Diaflex tablets 50 mg. Price, instructions for use, reviews

Diaflex - effective tablets with pronounced anti-inflammatory properties, which are used for patients with various diseases of inflammatory origin. The price of the drug for a dosage of 50 mg is high, but it is justified, since it is considered effective, relieves symptoms and reduces the likelihood of complications.

Composition and form of release

The drug is available for purchase by patients in the form of oral capsules. They are also called tablets, as they are hard, gelatinous, have a standard shape, size.

The capsules are colored orange, placed in plates of 10 pieces. The blister and the description for use are placed in a cardboard box. When the capsule is opened, you can see a yellow powder inside it. The composition of the capsules includes the ingredient diacerin, which provides the main therapeutic effect.

In the composition, you can also see excipients:

• Gelatin.
• Dye.
• Magnesium stearate.
• Lactose in the form of monohydrate.
• Titanium dioxide.

These ingredients have no medicinal properties. The dosage of the main substance in 1 capsule is 50 mg.

Terms of sale, prices

Diaflex - tablets or capsules with a dosage of 50 mg, which are dispensed in pharmacies after presenting a form from a doctor. The price of the drug ranges from 900-1200 rubles. per packing.

The cost differs depending on the manufacturer's batch and the region of distribution.

Pharmacological properties

The medicine has anti-inflammatory and analgesic properties, as it belongs to the group of non-steroidal anti-inflammatory drugs. In this case, local antipyretic activity is observed, that is, the patient's body temperature decreases in the affected area.

Additionally, the agent reduces the likelihood of rapid progression of chronic diseases, improves the general condition, and reduces the number of relapses within a short period of time.

The complex effect of the capsules allows specialists not to prescribe a large number of other medicines to patients in order to increase the effectiveness of treatment.

Pharmacodynamics and pharmacokinetics

After entering the digestive tract, the capsule dissolves, and its active components spread through the blood, providing a therapeutic effect. The main substance blocks the activity of certain ingredients, which, under certain circumstances, lead to the development of a pronounced inflammatory process.

As a result, edema is eliminated in the affected area, blood circulation and tissue nutrition are significantly improved.

The drug also has another effect:

• Slows down the synthesis in the body of ingredients that provoke the rapid destruction of cartilage tissue. That is why capsules are actively used in the treatment of degenerative-dystrophic diseases of the articular joints. They help to slow down the progression of the pathological process.
• The tool also stimulates the production of components that have a positive effect on the process of cartilage restoration, which leads to an improvement in the condition of the articular joints, and facilitates movement.
• The medication has a pronounced analgesic effect, especially in the acute period, when any movements cause severe discomfort to the patient.
• In the area of ​​the lesion, it eliminates edema, the local body temperature decreases, which also leads to an improvement in the general condition.

After oral administration and distribution of the component through the blood, its concentration occurs in the cartilaginous, connective tissue, synovial fluid, which provides a pronounced effect in the area defeat.

The maximum therapeutic effect is observed only after 2 weeks of regular administration, since the medicine is a small amount accumulates in the body, which provides a long-term effect, even after discontinuation reception. There is an accumulation of funds in the bone marrow, bones, eyeballs, synovial fluid, kidneys, spleen, cartilage.

The processing of the substance of the composition takes place in the patient's liver. During the day, the metabolism and excretion of ingredients from the body occurs mainly with the help of the kidneys. In different patients, pharmacokinetic features may differ, which is associated with an individual response to a component of the composition.

Indications for use

Diaflex - tablets of 50 mg, the price of which is high, used in the treatment of diseases of the musculoskeletal system.

The main indications for the appointment:

• Osteoarthritis at the initial stage. The drug can be used as part of a complex treatment, which increases its effectiveness.
• Coxarthrosis. The condition leads to the development of degenerative-dystrophic changes in the cartilage tissue of the hip joint.
• Gonarthrosis with damage to the tissues of the knee joint. The medicine can be used as the main method of therapy.
• Degenerative-dystrophic changes in small joints. Usually, other drugs are used to treat such patients, but capsules can be used in severe pathological conditions.

The tool is not used for a single dose to eliminate acute symptoms, since the effect develops only with a course application.

Contraindications

The drug is not prescribed when diagnosing intolerance to any of its components, a tendency to such reactions in the patient's history.

Other barriers to therapy include the following conditions:

• Severe liver failure.
• Viral liver pathologies at different stages. With viral hepatitis, the processing of active ingredients deteriorates and slows down, and can provoke complications.
• Lactose intolerance and lactase deficiency.
• Internal bleeding of traumatic origin, as well as a condition that develops against the background of perforation of the wall of the stomach or intestines.
• Renal failure in acute and subacute form.
• Kidney pathology of infectious origin. The drug is not recommended for use in the acute stage, despite its anti-inflammatory properties.
• Acute disorders of cerebral circulation, impaired consciousness of the patient.
• Severe form of arterial hypertension.
• Acute myocardial infarction.
• Exacerbation of gastric ulcer, intestinal ulcer.
• Intestinal obstruction after surgery or against the background of the progression of adhesive disease.
• The period of gestation and breastfeeding. The drug negatively affects the course of pregnancy and the development of the child.
• The patient's age is up to 18 years. A potent agent can provoke acute complications in these patients.
• The period of rehabilitation after surgical interventions on the abdominal organs.
• Inflammatory pathologies of different parts of the intestine.

The drug is prescribed with caution to patients over 65 years old, which is associated with the presence in most cases of diseases of the heart, blood vessels, kidneys. Individual contraindications are determined during the examination of the patient.

Methods of administration and dosage

Diaflex - tablets 50 mg (the price of the product may be higher when purchasing a large package), or capsules taken orally as prescribed by a doctor. Taking into account the specific disease and the severity of its symptoms, the doctor determines the patient's treatment regimen.

With osteoarthritis

The drug can be used as an auxiliary method of treating osteoarthritis in patients who additionally suffer from osteochondrosis and other diseases.

The dosage per day for such a violation does not exceed 50 mg, that is, 1 capsule. For 2 weeks, the patient takes the drug in such an amount, after which he visits the doctor again. The specialist evaluates the result of therapy, extends the course up to 4 weeks. If negative reactions do not occur, and the effect of the treatment is persistent, taking the capsules can be continued for up to 3 months in a row.

The medicine is taken separately from food, washed down with a sufficient amount of liquid to accelerate dissolution and the onset of a therapeutic effect.

With arthrosis of large joints

When diagnosing degenerative-dystrophic changes in the cartilage tissue of large joints, the drug can be used for 4 months. The easy course of the pathological process does not require such long courses, that is, the medication can be used for 2-3 months.

The initial dosage per day does not exceed 1 capsule. After 3-4 weeks of regular use, the doctor re-examines the patient, evaluates the condition of the joints and general well-being. Based on the data of this examination, he decides to increase the dose. Often, the minimum rates are taken throughout the course of treatment.

If the therapeutic effect is weak, the dose is increased to 2 capsules per day. Moreover, it can be divided into 2 doses during the day, which ensures maximum efficiency, especially at night.

Side effects

Diaflex - tablets of 50 mg (the price of the drug differs in different pharmacies), which often provoke complications, even if all the recommendations of a specialist are followed. Disorders can affect only external tissues or affect the work of internal organs.

Damage area	Frequent negative reactions
Nervous system	From the side of the nervous system, disorders are often manifested. They are usually presented with headache and dizziness, sleep disturbances and increased irritability. Over the course of several days, there is an aggravation of symptoms, which leads to psychoemotional imbalance, impaired coordination of movements, and decreased performance.
Respiratory system	In patients with chronic respiratory diseases, disorders may occur with prolonged use of the medication. There is a dry, irritating cough, shortness of breath, especially pronounced during physical or emotional stress.
Digestive tract	The most pronounced symptoms are observed on the part of the digestive system. Patients report stomach pain and heartburn. Over a short period of time, these manifestations are joined by nausea and bouts of vomiting, flatulence and bloating, and upset stools. If there is a history of chronic diseases, there is an aggravation of their course, which only worsens the general condition.
urinary system	The urinary organs are rarely affected during therapy. Only sometimes do patients notice an increased frequency of urination and a change in the shade of urine. If the patient suffers from chronic diseases, the symptoms may appear in an acute form.
Skin and mucous membranes	Allergy to the drug often manifests itself, accompanied by classic symptoms in the form of rash and itching of the skin. Depending on the duration of use and the characteristics of the organism of a particular patient, the size of the lesions on the skin differs, as well as the presence of complications from the mucous membranes. Some patients note swelling of the eyelids, tissues of the nasal passages, and the oral cavity.

The emergence of complications is considered a reason for immediate refusal of treatment and a visit to the doctor. The patient may need special treatment to improve the condition.

Overdose

A single intake of a large number of capsules can provoke an overdose, which threatens the life and health of the patient. At the same time, there is an aggravation of all negative reactions, repeated vomiting during the day and suffocation, provoked by swelling of the mucous membranes of the throat.

The most dangerous manifestation of an overdose is gastrointestinal bleeding. It is accompanied not only by vomiting, diarrhea, discoloration of stool, but also by a critical decrease in blood pressure indicators. As a result, there is a threat to the patient's life.

If an overdose develops, it is important to see a doctor immediately. The patient may need gastric lavage and parenteral medication. In severe cases and untimely seeking help, it may be necessary to carry out surgical intervention on the digestive organs. It is forbidden to use any medication on your own in case of symptoms of an overdose.

special instructions

Diaflex - tablets of 50 mg, the price of which is high for many patients, prescribed with caution to patients with heart failure. This is associated with an increased risk of complications. Usually, such patients are advised to take no more than 50 mg of the drug per day, and the duration of the course does not exceed 3 months.

During the course of therapy, patients may notice pain in the stomach. It is not always considered a reason to refuse treatment. Perhaps the patient has any hidden symptoms of gastritis. In this case, the doctor usually prescribes means to prevent damage to the tissues of the stomach, for example, Omez.

If there is no therapeutic effect within 2 weeks of use, you must re-visit the doctor. Usually, it is necessary to select a different medicine, since the patient's body may not respond to treatment for various reasons.

Drug interactions

The drug must not be used simultaneously with other non-steroidal anti-inflammatory drugs, as the risk of complications from the digestive system increases.

It is allowed to combine therapy with calcium preparations, antibiotics, vascular agents, proton pump inhibitors. Simultaneous reception with laxative medications is not recommended.

Doctors draw the attention of patients to the fact that treatment simultaneously with antibiotics may slightly increase the likelihood of bowel complications. That is why it is recommended to combine use with medicines to normalize microflora.

Analogs

The drug has analogues with a similar and different composition. They can be used if it is impossible to assign it for various reasons.

Basic substitutes:

• Diartrin has a similar composition, but is cheaper than the original. The product is available in the form of capsules with a dosage of 50 mg of active substance. The action of the drug allows you to eliminate pain and symptoms of inflammation, it is not considered less effective, despite its domestic origin. Apply the remedy in long courses, like the original.
• Aertal contains another ingredient in the composition, but can be used as an analogue, since it belongs to non-steroidal anti-inflammatory drugs. The drug in the form of tablets for oral use quickly eliminates the symptoms of joint diseases, but does not affect the course of the pathological process.
• Movasin in tablet form, it has analgesic and anti-inflammatory properties, despite the different composition. The remedy is taken only in short courses, unlike the original. Prolonged use often leads to severe complications.

Some analogs may be less safe than the original, so they are taken in a minimum dosage and in short courses. In each case, you must first visit a doctor who will determine the appropriateness of prescribing a particular medication.

Storage conditions and periods

The drug may be stored in a dark and cool place, away from sunlight and children. The maximum storage time is 3 years.

After the expiration of this period, use is prohibited. The production date is indicated on the packaging.

Diaflex - effective tablets or capsules with anti-inflammatory and analgesic properties. They are prescribed more often with the defeat of the musculoskeletal system. The price of the drug for a dose of 50 mg is high, but many patients note that this is the only drawback of the medication.

Diaflex video

Diaflex capsules instructions for use: