mg glycerol;
• a sufficient amount of filtered water.

All capsules are contained in a glass bottle packed in a cardboard box.

Pharmacological properties

This medication belongs to the category of lipid-lowering drugs.

Pharmacodynamics and pharmacokinetics

The drug is highly active against blood lipids. At the same time, it significantly lowers the concentration of very low density lipoproteins, which as a result leads to a decrease in triglyceride levels. The agent also has an effect on hemostasis and blood pressure.

The action of the tablets is aimed at reducing the synthesis of triglycerides involved in the enzymatic reactions of the liver. A decrease in triglyceride levels also occurs under the influence of oxidative processes, in which liver fatty acids are involved.

The drug leads to an increase in the content of low density lipoprotein cholesterol, while practically does not affect substances with a high density.

At the moment, there is no information and proven relationship between a drop in triglyceride concentration and the development of ischemic disorders.

As a result of studies, it was found that the use of the drug led to an increase in the time required for blood clotting.

According to clinical observations, taking the drug leads to a decrease in the risk of myocardial infarction and stroke by more than 15%.

The use of capsules in patients with chronic heart failure led to a decrease in the risk of death from various causes by 9%, from cardiovascular diseases - by 8%. At the same time, a decrease in the risk of ventricular arrhythmias by 28% was also noted.

After absorption of the components of the capsules, fatty acids enter the liver, where they interact with lipoproteins. Thanks to this, the formed bonds can play the role of eicosanoids. The main amount of fatty acids is used to maintain a normal energy balance.

According to animal tests, the active substance undergoes hydrolysis. This leads to the fact that these substances become part of the composition of phospholipids and essential components of blood plasma cholesterol.

Indications for use

Omacor (analogs of this drug may have an additional or incomplete list of indications) is used in the treatment of hypertriglyceridemia and conditions associated with the development of pathology.

Indications:

• hypertriglyceridemia (endogenous form of pathology) - in the absence of the effectiveness of a lipid-lowering diet;
• hypertriglyceridemia - as a combination therapy in conjunction with statins;
• preventive treatment of myocardial infarction - as part of complex treatment in conjunction with other medications.

The medication is used only after clarification and confirmation of the diagnosis.

Contraindications

The medicine has some restrictions on the admission associated with the action of active substances or other characteristics of the patient's body.

Contraindications:

• intolerance to the active or auxiliary substances of the drug;
• the period of bearing or feeding the child;
• exogenous hypertriglyceridemia;
• minor age.

With extreme caution, capsules can be used for the following conditions and disorders:

• intolerance to fish products;
• advanced age - more than 70 years;
• functional disorders of the liver;
• endogenous hypertriglyceridemia (secondary damage);
• the presence of diathesis (hemorrhagic form);
• joint therapy with oral forms of anticoagulants;
• patients with diseases affecting the formation of bleeding.

Before taking the capsules, it is imperative to undergo additional studies for the presence / absence of contraindications.

https://www.youtube.com/watch? v = EZ0pphG-R80

At what age can the drug be used?

Omacor (analogues of this drug may also have age restrictions) is not recommended for children and adolescence under 18 years of age, since the efficacy and safety of the drug in this period of time is not installed.

Instructions for use, dosage

The medicine is intended for oral administration. Take capsules with or without food.

With the development of hypertriglyceridemia, 2 tablets are prescribed 1 time per day. With a low therapeutic effect, the dosage can be up to 4 tablets per day.

During secondary prevention of heart attack, the recommended daily dosage is 1 capsule per day.

The need to adjust the dosage in patients with renal insufficiency should be determined by the attending specialist, since the data on taking the drug in the presence of pathology are limited.

Side effects

In some cases, the drug can lead to the development of various negative manifestations associated with the action of the active ingredients or the physiological characteristics of the patient.

Side effects:

• Immune disorders: high sensitivity.
• Disruptions in metabolic processes: high potassium content, gout.
• Disorders in the central nervous system: dizziness, taste disturbances, headaches.
• Vascular disorders: low blood pressure.
• Respiratory pathologies: the formation of nosebleeds.
• Malfunctions of the gastrointestinal tract: dyspeptic disorders, the opening of bleeding in the gastrointestinal tract.
• Hepatic dysfunctions: functional liver disorders (elevated transaminases).
• Skin manifestations and signs: rash, urticaria, itching.

In the event of adverse reactions, including symptoms not noted in the instructions, it is necessary to cancel the further use of the drug and consult a specialist.

Overdose

There is no information on drug overdose. However, if the indicated dosages are exceeded and negative reactions develop, it is necessary to consult a specialist for the appointment of symptomatic therapy.

special instructions

Omacor should only be used if there is no allergy to fish and fish products. When using the drug or its analogs, it is also necessary to preset the degree of sensitivity to fish components.

The drug is able to exhibit moderate activity in terms of blood clotting time. Therefore, constant monitoring of patients with blood clotting problems or undergoing treatment with anticoagulants, as well as other medications that affect hemostasis, is required.

It should be borne in mind that in patients with a high risk of bleeding, taking the drug can increase the blood clotting time. In this case, the drug can lead to a decrease in thromboxane A2. No other changes in blood clotting parameters were found. At the same time, the incidence of bleeding did not increase.

Taking capsules in some cases led to an increase in the activity of liver enzymes. At the same time, there are no reliable data on the effect of the drug on the development of pathologies in patients with functional disorders of the liver.

According to animal studies, the drug is not toxic during pregnancy. However, the effect of the drug on humans has not been established. It is recommended to use capsules while carrying a child only in case of justified risks.

The ability of the components of the drug to penetrate into breast milk has not been studied. Therefore, it is recommended to stop taking pills during the feeding period.

There are no data on the effect of the drug on human fertility.

There are no data on the effect of the drug on the ability to drive a car or carry out work requiring high psychomotor functions. However, it is assumed that the drug does not have or has an insignificant effect on the psychomotor functions of a person.

Drug interactions

According to studies, the simultaneous use of capsules and oral anticoagulants, as well as other drugs that affect hemostatic processes, led to an increase in clotting time blood. At the same time, there were no hemorrhagic complications.

When the main agent is combined with acetylsalicylic acid, it can increase the blood clotting time. Therefore, before starting therapy, it is necessary to inform the patient about this.

Simultaneous administration of the drug with warfarin did not cause any changes or complications from the hemorrhagic functions of the blood. However, it is recommended to undergo continuous blood tests when prescribing medication with other medications.

You must inform the attending specialist in advance about taking other drugs during the period of administration of the capsules. This will avoid the development of complications or other negative symptoms caused by a combination of drugs.

Analogs

Omacor (analogues of this drug may have a different cost from the original) in some cases can lead to the development of hypersensitivity reactions. If such symptoms occur, capsules should be replaced with other medicines similar in action and indications.

Analogs:

• Omegatrine. A domestic pharmaceutical company is engaged in the production and release of this drug.

  

  The tool belongs to the category of dietary supplements and is made in the form of oral capsules. The preparation contains various polyunsaturated fatty acids. The action of the dietary supplement is aimed at improving metabolism, increasing immunity, as well as lowering cholesterol and preventing the development of atherosclerosis. List of indications: risks of atherosclerosis, high blood cholesterol, ischemic heart disease, high blood pressure, prevention of blood clots, mental and physical overload. The recommended dosage is 2 capsules 2-3 times a day. Use the product with meals. The duration of treatment is 1-2 months. Repeated courses are possible only by appointment of the attending specialist and a break. Contraindications: intolerance to the components, the period of gestation or feeding of the child. Dispensing method - without a prescription. The cost of a dietary supplement in pharmacies in Moscow and the Moscow region ranges from 175 to 345 rubles.

• Vitrum Cardio omega-3. This product is manufactured by an American pharmaceutical company in the form of oral capsules. The preparation contains polyunsaturated fatty acids and tocopherol. The drug belongs to drugs of animal origin. The action of the capsules is aimed at restoring lipid metabolism and preventing the development of atherosclerosis. In this case, the drug exhibits a protective and antiarrhythmic effect. List of indications: prevention of disorders caused by malfunctions in lipid metabolism, lack of vitamin E in the body, complex treatment of lipid metabolism disorders. Take capsules after meals (after 30 minutes). Dosing regimen: for prophylaxis - 1 capsule 1 time per day, as the main therapy - 2-3 capsules per day. The duration of treatment should be at least 3 months. Reuse is possible after consulting a specialist. Contraindications: intolerance to the composition of the medication, chronic course of cholecystitis or pancreatitis, gallstone disease, hypatobiliary disorders, pathologies accompanied by hemorrhagic syndrome. Method of implementation without a prescription. The cost of capsules in state and commercial pharmacies in Russia ranges from 1,700 to 2,300 rubles.
• Doppelgerz Active omega-3. This drug is manufactured in Germany in the form of oral capsules. The product belongs to the group of dietary supplements. The capsules contain fish (salmon) oil and tocopherol (vitamin E). The drug is used as an additional source of polyunsaturated fatty acids. Indications: decreased immunity, increased cholesterol levels, cerebrovascular accidents, cardiovascular pathologies, atherosclerotic lesions, disruptions in lipid metabolism. 1 capsule is prescribed per day 1 time per day. Take the tablets with meals. The duration of the course can vary from 1 to 3 months. Re-use of dietary supplements is possible only on the recommendations of the attending specialist and a short break. It is forbidden to use capsules in the presence of intolerance or hypersensitivity to fish or other active substances. Vacation conditions - over-the-counter. The cost of a dietary supplement in Russian pharmacies ranges from 407 to 910 rubles.

Omacor (analogs of this drug may have additional indications or contraindications) should be replaced by other means only after agreement with the attending specialist. This takes into account the patient's condition and the degree of tolerance of the active composition.

It is not recommended to independently select and take analogs, since an incorrectly selected remedy can lead to a worsening of the condition or cause the development of complications.

Terms, conditions of sale and storage

• It is recommended to store the drug in a dark dry room at a temperature not exceeding 25 ⁰C.
• The shelf life of the product is 3 years from the date of manufacture.
• Do not use capsules after the expiry date stamped on the package.
• Terms of sale of the product - by prescription.

Price

The cost of the drug may vary depending on the region or area of ​​sale of the drug. You can find out the exact cost of a medicine at any pharmacy located in your place of residence.

Region / region	Form / dosage	Price
Moscow, Moscow region	Capsules, 1000 mg	RUB 1408-2765
St. Petersburg	Capsules, 1000 mg	RUB 1674-2700
Saint Petersburg (suburbs)	Capsules, 1000 mg	RUB 1698-2343
Leningrad region	Capsules, 1000 mg	RUB 1678-2229
Novgorod region	Capsules, 1000 mg	1944-2030 rub.

Before using Omakor, you should consult with a specialist and carefully study the annotation on the use of the drug. It is also recommended to read the reviews of patients who have taken the drug or its analogues.

Video about Omakor

Direct path to the heart - Omakor: