Glycine Forte is a drug from a group of metabolic, nootropic, sedatives. Glycine is an interchangeable neurotransmitter amino acid, and the receptors with which it binds are located in the brain and spinal cord.
When the amino acid binds to the receptors, there is a weakening effect on the neurons, increases the release of GABA( gamma-aminobutyric acid), which causes inhibition( inhibition) of nerve impulses, which has a neuroleptic effect and is recommended for use in abstinence syndromes of various genesis.
In the spinal cord, glycine causes a slowing down of motoneuron impulses, which makes it possible to use the drug in nervous diseases, to reduce muscle tone.
Glycine Forte from Evalar improves the metabolism in nerve cells, which leads to improved memory, speeds up thinking and facilitates work.
Contents
- Glycine VS Glycine Fort: Is there a difference?
- Pharmaceuticals
- Mechanism of action
- When to take the
- remedy Restrictions for the use of
- Dose and dosage regimens
- Overdose cases
- Special instructions
- Expert opinion
- Patient feedback
- Purchasing and storage
- What else is there in the market?
Glycine VS Glycine Fort: Is there a difference?
Both preparations contain one active protein substance, but in Glycine Fort it is two and a half to three times more than in Glycine. 
Glycine Forte may also additionally contain vitamins B: B1, B6, B12( from Evallar), which have neurotropic effects, and improve the effect of the drug on the body, it is more convenient to use, since it should be taken less often, at the expense ofincreasing the dose, hence buying it is much more profitable, despite its high price, since its effectiveness is much higher.
Pharmaceuticals BAA
The drug normalizes metabolic processes in cells, and also possesses neuroprotective, sedative and anti-stress effects on the body.
The drug easily penetrates into most of the extracellular space of the body, as well as through the blood-brain barrier.
The enzyme complex, which is synthesized in hepatocytes, cleaves glycine into carbon dioxide and water, which allows for its easy elimination. The drug is not cumulated.
Glycine Forte consists of:
- aminoethanoic acid( glycine) - 300 mg, B1 - 5 mg, B6 - 6 mg, B12 - 0,009 mg( Evalar);
- glycine - 250 mg;
- aspartame 0.4 mg;
- Copovidone 9.6 mg;
- Croscarmellose sodium - 0.1 mg;
- magnesium stearate - 2 mg;
- sorbitol - 7.9 mg( Canonfarma production).
The preparation is available in the form of round tablets of a whitish color, sweet to taste, for resorption.
Mechanism of action
Aminoethanoic acid is an interchangeable neurotransmitter amino acid that is constantly synthesized in the human body.
The mechanism of operation of which is to attach the mediator( glycine) to the receptors( which are encoded by the GLRA1, GLRA2, GLRA3 and GLRB genes) that are located in the brain and cause inhibition of nerve cells, the release of activating amino acids( eg, glutamic acid) decreases, GABA( inhibitory neurotransmitter amino acid), which causes sedation.
Group B vitamins are involved in the synthesis of phospholipids, which are used in the construction of the myelin sheath of nerves, which contributes to the regeneration( repair) of nerve cells.
When should the
be taken When should the medication be used:
- With nervous diseases that are not accompanied by obvious damage to the structure and integrity of the brain, but affecting its functions. They are manifested by human agitation, insomnia and instability in the emotional plane, instability of their emotions( psychoneurosis, pseudo-neurotic conditions, vegetovascular dystonia).
- Diseases of the nervous system that are accompanied by damage to the structure and integrity of the brain .
Diseases of this group can occur after trauma, transmitted infectious and inflammatory processes of the brain( meningitis, meningoencephalitis, encephalitis, brain abscess), parasitic infection( cysticercosis). - Hemorrhage into the brain substance or lack of blood circulation in a specific area of the brain( ischemic stroke).
- Encephalopathy of hepatic, alcoholic, perinatal and other genesis.
- Dyssomnia( insomnia) .
- To improve brain function during increased use of .
Restrictions on the use of
Under what conditions can not the drug be used:
- intolerance of the constituents of the drug;
- people with low blood pressure( BP) should carefully apply the medicine, and regularly measure blood pressure;
- women in any period of pregnancy( and also if they are breastfeeding) should take the medicine only after permission from the doctor.
Dosage and dosage regimens
The tablet of the drug must be absorbed under the tongue or behind the cheek( sublingually or buccally).
How to take Glycine Forte, depending on the condition of the patient:
- If the patient has memory impairment, asthenic syndrome, decreased performance, anxiety and fear, unstable emotional state , then take ½ tablets( 150 mg) in the morning and evening, the coursefrom two to four weeks.
- In case of of vegetative dystonia, neurosis-like states, neuroses, neurasthenia, brain lesions of organic genesis( ischemic disorders in the CNS, meningitis, encephalitis, TBI) with a component of emotional inconstancy, insomnia, anxiety, adults( also children over 3 years)should take ½ tablet twice a day for 14 days, and then, if necessary, repeat the course. Children under 3 years take ¼ tablets 2 times a day for 2 weeks, and then 7 more days - a quarter tablet only once a day.
- If the patient complains of sleep disorder ( falling asleep or quality) - you need to use half the tablet in the interval of 5-20 minutes before going to bed.
- In case of ischemic stroke , the patient must consistently dissolve 3 tablets at once in the first six hours from the onset of the disease, and then five days to suck 1 tablet 3 times a day. After that, he takes one tablet twice a day for a month.
In the future we are talking about the possible treatment of alcoholism, but in the schemes it is not yet available.
Cases of overdose
In adults, when the recommended dose is exceeded, the following are possible:
- head pain;
- nausea;
- feeling of discomfort in the abdomen;
- weakness;
- scattering of attention;
- dizziness;
- lowering blood pressure.
Children after taking a high dose may experience syncope( loss of consciousness) due to hypotension and drowsiness.
Allergic reactions may occur.
Special instructions
With special precautions, prescribe medication for people with arterial hypotension under the control of blood pressure. If blood pressure decreases, the drug should be stopped.
Before starting treatment, consult a physician.
The drug is compatible with alcohol. Used in the treatment of alcoholism.
In appointing glycine Forte, along with drugs that suppress depression and antipsychotic drugs, the side effects of the latter decrease.
If you appoint a dietary supplement for prolonged therapy with neuroleptic, hypnotics or a tranquilizer, there will be a summarizing effect of inhibition of excitation in the nervous system.
Expert opinion
Reviews of doctors will help to draw conclusions about the effectiveness and safety of the Glycine Forte from Evalar.
Used Glycine Forte for the treatment of a concomitant disease. The patient had arterial hypertension and neurosis. After a two-day intake of the drug, immediately noted the positive dynamics, which allowed to adequately treat the underlying disease.
Petr Vladimirovich, physician-therapist
Repeatedly I resort to the prescription of this drug. I note the positive impact on the nervous system and the body of my patients. Increases the level of B vitamins, improves overall condition and performance. The patient experienced a rapid regression of negative symptoms after an ischemic stroke.
Inna Valerievna, general practitioner
The patient, 62 years old with a neurosis-like condition, who was treated in the department of neurology and psychiatry, had a clear effect on the use of Glycine forte.
The inhibition of excitation was observed, the concentration of attention was improved and the mood was stabilized, which is not unimportant in the treatment of neuroses.
Alexander Konstantinovich, neuropathologist
Patient's comments
Public statements of ordinary people.
I drink the drug every day before going to bed for 1 tablet, to facilitate falling asleep, as well as during the day, before important meetings, and during special experiences. The drug does it perfectly. Finally, I can fall asleep at night and do not spin until 3 o'clock.
Anna, 42 years old
Only with the help of glycine, I finally managed to forget about my panic attacks. I drank a lot of different drugs with little efficiency. At the last appointment the neurologist recommended me glycine fort, which I drank 2 times a day. After a week of using, I forgot about my problems forever. I drink it to this day.
Natalia, 61 year
For two weeks I was terribly worried about the feeling of fear, anxiety, could not sleep peacefully, this provoked constant stress at work, at home and in my personal life. A friend advised the drug Glicin Forte, she herself drank in similar situations.
I started to drink the drug, I felt relieved, I finally had a good sleep and I stopped feeling so much. Feeling of fear and anxiety decreased significantly.
Tatiana, 45 years old
I really like Glycine Fort, unlike the simple Glycine, which I had to take three times a day and acted not earlier than a week or two, he showed himself much better and more efficiently.
Glitzin-forte from the company Evalar, I took only twice a day, and a calming and relaxing effect, it immediately on the day after the start of treatment. In addition, the preparation is enriched with vitamins of group B, which increases its effectiveness. I recommend!
Alena, 28 years old
The drug does its job well.
According to the experience of practical application, it suppresses feelings of anxiety, internal fears, calms the patient with a sedative effect and simultaneously concentrates his attention and improves memory, showing his nootropic effect.
And also a good sleeping pill, to which there is no addiction. Patients remain satisfied after treatment.
Purchase and storage of
The medicine is available in the form of 250mg and 300mg tablets for 10, 20, 30, 60, 90 or 100 pieces, which are intended for resorption.
Price Glycine forte depends on the volume of packaging:
- 300mg 20 tablets ( Evalar) - 55-80 rubles;
- 250mg 30 tablets ( Canonfarma Production) - 50-75руб;
- 300mg 60 tablets ( Evalar) - 124 -150 rub.
To save the medicine, it should be placed in a dark and dry place, where direct sunlight can not enter, at a temperature below 25 ° C.Tablets should be stored in a place where children do not have access.
Released without medical prescription.
What similar is still on the market?
The following analogues and analogues of the Russian production of the Glycine Forte dietary supplements are available in pharmacies:
- Mexidol is a medicament from the group of antioxidants, shows a stabilizing effect on cell membranes, improving trophism in
neurons. It occurs in the treatment of vegetovascular dystonia, ischemic diseases of the central nervous system, encephalopathies, and also with coronary heart disease. - Glycised is a drug that has a soothing, nootropic effect on neurons of the brain. It is accepted for asthenic syndrome, TBI, disorders of blood supply to the brain.
- INTELLAN - is used in the sense of anxiety, fear, overexertion and increased fatigue, with depression, as well as in the dispersion of attention. The composition includes natural extracts from medicinal plants. Improves cerebral circulation.
- Dormiplant - a soothing remedy with valerian and melissa extracts that can improve sleep quality, is a good tool for feeling anxiety and stress.
- Sedavit - used for neuroses of various origins, neurasthenia, vegetovascular dystonia, increased irritability and nervousness. Apply two tablets three times a day.
