Problems with joints can occur at any age, so you need to know in advance how to restore their performance, restore mobility and get rid of unpleasant or painful sensations.
Miakaltsik, produced in a convenient form of spray and injection, allows you to quickly and efficiently restore the phosphorus-calcium metabolism, the violation of which leads to complex diseases of OD, including osteoporosis and osteopenia.
Contents of the article
- Pharmacological action
- Pharmacokinetics of the
- medication Indications for use
- Dosages and regimens for admission
- Overdosage and additional indications
- Opinion of doctors and patients
- Purchase and storage of medication
Pharmacological action
The effect of the drug components is to suppress the activity of osteoclast hormones. This is due to the effect on specific receptors, which significantly reduces the rate of bone tissue exchange, leading biochemical processes back to normal.
Simultaneously, the speed of recovery processes increases, which is indispensable in such complex diseases as osteoporosis.
The drug acts as an active analgesic, affecting all types of pain. Studies conducted by specialists showed that after a single administration of the agent, a biological reaction manifests itself by an increase in the excretion of calcium, phosphorus and sodium, while the excretion of hydroxyproline decreases.
Prolonged administration of the drug leads to an increase in bone density, which reduces the risk of fractures or development of bone disease by more than 35%.
Pharmacokinetics of the drug
The drug actively begins its work, hitting the mucous membranes of the nose - enough 40 minutes to feel relief, in for an hour a person forgets about the great pain. This method of exposure is on average 4% more effective than taking analgesics in the form of tablets.
Based on the results of the research it was found out that if the recommended dose is exceeded, the concentration of substances in the blood actively acting on the cause of poor health will increase, and the bioavailability of the drug will remain at the same level. Distribution - the agent does not penetrate the placental barrier.
There are no data on the penetration into breast milk at this stage of the study. Excretion occurs naturally, begins within 30 minutes after use.
The preparation contains the main active ingredient calcitonin salmon, obtained by a synthetic method. Excipients:
- sodium chloride, benzalkonium;
- is hydrochloric acid;
- water.
Produced in packs of 14 doses.
Indications for use
The doctor prescribes the use of the drug Miakaltsik in the following cases:
- treatment of osteoporosis;
- pain in bones of varying intensity;
- osteitis deforming;
- is a neurodystrophic disease, including reflex degeneration, humerus syndrome, and neurotrophic disorders.
No specific contraindications to its use have been identified during the use of the drug and at the research stage. The reason for the refusal of admission is the individual intolerance of the components that make up the drug.
Dosages and dosage regimens
The drug is administered intranasally in an amount not exceeding a dose of 200 IU.If the remedy is shown to be preventive, vitamin D can be added to this dose.
The period of admission and its duration is determined by the doctor, therefore, preliminary consultation should be mandatory.
If the main reason for taking the drug is pain in the bones and joints, which are based on such diseases as osteolysis, osteopenia, the drug is prescribed daily at a dose not exceeding 400 IU for 24 hours.
If a dose of 200 IU is indicated, it can be taken at a time, unless otherwise indicated by the examiner.
It is important to remember that completely pain can disappear after 1-3 days, so do not independently increase the dosage of the drug.
Also, if the treatment time is delayed, it is necessary to gradually reduce the amount of the drug and increase the interval between doses.
Sometimes a doctor can prescribe a doubled dose of a medicine, for example, to treat Paget's disease. Duration of admission in this case is at least 3 months.
Sometimes the disease treated with the drug can return - in this case it will be necessary to take the remedy at the dose prescribed by the specialist.
In case of neurodegenerative diseases treatment should be started as soon as possible. The approximate dosage is 200 IU / day once a month.
Overdosage and additional indications
The excess of the drug intake is expressed by the following symptoms:
- nausea, vomiting;
- tides;
- pressure drops;
- dizziness.
According to the doctors' observations, cases when the overdose was 600-800 ME are known, but there are no negative consequences - this indicates that the symptoms of an overdose do not appear in every patient and depend on the individual characteristics of the organism.
It is also known that if the recommended doses are exceeded, hypocalcemia may develop with manifestations in the form of paresthesia or muscle twitching. In this case, specific and urgent treatment will be required - most often the doctor prescribes the abolition of the drug and prescribes symptomatic therapy, with the subsequent development of hypocalcemia it is recommended the use of injections of calcium gluconate.
In addition, there is a high probability of allergy and anaphylactic shock( in rare cases).That's why before using the drug should be skin tests.
Doctors very rarely resort to the appointment of Miakaltsik for the treatment of children under 15 years of age, so there is no full information and recommendations on the use of the drug in childhood and the consequences of an overdose.
For elderly people, no changes in dosage or drug tolerability have been noted. A similar situation is observed among patients with renal dysfunction, but no specialized studies have been performed to date.
It is not recommended to apply the drug if it is planned to perform complex works requiring concentration of attention. It is also better to exclude the management of a motor vehicle for the time being to avoid problems and emergency situations on the road.
As for the interaction of the drug with other drugs, there is no exact information, since no studies were conducted. To better assimilate and reduce the risk of side effects, alcohol consumption should be completely ruled out.
It is better not to start taking the drug during pregnancy and during the period of feeding, as its effect on the body and fetus is not revealed, since there is no data on this issue.
Experiments on animals, which were conducted by specialists, showed that the agent does not penetrate the placental barrier.
Opinion of doctors and patients
Comments of consumers and doctors who use Miakaltsik in their practice.
Taking the drug has made it easier for me to postpone the recovery period after the fracture. The doctor advised Miakaltsik as a means to relieve pain. The course of admission was 2 weeks.
The result is above average, the pain did not go away completely, but it was much easier to carry. In general, the impressions are positive.
Serge, 41
I am a practicing surgeon. Miakaltsik is a good alternative to many modern medicines, as it does not contain chemical components that negatively affect the health of internal organs. I recommend it as an anesthetic, as well as a restorative aid for bone diseases.
Nikolai Valerievich, 47
Receipt of funds should be strictly on the recommendation of a doctor. Self-medication and dosages calculated independently can only harm - it is checked by own experience. I used a spray for three weeks - there were complications of osteochondrosis.
I tried to increase the dose - I got nausea and slight weakness, I went back to the recommendations - everything is fine. Unpleasant feelings have passed, mobility has recovered. I recommend.
Elizaveta Vasilevna
Purchase and storage of medicament
The product is on the list B. The closed package of the drug should be stored in the refrigerator at a temperature of at least 2 ° C, do not freeze .Shelf life is 3 years.
After start of use, the temperature should not exceed 25 ° C.Completely complete the treatment after opening the package is recommended for 4 weeks or not to use the product after this period.
Do not store the drug in the refrigerator. Optimum storage of the bottle vertically to prevent leakage.
Keep out of the reach of children. From pharmacies is released on prescription. The price of Miakaltsik is on average 950 rubles.