Hormones And Biochemistry

Elevated prolactin and conception

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The ability to conceive is greatly influenced by the hormonal background. All women with a diagnosis of "infertility" and with a suspicion of him must necessarily pass an analysis for hormones. First of all, the level of prolactin, regulating lactation, is considered.

If you want to conceive a child a high level of hormone makes it impossible. For successful conception, it is necessary to lower it. Elevated prolactin may indicate a microadenoma of the pituitary gland, causing infertility. However, not always an elevated level of this substance has a close relationship with the lack of ovulation.

The desired pregnancy will occur if there is a corresponding hormone in the blood. Failure of indicators in either direction affects the monthly cycle of a woman, inhibits maturation of the egg. With an excessively high level of prolactin, amenorrhea can be provoked when menstruation is completely inhibited. The hormone also interferes with the normal functioning of the yellow body producing progesterone.

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Indicators of analysis of

Blood test

If the analysis recorded an elevated level of the hormone, the doctor pays attention to the numbers. Multiple increase may be a symptom of a microadenoma. If the norm of prolactin is exceeded slightly, you should pay attention to macroprolactin. If he is elevated, then one can plan for conception.

Indicate macropolylactin in assays in approximately, in percent. The hormone rate depends on the cycle phase:

PHASE Ng / mL μME / mL
Follicular 4.5 - 33 136 - 999
Ovulatory 6.3 - 49 190 - 1484
Luteal 4.9 - 40 148 - 1212

During the childbearing age it is especially important to monitor the level of prolactin in the blood so that you can get pregnant without problems. The norm during this period varies within 40-600 mU / l .The ideal level of prolactin for conception in a woman should be within 120 - 530 mU / l .

Reasons for increasing prolactin

To date, medicine identifies 2 main causes that affect the increase of the hormone in the blood:

  1. Physiological:
    • sexual intercourse;
    • lactation;
    • long sessions of massage;
    • the use of medicines;
    • hypoglycaemia;
    • sexual intercourse;
    • stimulating the nipples;
    • intrauterine device;
    • scraping, surgery, trauma;
    • physical activity;
    • stressful situations.
  2. Pathological:
    • of the hypothalamic disease;
    • pituitary disease;
    • cirrhosis;
    • estrogen-producing tumors.

Diagnosis

If you find a symptom that indicates an elevated level of the hormone, you should be examined by a doctor. Diagnosis includes:

  • X-ray of the head;
  • plasma research;
  • examination of the fundus;
  • tomography.

How to reduce prolactin

Doctor

Elevated hormone does not allow a woman to become pregnant. If the excess hormone level is caused only by the pituitary adenoma, then further examination and treatment is not carried out, since a similar tumor occurs in every 10 people.

If the increased rate is caused by malignancies, then the doctor may prescribe an operation or drug therapy. In some cases, the operation can be replaced by radiotherapy or chemical.

Treatment is carried out with drugs that suppress prolactin - dopaminomimetics: lizard, dostinex, parlodel .Reception of medicines spend a long period, preparing for conception. Only with prolactinomas, medication is prescribed for life. If during the gestation of the fetus it is necessary to reduce prolactin, the norm of which is constantly increasing, then bromocriptine is prescribed.

Planning pregnancy

It's no surprise that you can get pregnant with an increased prolactin. Only relatively recently, in order to become pregnant, it was necessary to lower the hormone without fail. His norm should be within certain limits, so as not to cause an early termination of pregnancy. Before using the necessary medications, an endocrinologist should be consulted, since it is a question of changing the hormonal background.

With the task of restoring the ability to conceive, reduce prolactin in the blood and normalize the menstrual cycle, dofaminomimetiki cope perfectly. In addition:

  1. is recovering pulsatile secretion,
  2. is stimulated by ovulation,
  3. disappears symptoms of a lack of female hormones:
    • excess hair,
    • acne,
    • puffiness,
    • excess weight.

Pregnancy with increased prolactin

Dopaminomimetics may be withdrawn after a successful conception. The basis is the decline in the growth of hormone levels. However, since tumor growth does not always stop, after conducting a number of necessary tests, a pregnant woman can be prescribed bromocriptine.

In general, increased hormone in no way affects the course of pregnancy. There is no evidence of pregnancy failure from an overabundance of prolactin. No complications were observed during childbirth.

However, there is a risk of death of a newborn, if the mother had to take bromocriptine throughout the pregnancy. The fact is that prolactin in the fetal body is involved in the maturation of the surfactant - a substance covering the alveoli from the inside.

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