Antibiotics of the cephalosporin series include drug Suprax, used to combat infectious diseases of the respiratory tract and other pathologies that were provoked by pathogenic bacteria. In pediatrics, this medication is actively used to treat bronchitis, tonsillitis, chronic pharyngitis and otitis media in children.
Before using the drug, you need to consult with a pediatrician who will help you choose the dosage of the drug, and also prescribe an effective treatment regimen.
Record content:
- 1 Forms of release and composition of the drug
- 2 Pharmacological properties
- 3 Pharmacodynamics and pharmacokinetics
- 4 Indications for use
- 5 Contraindications
- 6 At what age can the drug be used?
- 7 Instructions for use, dosage
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 Drug interactions
- 12 Analogs
- 13 Terms, conditions of sale and storage
- 14 Price
- 15 Video about the drug
Forms of release and composition of the drug
Suprax for children (the dosage of the drug depends on the diagnosed disease and the general condition of the child) can only prescribe a qualified doctor, since self-treatment of a rapidly progressing disease is fraught with the development of complications and related pathologies.
The drug is produced in 2 dosage forms:
-
Granules. The drug is intended for the preparation of a suspension. The granules have a round shape and are sold in small dark glass vials. After dissolving the medicine in water, a suspension is obtained with a sweet taste and a pleasant strawberry smell. For convenient dosing of the medicine, a plastic spoon is attached to the bottle, the volume of which is 5 ml.
- Capsules. The medicine is sold in cartons, each of which contains 1 blister with 6 capsules.
Additionally, pharmaceutical companies release the drug Suprax Solutab. This medicine is sold in tablet form. 1 package can contain a maximum of 10 tablets.
Cefixime is the main active ingredient of the drug. This component is micronized and used as a trihydrate.
Due to this, the active substance of the drug is not destroyed in the stomach, but enters the patient's intestines and enters the systemic circulation through the mucous membrane. 1 capsule contains 400 mg of the active ingredient, and 5 ml of suspension contains 100 mg.
As auxiliary components, the preparation includes:
- Cellulose.
- Strawberry flavor.
- Povidone.
- Silica.
- Dye.
- Hypromellose.
With regular use, the active substance of the drug inhibits the walls of pathogens, thereby preventing their further spread. In pediatrics, Suprax is in great demand due to the fact that in 95% of cases it is possible to do without a hospital to fight an infectious disease.
Pharmacological properties
Suprax for children (the dosage of the drug should be increased by an otolaryngologist or pediatrician, including if the child has been diagnosed with acute bronchitis) is prescribed for the treatment of respiratory diseases ways. The bactericidal mechanism of action of the drug is due to the fact that the constituent components are resistant to beta-lactamases.
The drug is effective against gram-positive and gram-negative bacteria.
For example:
- Intestinal, Haemophilus influenzae.
- Streptococci.
- Klebsiella.
- Salmonella.
- Proteus.
- Serration.
- Shigella.
- Gonococci.
- Citrobacter.
The drug is not prescribed in situations where Pseudomonas aeruginosa, listeria or enterobacteria have become the cause of the development of pathology. The bioavailability of the antibiotic is in the range of 40-50%. The effectiveness of the drug does not depend on food intake, but only prolongs the time to reach the maximum concentration of the active component in the patient's blood.
Suprax has a long half-life from the body, due to which it can be taken only once a day. The drug quickly enters the site of infection (for example, tonsils, sinuses, lungs), due to which it is possible to effectively stop the inflammatory process and reduce the intensity of the manifestation of painful symptoms.
Pharmacodynamics and pharmacokinetics
The drug has a bactericidal effect on the patient's body. Regular use of the drug allows you to achieve the death of bacteria that are highly sensitive to cefixime.
After entering the bloodstream, the components of the drug are evenly distributed over all tissues and organs, but their greatest concentration is recorded in the inflammatory focus. The drug is excreted from the body through the kidneys along with urine.
Suprax is an effective broad-spectrum antibiotic that does not cause adverse reactions at the correct dosage and is safe for children from the first days of life.
Studies have shown that in 90% of all cases, already on the 3rd day of treatment, patients notice a significant improvement feeling of well-being, which is due to a decrease in the inflammatory process, faster sputum separation, as well as a decrease in swelling affected tissues.
Indications for use
The wide spectrum of action of the drug Suprax allows the use of this antibiotic for the treatment of many pathologies and infections of bacterial origin. The medicine is used for the complex treatment of diseases of the ENT organs. The active component of the drug is effective in the presence of respiratory tract diseases, otitis media and infections of the genitourinary system.
In pediatrics, Suprax is prescribed for the treatment of the following diseases:
- Angina, which was provoked by streptococci.
- Sinusitis.
- Chronic sinusitis.
- Intestinal infections (eg, shigellosis).
- Pharyngitis.
- Bacterial laryngitis.
- Bronchitis, which is accompanied by attacks of severe coughing with purulent sputum.
- Gonorrhea.
- Pyelonephritis.
- Urethritis.
- Cystitis and other bacterial lesions of the urinary tract.
- Otitis media.
- Bacterial pneumonia.
In the annotation to the Suprax drug, the manufacturer indicated that cefixime is forbidden to be used to combat ARVI, chickenpox, mononucleosis and other viral diseases.
If the child has a sore throat, lymphadenitis or other warning symptoms for parents, then use a medicinal the remedy is possible only after prior consultation with the pediatrician, since the specialist must exclude the viral nature of the available diseases.
Contraindications
Suprax for children (the dosage of the drug can be increased by the pediatrician if the previously prescribed treatment did not bring positive results) will safe only if, before undergoing a long therapeutic course, the child undergoes a complete examination of the body so that the pediatrician is correct determined the diagnosis.
To reduce the likelihood of developing adverse reactions before use of the drug, you need to make sure that the following contraindications are absent:
- Renal failure
- Individual sensitivity of the body to the components of the drug.
- Colitis.
- The medicine in the form of tablets and capsules is prohibited for prescribing to children under 6 years of age.
When using the suspension to treat a child with diabetes mellitus, it must be borne in mind that the medicine contains sucrose, which can increase blood glucose levels.
At what age can the drug be used?
In pediatrics, Suprax granules are most often used, since this form of the drug can be used to treat children from the first days of life. In the finished form, the suspension has a sweet taste and a pleasant fruity smell. The pediatrician can also prescribe Suprax tablets to the child, which dissolve well in water.
But in this case, there are weight restrictions, since this form of the drug is prescribed only to those patients whose weight is less than 25 kg. The capsules can be used to treat adults and children over 12 years of age. This is due to the high dose of the active substance and the impossibility of dividing the capsule into several doses.
Instructions for use, dosage
Suprax for children (the dosage of the drug should be selected by the pediatrician, as it depends on the weight and age of the child, the diagnosis and the characteristics of the course of the disease) are most often prescribed in the form of granules, from which they are prepared effective suspension.
For these purposes, it is recommended to use still water without preservatives and sweeteners. It is forbidden to dissolve the granules in hot water.
In the process of preparing the suspension, the manufacturer of the drug Suprax recommends adhering to the following scheme:
- Shake the container with granules gently. To prepare a suspension, you can use Suprax Solutab tablets. To do this, it is enough to grind 1 tablet into powder and dilute the resulting product with water.
- 20 ml of still water is poured into a jar with granules. The bottle must be shaken several times to obtain a homogeneous mass.
- Add 20 ml of water to the jar again. The suspension should be allowed to stand for 10 minutes so that the granules are completely dissolved.
- Shake well before each use.
The finished suspension can be stored for a maximum of 14 days. After this period of time, the unused product must be disposed of. Suprax is an effective antibiotic that can only be taken after prior consultation with by the attending physician, since the safe treatment of a diagnosed pathology implies adherence to the exact dosage drug.
The dose of the drug is calculated based on the patient's age:
- For children under 1 year old, pediatricians prescribe 2.5-4 ml of suspension 2 times a day.
- If the child is 2 to 4 years old, then the dosage should be increased to 5 ml. The drug is taken in the morning, lunchtime and evening.
- For children from 5 to 12 years old, the suspension is given 3 times a day, 6-10 ml.
- For adults and children over 12 years of age, the drug can be taken 1 time per day at a dosage of 20 ml.
Treatment should last at least 10 days. If the prescribed drug therapy is interrupted ahead of time, then some of the pathogenic bacteria will not die, but will become resistant to the components of the drug.
The drug can be mixed with drink or food, as this does not affect the final effectiveness of the treatment. To prevent the development of dysbiosis and stomatitis, pediatricians recommend taking probiotics along with the Suprax antibiotic, which will help normalize the intestinal microflora.
Side effects
In 98% of all cases, Suprax is well tolerated by the patient's body.
But in isolated situations, the development of the following side reactions is not excluded:
- Digestive system: bouts of nausea, lack of appetite, vomiting, disturbed stools, dry mouth, dysbiosis, aching pain in the epigastric region, flatulence, pseudomembranous colitis, abnormalities in work liver.
- Urogenital system: vaginitis, recurrent itching and burning of the genital skin, interstitial nephritis.
- CNS: periodic dizziness, migraine, limb cramps, confusion, fainting.
- Hematopoietic system: accelerated destruction of red blood cells, aplastic or hypoplastic anemia, leukopenia, agranulocytosis, pancytopenia, neutropenia.
- Allergic reactions: itching and burning of the skin, urticaria, angioedema Quincke, systemic reaction with multiple organ failure and a decrease in blood pressure, syndrome Stevens-Johnson.
Long-term use of the drug Suprax can affect the results of laboratory tests. For example, the components of the drug increase the activity of hepatic transaminase and alkaline phosphatase enzymes in the blood, which may indicate damage to hepatocytes.
In the event of adverse reactions, further use of the drug must be discontinued and seek advice from a qualified pediatrician who will help you find a safer analogue.
Overdose
In medical practice, cases of overdose with the drug Suprax have not yet been recorded. But the manufacturer of the medicinal product admits that due to the significant excess of the recommended dosage in the patient may experience the following symptoms:
- Stomatitis.
- Eosinophilia.
- Development of hypovitaminosis B.
- Nausea, vomiting.
- Toxic epidermal necrolysis.
- Chills.
- Pseudomembranous enterocolitis.
- Flatulence.
- Acute renal failure.
- Erythema multiforme exudative.
- Dizziness, migraine.
- Hives.
- Stool disorder.
- Gastrointestinal tract candidiasis.
- Itching of the skin.
- Dysbacteriosis.
- Anaphylactic shock.
- Glossitis.
- Loss of appetite.
- Hyperemia of the skin.
- Aching pain in the abdomen.
It is possible to normalize the patient's condition only with the help of qualified doctors. To reduce the likelihood of further deterioration of the child's well-being, specialists perform gastric lavage and intestines, an effective sorbent and other drugs are prescribed for symptomatic therapy.
There is no specific antidote for neutralizing the active component of the Suprax antibiotic.
special instructions
Before buying Suprax capsules or granules, the parents of the child should carefully study the instructions for the medication.
To reduce the likelihood of developing adverse reactions and achieve a positive the therapeutic effect, the following recommendations should be taken into account:
- Long-term use of the antibiotic can lead to a violation of the intestinal microflora and the subsequent development of dysbiosis. If the drug treatment will last more than 10 days, then the patient must definitely take probiotics, or eubiotics (drugs that contain live bacteria necessary to restore microflora).
- The active substance Supraxa can affect the receipt of a false-positive result in a laboratory urine test for glucose levels. Coombs' reaction may also be wrong.
- If the patient is allergic to penicillins, then concomitant allergic reactions may occur in response to cephalosporins entering the body.
- The main component of the drug Suprax can react with other drugs. For example, Allopurinol, Carbamazepine, diuretics, and indirect anticoagulants. Combined therapy can be prescribed only by a qualified doctor who will exclude the possibility of a negative effect of drugs on the patient's body.
- Suprax contains sucrose, which should be taken into account by those who have been diagnosed with diabetes mellitus. Otherwise, prolonged use of the drug can significantly worsen the patient's condition.
The antibiotic Suprax is highly effective, due to which this drug is often prescribed for acute bronchitis and other infectious diseases, when the use of less powerful medications did not bring the expected therapeutic effect.
Drug interactions
If you take Suprax together with diuretics or penicillins, then an overdose is possible, since the concentration of cefixime in the patient's blood will gradually increase. Regular antibiotic use can affect the prothrombin index.
The components of the drug Suprax can increase the therapeutic effect of anticoagulants several times. With simultaneous use with antacids, the rate of penetration of cefixime into the systemic circulation is significantly slowed down.
It is forbidden to take Suprax together with diuretics, as this is fraught with impairment of kidney function. The antibiotic manufacturer recommends refraining from using aminoglycosides to reduce the likelihood of developing pyelonephritis.
Analogs
If there are contraindications, the Suprax drug should be replaced with a safer drug. Pediatricians recommend using effective 3rd generation antibiotics. Before using the drug, you need to study the instructions and consult with your doctor in order to reduce the likelihood of adverse reactions.
| Drug name | Description |
| Cefix | The drug is indicated for the fight against acute intestinal diseases, otitis media, uncomplicated urinary tract infections, acute pneumonia, tonsillitis, pharyngitis, sinusitis and acute bronchitis. Cefix is ​​prohibited from taking with individual sensitivity of the body to the components of the drug, as well as with porphyria. For children from 6 months to 12 years old, the drug is prescribed at the rate of 8 mg / kg of the child's body weight 1 time per day. For adults and children over 12 years of age, the drug is recommended to take 400 mg 1 time per day. The duration of treatment is determined by the attending physician. |
| Panzef | The drug is prescribed for diagnosed infectious and inflammatory pathologies provoked by pathogens that are sensitive to cefixime. Indications for use:
The main contraindications include hypersensitivity to the components of the drug. Pancef is recommended to be taken 2 times a day at 4 mg / kg of body weight. The course of therapy is designed for 7-10 days. |
| Ceforal Solutab | This drug is prescribed for the treatment of acute urinary tract infections, diseases of the ENT organs. The medicine is contraindicated in patients with porphyria, bronchial asthma. Ceforal Solutab is recommended to be taken 2 times a day, 200 mg. The course of treatment should last from 7 to 10 days. |
| Zinnat | The drug is used in traditional medicine to treat meningitis, sepsis, and respiratory tract infections. The drug helps to cope with:
Adults and children over 12 years old need to take 250 mg of the medication 2 times a day. The therapeutic course is designed for 7-10 days. |
| Augmentin | This drug is intended for the treatment of infectious and inflammatory diseases of the respiratory tract and genitourinary system. The drug is contraindicated in patients with hypersensitivity to cefixime. Augmentin tablets at a dosage of 625 mg should be taken 3 times a day, 1 piece. The duration of treatment depends on the patient's condition and the diagnosed pathology. |
Only the attending physician can choose an effective, safe analogue. Self-medication of infectious diseases is dangerous, since against the background of improperly selected therapy, the disease can progress, rapidly worsening the patient's condition.
Terms, conditions of sale and storage
All dosage forms of the Suprax antibiotic are sold according to a doctor's prescription. 
The shelf life of the drug is 3 years. Store the medication in a dry, well-ventilated place out of the reach of children. The room temperature should be between +15 and +25 C.
Price
You can buy Suprax both in a regular pharmacy and via the Internet. The cost of packing granules for preparing a suspension varies from 510 to 650 rubles. Only a qualified pediatrician can select a dosage of a medicine that is safe for children.
Parents of a child before buying a drug should study the instructions for use to make sure there are no contraindications. Only in this case will the treatment be effective and safe.
Video about the drug
Overview of the drug Suprax:
