Genferon (Genferon) spray in the nose. Instructions for use for children, during pregnancy, where to buy, price, reviews

Genferon is a medicine, prescribed in the treatment of colds accompanied by nasal congestion. The spray is slightly overpriced, justified by the high efficacy of the drug.

Forms of release and composition of the drug

This medication is produced in Russia in the form of a nasal spray. The following substances act as active components: human recombinant interferon and taurine.

Additional composition:

• Trilon B;
• dextran 40 thousand;
• glycerol;
• sodium chloride;
• potassium chloride;
• sodium phosphate 2-substituted;
• potassium salt of phosphoric acid;
• peppermint oil;
• preservative E218 (para-hydroxybenzoic acid methyl ester);
• injection water.

The medicine is contained in a plastic bottle equipped with a dispenser. Each bottle is packed in a cardboard container.

Pharmacological properties

The drug belongs to the category of combined drugs with antiviral, immunomodulatory and antioxidant properties.

Pharmacodynamics and pharmacokinetics

Genferon is a spray in the nose, which has an antiviral effect due to an increase in the activity of enzymes that suppress the reproduction and activity of pathogenic microorganisms.

The immunomodulatory properties of the drug are due to an increase in the immune response aimed at the action of most pathogenic microflora and cells exposed to bacterial action.

The process takes place due to the following reactions:

• an increase in the active action of natural killers;
• increased activity of B-lymphocytes and increased antibody production;
• enhanced action of the monocytic-macrophage system;
• activation of cellular processes in which solid particles are digested;
• increasing the immune response at the molecular level, which allows the immune system to recognize the affected (infected) cells.

Thus, the drug exhibits a pronounced antibacterial effect.

Under the influence of the main component (interferon), there is an increased production of leukocytes located in the mucous cavity. In this case, these substances are directly involved in the suppression of pathological processes. Thanks to this effect, the production of immunoglobulin A (IgA) is improved.

The second active substance (taurine), when ingested, leads to the restoration of metabolic reactions and accelerated healing of damaged tissues. This component exhibits high antiviral and immunostimulating properties and represents an antioxidant that inhibits the development of various disorders associated with excess in the body oxygen.

The combined action of 2 components leads to a more pronounced therapeutic effect.

The drug has a low degree of absorption and bioavailability. This effect is due to the influence of protein compounds located in the nasal mucosa, which are responsible for the penetration and transport of various substances.

A small proportion of the drug is able to enter the systemic circulation. Thanks to this action, an increase in systemic immunity is noted.

Indications for use

The drug is prescribed for the prevention and treatment of colds, as well as acute respiratory viral infections.

Contraindications

The drug has some restrictions on use associated with the special condition of the patient or the influence of active ingredients.

Contraindications:

• intolerance to the composition of the product;
• children under 14 years of age.

The medication should be used with extreme caution in patients with nosebleeds.

At what age can the drug be used?

Genferon is a nasal spray that can be used in pediatric practice from the age of 14. In this case, treatment should be carried out under the supervision of a treating specialist.

Instructions for use, dosage

The tool is indicated for topical use in otolaryngology.

Application rules:

• Remove the protective cover.
• Perform several control clicks on the dispenser until a thin jet is formed.
• When using, the bottle with the product must be kept in an upright position.
• Instillation is performed alternately for each nasal cavity.
• After using the medication, the bottle should be closed with a protective cap.

It is not recommended to use the product at once for several family members, as such use can lead to infection of other persons.

For children

Children over 14 years of age at the first symptoms of the disease are prescribed 1 irrigation of the mucous membrane 3 times a day. In this case, the injection is carried out into each nasal cavity. The duration of therapy is no more than 5 days.

As a preventive measure, as well as in case of hypothermia, 1 injection is prescribed into each nasal cavity 2 times a day. The duration of treatment varies from 5 to 7 days.

For adults

For adult patients, the dosage is calculated based on clinical manifestations. Thus, at the first signs of a cold or ARVI, 1 irrigation of each nasal mucosa is prescribed 3 times a day. In this case, the maximum daily intake of the drug should not exceed 5 thousand. IU. The duration of the course is no more than 5 days.

Upon contact with an infected patient (cold or ARVI), as well as in case of hypothermia, the body is prescribed 1 injection into each nasal cavity 2 times a day. The duration of treatment is 5-7 days. After a break and a preliminary consultation with a doctor, it is possible to repeat the course.

During pregnancy and hepatitis B

According to clinical studies, the spray can be used during pregnancy, regardless of the trimester. No dosage adjustment is required.

The daily rate of the drug is as for an adult patient:

• With the development of ARVI, 1 irrigation is prescribed in each nasal cavity 3 times a day for no more than 5 days.
• As a prophylaxis, 1 injection is prescribed 2 times a day for 5 to 7 days.

Preventive treatment can be repeated after a short break and prior agreement with the attending specialist.

Side effects

Genferon in most cases is well tolerated by all groups of patients and is not addictive. With the correct use of the drug in the treatment of nasal pathologies, the spray does not have a negative effect.

At the moment, no cases of side effects have been reported. However, with the development of any negative signs associated with taking the drug, it is necessary to consult a specialist for advice.

Overdose

Cases of drug overdose have not been registered at the moment. Subject to dosages, the agent does not have a negative effect.

However, if the established daily allowance is significantly exceeded or if the drug is accidentally swallowed and the development of negative manifestations, it is necessary to contact the attending specialist for the appointment of a symptomatic therapy. If the spray is accidentally swallowed, it is necessary to use sorbing agents and consult a treating specialist.

special instructions

This dosage form (spray) can be used during the period of gestation or feeding of a child. The agent is well tolerated and does not adversely affect the formation and development of the fetus.

The drug is used with high caution in patients with high risks of nosebleeds.

The medication does not have a depressing effect on the psyche or visual functions of a person, therefore it is allowed to drive a car or carry out other work that requires high psychomotor reactions.

Drug interactions

The product does not interact with other medications. However, it is not recommended to jointly use several different drugs at once that have a local immunomodulatory and anti-inflammatory effect.

During the period of prescribing the spray, you should inform the treating specialist in advance about other possible medications that may be taken, which will reduce the risks of developing an accidental interaction.

Analogs

Genferon is a spray in the nose, which in rare cases can lead to the development of allergic reactions. When such effects are formed, the agent should be replaced with another medication similar in action and indications.

Analogs:

• Timogen. This drug is manufactured in the form of a nasal spray by a Russian drug manufacturer. The main substance is alpha-glutamyl-tryptophan. The medication belongs to the category of immunomodulatory agents and is used in the treatment of the following diseases: treatment and prevention of ARVI, influenza and bacterial infections of the upper respiratory tract; postoperative period (to strengthen and restore immunity); infectious pathologies accompanied by a decrease in immunity; a secondary form of immunodeficiency caused by prolonged use of antibiotics, chemotherapy or radiation therapy. Dosing scheme: 1 irrigation in each nasal cavity 2 times a day. In this case, the duration of treatment is no more than 1.5 weeks. For prophylaxis, the agent is applied within 3-5 days. In childhood, 1 injection is prescribed 1 time per day. Re-use of the drug is possible after a break of 1 month. Contraindications: children under 1 year of age; intolerance to active ingredients. The medicine can be prescribed during gestation and breastfeeding. Terms of sale - without a prescription. The cost of a bottle in pharmacies in Moscow and the Moscow region ranges from 190 to 540 rubles.
• Grippferon. This medication is manufactured in the form of a nasal spray by a domestic pharmaceutical company. Interferon alpha-2b acts as an active ingredient. The drug has pronounced anti-inflammatory, antiviral and immunomodulatory properties. The indication for the administration of the spray is the prevention and treatment of influenza and acute respiratory viral infections. Dosing regimen (for children): 1-2 drops of the agent in each nasal passage from 3 to 5 times a day. Adults are prescribed 3 irrigations of each nasal cavity 5-6 times a day. As a preventive measure, the agent is used no more than 2 times a day. Preventive treatment can be repeated after a break and agreement with the attending specialist. List of contraindications: intolerance to the components of the drug; severe course of allergic diseases. The spray can be used during the period of gestation and feeding of the child. The method of selling through pharmacies is without a prescription. The cost of the drug in commercial and state pharmacies in Russia ranges from 245 to 370 rubles.
• Aqua Maris. This product is produced in Croatia in the form of a nasal spray. The main component is the water of the Adriatic Sea, which contains various trace elements. The medication has a local anti-inflammatory effect, helps to cleanse and moisturize the nasal cavity from mucus. List of indications: various diseases of the nasal cavity, nasopharynx or paranasal sinuses; the presence of adenoids; rehabilitation after surgical operations on the nasal cavity; rhinitis (allergic and vasomotor form of pathology); infectious lesion of the mucous membranes of the nose; excessive dryness of the nasal mucosa. In childhood, the recommended dosage is 2 irrigations from 4 to 6 times a day. Adults are prescribed 2-3 injections from 4 to 8 times a day. The duration of treatment in both cases varies from 2 weeks to 1 month. Contraindications: children under 1 year of age; intolerance to the components of the drug. The drug can be used during gestation or breastfeeding. The way of implementation is without a prescription. The cost of a bottle in regional and regional pharmacies in Russia ranges from 110 to 280 rubles.
• Viferon. This medicine is produced in the form of a gel for external use by a domestic manufacturer. The active substance of the drug is interferon alpha-2b. It exhibits high antiviral, immunomodulatory and anti-prophylactic properties. List of indications: complex treatment of influenza and acute respiratory viral infections, including pathologies complicated by the development of bacterial infection; preventive treatment of influenza and ARVI; treatment and prevention of laryngotracheobronchitis (stenosing form of the disease); herpetic lesions of the skin and mucous membranes. The agent is applied to the nasal mucosa or tonsils from 3 to 5 times a day. The duration of therapy is 5 days. For prophylaxis, the drug should be applied no more than 2 times a day for 2-4 weeks. The medicine can be used during the period of gestation and feeding of the child. Contraindication to the appointment of the gel is intolerance to its composition. The method of sale is over-the-counter. The cost of packaging in regional and regional pharmacies in Russia ranges from 120 to 220 rubles.

Genferon is a spray in the nose, which, in the event of hypersensitivity reactions, should be replaced with another agent only in agreement with the attending specialist. When prescribing analogs, it is necessary to take into account the degree of tolerance of certain components.

It is not recommended to select analogs on your own, since the wrongly chosen remedy can cause the development of allergies or other negative reactions.

Terms, conditions of sale and storage

• The spray should be stored in a dry place at a temperature of 2 to 8⁰C.
• The shelf life of the drug is 24 months from the date of manufacture.
• It is forbidden to use the medicine after the expiration date indicated on the package.
• Dispensing method - by prescription.

Price

Product prices may vary depending on the region and area of ​​sale. You can find out the exact cost of a medicine at any pharmacy located in your place of residence.

Region / region	Dosage form / dosage	Price
Moscow, Moscow region	Spray, 100 doses	RUB 410-960
St. Petersburg	Drops, 10 ml	RUB 125-610
Saint Petersburg (suburbs)	Suppositories, 250,000 IU	RUB 175-1030
Novgorod region	Spray, 100 doses	RUB 555-770
Leningrad region	Spray, 100 doses	440-890 rub.

Before using Genferon, you should carefully read the instructions for using the spray and consult a specialist. Additionally, it is recommended that you familiarize yourself with patients who have taken the drug as a treatment for nasal diseases.

Video about the drug

Review of the doctor about the drug Genferon: