Flemoklav Solutab (Flemoclav Solutab) 1000 mg. Price, instructions for use, cheaper analogs, reviews

Flemoklav Solutab preparation is a fairly effective antibiotic that is used to treat patients of different ages and with various inflammatory disorders.

As a rule, the dosage of 1000 mg is used for adults, but there are other doses of the medication. The price of the drug is average, but its high efficiency fully justifies it. The use is recommended only for strict indications and after visiting a doctor.

Composition, release form, price

The drug carries out a therapeutic effect due to the content of 2 active components with high efficiency. The main effect is achieved due to the presence of amoxicillin, the amount of which is 875 mg. However, the properties of the component are enhanced by the presence of 125 mg of clavulanic acid.

The combination of these substances makes the product effective. There are auxiliary ingredients in the medicine in the form of povidone, sucrose, cellulose. The composition contains flavors, magnesium stearate and vanillin. The drug is available for purchase in pharmacies in the form of dispersible tablets used for the preparation of oral solution.

They are small in size, white in color and have an oblong biconvex shape. The tablets are packaged in blisters of 7 pieces. An individual cardboard box can contain 2 plates with tablets, as well as instructions explaining the rules for using the medicine.

The suspension obtained by dissolving the tablet has a sweetish taste, as well as the aroma of lemon or tangerine. The cost of a medicine in different pharmacies and regions differs. The average cost of funds is 500-600 rubles. When purchasing tablets with a lower dosage of the active ingredient, the cost will be lower.

Mechanism of action

Flemoklav Solutab 1000 mg (the price depends on the dosage of the active ingredient in 1 tablet) has pronounced antibacterial properties due to the content of amoxicillin and clavulanic acid. The mechanism of action of the drug is based on the ability of active substances to suppress growth and reproduction. pathogenic microorganisms that provoke inflammation:

• The tool has a wide range of antimicrobial activity, therefore it effectively and rather quickly destroys gram-positive and gram-negative bacteria. In addition, the drug equally effectively destroys anaerobic and aerobic microorganisms, as well as leptospira and tryponemes.
• Despite this, some strains of microorganisms are capable of developing resistance to the active components of the drug.
• The drug destroys bacteria not immediately, but by suppressing the synthesis of nutrient components in them. As a result, there is a violation of metabolic processes in the cell and the gradual death of bacteria.
• Mycoplasmas and chlamydiae are resistant to antibiotic action, therefore, when determining a disease provoked by such bacteria, the agent is not used.
• Additionally, the medication has an anti-inflammatory and antipyretic effect, which is explained by the suppression of the activity of microorganisms that provoke fever and the inflammatory process.
• Thanks to the complex effect on the body, the patient's condition improves, the most frequent complications are prevented, as well as the spread of bacteria through the systemic circulation.

After the active ingredient penetrates into the digestive tract, it is absorbed into the systemic circulation. The active substance is concentrated in blood, tissues and some fluids, which allows for maximum therapeutic effect. It is noted that amoxicillin and clavulanic acid do not accumulate in the body in large quantities, which reduces the risk of overdose.

The maximum concentration of components in the blood is detected 90 minutes after taking the drug. Active substances bind well to blood proteins, which explains the high bioavailability, reaching 90%. Moreover, the availability of amoxicillin always exceeds that of clavulanic acid.

The agent is well processed in the patient's body, namely in the liver. In patients with pathologies of this organ, a slowdown in the metabolism of substances is noted, which somewhat slows down the onset of the therapeutic effect, but does not weaken it. In diseases of the stomach, a slowdown in the metabolism of active components is also noted.

The evacuation of substances from the body is carried out for 4-8 hours, depending on the individual characteristics of the organism. The main amount of metabolites is excreted by the kidneys, a small part is evacuated with feces.

Despite the fact that the drug does not accumulate in the body in large quantities, its therapeutic concentrations can be detected in the gallbladder, pus, and muscle tissue. In addition, experts note the concentration of active ingredients in the synovial fluid and abdominal cavity. Due to this, the therapeutic effect is realized, as well as the scope of application of the drug is expanded.

Eating does not weaken the therapeutic effect of the drug, but somewhat slows down the onset of the effect. In elderly patients, this process slows down even when taken separately from food.

Indications for use

Flemoklav Solutab is prescribed to patients with various disorders. A dosage of 1000 mg of active ingredients is considered the best for adults, but the price of such a drug is quite high.

The main indications for the use of dispersible tablets are:

• Infectious pathologies of the upper respiratory tract, accompanied by an inflammatory process. The remedy is effective for tonsillitis, laryngitis and sore throat. It is prescribed for sinusitis, acute or chronic sinusitis.
• Inflammatory and infectious pathologies of the lower respiratory tract. Pneumonia of various forms and severity, acute and chronic bronchitis is considered an indication for prescribing a medication. In this case, the remedy is prescribed even if the symptoms of the disease worsen.
• Hearing system abnormalities, such as otitis media.
• Diseases of the reproductive system in women. With adnexitis and endometritis, the agent is prescribed when the first signs appear. In addition, you can use antibiotics for colpitis of infectious origin.
• Infectious and inflammatory pathologies of bone and cartilage tissue. The remedy is effective for osteomyelitis, arthritis of various origins, as well as inflammation of the cartilage tissue in the acute stage of arthrosis. In rheumatoid arthritis, the drug is considered very effective, since its main component is a derivative of penicillin.
• Purulent infected wounds, in which there is a slowdown in regeneration due to the multiplication of microorganisms on the affected surfaces.
• Infectious and inflammatory pathologies of the urinary system. The drug is effective for cystitis, urethritis, pyelonephritis of varying severity.

In addition, the remedy can be used not only in the acute course of diseases, but also in their transition to a chronic form with regular exacerbations.

Contraindications and side effects

The drug is not recommended to be taken in case of allergy to its components or a tendency to similar manifestations. With extreme caution, it is prescribed for intolerance to penicillins in the patient's history.

There are other contraindications:

• Internal bleeding of various origins.
• Acute period with gastric ulcer and duodenal ulcer.
• The terminal stage of renal or hepatic failure, in which the functions of the organs are severely impaired.
• Lymphocytic leukemia and infectious mononucleosis of any form and stage.
• Intolerance to cephalosporins.
• The patient's age is up to 12 years.
• Body weight less than 40 kg
• Acute period with a history of pancreatitis, as well as cholelithiasis, hepatitis or cirrhosis of the liver.

With extreme caution, the drug is used in the therapy of elderly patients suffering from vascular and cardiac pathologies. If the instructions are violated, they have an increased risk of complications.

Flemoklav Solutab 1000 mg (the price of the drug is quite high) often provokes negative reactions if the patient does not follow the rules for using the drug. However, if all recommendations are followed, the risk of complications is not excluded, but it is significantly reduced. As a rule, adverse reactions affect internal organs and systems.

Organs and systems	The most common complications
Nervous system	Headache is considered a common adverse reaction with medication. Patients may experience dizziness, weakness, and drowsiness. His performance decreases, signs of depression or apathy appear. Only a few patients have increased activity, restlessness and anxiety.
Digestive organs	Nausea and stomach pain occur frequently during treatment, especially when the patient refuses to eat. Irritation of the mucous membranes can lead to bowel pain, flatulence, loose stools, or persistent constipation. The second symptom is very rare, since the drug in most cases provokes diarrhea. In addition, patients have a deterioration or complete lack of appetite, intense thirst and dryness of the mucous membranes.
Vessels, heart and hematopoietic system	When examining blood during the period of therapy, signs of thrombocytosis or anemia, as well as leukopenia, can be detected. In some patients, there is a slowdown in blood clotting. Many patients report tachycardia, fluctuations in blood pressure indicators.
Genitourinary system	Itching in the vagina, the appearance of a specific discharge, or the development of thrush is considered a common complication of antibiotic treatment. Only in some cases does the drug lead to the development of nephritis, but only in patients who have previously suffered from any kind of kidney disease.
Skin	Allergic reactions to drugs of the penicillin group are common. Patients are worried about itching and burning of the skin, rash, irritation and peeling. If untreated, allergic rhinitis and conjunctivitis develop.

The degree of neglect of adverse reactions depends on the characteristics of the organism of a particular patient.

Instructions for use

The medication should be taken only as directed by a doctor and after a diagnostic examination. Reception of the prepared solution is carried out regardless of food, that is, it should be consumed 1 hour before or 2 hours after a meal. This will provide the maximum therapeutic effect.

The daily dosage for an adult is 2000 mg of the drug. This means that you should take 1 tablet 2 times a day, first dissolving it in 150 ml of purified water. The solution should be prepared immediately before taking, so as not to weaken its therapeutic effect. Children from 12 years old, if their body weight reaches or exceeds 40 kg, are prescribed the same dose of the drug as an adult.

The duration of the use of the medication depends on the specific disease. The standard regimen assumes taking pills within 1 week. After that, it is better for the patient to visit a doctor who will determine the advisability of further taking the drug.

If necessary, another 7 days of therapy are prescribed or another medication is selected. It is not worthwhile to independently increase the dose of the medicine or prolong the therapeutic course.

special instructions

Flemoklav Solutab 1000 mg (the price of the drug in a lower dosage is quite affordable) is prescribed after clinical examination of the patient's blood, as well as identifying the exact cause of inflammation and staging specific diagnosis.

The duration of use of the product for any disease does not exceed 14 days. In case of ineffectiveness of the medication, another medication is prescribed, since with prolonged use of Flemoklav, the risk of developing complications from the liver and kidneys increases.

Before starting treatment, the doctor asks the patient to eliminate the risk of developing an acute allergic reaction to the drug. It is also important to prevent complications if in the past he suffered from allergies to other penicillins or cephalosporins.

In patients with mild liver diseases, jaundice may develop during the period of treatment with Flemoklav, which is not considered a reason for canceling the drug if there are no other complications.

Application during pregnancy and lactation

The pharmacological agent is not contraindicated during pregnancy and lactation. However, its appointment should be made by a doctor according to strict indications.

Treatment is carried out under the supervision of a specialist, and the dosage is usually the same as that used for adults. The active components of the drug penetrate the placental barrier and pass into breast milk, but this is also not considered a contraindication for use.

Despite this, the remedy is prescribed only when the potential benefit to the mother outweighs the possible risk to the child.

Childhood use

Children from 12 years of age will be prescribed Flemoklav Solutab with a dosage of 1000 mg. However, for patients under 12 years of age, as well as those weighing up to 40 kg, lower doses of the agent are shown. As a rule, children under 5 years of age are prescribed tablets with a dosage of 125 mg.

Patients over 5 years old are shown taking the drug in a dose of 250 mg. Children from 8 years old are prescribed a remedy of 500 mg. For ease of use, the drug is available in different dosages. The dose is recommended for patients of any age 2 times a day after the preliminary dissolution of the tablet in water.

Pediatricians strongly advise against giving pills to a patient without a preliminary examination. In each case, the duration of the course is determined individually, but the maximum duration does not exceed 14 days.

Overdose

Flemoklav Solutab 1000 mg (the price of the medicine may differ in different regions) often provokes an overdose if the patient violates the instructions for use.

The condition is accompanied by nausea and bouts of vomiting, severe headache. Sometimes the patient develops a fainting state, there is pain in the joints and muscles, and weakness is observed. In rare cases, the patient falls into a coma, but for a short period of time.

Overdose is always accompanied by diarrhea, symptoms of dehydration, and lack of appetite. With an allergy to the drug, the patient develops acute urticaria, the skin becomes covered with large red spots, and unbearable itching is observed.

Symptoms are aggravated in the absence of therapy. There is no specific antidote to the drug, therefore, symptomatic therapy is used, gastric lavage is performed, and funds are prescribed to eliminate acute signs of an overdose.

Efficiency

The drug is highly effective in the treatment of pathologies caused by microorganisms sensitive to active ingredients. With the timely start of therapy, there is an improvement in the condition after 4 days of admission.

An unexpressed effect of the drug can be observed with an advanced course of the disease and the appearance of complications. But in all other cases, the remedy has worked well.

Drug interactions

The drug should not be combined with drugs that contain similar active ingredients. Simultaneous administration with other antibiotics is also prohibited. It is especially dangerous to combine Flemoklav with tetracyclines, cytostatics.

It is not recommended to prescribe the drug simultaneously with drugs based on acetylsalicylic acid, as well as with non-steroidal anti-inflammatory drugs. The use of an antibiotic with cardiac glycosides increases the concentration of the latter in the blood, which can lead to an overdose.

You can not combine the medicine with indirect anticoagulants, as the risk of bleeding increases. In each case, the doctor decides on the combination of one or another medication.

Storage conditions and periods

The drug can be purchased at the pharmacy with a doctor's prescription. Store it in a cool and dark place. It is important to keep away from children, moisture and direct sunlight. The maximum shelf life is indicated on the packaging, it is 2 years. The date of manufacture is also indicated on the packaging.

List of structural analogs cheaper than Flemoklav

The cost of the drug is quite high, so many are looking for a replacement for it among cheaper drugs.

The most popular structural analogs:

• Amoxiclav - a drug based on amoxicillin and clavulanic acid, produced in the form of tablets and powder for the preparation of a suspension for oral administration. The drug is effective, it is prescribed for adults and children, the tablets contain the same amount of the active ingredient. The price of the tool is 120-180 rubles.
• Augmentin - another remedy based on amoxicillin and clavulanic acid, which is available in tablet form, as well as the form of a powder for preparing a solution for parenteral administration, as well as a powder for receiving oral suspension. The cost of the funds is approximately 250-300 rubles.
• Ecoclave - a structural analogue that also contains clavulanic acid and amoxicillin in different dosages. The tool is considered no less effective, it helps to cope with severe manifestations of diseases. Its cost is approximately 280-290 rubles.

Any of the analogs can replace Flemoklav and costs a little less, but the use should be agreed with the doctor.

Means Flemoklav Solutab - effective and relatively safe, the disadvantage of which is the price. However, the dosage of the drug 1000 mg is considered the most popular in the treatment of adults. To get only benefits from the treatment, you should carefully study the instructions and follow all the doctor's recommendations.

Video about the analogue of Flemoklav

Instructions for use of the drug Amoxiclav: