For normal health and uninterrupted operation of all systems and organs, it is necessary that all metabolic processes function normally.
The drug Rocaltrol( Rocaltrol) helps to regulate the exchange of calcium and phosphorus, which allows to guarantee the strength of the skeleton and the absence of problems with ODA.Refers to the group of vitamins and supplements, includes such important substances as vitamins D and A. The main active ingredient is calcitriol.
The drug is a capsule. They are soft and opaque, oval in the gelatinous shell. Color - brown - red.
Packed in vials made of dark glass for 30 and 100 pcs.
Article content
- Pharmacological action
- Pharmacokinetics and mechanism of action
- Indications for use
- Restrictions for prescription
- Instructions for use
- Cases of overdose
- Interaction with other drugs
- This is important!
- Practical experience of consumers
- The opinion of the doctor
- Conditions for the purchase and storage of the drug
Pharmacological action
The basic substance is an important and the most active metabolite of vitamin D. It also promotes the rapid absorption of calcium through the digestive tract and its entry into the bone.
The effect of the drug after a single application lasts for 5 days. Exchange processes consist of stimulation of activity of cells and bone tissues.
Pharmacokinetics and mechanism of action
Absorption of components is carried out in the intestine. The process can last up to 5-6 hours. In the blood it concentrates in plasma proteins.
Calcitriol formula
The elimination process occurs after 9 hours.
However, the pharmacological effect of using the drug Rocaltrol in a 1-fold dose lasts an average of 1 week.
Calcitriol is also excreted in bile, and is also processed in the liver and intestines.
With urine, up to 6-7% of the substance is excreted, with feces up to 25-27%.
If there is a kidney disease, then the level of calcitriol in the blood serum will be significantly lower than normal.
Indications for use
The drug is prescribed in the following cases:
- some forms of osteoporosis;
- osteopenia;
- kidney disease( kidney failure, renal osteodystrophy);
- various forms of hyperparathyroidism;
- rickets in any of the forms;
- is a phosphate-based diabetes.
Before using the drug, it is absolutely necessary to consult a specialist.
Restrictions on the prescription of
Prohibition of the use of the drug if:
- is diagnosed with hypercalcemia and all diseases accompanied by this process;
- hypersensitivity( allergic manifestations) to the drug as a whole or to any of its components;
- excess of vitamin D and its derivatives in the body at the time of treatment initiation;
- infant age and children under 3 years.
With great care, the drug should be used if it is diagnosed:
- atherosclerosis;
- pulmonary tuberculosis in closed form;
- various vascular diseases;
- problems with heart and blood flow;
- phosphate nephrolithiasis.
It is also not recommended to use the tool for the elderly.
Instructions for Use
ROCALTROLL is taken by mouth with a dosage of 0.25 μg, unless otherwise indicated after the examination. The daily dose is selected according to the individual scheme, which depends on the calcium content in the serum.
It is important to remember that the treatment process should begin with a minimum amount of funds and constantly undergo examinations that allow to detect the level of calcium in the serum.
If hypercalcemia is diagnosed, serum calcium and phosphate levels must be determined each day. Sometimes dosage is reduced or increased, for example, in postmenopausal osteoporosis in women, it is 0.25 μg 2 times in 24 hours. The course of treatment is up to 1 month.
Secondary hyperparathyroidism suggests that the initial daily dosage will also be a minimum dose of 0.25 μg for adults per day.
However, in some cases, it can be increased solely by the doctor's decision to 0.5 μg. Hypoparathyroidism and rickets are also treated with a dose of 0.25 μg. Duration of treatment is 14-30 days.
Cases of overdose
To determine that there was an overdose of Rocaltrol it is possible for the following symptoms:
- weakness;
- drowsiness;
- weight loss;
- headache of varying intensity;
- nausea;
- vomiting;
- disorder of the digestive tract, expressed by constipation or diarrhea;
- the appearance of thirst, sometimes very strong;
- apathy for no apparent reason.
Consequences of overdose can be expressed in violation of the kidney and heart, as well as lungs and pancreas.
Treatment of an accidental overdose begins with a gastric lavage, which should not be delayed, or taking special medications that cause vomiting.
It is recommended to use the most common petroleum jelly to remove the components of the medicine from the body - it has a soft but guaranteed laxative effect and allows the components to escape naturally.
If elevated levels of calcium persist, substances such as phosphates and corticosteroids can be used to stabilize the condition as soon as possible.
Interaction with other drugs
During the use of the drug, it is required to stop taking other medications or supplements containing vitamin D in any form.
Admission together with diuretins increases the risk of hypercalcemia, therefore, one of the drugs will have to be abandoned.
With preparations containing digitalis, one should also be more careful, since interaction with Rocaltrol can cause arrhythmia.
Drugs or dietary supplements with magnesium can, together with a vitamin D-containing agent, cause hypermagnesemia, so it is better to cancel a joint dose or to calculate the minimum dose. The same should be done with medicines containing phosphates.
This is important!
During treatment with Rocaltrol it is best to observe a strict lactose-free diet, respectively, to exclude the use of dairy products, since they contribute to the additional intake of calcium into the body, which at the moment is harmful to the body. Low mobility promotes the development of hypercalcemia.
Patients with normal renal function should avoid dehydration. Special care should be taken when prescribing the drug to children under the age of 18 years.
Negative impact on the ability to drive vehicles and work with machines and mechanisms does not occur.
Practical experience of consumers
Reviews of patients who take the drug Rocaltrol.
The use of the drug Rocktalrol began not so long ago. After the operation, a lack of calcium and a violation of metabolic processes.
One course has already passed, so I can say - the drug really works. The dosage was chosen as minimum according to the doctor's recommendation. Now analyzes show the norm for all indicators. I am very pleased with the result of the treatment, I recommend.
Marina, patient
After the beginning of taking the drug according to the doctor's scheme, there were unpleasant symptoms in the form of gravity in the abdomen and pains in the liver.
The reception had to be temporarily stopped, the calcium values did not change( low).
Svetlana, patient
Improvements after the course of taking the drug came almost immediately, there were no side effects, but I did not break doses and specially applied a diet with complete lack of milk.
In the beginning, only a little nauseated, but the next day it all passed. Impressions are positive, the tests are normal. I recommend to use, but only after diagnosis and consultation with your doctor.
Nina, patient
Doctor's opinion
I have a medical education, I work as a doctor in a polyclinic, so I often come across people who have problems with metabolic processes.
I think that the drug Rockaltrol is effective, the main thing is not to violate the recommended dosages, because they take into account the individual characteristics of the individual patient.
Peter, physician-therapist
Conditions for the purchase and storage of
The drug belongs to the list B. The drug should be stored indoors, at a temperature of no more than 25 ° C.It should be 
dry.
It is best to choose a place protected from light, must be protected from heat and direct sunlight. Shelf life is 36 months. Do not use if the period has expired.
From pharmacies is released without prescription. Cost from 620 to 720 rubles depending on the region. Analogues of the drug Rocaltrol - Osteotriol and Silkis.
