Wessel Douai F is used to thin the blood and preventing blood clots. If the fastest possible effect is required, then the doctors use the drug in the form of an injection solution. For independent use (when undergoing a treatment course), doctors appoint Wessel Duet F in the form of capsules, which are not only more convenient to use, but also their price is lower than for a solution.
Record content:
- 1 Forms of release and composition of the drug
- 2 Pharmacological properties
- 3 Pharmacodynamics and pharmacokinetics
- 4 Indications for use
- 5 Contraindications
- 6 At what age can the drug be used?
- 7 Instructions for use, dosage
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 Drug interactions
- 12 Analogs
- 13 Terms, conditions of sale and storage
- 14 Price
- 15 Video about the drug
Forms of release and composition of the drug
Wessel Douai F for oral administration is produced in the form of soft gelatin capsules with a dark red color. Inside the capsule there is a suspension of white color (a cream shade is possible). The capsules are packaged in transparent honeycomb plates of 20 and 25 pcs. The package contains 50,60 and 100 capsules.
Wessel Douai F capsules contain:
List of components | Description of the action of the components |
Active ingredient of capsules | |
Sulodexide (in the amount of 250 LE) | The substance prevents the formation of blood clots, promotes blood thinning, lowers the level of "bad" cholesterol, and the element dissolves already formed clots in the blood, normalizes blood circulation and the condition of the blood walls vessels. |
Additional components of capsules | |
Sodium lauryl sarcosinate | Improves the absorption of the main component by the tissues of the digestive tract. |
Colloidal silicon dioxide | It is an emulsion stabilizer, and also the element attracts pathogenic microflora (bacteria, allergens, decay products) and removes them from the body. |
Triacetin | It is used as a solvent and humectant and also has antimicrobial activity. |
Components of the capsule shell | |
Gelatin | The substance gives the capsule shell the required shape, and also protects the contents of the capsule from the action of gastric juice. |
Glycerol | The element is used as a binder, and the substance also has disinfecting properties. |
Sodium ethyl parahydroxybenzoate (preservative) | Preservatives, helps to extend the shelf life of capsules. |
Sodium propyl parahydroxybenzoate (preservative) | |
Titanium dioxide (bleach) | Substances give the casing the desired color and shade |
Iron oxide red (dye) |
The manufacturer of the drug is an Italian pharmaceutical company.
Pharmacological properties
Wessel Douai F is used to thin the blood and prevent blood clots. The drug belongs to the group of direct-acting anticoagulants.
Pharmacodynamics and pharmacokinetics
Wessel Douay F - capsules, the price of which is lower than for injection.
They affect the body:
- restore blood circulation in vessels and capillaries, and also normalize the condition of the walls of blood vessels (their thickness and permeability);
- help dissolve blood clots in the bloodstream;
- prevent the formation of blood clots;
- contribute to the normalization of metabolic processes in blood vessels, including diabetes;
- prevent the deposition of cholesterol in blood vessels and accelerate its excretion;
- promote blood thinning;
- additionally, the drug prevents the development of pathogenic microflora in the body.
After the drug is consumed, the capsule shell dissolves in the small intestine and the active substance is released. Further, the active element is absorbed by the intestinal tissues and enters the bloodstream. After that, Sulodexide is distributed in the walls of blood vessels and capillaries (providing the required therapeutic effect). The main substance is excreted from the body (with urine) approximately within 4 days after taking the capsule.
Important. Sulodexide is a natural component that is isolated from the mucous tissue of the small intestine in pigs.
Indications for use
Doctors prescribe Wessel Douai F capsules in the presence of the following deviations:
- violation of the state and functioning of blood vessels. It can be expressed by a strong spasm or vice versa by a strong relaxation of the walls of blood vessels;
- recent heart attack;
- diagnosing a deterioration in the blood supply to brain tissues. For example, ischemic stroke, as well as during the recovery period after a stroke;
- violation of the state and activity of the vessels of the brain caused by diabetes mellitus, regular increase in pressure or loss of elasticity of blood vessels;
- disruption of the nervous system due to impaired blood supply to brain cells;
- violation of blood flow in the extremities due to the overlap of a vessel (or vessels) by a thrombus (or thrombi);
- violation of the condition and functioning of veins, including thrombosis;
- with insufficient supply of oxygen and nutrients to the brain cells;
- violation of blood flow in the feet or palms due to diabetes mellitus;
- preeclampsia in pregnant women. Pathology is manifested by late toxicosis, swelling of the extremities, protein in the urine;
- prevention of the development of thrombosis with a tendency to this pathology.
Also, Wessel Douai F capsules are prescribed if the patient has too "thick" blood. In this case, the drug is recommended to be taken in combination with acetylsalicylic acid.
Contraindications
Wessel Douai F - capsules (the price per package can be announced by the doctor when prescribing the drug), which cannot be taken without consulting a doctor, and also in the presence of the following contraindications:
- tendency to hemorrhage even with minor injuries. Pathology is more often caused by increased "fragility" of blood vessels;
- diseases accompanied by a decrease in blood clotting;
- the initial stages of pregnancy (up to 12 weeks). At these dates, miscarriages often occur. Due to the capsules, the miscarriage will be accompanied by increased bleeding, and the patient may die from blood loss;
- intolerance to the components, as well as the presence of allergies to the components of the capsules;
- late pregnancy (especially before childbirth). Wessel Douai F will also provoke large blood loss during childbirth;
- in the presence of severe liver and kidney diseases, capsules can exacerbate pathologies.
Before planning surgical interventions, the medication should also not be used, as it can also cause a large loss of blood.
It is important that the possibility of using capsules during pregnancy and in children before the age of 18 has not been studied. Therefore, the use of the drug is possible only under the supervision of the medical staff and after the exclusion of contraindications.
At what age can the drug be used?
In the official instructions for the drug Wessel Douai F, age restrictions for use are not indicated. But it was noted that, if necessary, the use of the medication before reaching 18 years of age, the dosage the drug is selected individually, and the course of treatment is carried out strictly under supervision pediatrician.
Instructions for use, dosage
Wessel Douai F is strictly forbidden to use without a doctor's prescription. The specialist not only adjusts the dosage of the capsules (depending on the age and severity of the pathology), but also the duration of the medication intake (according to the dynamics of therapy). It is important that before the doctor prescribes the drug, the financial possibility of purchasing the drug is clarified, since the price for it is quite high.
Next, the dosage of Wessel Douai F in capsule form is considered, depending on the type and severity of the disease (for patients over 18 years old):
Pathology type | Single dosage | Frequency rate of admission per day | Notes (edit) |
Violation of the state and activity of blood vessels | 1-2 capsules | 1-2 | The course of therapy is 1 month. The frequency of taking courses per year is selected individually. If the functioning and conditions of the vessels are severely impaired, then it may first be necessary to use Wessel Douai F in the form of injections. |
Recent heart attack | 2 capsules | 1-2 | Depending on the patient's condition, before taking the capsules, the doctor may prescribe a course of injections by Wessel Douai F. The course of using the capsules lasts 20-40 days. |
Cerebrovascular accident | 1-2 capsules | 1-2 | The duration of treatment is 30-40 days. A repetition of the course is prescribed according to the dynamics of therapy. If necessary, the doctor may also prescribe injections of this medication. |
Circulatory disorders in diabetes | 1-2 capsules | 2 | The course of therapy can be 30 days and be repeated 2-3 times a year. In case of severe vascular lesions, the doctor prescribes an additional course of medication injections. |
Elimination of blood clots | 2 capsules | 2 | In a severe form of the disease, initially (approximately 14 days), the patient is prescribed injections by Wessel Douai F. Then the capsules are used for 30-40 days. If necessary, the course of treatment is repeated after 6 months. |
To thin the blood | 1 capsule | 2 | On average, the course of treatment lasts 1 month. Frequency rate of courses per year can reach 2-3 times. If the blood is very thick and there is a high likelihood of thrombosis, then the specialist will additionally prescribe injections of the drug. |
Gestosis | 1 capsule | 1-2 | The duration of taking capsules varies according to the dynamics of treatment. Wessel Douai F in the form of injections is rarely prescribed. |
Prevention of thrombosis development | 1 capsule | 1 | The duration of the capsule intake is 40 days. A repetition of the course is required in a year. |
Until the age of 18, the dosage of Wessel Douai F is not indicated in the instructions, since the rules for taking the medication are set individually.
Important:
- capsules should be used before meals (about 40-60 minutes);
- the drug must be taken with a sufficient amount of warm water;
- capsules must not be opened or chewed. Due to the integrity of the membrane, the release of the active substance occurs in the small intestine, where it is better absorbed and has a greater therapeutic effect.
When the drug is prescribed in the form of a solution for injection, the course of treatment takes place in a hospital. After transferring the patient to the capsules, the continuation of therapy is permissible at home.
Side effects
The course of using Wessel Douai F in oral form may be accompanied by the following side effects:
- headache, may be accompanied by impairment or loss of consciousness;
- congestion in the ears or severe dizziness;
- pain in the abdomen accompanied by nausea;
- vomiting or loose stools. The stool may turn black and have a pungent odor. Discoloration is characteristic in the presence of gastric bleeding;
- bloating in the lower abdomen, may be accompanied by flatulence;
- the appearance of blood in saliva or feces caused by the development of gastric or intestinal bleeding (noted in the presence of pathologies in the organs of the digestive tract);
- rash and itching on the skin. Symptoms are a sign of an allergy to the components of the product;
- mental disorders, manifested by a violation of the perception of the surrounding world (it seems distant and unreal);
- tremor of the limbs, both in a weak and in a strong form. Depends on the dosage of the medication;
- double vision, blurred vision;
- flushing of the face and palpitations;
- a decrease in the amount of urine per day due to compression of the urinary tract;
- pain and discomfort in the chest area;
- a decrease in the concentration of iron in the blood;
- subcutaneous hemorrhage. The symptom manifests itself with increased fragility of blood vessels;
- swelling of the tissues of the external genital organs;
- increased frequency of menstrual bleeding.
In rare cases, anaphylactic shock may develop (if the patient has a pronounced allergy to the components of the capsule). If at least one side effect appears, it is necessary to discontinue the use of the medication and visit the attending specialist to adjust the therapy.
Overdose
Wessel Douai F - capsules (the price for a course of treatment is quite high), which cannot be taken for a long time in large doses, and it is also forbidden to use more than 2 capsules at a time.
In case of an overdose of a medication, the following symptoms develop:
- the most common symptom is the development of internal or subcutaneous bleeding;
- fainting, including deep;
- severe abdominal pain due to the development of bleeding;
- profuse vomiting and bloody stools;
- Quincke's edema. If you are allergic to the drug;
- convulsions;
- very frequent palpitations and chest pain.
In case of an overdose of capsules, an emergency call for an ambulance is required and an injection of a 1% solution of protamine sulfate is required.
special instructions
When prescribing Wessel Douai F (in any form), the following recommendations must be observed:
- at the beginning of treatment, as well as after completing the course, it is necessary to donate blood to determine the rate of blood clotting;
- you should also determine the number of platelets in the blood;
- it is strictly forbidden to use the drug without passing a preliminary examination.
Taking capsules does not affect the quality of driving vehicles and performing hazardous work.
Drug interactions
Wessel Douai F - capsules (the price of the medication varies by region of sale), which cannot be used simultaneously with other drugs to reduce blood viscosity, as this therapy will increase the risk of developing internal bleeding. The use of the drug with other drugs has not been studied.
Additionally. It is strictly forbidden to combine the use of capsules and alcoholic beverages. Alcohol enhances the effect of the medication, as a result, the risk of bleeding (and other side effects) increases.
Analogs
In the absence of Wessel Douet F in pharmacies or the presence of intolerance to the components the following analogs are prescribed by doctors:
The name of the drug and its cost | The action of the medication and dosage | Notes (edit) |
Angioflux (injection and capsules) Sold by prescription 2300 RUB |
The active ingredient is similar to Wessel Douai F. Taking capsules is recommended to be combined with injections. The total duration of the course is about 50 days. | With a tendency to bleeding and during the period of bearing a child, the drug is not used. |
Gemapaxan (syringes with injection solution) Prescription RUB 1,500 |
The active ingredient anti-CA enoxaparin sodium has an anticoagulant effect. The dosage and course of treatment depend on the severity of the pathology, as well as on the content of the active substance in the solution. | Gemapaxan is not prescribed during pregnancy / lactation, under the age of 18, as well as in violation of the state of blood vessels and with a predisposition to bleeding. |
Fragmin (solution for injection) On prescription 1800 RUB |
The active element (sodium daltiparin) is an anticoagulant. The solution is available with different concentrations of the active substance. Therefore, depending on the concentration of the active element and the purpose of application, the course of treatment changes. | Despite the fact that the drug contains a fairly large list of contraindications, it is allowed to be used in pediatrics and during pregnancy. |
Fraxiparine (syringes with injection solution) Sold by prescription 3500 RUB |
Nadroparin calcium is an active ingredient, is an anticoagulant and prevents the development of thrombosis. Depending on the concentration of the active element in the solution, the dosage and duration of the treatment course change. | Up to 18 years of age, with lactation / pregnancy, as well as with severe pathologies of the liver and kidneys, the drug is not used. |
Clexane (syringes with injection solution) Sold by prescription RUB 3000 |
The active substance (enoxaparin sodium) has an anticoagulant and antithrombotic effect. The dosage and course of treatment depend on the amount of the active substance in the solution. | The drug includes an extensive list of contraindications, including pregnancy, children under 18 years of age, and lactation. |
Analogs should also be used after consultation and examination with a treating specialist.
Terms, conditions of sale and storage
You can buy Wessel Douai F capsules only upon presentation of a doctor's prescription with the indicated dosage and course of treatment. After purchase, the drug must be stored in a dark place at a temperature of 8 to 30 degrees. Subject to the listed conditions, the shelf life of the drug will be 5 years.
Keep the capsules out of the reach of children. Also, the capsule removed from the package should be taken within an hour.
Price
The cost of Wessel Douai F capsules depends on the amount of the drug in the package and the region of purchase of the product. Below is the price range for Russia.
Number of capsules in a package | Prices in pharmacies (rub.) | Prices in online pharmacies (RUB) |
50 | 2520 | 2470 |
60 | 2650 | 2590 |
100 | 4930 | 4750 |
When buying a drug over the Internet, you should check the site for authenticity so as not to become victims of fraudsters and not to buy a fake.
Wessel Douai F is recognized by doctors and patients as an effective drug for eliminating thrombosis and preventing their occurrence. Also, the capsules contribute to the normalization of blood circulation in diabetes mellitus. The high efficiency of the drug justifies its inflated cost.
Author: Kotlyachkova Svetlana
Video about the drug
Should I take Wessel Douai F and chime in preparation for IVF: