Sorbifer with low hemoglobin in adults. Reviews how to take during pregnancy

Sorbifer - it is an anti-anemic drug, which is indicated for admission to patients with low hemoglobin levels. The drug allows you to replenish the systemic iron deficiency, restore the stability of the cellular and biochemical composition of the blood without harm to the patient's body.

Treatment with medication is carried out by therapeutic courses with periodic tests for the level of hemoglobin and erythrocytes. The drug is used as an independent drug for mild anemia, or it is included in a complex medication course.

Forms of release and composition of the drug

Sorbifer is a drug that is produced in the form of round tablets covered with an additional layer of a protective film. The medication has a rich yellow hue, and one side of the tablet contains a branded engraving in the form of the Latin letter "Z".

Despite the presence of a protective shell, Sorbifer has a characteristic chemical odor, which is due to the presence of iron oxide. This antianemic agent is available in dosages of 100 and 60 mg.

The medicine is packaged in a bottle made of dark organic glass. Depending on the dosage of the drug, 1 vial may contain 30 or 50 tablets.

The bottle is closed from above with a plastic lid, which is equipped with a first opening controller and a special shock absorber.

The main package of the medication is a cardboard box, inside which there is detailed instructions for the use of this anti-anemic agent.

The table below shows the active and auxiliary components of Sorbifer, their quantitative composition and pharmacodynamic purpose.

Sorbifer composition	Biochemical properties of main and auxiliary substances
Ferrous sulfate	Ferrous sulfate is the active component of this drug, the dosage of which is 320 mg, which is equal to 100 mg of pure ferrous iron. This substance provides the main anti-anemic effect by stimulating the synthesis of additional red blood cells.
Ascorbic acid	Ascorbic acid is an active component of Sorbifer tablets, which is used for better absorption of iron compounds, as well as for improving the quality of blood. The mass fraction of this component is 60 mg.
Magnesium stearate	Magnesium stearate is used as an anti-caking agent, maintaining the dense structure of tablets even under conditions of long storage. The concentration of this component is 2.3 mg.
Povidone	Povidone is a safe preservative and chemical stabilizer. The mass fraction of this chemical does not exceed 51 mg.
Iron oxide (yellow)	Iron oxide is part of the protective film of Sorbifer tablets. This component performs an auxiliary function, and its presence provides the drug with a rich yellow color. The concentration of iron oxide is 0.4 mg.
Hard paraffin	Solid paraffin is an additional component of an anti-anemic agent, which is added to the composition of the protective film of the drug. The mass fraction of this substance does not exceed 0.1 mg.
Polyethylene powder	Polyethylene powder is an auxiliary component that stabilizes the structure of the drug. The dosage of this chemical compound is 20 mg.
Carbomer 934 R	Carbomer is an additional substance in Sorbifer tablets, which is used as a preservative for the chemical composition of the drug. The concentration of this component does not exceed 9.1 mg.

Sorbifer is a drug whose constituent substances provide the blood and tissues of internal organs with the necessary amount of nutrients, which is very important with low hemoglobin levels. The components of this antianemic agent are completely safe, do not possess toxic, mutagenic and carcinogenic properties.

Pharmacological properties

Sorbifer is an effective drug that is used for iron deficiency conditions in the blood.

Antianemic agent has the following pharmacological properties:

• takes an active part in intracellular oxidative processes;
• provides a gradual release of iron ions;
• promotes the formation of hemoglobin;
• reduces the manifestation of symptoms of iron deficiency anemia, improving the general well-being of the patient;
• saturates the body with an additional amount of ferrous iron and ascorbic acid, the presence of which ensures a stable metabolism, improves the quality of the cellular composition of the blood.

Sorbifer (with low hemoglobin, the medication is used in courses) is a drug that is prescribed only after a clinical blood test confirming the presence of iron deficiency anemia.

Pharmacodynamics and pharmacokinetics

The pharmacodynamics of Sorbifer is due to the action of ferrous sulfate and ascorbic acid. After these components enter the bloodstream, they quickly spread through the tissues of internal organs, penetrating through their cell membranes.

Iron takes an active part in the formation of new hemoglobin compounds, increases the quantitative composition of erythrocytes, and prevents the development of iron deficiency anemia. The modern technology for the production of Sorbifer tablets has made it possible to achieve a gradual release of iron ions, which ensures better absorption of this component.

Ascorbic acid takes an active part in oxidative processes that occur in the tissues of internal organs. This component improves the therapeutic properties of ferrous sulfate, improves the quality of the blood, improves the protective functions of the immune system.

The protective shell of Sorbifer tablets is inert with respect to the chemical components of gastric juice, but at the same time it breaks down under the influence of intestinal motility. At this moment, all the constituent substances of the anti-anemic agent are released.

Pharmacokinetics of Sorbifer is characterized by rapid absorption of its active components. Regular intake of 100 mg of the medication increases the concentration of iron in the blood and tissues of internal organs.

A distinctive feature of this antianemic agent is that the absorption of its main substances is 30% better than that of analogue preparations. Absorption of ferrous sulfate occurs in the duodenal cavity. The bioavailability of the main components is very high.

The connection of iron sulfate molecules with blood plasma proteins is within 90%, but it can also reach higher values. The half-life of the constituent components of Sorbifer is 6 hours. The metabolism of the drug occurs in the liver tissues.

In the process of cleavage of ferrous sulfate, chemical compounds are formed in the form of hemosiderin and ferritin. These metabolites are localized in hepatocytes, which may slightly reduce the functional activity of liver tissues. Myoglobin, which is also a half-life product of Sorbifer, accumulates in the tissues of the muscular system.

Indications for use

Sorbifer (with low hemoglobin, the drug is used as an antianemic agent) is indicated for use in the treatment of children and adults, who have been diagnosed with the following diseases:

• Iron-deficiency anemia (the drug is used as an independent means of therapy, or it is used together with more potent medicines);
• iron deficiencycaused by general depletion of the body, improper or inappropriate nutrition;
• anemia, the progression of which can lead to the development of complications during pregnancy or labor.

Sorbifer is indicated for men and women who donate blood or parts of internal organs. The medication allows you to eliminate acute iron deficiency, increase the level of hemoglobin and the quantitative indicators of red blood cells.

This antianemic agent can be prescribed to women during the lactation of a newborn baby with breast milk. Sorbifer is used by surgeons for faster recovery of patients who have survived surgery with a large blood loss.

Contraindications

Sorbifer (with low hemoglobin, the medication is used to improve the quality parameters of blood) contraindicated for admission in the presence of the following circumstances:

• individual intolerance to the main or auxiliary components of the drug;
• esophageal stenosis;
• obstructive processes affecting the walls of the digestive tract;
• hemolytic anemia;

  

• pathological conditions of the body, in which the physiological process of iron utilization is disrupted;
• the human body contains an increased concentration of iron compounds (in medical terminology, these conditions are called hemochromatosis, as well as hemosiderosis);
• children's age, when the child has not yet turned 12 years old.

Sorbifer is prescribed with extreme caution to patients who have ulcerative lesions of the gastric tract or duodenum, suffer from intestinal inflammation, ulcerative colitis.

At what age can the drug be used?

The drug Sorbifer is approved for use by children who have reached 12 years of age, or are older.

Instructions for use, dosage

It is forbidden to crunch Sorbifer tablets or break their protective film in any other way. The drug must be taken with ordinary drinking water without carbon dioxide.

Adults and adolescents from 12 years old

Patients of the adult age category and children who have reached the age of 12 years take the medication 1 tablet 1-2 times a day. Determination of the final dosage depends on the parameters of hemoglobin in the blood.

Patients with a severe form of iron deficiency anemia can be prescribed a dosage of 3-4 tablets per day, which are divided into 2 doses (the drug is used in the morning and evening). The average duration of a therapeutic course should be at least 3-4 months, but in general it depends on the dynamics to replenish the reduced hemoglobin.

Pregnant

Women who are carrying a child, as well as breastfeeding a newborn, take 1 tablet of the medication 2 times a day. This is the optimal dose for treating anemia. For prevention purposes, it is recommended to drink 1 tablet of ferrous sulfate per day.

The course of treatment is set individually, but to saturate the body with bivalent iron and restore normal hemoglobin levels, Sorbifer should be drunk for at least 3 months.

Side effects

Sorbifer is well tolerated by most patients of all age groups. Despite this, clinical trials of the drug showed that after taking of this antianemic agent, the following side effects may occur:

• nausea;
• various kinds of allergic reactions;
• damage to the walls of the esophagus;
• migraine;
• vomit;
• diarrhea;
• attacks of spasmodic pain in the region of the stomach;
• physical weakness;
• constipation;
• ulcerative lesion of the esophageal mucosa.

The main part of the side properties of Sorbifer is associated with dysfunction of the digestive system. If the above symptoms appear, you should stop therapy with this drug, and also inform your doctor about the incident.

Overdose

Violation of the rules for taking the drug with the use of large doses of Sorbifer can lead to general intoxication of the body, which is expressed by the following symptoms:

• pain inside the abdomen;
• nausea;
• cramps of the lower extremities;
• development of renal and hepatic failure;
• pallor of epithelial tissues;
• discharge of vomit;
• lowering blood pressure;
• excessive sweating;
• decrease in heart rate;
• acidosis;
• fast fatiguability.

To neutralize iron ions, you should drink 1 raw chicken egg or a glass of homemade milk, and then immediately go to the hospital. Patients with an overdose of Sorbifer are shown gastrointestinal lavage and symptomatic treatment. In especially severe cases, the introduction of Deferoxamine is indicated.

special instructions

During the period of treatment with this antianemic agent, darkening of feces is possible, which does not indicate a pathological state of the body. This is the reaction of the digestive system to the intake of large amounts of ferrous sulfate.

Drug interactions

The constituent components of Sorbifer tablets can reduce the absorption of the following drugs:

• Enoxacin;
• Levofloxacin;
• Clodronate;
• Tetracycline;
• Grepafloxacin;
• Penicillamine.

It is not recommended to carry out the simultaneous administration of Sorbifer with thyroid hormones, as this will lead to a decrease in the therapeutic efficacy of the latter substances. The use of antacids based on magnesium and aluminum can lead to a decrease in the absorption of ferrous sulfate.

The interval between taking this antianemic agent and medicines of other pharmacological groups should be at least 2-3 hours. Sorbifer is strictly forbidden to combine with Ofloxacin, Doxycycline, and Ciprofloxacin.

Compliance with these rules of drug interaction will allow for effective therapy of iron deficiency anemia with minimal risk of side effects.

Analogs

The following antianemic drugs are presented in pharmacy chains, which are used to eliminate iron deficiency, and are also analogues of Sorbifer:

• Aktiferrin - This is an effective drug that is produced in the form of oral drops and capsules, and its average cost is 930-950 rubles;
• Totem - this drug is produced in the form of a liquid solution for internal administration, and its price is 310 rubles. for 20 ampoules of 10 ml;
• Fenotek - This is an anti-anemic agent that is produced in the form of capsules (the average cost of a medication is 165 rubles. for 20 capsules);
• Ferrum Lac - These are chewable tablets based on ferric iron, which are produced by the Swiss pharmaceutical company Sandoz (the price of the drug is 820 rubles. for 90 tablets);
• Maltofer Is a pill form of medication intended for the treatment of iron deficiency anemia, which contains ferric hydroxide polymaltose in its composition (average cost of an anemic drug is 322 rub. for 30 tablets).

All of the above medications analogues should be prescribed only by the attending physician, who, based on the results of a diagnostic examination, established the fact that the patient has iron deficiency anemia.

Terms, conditions of sale and storage

The sale of Sorbifer is carried out on the basis of a doctor's prescription. It is necessary to store the medication in a dark and cool place, where the air temperature is within +20 degrees Celsius.

The shelf life of the medicinal product is 3 years, after which further pills are prohibited. Sorbifer should be left in a room out of the reach of children.

Price

The average cost of Sorbifer is 350 rubles. for 30 tablets.

Sorbifer is a safe drug for the complex therapy and prevention of hematological diseases associated with iron deficiency. The medication is available in the form of round tablets with a pronounced yellow tint. The drug is approved for use in children who have reached the age of 12 years, who have been found to have low hemoglobin levels.

For women who are in a state of pregnancy, as well as nursing a baby with breast milk, Sorbifer is prescribed for the prevention of iron deficiency states of the body. At the same time, the drug is absolutely safe and can cause a minimum number of side effects.

Video about the drug Sorbifer

Overview and description of Sorbifer tablets: