Nakom( active ingredients of Levodopa + Carbidopa) is a combined drug that is used to treat Parkinson's syndrome and Parkinson's disease.
Since this drug is a complex drug, its use must be carried out under the strict supervision of the attending physician.
However, despite the fact that Nakom has a lot of side effects and contraindications, it has a high demand, because it has a high level of efficiency.
Contents
- Form release and components
- Pharmacological profile
- Indications and contraindications
- How to use the medicine
- Pregnancy and breastfeeding
- Possible side effects and overdose
- Overview of the doctor
- The voice of the people
- Purchase of the drug and its analogues
Form release and componentscomponents
The drug is available in the form of biconvex type oval-shaped tablets. Color tablets blue with white impregnations.
Tablets are contained in the cell plates, which are placed in a cardboard package.
Ingredients:
- active ingredients - levodopa 250 mg and carbidopa 25 mg;
- additional elements - starch, microcrystalline cellulose, magnesium stearate and dye.
Pharmacological profile
Nakom belongs to the group of anti-Parkinsonics.
Active ingredients of the drug:
- levodopa - a precursor of dopamine;
- carbidopa refers to inhibitors of decarboxylase aromatic amino acids.
Formula of Levodopa substance
The component of levodopa has an antiparkinsonian effect, which is achieved by converting the main component in the central nervous system into dopamine. This transformation provides a replenishment of the lack of dopamine inside the nervous system.
Due to this component, Nakoma's application provides relief from tremors, rigidity, salivation, hypokinesia, dysphagia.
Carbidopa is an inhibitor of the peripherally located dopa-decarboxylase. Due to carbidopa, the production of dopamine in the peripheral tissues decreases, as a result, there is an increase in the level of levodopa, which enters the nervous system.
The medicine begins to function in 24 hours. The full therapeutic effect occurs within 7 days.
Indications and contraindications
The drug Nakom is prescribed during therapy of Parkinson's disease and Parkinson's syndrome.
Also this medicine can be used to treat Parkinson's syndrome, which appeared against intoxication with toxic substances, methane poisoning, carbon monoxide and due to cerebrovascular diseases.
Nakom should not be used in the presence of the following conditions:
- during psychoneurosis;
- for severe psychosis;
- should not be used if there is a closed-angle glaucoma;
- in the presence of intolerance to the active component - levodopa, carbidopa;
- if there are skin diseases with unknown etiology;
- during melanoma;
- during the period of bearing of the child;
- with breastfeeding.
The drug must be used with caution during the following disorders and conditions:
- if there are disorders in the pulmonary system;
- in the presence of erosive-ulcerative lesions of the digestive tract;
- during epileptic seizures;
- for bronchial asthma;
- myocardial infarction, in which there are violations of the heart rhythm;
- during severe hepatic pathologies;
- for kidney disorders;
- for endocrine diseases in decompressed forms;
- during diabetes mellitus;
- for chronic heart failure.
How to use the medicine
According to the instructions, the daily dosage of the drug Nacom is determined in a strictly individual order. It also depends on the primary therapeutic effect. Dose adjustment can be done during the treatment.
Initiation of treatment should be done with a minimal dose - half the tablets one or twice a day. To achieve a therapeutic effect daily or every other day, the dosage should be increased by half the tablet. The average therapeutic dosage is 1-2 tablets per day.
Admission for Pregnancy and Breastfeeding
How does the drug Nakom on women during pregnancy is unknown. According to studies carried out on animals during the application of a combination of carbidopa and levodopa, visceral and skeletal disruptions occur.
Use the medicine at the time of pregnancy is in cases where a positive action for the mother will be much higher than the expected harm for the unborn child.
Do not use when breastfeeding. Data on the isolation of active components with breast milk are not available.
Possible side effects and overdose
During the application of Nakom, numerous side effects can occur:
- problems with the nervous system - the occurrence of dizziness, drowsiness, paresthesia, sleep disturbances in the form of insomnia, confusion, dementia, seizures, possibly depressivea condition during which suicidal thoughts, increased libido and excitement, the emergence of mental states with hallucinations may appear;twitching of the muscles, blepharospasm;
- disorders of the digestive system - often there is a state of dyskinesia and nausea, anorexia, diarrhea, vomiting, the appearance of bleeding GIT, sometimes there may be a state of dysphagia, dyspepsia, flatulence, excessive dryness in the mouth, the appearance of a bitter taste,abdomen, hiccups, constipation;
- in rare cases may occur darkening secretion of sweat glands, alopecia, rash, diplopia, vision disorders;
- sometimes appears incontinence or urinary retention , urine may become dark;
- is often observed condition of arrhythmia , frequent heartbeat;
- various allergic reactions .
During an overdose, all side effects increase.
Sometimes there may be an arrhythmia condition. In this disorder, a special antiarrhythmic therapy is performed.
Review of the doctor
Nakom is an anti-Parkinsonian remedy that has an effective effect, but not a safe one. Active components quickly penetrate into the bloodstream and affect the nervous system. In general, the drug is prescribed for elderly people with Parkinson's disease.
The application of this drug provides the recovery of the nervous system in Parkinson's syndrome, passes all the unpleasant symptoms characteristic of this disorder - tremor of hands, head, a person can safely move without a stick.
Take the drug is strictly according to the instructions, you should start taking it with a half tablet, then the dose gradually rises. The use should be carried out only under the strict supervision of a physician.
The doctor neurologist
The voice of the people
What common people think of Nakoma, you can learn from the reviews.
Nakom was prescribed to my mom for Parkinson's disease. There were times when she simply could not hold a glass of water or tea in her hands. The hands were shaking violently, so the whole content just poured out.
I do not know where she got this disease, but how many problems it did not convey in words. Therefore, when the doctor appointed to take the drug Nakom, I immediately bought it. After the application, my mother was much better - went shaking hands, head, she could walk calmly without support. This is an effective remedy, although there are many side effects.
Marina, 45 years old
Mom is 56 years old and already she has trembling limbs. I immediately turned to the neurologist, so that he could examine her and prescribe a treatment. After the examination, the doctor diagnosed Parkinson's disease. She was prescribed a comprehensive treatment, which includes Nakom.
Despite the high cost, I bought this medicine. After the application began, noticeable improvements appeared. True, there were small problems with vision, and as a whole, an effective tool.
Svetlana, 39 years
Purchase of the drug and its analogues
The price of packing tablets in 100 pieces in pharmacies ranges from 1400 to 1600 rubles, and also the analogs of Nakom are available for purchase: 
- Madopar;
- Sindop;
- of levodopa and carbidopa;
- Left;
- Tidometh Forte;
- Tremonorm;
- Sinemet.
