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The use of Tauredin injections for arthritis of various origins

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Taureledon Tauredon helps with various forms of arthritis. The drug has a direct effect on the focus of inflammation and prevents its further spread.

It is advisable to use this remedy only as directed by a physician. Also, you need to carefully study all the recommendations listed in the instructions.

Contents of the article

  • Formulation and Composition
  • Pharmacological properties of
  • Indications and contraindications for use
  • How to apply injections
    • Scheme of application for adults
    • Therapy of pediatric patients
  • Adverse events and overdose
  • Drug interaction
  • Practical experience is the basis of truth
  • Purchase of a drug and its analogues

Form and Composition

The preparation is available as a solution for injection with dosages of 10 mg, 20 mg, 50 mg. The solution is contained in ampoules of 5 ml. Ampoules are placed in a package of cardboard base. One package contains 10 ampoules.

One ampoule contains the active ingredient - sodium aurothiomalate. Its dosage can be 10.20 or 50 mg.

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Pharmacological properties of

Tauredon is a basic drug that is used during the treatment of pathologies of the autoimmune type. It is part of the Taureledon group of gold preparations. Has anti-inflammatory, immunosuppressive effect. The level of gold content is almost 46%.

The inhibition of stimulation of lymphocytes of antigen-induced type, suppression of phagocytosis with monocytic and granulocytic type of flow, stabilization of lysosomal type membranes, as well as strengthening of fibers from the collagen structure with occupying sites of immune-active type, which are capable of inducing an autoimmune type process, occur under the influence of the active constituent element.

Clinical efficacy of the drug occurs approximately between 9 and 17 weeks, when the total level of the active component will be between 300 and 800 mg.

Indications and contraindications for the use of

Tauredon is given at the following indications:

  • for rheumatoid arthritis;
  • with juvenile arthritis;
  • for the therapy of arthritis in psoriatic form.

The drug can not be used during the following conditions:

  • if there is an increased sensitivity to the constituent components of the drug;
  • for a multivalent allergic reaction;
  • during anemia;
  • for pancytopenia;
  • in the disturbance of kidney function;
  • during disorders of liver function in severe form;
  • for pulmonary tuberculosis in active form;
  • for various collagenases - lupus erythematosus of a systemic nature, periarteritis of the nodular type, with periarteritis, scleroderma, dermatomyositis;
  • during ulcerative colitis;
  • in complicated diabetes mellitus;
  • to pregnant women;
  • when breastfeeding.

How to put the injections

The therapeutic therapy of Tauredon consists of three phases: the

  • phase of the trial type , it consists in determining the tolerability of the drug, in the selection of the dosage;
  • phase of the saturated type ;
  • phase of maintenance therapy .

It should be noted that the dosage regimen should be determined by the doctor only according to the individual characteristics of the patient's body.

Scheme of use for adults

It is necessary to inject injections 1-2 times in 7 days and only strictly according to indications:

  • 1-3 injections in a dosage of 10 mg;Introduction of injection
  • is further done with 4 to 6 administration of 20 mg;
  • with 7 injections - 50 mg 1-2 times in 7 days or 100 mg once a day in 7 days before bringing the total dose of gold to 1.6-2 grams.

When clinical efficacy is achieved, it is possible to switch to maintenance therapy of 50 mg Tauredin once every 14 days or 100 mg once every 30 days.

This therapy is maintained for a long period depending on the condition.

Therapy of pediatric patients

Scheme for the treatment of children:

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  • at 7 days, one injection is given at a dosage of 0.7-1 mg per kilogram of weight until reaching the saturated phase;
  • with maintenance treatment is done at 1 mg per 1 kg of weight 1-2 times in 30 days.

During the treatment with this drug, it is necessary to constantly monitor laboratory clinical indicators of urine and blood tests. And also you need to do biochemical blood tests, which reflect the condition of the liver and kidneys.

Adverse events and overdose

During the use of the drug, the following side effects can occur:

  • manifestation of cholestasis;
  • state of pancreatitis, enterocolitis;
  • symptoms of hepatonecrosis;
  • sometimes there may be symptoms of stomatitis;
  • occurrence of thrombocytopenia, leukopenia, pancytopenia, aplastic anemia, eosinophilia;
  • manifestation of agranulocytosis, exanthema, gingivitis;hematuria
  • signs of cylindruria, hematuria, proteinuria;
  • the state of alopecia, photosensitization;
  • surveillance of bronchiolitis, alveolitis, fibrotic pulmonary disease;
  • symptoms of red squamous lichen;
  • appearance of signs of conjunctivitis, Au deposits in the cornea, ulceration of the cornea, peripheral neuropathy( "golden" encephalopathy), neurotoxic changes in the eye;
  • manifestation of itching, scabies, redness, rash, dermatitis.

When taking the medicine above the prescribed dose, the following symptoms may appear:

  • headaches;
  • fever;
  • lowering blood pressure;
  • manifestations of ischemic ECG changes;
  • state of nausea;
  • occurrence of pain in the abdomen;
  • appearance of a rash on the surface of the skin.

In case of an overdose, treat with symptomatic therapy.

Drug Interaction

Phenylbutazone The drug Tauredon is not compatible with Phenylbutazone, Metamizol sodium, cytostatics, photosensitizing drugs.

Penicillamine has a detrimental effect on the effectiveness of the drug, increases renal excretion, increases the risk of side effects from the hemopoiesis and kidneys.

Myelotoxic drugs increase the appearance of signs of hematotoxicity of the drug.

Touredon should not be treated with aminoquinolines, d-penicillamine, small immunosuppressants, sulfasalazine.

Practical experience is the basis of the truth

After examining the opinions of specialists and patients about the drug Tauredon, it is possible to draw certain conclusions.

Arthritis in various forms is very difficult to cure, because this pathology threatens with deep joint damage, which often turns into a chronic form.

All the patients I appointed to Tauredon were satisfied and note that after the second phase of their application their condition improved much - joint pains, edema, inflammations came down. And already at the end of treatment the disease completely recedes. But I would advise before applying it to see a doctor and undergo a complete examination.

Physician rheumatologist

Tauredon is indicated in the treatment of arthritis in various forms. It quickly eliminates the main symptoms, namely pain, inflammation, swelling, and also prevents further spread of the lesion.

This medicine is well tolerated. Despite the presence of a large number of side effects, they almost do not manifest. Before its application it is necessary to pass inspection on which basis the doctor will appoint or nominate the scheme or plan of application of a medicine.

Therapist doctor

I have rheumatoid arthritis for 5 years already. He appeared at me after the second birth. During periods of exacerbation, I have severe pains, it happens that I can not walk normally, sit, bend down. Any movement causes infernal pain.

After another aggravation, my husband sent me to a doctor for examination. During the examination, the doctor prescribed the use of the drug Tauredon. He prescribed a scheme of use, which I adhered to for almost 2 months. After the full course of pain disappeared, the disease does not bother me for 2 years.

Margarita, 39 years old

I have been bothered with arthritis for 10 years already. It arose because of increased physical exertion. I have long been involved in sports, often had to do weight training, which sometimes led to injuries. As a result, this led to the appearance of arthritis.

When I had an exacerbation of arthritis, I just could not stand these terrible pains in the joints and called the doctor. After the examination, the doctor prescribed the application of the Tauredon drug and additionally painted its scheme of application. I used it for 2 months. As it's not strange, the pains have all passed, and arthritis has not bothered me for 1 year already.

Sergey, 45 years old

Purchase of a product and its analogues

The price of one package of Tauredon with 10 ampoules is from 13,200 to 17,000 rubles, and cheaper analogues of the drug are also available: Zavedos

  • Sodium arotimolate;
  • Zavedos;
  • Zedex;
  • Zeptol;
  • Indomethacin;
  • Intrazoline;
  • Iphietsef;
  • Ambrosan;
  • Kapastat;
  • Cardiwas;
  • Kwamatel.

Always consult a physician when changing a drug.

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