Normaks (Normax) ear drops. Price, instructions for use, where to buy, reviews

Normax is a drug used to eliminate inflammatory and infectious processes in the body. The medication can be applied topically in the form of drops to eliminate ophthalmic (eye) and ENT (ear) pathologies.

And also orally in the form of tablets to eliminate diseases of internal organs, which are caused by the presence of pathogens. The product is popular due to its high efficiency and low price.

Forms of release and composition of the drug

The medication can be purchased in 2 dosage forms: drops and tablets. Drops are placed in 5 ml plastic or glass vials, which are equipped with a dropper.

The solution has a transparent consistency without impurities (there may be a yellowish tint), there is no smell. The tablets are produced in a round shape with a dividing line on the surface. The tablets are packed in foil blisters of 6 pcs. The cardboard box contains 1 blister.

Normax in the form of drops contains the following components:

Names of the components of the solution	Brief component annotation
Active substance
Norfloxacin	Possesses antibacterial properties with a broad spectrum of action.
Auxiliary components
Purified water	It is used to give the drug the desired concentration and as a binder.
Glacial acetic acid	The acid concentration is 96%, which provides antipyretic and anti-inflammatory action to the solution, and also enhances the antimicrobial effect.
Benzalkonium chloride	It has an antiseptic effect, helps to destroy not only viruses and bacteria, but also the fungus.
Sodium chloride	It is a binding element, and also helps to restore the water-salt balance.
Disodium edetat	Extends the shelf life of the solution

The active substance in the composition of the tablets is similar, the auxiliary composition has been changed to give the drug the desired shape. The drug is manufactured by an Indian pharmaceutical company.

Pharmacological properties

Normax belongs to a group of antibacterial drugs.

Pharmacodynamics and pharmacokinetics

Normax - ear drops, the price of which is considered budgetary. They are allowed to be used to eliminate ENT pathologies only after visiting a specialist.

The effective therapeutic effect of the drug is due to the following effect of the active substance on the affected tissues:

• physical processes in bacterial cells are suppressed, as a result their DNA and protein synthesis are disrupted, which leads to their death and the inability to reproduce. Not only active bacteria are exposed to the destructive effect, but also those that are in hibernation;
• the development of the inflammatory process is suppressed due to the action of glacial acetic acid and the reduction of the harmful effect of bacteria (toxins produced by microbes as a result of vital activity have a strong irritation on the tissue, causing the development of the process inflammation);
• by eliminating inflammation and killing bacteria, pain symptoms, itching and discomfort in the ears are reduced.

After instilling the solution into the ear tissues, the therapeutic effect is noted 1 hour after the manipulations and lasts up to about 12 hours.

A small part of the drug's components binds to proteins and enters the bloodstream. The metabolites, into which the components of the solution break down, are excreted from the body in the urine (approximately 30%) after about 4 hours. The remaining substances leave the body with sweat and feces.

Indications for use

The otolaryngologist may prescribe drops for ENT pathologies that are caused by infection and are accompanied by inflammation and soreness.

Disease data include:

• otitis externa. The disease is infectious in nature, with damage to the tissues of the external auditory canal. It is accompanied by inflammation, soreness and fever;
• acute otitis media. With this pathology, the infection often affects the tissues of the middle ear. The disease manifests itself with severe symptoms (high fever, soreness and severe swelling in the ear tissues);
• chronic otitis media. Mostly the tissues of the middle ear are affected. Symptoms may not be pronounced. In this case, there is a violation of the integrity of the eardrum. The presence of purulent discharge is possible from the hole;
• internal otitis media. The disease is only infectious. Bacteria are localized in the inner ear and not only disrupt its activity, but also cause a strong pain symptom;
• eustachitis. Pathology is expressed by the development of an inflammatory process in the auditory (Eustachian) tube. The cause of the development of the disease can be a prolonged runny nose;
• after removing a foreign object from the ear tissue. The solution prevents the penetration of infection into damaged tissues;
• the presence of trauma to the ear tissues. The drops also prevent the development of infectious diseases.

Also, drops are prescribed by a specialist before and after surgery on the ENT organs, to prevent the development of complications and accelerate the healing process.

Contraindications

Normax - ear drops, the price of which may vary depending on the type of pharmacy.

They cannot be used for therapeutic purposes in the presence of the following contraindications:

• intolerance or allergic reaction on the components of the solution;
• period of bearing a child. Drops Normax belong to a group of antibiotics that can cause impaired fetal development. Despite the fact that the data is not confirmed by tests, the use of the solution during this period is prohibited;
• lactation. A small fraction of the components enter the bloodstream and can pass into breast milk. As a result, for the period of using the drops, it is advised to temporarily stop breastfeeding the child;
• epilepsy. The likelihood of provoking the development of an attack by the components of the drug is not excluded;
• the presence of vascular pathologies in an acute form. The drug partially enters the bloodstream and can cause complications;
• the inflammatory process is caused by a fungal infection. The components of the solution have a detrimental effect not only on the pathogenic microflora, but also on the beneficial one, but they do not destroy the fungus. As a result, the use of drops will only provoke a deterioration in well-being.

Also, drops are not advised to be used for exacerbation of liver and kidney diseases, since the components of the drug increase the load on these organs.

At what age can the drug be used?

The drops contain a potent antibiotic, so it is not advised to use them until the child reaches 18 years of age. If other drugs for the treatment of ENT pathology are not suitable for a child, then the solution is allowed to be used from the age of one year, but only under the supervision of a specialist and according to an individual scheme.

Instructions for use, dosage

Normax is an antibiotic, so it is allowed to be purchased only after the appointment of a specialist. In this case, ear drops do not always need to be used according to the instructions.

Sometimes, depending on the severity of the course of the disease or in the presence of chronic pathologies, an individual course is required. Also, the features of the composition and use of the solution can be specified by the pharmacist in the pharmacy, along with the specification of the price.

In the absence of individual prescription, Normax drops to eliminate ear pathologies should be used according to the following instructions:

Pathology type	Recommended dosage	Duration of therapy
Otitis externa due to infection and eustachitis	It is required to instill 2-3 drops 4-6 times a day	The general course of treatment should last from 7 to 10 days.
Acute infectious otitis media	The solution should be instilled in 3 drops 8-12 times a day.	The duration of treatment is 10 days.
Chronic and internal otitis media	Instillation should be done 6-8 times a day, 2 drops	The duration of the course is 7 days.
Before / after surgery or for ear tissue injuries	The solution should be instilled 4-8 times a day, 2 drops	The duration of the use of drops is prescribed by a specialist, but should not exceed 10 days.

To speed up the achievement of the result, the use of ear drops is advised to be used in complex therapy.

When prescribing a solution by a doctor in childhood, it is not recommended to exceed the following dosages:

Name of the disease	Maximum allowable dosage	Duration of procedures
Otitis externa or eustachitis	It is prescribed 1 drop 2-3 times a day.	Duration of therapy - 5-7 days
Acute otitis media	It should be instilled in 1 drop 3-6 times a day.	Course duration - 7 days
Chronic and internal otitis media	The solution should be instilled 1 drop 3-4 times a day.	Duration of treatment - 5-7 days
After / before surgery or ear tissue injuries	Drops need to be instilled 1 drop 1-2 times a day.	The duration of treatment is selected individually, it should not exceed 7 days.

It should be borne in mind that the success of treatment depends not only on compliance the rules specified in the instructions, but also on the correctness of the manipulation:

1. The droplets must first be warmed to room temperature. To do this, you can hold them in a fist for about 10 minutes or put a bottle with a solution in a mug of warm water for about 5-7 minutes.
2. Next, the ear canal must be carefully cleaned of discharge (if any) and dirt using a special cotton swab. It is advised to moisten cotton wool in hydrogen peroxide or water for injection.
3. Place the patient on his side so that there is free access to the sore ear.
4. Open the bottle, slightly pull the auricle back or press on the tissue near the tragus (so that the medicine better penetrates the ear canal) and instill the solution with the indicated dosage. It is important, during the manipulation, to ensure that the dispenser does not come into contact with the tissues of the ear, as the sterility of the solution will be violated.
5. After instillation of the drug, it is required to maintain a position on the side for at least 2 minutes.
6. Next, plug the ear opening with a sterile cotton swab to create a thermal effect.
7. Close the bottle with a lid without touching the dispenser with your fingers.

It is important, if there is a deterioration in the state of health in children, it is required to immediately cancel the instillation of the solution.

Side effects

When used topically, Normax can cause the following negative reactions:

• temporary burning sensation;
• redness and dryness of the skin;
• an allergic reaction in the form of itching, tissue swelling or the appearance of a rash. In severe cases, Quincke's edema may develop;
• a feeling of ear congestion;
• impaired hearing quality;
• headache or dizziness, possibly a lack of coordination;
• violation of the process of falling asleep and the quality of sleep.

It is also possible that the activity of the kidneys and liver deteriorates if the drug was used for exacerbation of diseases of these organs.

Overdose

When using the drug Normax locally, cases of overdose were not recorded even with prolonged use or when the dosage was exceeded. Overdose with drops is possible in case of accidental ingestion of the solution.

In this case, the following symptoms may be observed:

• nausea accompanied by vomiting;
• repeated loose stools;
• sharp weight loss;
• severe pain in the digestive tract;
• loss of coordination and severe headache;
• the development of insomnia;
• fast fatiguability;
• violation of psychological balance in the form of an inexplicable feeling of anxiety, depression;
• Quincke's edema, severe itching, if the patient is allergic;
• yellowing of the sclera of the eye and skin. This symptom can be pronounced if there are chronic liver diseases;
• violation of the activity of the pancreas, liver and kidneys;
• exacerbation of chronic dermatological pathologies (if any);
• doubling of objects;
• ringing in your ears or hearing loss;
• violation of the condition of joints and bone tissue, expressed by painful movements;
• a decrease in the amount of iron and platelets in the blood;
• increased concentration of urea;
• convulsions;
• the appearance of cold sweats;
• loss of consciousness;
• violation of the functioning of the cardiovascular system;
• sharp swelling of the soft tissues of the face;
• increase in temperature indicators.

In case of accidental use of the solution, you should rinse the stomach and increase the intake of acidic liquids (for example, water with the addition of lemon juice) into the body to accelerate the removal of excess salts from organism.

special instructions

Normax - ear drops (the price of the solution can be announced by the ENT specialist together with the application funds), which is recommended to be used for medicinal purposes after getting acquainted with the nuances of therapy given means.

The subtleties of using drops include:

• before using the solution, it is advisable to determine the type of bacteria, since the drops do not destroy anaerobic bacteria;
• with severe pathologies of the hearing organs, it is advised to combine the use of the solution with the use of other antimicrobial agents orally;
• do not contaminate the dropper dispenser. For example, by touching with a hand or touching the tissues of the ear during manipulations, and you also cannot keep the bottle open for a long time;
• driving for 30-40 minutes is not advisable due to the possible development of dizziness;
• prolonged use of the solution can be addictive, as a result, the effectiveness of the drops will decrease;
• with the development of an allergic reaction or if the side effects do not disappear 30 minutes after using the solution, the drops should be stopped immediately.

The most important nuance is the use of drops only externally, oral use can cause an overdose of the drug.

Drug interactions

If it is necessary to use Normax drops in complex therapy, you should first take into account its compatibility with the following medicines:

• preparations with an acidic medium (with a pH value of 3-4) neutralize the effect of drops;
• if it is necessary to instill several types of drops, it is required to maintain an interval between procedures of approximately 40-60 minutes;
• medicines containing metals reduce the effectiveness of the solution;
• drops are not recommended to be combined with blood thinners, since Normax enhances their effect;
• the solution enhances the effect of medicines to reduce pressure, as a result, the indicator may drop to critical values.

Also, Normax drops reduce the effectiveness of antimicrobial drugs.

Analogs

Normax - ear drops, the price of which may vary in different regions, if necessary (allergy to the composition, lack of the drug in pharmacies, incompatibility with complex treatment) can be replaced with the following medicines:

Drug name, dispensing conditions and minimum price	Active substance and its action	Features of therapy
Tsipromed. Drops are dispensed by prescription, the price is from 130 rubles.	Ciprofloxacin, the active ingredient has antibacterial activity, but with a lower spectrum of action than Normax solution. The substance enters the bloodstream and breast milk, is excreted in equal proportions with feces and urine.	It is forbidden to use drops when carrying or feeding a child, as well as under the age of 1 year. The solution should be instilled 5 drops 3 times a day until complete recovery. After eliminating the symptoms, the drops must be continued to be instilled for another 2 days.
Norfloxacin. Drops are sold by prescription, cost from 110 rubles.	The active substance norfloxacin (the same as in Normax drops) helps to destroy a wide range of bacteria.	The tool is not used during pregnancy, lactation and in pediatric practice (up to 18 years old). It should be instilled in 1-2 drops 4 times a day for 7-10 days.
Sofradex. Prescription price from 600 rubles.	The active ingredients (gramicidin, dexamethasone and framycetin) provide antibacterial, anti-allergic and anti-inflammatory effects, and also eliminate severe itching.	In the presence of a fungal or viral infection, as well as in violation of the integrity of the eardrum, drops are prohibited for use. The solution should be instilled 2-3 drops 3-4 times a day for up to 7 days.
Otofa. Drops are sold by prescription, cost from 200 rubles.	The main component (rifamycin sodium) has anti-inflammatory and antibacterial effects.	Allergy is a contraindication and side effect of the drug. The agent should be instilled 5 drops 3 times a day for a week.
Anauran. Drops are dispensed by prescription, the price is from 300 rubles.	The multicomponent composition has a pronounced antibacterial and analgesic effect.	The solution should not be used if there is an allergy to the components of the solution. The drug for adults should be instilled 5 drops 2 times a day for a week. In childhood, you need to dose 2 drops 4 times a day for 5-7 days.
Candibiotic. Drops are sold by prescription, cost from 250 rubles.	The multicomponent composition has antibacterial, anesthetic, antifungal, as well as anti-allergic and anti-inflammatory effects.	Up to 6 years, if the tympanic membrane is damaged or if there is an allergy, drops are not prescribed. The solution should be instilled in 4-5 drops 3-4 times in knocks for 7-10 days.

It is important that the replacement of the solution is allowed after consultation with the ENT, since it is necessary to take into account the severity of the pathology and the presence of chronic diseases.

Terms, conditions of sale and storage

Normax drops should be stored at a temperature of 2 to 25 degrees, away from sunlight and children's reach.

Subject to these conditions, the shelf life in a sealed form will be 2 years from the date of production and 30 days from the moment the bottle is opened.

The solution can only be purchased at the pharmacy upon presentation of a prescription from a doctor.

Price

The price in pharmacies for Normax in the form of a solution for topical application varies from 150 to 200 rubles. In the Internet pharmacy, you can buy drops from 120 rubles, but it is important to make sure of the authenticity of the site and products.

Normax for ENT pathologies is a drug with high efficiency and low price. But since the drug is an antibiotic, it is not available commercially. It is important that during therapy you must strictly adhere to the instructions that come with the package with ear drops.

Author: Kotlyachkova Svetlana

Video about the active substance of Normax drops

Basic pharmacology of fluoroquinolones: