The drug Osteogenon is available in tablets and belongs to the group of drugs that regulate the metabolism in bone tissue, while replenishing it with a lack of calcium.
The main component of the drug is an active-acting ossein-hydroxyapatite compound, which contains:
- collagen;
- non-collagen proteins;
- peptides;
- calcium;
- calcium hydroxyapatite;
- phosphorus;
- other organic constituents.
Article Contents
- Pharmacological action
- Pharmacokinetics means
- Indications
- Contraindications
- mechanism of action on the application
- detailed instructions on dosages
- Overdose and the additional guidance
- Side effects
- Cautions
- Reception during pregnancy and lactation
- Doctors advise
- Walking through the hospitalchambers
- Tips for receiving patients
- First aid for fractures
- Purchase question
- Substitution of
Pharmacological action
Forming the structure of bone tissues, the drug affects the phosphoric-calcium metabolism.
Intensive osteogenesis and normalization of the mineral composition of bones additionally have a positive effect on the metabolic processes in the joints.
Pharmacokinetics of
When calcium is absorbed in the gastrointestinal tract, parathyroid hormone is produced, which reduces the possible bone resorption that oppresses the negative effects of osteoclasts. Phosphorus crystallizes the necessary building materials in bone tissues and delays the excretion of calcium by the kidneys.
Indications for use
The drug is used with: 
- the presence of cracks and bone fractures to enhance the processes of revitalization;
- pregnancy and lactation in case of violation of calcium-phosphorus balance, with osteopenia;
- osteoporosis caused by hyperthyroidism or hypreparathyroidism, as well as arthritis;
- osteoporosis caused by involuntary immobilization of the limb.
Contraindications
If the patient is under the age of 18, the drug is not prescribed.
Not used Osteogenon in hypercalciuria, with renal insufficiency, with individual intolerance of the drug components and during hemodialysis.
Mechanism of action
Treatment and prevention of osteoporosis with the help of osteogenon is carried out by influencing the production of osteoblasts and the inhibition of osteoclasts.
The calcium contained in the preparation enters the body, but its excretion by the kidneys slows down, thanks to the phosphorus contained in the tablets, which crystallizes the hydroxyapatite.
Osteocalcin binds calcium, strengthens and crystallizes bone tissue. Also in the formation of new bone tissue, collagen and ossein, substances from the formulation are involved.
Instruction for use
Osteogenone is prescribed to adults at the maximum dose for the diagnosis of osteoporosis and in smaller doses when other pathological processes are present in the body.
Duration of treatment with the drug varies specifically depending on the condition of the patient
More on the dosages of
In osteoporosis, the recommended dose of the drug is higher than with other diagnoses.
In osteoporosis, a physician can prescribe for adult patients up to 4 tablets twice daily , whereas in other diseases it is recommended that no more than two tablets per day be taken.
Overdose and additional instructions
If the recommended dose of the drug is exceeded, the body does not become intoxicated, but it is recommended to perform blood calcium levels in the patient's urine for the detection of hypercalcaemia and hypercalciuria.
Side effect of
Osteogenon caused minimal negative responses, is well tolerated by patients, the occurrence of single allergic reactions and gastrointestinal disorders is associated with individual intolerance to patients of the auxiliary substances that make up the drug.
Special instructions
The drug can be used by patients with arterial hypertension, the content of sodium chloride in it is minimal. The combination of the use of osteogenone with thiazide diuretics is not recommended, as the risk of hypercalcemia increases.
Moderate alcohol intake does not affect the effect of the drug. If there is a violation of the kidney function, a long-term osteogenide intake is prohibited. With urolithiasis, the regimen and dosage are discussed further with the doctor.
Osteogenone is taken four hours after taking iron-containing drugs and antibiotics from the tetracycline group of bisphosphonates, since the drug slows down their absorption.
Pregnancy and lactation intake
For physiological conditions, such as pregnancy and lactation, the drug is prescribed with caution to compensate for calcium deficiency, for the prevention of oedematosis under the guidance of a physician.
In case of good drug tolerance, a dose appropriate to the course of the disease can be administered.
Doctors advise
Reviews of doctors who use Osteogenon in their practice are positive.
Using in practice Osteogenon, we manage to achieve positive results. In patients after the course of therapy with this drug, the necessary level of calcium in the body is restored. There is a danger of osteoporosis. These conditions are especially frequent for girls during pregnancy and lactation, because the appearance of the baby really requires the mother to expend not only calories, but also various vitamin constituents.
It is especially necessary to monitor the level of hemoglobin and calcium in the blood in order to prevent the threat of osteoporosis.
Orthopedic Physician, Vasiliev G. N
I prescribed this medicine to many patients who needed regulation of calcium-phosphorus metabolism in bone tissues. The drug in practice has proved its effectiveness.
A few months after the start of the drug, the level of calcium gradually came back to normal and then did not decrease. But more interesting is the effect of the drug on bone tissue subjected to trauma.
The improvement seen in the examinations is already two months after the start of the course of therapy with the drug.
The drug, thanks to the presence in the composition of not only calcium and phosphorus, but also collagen, allows the body to quickly restructure the damaged parts of the bone, and conducts rapid crystallization, necessary for the construction of new bone tissue.
I estimate the effect of the drug as very effective in controlling osteoporosis and for osteogenesis.
Trauma doctor, Generalov T. A
Walking through the hospital wards
Opinion of patients taking Osteogenon.
I was prescribed a drug of 4 tablets per two doses per day for more than 5 months. At first I did not think that the effect of the drug would greatly affect my recovery, but the results of the first tests encouraged me.further, at the end of treatment, the level of calcium in the blood normalized and I was very pleased with the treatment.
There were no side effects from the drug taken, it was normally digested, there was no drowsiness, no skin reactions.
Patient of the clinic for bone diseases, Romanova E. P
I almost all the pregnancy took Osteogenon, which I appointed a doctor to replace another drug with the same effect. I practically could not take that drug, because there were problems with digestion. And I took this medication and it went well, and my calcium level returned to normal, I do not have a diagnosis of stupor.
Patient of a female consultation, Reshetova I.K.
I took the remedy for eight months as part of complex therapy and now I see a persistent positive effect, because during pregnancy and after childbirth during breastfeeding, my blood calcium levels were lowered andI felt even general weakness, malaise.
And now the level of calcium normalized, I made control tests and they are all right, as a result of this the doctor canceled my previously assigned Osteogenon. And I feel good, I can not be afraid for the appearance of osteoporosis.
Vitalina, 20
While I was taking the drug, there were no side effects, from the side of digestion everything was normal and there were no skin manifestations either in me or my baby.
The doctor initially prescribed a small dose for me, and after the birth the dosage changed, as the calcium level in my blood dropped in my tests. Now the level is stable. That is, the drug has a persistent effect, the course of treatment provides an amendment for the patient without any problems, without adverse reactions.
Angelica, 32
Tips for receiving from patients
If you are scheduled to take the drug several times a day, you can hold the reception during and after meals. It is necessary to take the tablet with a small amount of water at room temperature.
First aid for fractures
Judging by the reviews, it can be concluded that Osteogenone is very effective in fractures, the drug has a positive effect on the restructuring of tissues, it gives a positive effect in systematic long-term use, effective for single and multiple fractures.
Question of purchase
The drug is a biconvex oblong tablet with a light yellow coat. 
Tablets are produced in blisters with 10 tablets each, in a cardboard box containing 4 blisters.
Price of one bundle of Osteogenone approximately 850 rubles .
Store in a dark place at a temperature of up to 30 degrees within 4 years from the date of manufacture. The medicine is released only on prescription.
Possibility of changing the tool
There are no preparations completely analogous to Osteogenon.
The drugs of the same pharmaco-group for the effect on mineralization and bone restructuring have the same mechanism of action:
- Osteolate;
- Exjiva;
- Osteokea;
- Bivalos.
