Zinnat (Zinnat) antibiotic suspension for children. Instructions for use, dosage, reviews, price

Zinnat is quite effective an antibiotic that is used to treat children and adults. The drug has pronounced properties, is active against various pathogens and is available in several dosage forms, which makes it easier to prescribe to children.

To get the maximum benefit from the product, you must take it as directed by your doctor.

Indications for use

The drug is a drug from the group of 2 generation cephalosporins, which helps to destroy most bacteria that provoke inflammatory diseases of the respiratory tract, organs of the urinary system and other pathologies. The drug has pronounced antibacterial properties.

The main indications for the use of an antibiotic in the treatment of children and adults:

• Diseases of the skin of an infectious origin. The remedy is prescribed for purulent infected wounds, boils, carbuncles and abscesses. In this case, the stage of development of the disease does not matter.
• Lyme disease in patients over 12 years of age. It should be noted that the medicine is used not only for treatment, but also for the prevention of complications.
• Infectious and inflammatory diseases of the upper and lower respiratory tract. The drug is effective in the defeat of the mucous membrane of the nose, throat and larynx, therefore it is prescribed for tonsillitis, pharyngitis, laryngitis. It is allowed to use the drug for adenoids localized on the nasal mucosa, for bronchitis and pneumonia.
• Pathology of the hearing organs, for example, otitis media.
• Sinusitis and sinusitis in acute, chronic form.
• Meningitis of varying severity. In this case, the drug is considered effective precisely at the initial stage, when there are no complications.

  

• Peritonitis, provoked by a rupture of the appendix or internal bleeding during perforation of the intestinal wall, stomach.
• Infectious pathologies of the urinary system. Pyelonephritis and cystitis respond well to treatment with a remedy. It can be used for urethritis as well as inflammation of the prostate gland in men.
• Pathologies of the organs of the reproductive system in women are also treated with the help of the remedy. It is prescribed for adnexitis, endometritis, in order to prevent complications after diagnostic curettage.
• Sexually transmitted diseases such as gonorrhea are also treated with antibiotics. Such disorders are not typical for children, but adults suffer from them quite often.

The drug can be used for long or short courses, depending on the severity of symptoms and the sensitivity of microorganisms to the active component of the drug.

Compound

Zinnat antibiotic for children contains as the main active ingredient the substance cefuroxime axetil, due to which the therapeutic effect is carried out. The ingredient has antibacterial, anti-inflammatory properties, and also prevents the spread of bacteria throughout the body.

The tablets contain auxiliary ingredients:

• Microcrystalline cellulose.
• Sodium lauryl sulfate.
• Colloidal silicon dioxide.
• Hydrogenated vegetable oil.
• Croscarmellose sodium.

The granules also contain auxiliary ingredients in the form of sucrose, aspartame and stearic acid. Additionally, the granules contain povidone and flavor. Excipients in any form of drug release do not have therapeutic properties, but are an important part of the drug.

In what form is it produced

There are 2 forms of drug release - tablets and granules for the preparation of oral suspension. The tablets are white, small in size and biconvex oval in shape. They are packaged in blisters of 10 pieces. An individual cardboard box contains 1 plate and an instruction explaining the rules for using the medication.

The tablets do not have an unpleasant odor, but they have a specific bitter taste. It is worth noting that 1 tablet may contain 125 or 250 mg of the active ingredient.

Granules are used to prepare a suspension for oral administration. As a rule, this form of release is intended for young children who cannot yet swallow a pill. The granules are small, white, and irregular in shape. They are placed in a glass vial, where water is added to obtain a suspension.

A measuring spoon is attached to each bottle, it is placed in a cardboard box, where you can also find instructions for using the medication. The bottle always has a corresponding mark indicating the boundaries of filling with water.

The cost of the tablets is 250-390 rubles. depending on the dosage of the active ingredient. Granules for obtaining a suspension cost approximately 280-320 rubles. The cost of the product may fluctuate depending on the region of distribution and the specific pharmacy.

Pharmacodynamics

Zinnat antibiotic for children has pronounced antibacterial properties. Since the active substance of the drug belongs to the group of 2nd generation cephalosporins, the drug has a bactericidal effect, that is disrupts metabolic processes inside pathogens, which leads to their rapid death as a result of the lack of sufficient nutrition.

The tool has a wide range of antimicrobial activity and effectively destroys gram-positive and gram-negative bacteria. Antimicrobial action is noted in the fight against aerobic and anaerobic microorganisms, which makes the drug effective in various diseases.

When it enters the systemic circulation, the active substance is concentrated in the area of ​​accumulation of microbes that provoke inflammation. This allows you to immediately provide an effect on bacteria and prevent complications when they spread.

Cefuroxime leads to disruption of metabolic processes in the membranes of microorganisms. As a result, there is an almost complete cessation of their vital activity, followed by death.

Due to the destruction of microbes, there is a gradual elimination of tissue edema, cell restoration and normalization of the patient's condition. Additionally, the local temperature decreases if soft tissues are affected. If the pathology affects the internal organs and systems, then when taking the medicine, the body temperature gradually decreases and a significant improvement in the condition occurs.

The active substance of the drug helps not only to destroy microbes, stimulates tissue repair, but also helps prevent the progression of the disease, the development of complications. As a result, recovery occurs, the speed of which depends on the patient's body and the degree of neglect of the disease.

Pharmacokinetics

The pharmacological agent is slowly absorbed in the digestive tract, namely in the small intestine. The main substance enters the bloodstream, as well as into breast milk and crosses the placental barrier. Thereafter, cefuroxime spreads through the systemic circulation and concentrates in the area of ​​inflammation.

It is noted that the active substance is better absorbed into the blood when the drug is taken immediately after a meal. Food intake does not affect the effectiveness of the drug. The maximum concentration of the substance in the blood is detected 2 hours after oral administration.

Despite the good absorption of the drug, its bioavailability does not exceed 40%, which does not impair its effectiveness, but somewhat complicates processing.

Cefuroxime is almost not metabolized in the liver and is excreted unchanged from the body. It should be noted that during the hemodialysis procedure, the plasma concentration of the active substance decreases slightly, which weakens the therapeutic effect.

Most of the substance is excreted by the kidneys. In patients with pathologies of the urinary system, a slowdown in the period of elimination of ingredients from the body is observed. On average, the evacuation of cefuroxime takes up to 6-8 hours, depending on the dosage taken, the duration of the course and the patient's body. The ingredient does not accumulate in blood and tissues. Which also makes it easier to remove.

Application for children under 18 years of age

Zinnat is used to treat children of different ages, but the scheme may differ. An antibiotic in tablets and granules is prescribed by a pediatrician taking into account many characteristics. For each age group, there are rules for use and recommended dosages.

Patient age	Dosage and dosage regimen
Patients from 3 months to 2 years	For such patients, the remedy is prescribed taking into account the weight. There are 10 mg of active substance per 1 kg. Children under 2 years of age are prescribed a medicine in the form of a suspension for oral administration. 5 ml of the finished suspension contains 125 mg of the active ingredient, that is, 25 mg in 1 ml. It is from this calculation that the dose for the child should be determined. A single dose should be taken 2 times a day for 5-7 days. With a severe course of diseases and the appearance of complications, the dosage is increased to 15 mg per 1 kg of body weight. The daily allowance for this age group should not exceed 500 mg of the active substance.
Children from 2 to 3 years old	Patients over 2 years old are prescribed 125 mg of the drug 2 times a day, that is, it is necessary to take a suspension of 5 ml in the morning and in the evening. The duration of the course is 5-10 days, depending on the severity of the symptoms. Such patients are not prescribed tablets, only a suspension after preliminary preparation.
Patients from 3 to 12 years old	Patients from 3 years old receive tablets 2 times a day. As a rule, a single dose is 125 mg, that is, 1 tablet. If necessary, the dose is increased to 500 mg, in which case it is required to purchase tablets with a dosage of 250 mg and take 1 piece 2 times a day. The maximum duration of a therapeutic course is 10 days. If there is no effect from the use, another medication is selected
Children from 12 to 18 years old	Patients over 12 years of age are prescribed 1250 mg of the drug 2 times a day, that is, taking 1 tablet in the morning and evening. It is worth noting that in the absence of an effect, the dosage is not increased, since the maximum daily intake is 500 mg. The duration of the use of the tablets is 10 days.

For adults, the drug is prescribed at a dosage of 250 mg 2 times a day for 7-10 days. If necessary, use another medication.

The preparation of the suspension should be carried out on the day of the start of the therapeutic course. To do this, a sufficient amount of purified water at room temperature is poured into a bottle with granules and shaken until completely dissolved.

There is a mark on the outside of the bottle, which is the border. It is up to this mark that the container should be filled with water. The ready-made mixture is used no longer than 10 days, after which its residues are disposed of. It is forbidden to take the medication after prolonged storage.

Contraindications

I do not use the drug for the treatment of patients suffering from individual intolerance to the components of the composition, as well as a tendency to similar manifestations. If in the past the patient has been allergic to cephalosporins, the drug is used with extreme caution, since there is a risk of a repeated negative reaction.

Contraindications include a severe form of renal and hepatic failure in the acute stage, when there is a significant violation of the functioning of organs. Do not prescribe medication during lactation and during the period of gestation due to its ability to penetrate into breast milk and through the placental barrier.

The tablet form of the drug is not used in the therapy of patients under 3 years of age, the suspension is not prescribed for children under 3 months. It is categorically contraindicated to use Zinnat when detecting an acute stage of disorders of the digestive tract.

Acute gastritis, pancreatitis, colitis is considered a reason for refusing therapy. Do not use antibiotics when diagnosing peptic ulcer in the acute stage. However, if inflammation in the abdominal cavity associated with a rupture of an organ is detected, the agent is not contraindicated.

With caution, the medication is prescribed for adults and children with chronic heart disease.

Overdose

Zinnat, an antibiotic for children, in case of violation of the rules of use, the development of severe dizziness and headache, the appearance of nausea and vomiting, not associated with food intake, is noted.

In addition, digestive upset is possible, manifested in the form of frequent loose stools. Such disorders lead to the development of dehydration, in which there is a clouding of consciousness in young children.

In case of an overdose, persistent insomnia or excessive drowsiness, the appearance of pain in the joints and muscles are possible. Some patients suffer from severe allergic reactions, which are accompanied by acute urticaria or Quincke's edema. Such complications can be fatal.

The most dangerous manifestation of an overdose is a seizure, in which various injuries and other complications are possible. If such signs appear, you should immediately stop taking the medication and visit a doctor. In a hospital setting, the stomach is washed out to the patient and symptomatic treatment is prescribed to normalize the condition.

Side effects

Complications when taking the drug occur in adults and children of any age. They can appear if the instructions are violated, but side reactions cannot be ruled out if all the rules are followed.

The most common reactions are:

• Headache and dizziness, accompanied by a deterioration in general well-being and a decrease in performance.
• Weakness and fatigue, aggravated by pain in the joints and muscles.
• Superinfection, in which the mucous membranes of the genitals, the oral cavity are affected by fungi. When the intestines are involved in the process, diarrhea is noted, which is quite difficult to treat.
• From the side of the hematopoietic system, it is possible to develop leukopenia, a decrease in the number of platelets and the appearance of signs of hemolytic anemia. Such disorders occur quite rarely, more often in children.
• On the part of the digestive tract, there is pain in the stomach and intestines, indigestion and lack of appetite. The condition is accompanied by intense thirst and dryness of the mucous membranes of the oral cavity.
• Some patients develop jaundice and mild hepatitis.
• On the part of the skin, it is possible to develop banal urticaria, but some patients show signs of Stevens-Johnson syndrome.

This disorder is one of the varieties of exudative erythema malignant form.

In this case, the patient develops a small rash not only on the skin, but also on the mucous membranes, which causes serious discomfort, makes it difficult to eat and drink. The disease is accompanied by itching and gradual opening of lesions with the release of a small amount of fluid.

If untreated, the condition progresses, lesions form on the skin, the appearance of which is associated with damage to the rash. A wet surface increases the risk of infection.

If such symptoms occur, it is worth stopping the use of the medication. Usually this is enough for the gradual disappearance of manifestations. If the signs do not disappear, symptomatic treatment is prescribed.

Drug interactions

Zinnat antibiotic for children should not be taken simultaneously with other drugs from the cephalosporin group, which increases the risk of complications. Do not combine the drug with aminoglycosides and loop diuretics, which increase the excretion of substances from the body and reduce the effectiveness.

You should not use the medication at the same time as antacids, which significantly reduce the concentration of the active component in the blood and weaken the effectiveness.

It is recommended to take the drug in combination with lactobacilli, for example, Linex. This will reduce the negative effects on the digestive tract, namely the intestines, which will help to avoid diarrhea.

There is no negative effect on the body when the antibiotic is combined with non-steroidal anti-inflammatory, vascular and antitussive agents. In each case, the doctor decides on the combination of one or another medication.

Storage conditions and periods

Store the medicine in a dark, cool and dry place. The maximum shelf life is 3 years for tablets and 2 years for granules.

The date of manufacture of the medicine is indicated on the package. Reception after the expiration date is prohibited.

Conditions of dispensing from pharmacies

You can buy medication in pharmacies with a doctor's prescription, which increases the risk of complications when using the medication on your own.

Analogs

The drug has several substitutes, which are used if the original cannot be used.

The most popular and effective counterparts:

• Cefutil - tableted medication based on cefuroxime. It is an absolute analogue of Zinnat and is prescribed to patients from 3 years old to relieve infectious and inflammatory pathologies of the digestive tract, hearing aid or respiratory organs systems. The daily dosage for a child is 250 mg, it can be increased to 500 mg if symptoms worsen. Adults are prescribed from 500 to 1000 mg per day. The course of treatment lasts from 5 to 10 days.
• Cefix - another analogue of the drug, which has similar properties, but contains cefixime in its composition. A medication is produced in the form of capsules and powder for the preparation of oral suspension. Children from 6 months to 12 years old are prescribed a suspension at a dosage of 4 mg per 1 kg of body weight 2 times a day. Patients over 12 years old are shown capsules, 2 pieces per day. The duration of use is 33-6 days.

Any of the analogues should be used only as directed by a doctor, especially when treating preschool children.

Zinnat is one of the most popular and effective drugs for children, which is highly effective in the treatment of infectious diseases. The antibiotic helps to cope with the symptoms of the disease and prevent its progression, the development of complications.

Video about the drug Zinnat

Zinnat is an antibiotic for children: