How to correctly use the tablets from migraine Excedrine: instructions for use, reviews of doctors and the price of medicine

Excerdine is a drug that is designed to fight headaches, tooth pain, in the muscles and during menstruation.

This drug is manufactured in the Swiss company Novartis Consumer Helles SA.

It is based on : acetylsalicylic acid, paracetamol and caffeine, which are the main active substances and perfectly cope with all the symptoms.

The drug Exedrine is released in the form of tablets with a certain concentration of the active drugs in them.

More in detail we will consider the information on this preparation.

Pharmacological action

Let's study the composition of Excedrine to understand its effect on the body.

Medication Excedrine is a drug in which there are three different substances with different properties, but together they are great for fighting pains of different nature.

These substances are Acetylsalicylic Acid or Aspirin, Caffeine and Paracetamol. We will analyze their effect on the body separately.

Acetylsalicylic acid acts as a good antipyretics, has the ability to stop and prevent inflammation and reduce pain. At the cellular level, it inhibits the formation of thrombi, platelet binding and significantly improves blood circulation in the area of ​​the onset of the inflammatory process.

Caffeine has an exciting effect on the vasomotor centers and respiratory centers. It also has the ability to dilate blood vessels, reduce the ability to bind platelets.

In addition to this, Caffeine struggles with fatigue and drowsiness and increases the working capacity of the body. In combination with Aspirin, it has a positive effect on the rate of blood flow and normalizes the tone of the vessels of the brain.

As for Paracetamol , it has the ability to febrifuge and partially to inhibition of inflammatory processes. This is due to the influence of Paracetamol on the center, which controls the temperature in the hypothalamus.

How vascular dystonia manifests itself - the symptoms and signs of the disease. It is very important to identify the first signs of a stroke in women in time so that the treatment of the disease is most effective.

What happens after taking the drug

Acetylsalicylic acid in its entirety is fully integrated into the gastrointestinal tract, liver and blood, while undergoing cleavage in it. This process continues until the moment when salicylates are formed. After that newly formed substances undergo further splitting in the liver.

Caffeine , like Aspirin, is also perfectly integrated in full size, being distributed in all liquid environments of the body.

After using this substance on an empty stomach, it will be possible to detect it at the maximum concentration in the time interval 5-90 minutes after taking. Its relationship with plasma proteins is about 35%.With the help of metabolites, it is split in almost full size and, then, is excreted through the kidneys.

Easily integrated into the gastrointestinal tract, its maximum concentration can be observed after 30-120 minutes after use.

The processes of substance cleavage occur in the liver, and are excreted by the kidneys. Only 5% of the substance leaves the body in its initial state.

With the usual dose of Paracetamol , it binds to blood plasma proteins only slightly, and if this dose is increased, this interaction will increase significantly.

Indications and contraindications for use

Instructions for use on the drug Excedrine indicates such indications and contraindications to this drug.

Indications for the use of the drug

The drug Excedin is prescribed in the following situations:

• with pain syndrome;
• for headaches and migraines;
• with severe toothache;
• for pain in muscles and joints;
• for menstrual pain;
• for acute respiratory infections and flu.

Contraindications

Doctors do not recommend the use of the drug in the following cases:

• hypersensitivity to the constituents of the drug;
• problems with the gastrointestinal tract, including bleeding;
• hemophilia;
• vitamin deficiency;
• kidney problems( insufficiency);
• period of pregnancy and lactation;
• glaucoma;
• problems with sleeping, severe excitability;
• bleeding during surgery;
• age restrictions( it is forbidden to use children under 5 years old).

Drug and alcohol

Paracetamol, aspirin and alcoholic beverages receive a greater chance of developing structural and functional disorders of the liver. Caffeine in this case increases the rate of incorporation of ergotamine.

Mechanism of action

The mechanism of the action of the drug is that it acts on the sources of pain, at the same time it relieves spasm and stops the inflammatory processes, improving blood circulation in the affected area and preventing the formation of thrombi.

In doing so, it well activates the body , fighting fatigue and a desire to sleep.

Instruction for use

Let's study the instruction to Expedrin in more detail.

How to use

What you need to know:

1. The drug Excedrine should be taken orally during or after food intake.
2. On average, the allowable number of tablets per day is 3-4.The maximum dose is 6 tablets.
3. After using two tablets for headache, the result is observed after 15 minutes, and with migraines - after 30 minutes.
4. It is not recommended to take the drug without first consulting a doctor with pain more than 5 days, and more than 3 days in cases of migraine.

Forms of release

The drug Eksedrin is issued in the form of oblong tablets, covered with a white coating, marked on one side with the label "E".The package contains 16 tablets.

One tablet of the preparation Eskedrin contains 250 mg of acetylsalicylic acid, 65 mg of caffeine and 250 mg of paracetamol.

Dosage Medications

Depending on the disease, prescribe such doses:

1. To reduce or eliminate pain. Adults and children, age 12 years or older, take 2 tablets of the drug every 6 hours. It is forbidden to take more than 8 tablets per day.
2. Eksedrin tablets from migraine .Adults and children, with the age of 18 years, take 2 tablets a day. It is not recommended to exceed the permissible dose without a doctor's special prescription.

When taking Eskedrine, it is necessary to drink it with a full glass of water.

We will study in more detail the use of the drug with migraine, since the medicine for migraine Excerdin is one of the most popular remedies for this disease.

Migraine Treatment

Migraine - is a chronic illness of .Her business card is an intensified headache that extends only to one half of the head. It occurs very often among people of different ages.

Migraine attacks are observed with a frequency of 1-2 times a year, and 1-2 times a week. Women complain more often about this disease than men, although they too get this problem.

There are several theories that explain the onset of migraine. This is a poor supply of blood to the brain, a different expansion of the vessels of the brain, a change in blood pressure.

In general, the aggravation of the headache occurs after physical exertion, the use of alcoholic beverages, nervous overstrain, after stuffy rooms.

Migraine Remedy Excedrine is an effective preparation of for the treatment of migraine.

Due to the presence of acetylsalicylic acid in it and its interaction with the rest of the drug, Excedrine acts on the source of pain, while removing the spasm and stopping the inflammatory processes.

This significantly improves blood circulation in these areas. Caffeine restores working capacity to the body. Within 30-45 minutes after eating the drug, a person suffering from migraine, notice a significant improvement in his condition.

Overdose and additional indications

In cases of an overdose of the drug Eksedrin, different symptoms manifest themselves, and they are caused by the presence of different drugs in it.

In the presence of paracetamol, the following symptoms appear.

After the first 24 hours:

• skin blanching;
• nausea;
• vomiting;
• problems with glucose metabolism.

Problems with normal functioning of the kidneys occur 24 hours after an overdose.

If the dose of acetylsalicylic acid has been exaggerated, then is observed:

• nausea;
• vomiting;
• problems with eyesight.

With a strong dose increase - suffocation, respiratory paralysis, etc. In cases where the poisoning is of medium or severe severity, the person should immediately be hospitalized.

When an overdose of caffeine is observed:

• excitation;
• feeling of anxiety;
• arrhythmia;
• tachycardia;
• nausea and vomiting.

In cases of severe overdose, epileptic seizures may occur.

Side effect of

The preparation of Excedrine has a rather large list of side effects of :

• nausea, vomiting;
• disruption of the gastrointestinal tract;
• increase in blood pressure.

In case of long-term admission of , the following are observed:

• headaches, dizziness;
• problems with eyesight;
• decreased platelet capacity for binding;
• epistaxis;
• children have Reye syndrome.

Special instructions

It is not recommended to prescribe to children drugs that contain acetyl-salicylic acid because when a viral infection develops, there is a huge risk of the appearance of Reye's syndrome.

It is characterized by vomiting, which can last for a while, and enlargement of the liver in size.

In cases where the drug is taken for a long period of time, the liver should be under close medical supervision.

The preparation is characterized by the slowing down of the blood coagulation .Thus, if a person who has taken this drug plans to undergo a surgical intervention, it is necessary to warn your doctor about this.

In small doses, acitin salicylic acid reduces the excretion of uric acid.

Interaction with other drugs.

Parallel use of the drug Excedrine with other drugs leads to the appearance of various side effects. Also, as a result of this, toxins can form, which will lead to problems with the normal functioning of the liver.

Pregnancy and lactation reception

During the period of breastfeeding, this drug is also prohibited because it has the ability to excrete along with milk, thus acting in the body of a child. This can lead to bleeding in the child's body.

Admission to childhood

Children are not recommended to prescribe and take this medication because of the possibility of developing Reye's syndrome.

Reviews of patients and doctors

Reviews of doctors and patients about tablets of Excedrine are positive, especially when treating migraines.

Reviews of doctors

That's what doctors say about medication:

1. Migraine preparation Excedrine has a fairly good mechanism of action. Excellent struggles with pains that have different sources of ( Prigozhin AV).
2. Unfortunately, the drug has a fairly large list of contraindications. As a result, we are not able to prescribe this drug to all patients. And, in general, the drug proved itself well ( Samsonova RA).

Patient feedback

Patients echo to doctors:

1. I suffered from migraines for a very long time and could not find the right drug that could help me. I went to the doctor and he prescribed me to Eksedrin. In the process of eating I drank one pill, and after I ate - one more. After a short period of time, I began to feel that something was beginning to pulse in my head. And in an hour I had my headache. Very pleased with this drug ( Tatiana).
2. The drug helps, but has a significant number of contraindications. I refused ( Oleg) .

Tips for receiving from patients

Here's what advise patients:

• drink plenty of water, so the drug will quickly digest;Do not use
• without consulting a doctor.the drug has a number of contraindications;Do not use
• to treat children.

Pros and Cons of the

This is what should be considered when taking the medicine Excedrine :

• rapid elimination of pain;
• ability of the drug to fight migraine;
• not all patients of the drug can help to eliminate severe headaches with migraines;
• a big disadvantage is a huge list of contraindications and side effects that do not always end in a positive way and in some cases an overdose can lead to coma and, even, death.

Form and price

The preparation is produced in the form of tablets, covered with a white shell and having an E-mark on one side. The tablets are packed in blisters.

Price, as per medicine Excedrine 100-250 rubles , and you can buy one of the best medications for migraines from any pharmacy.

Conditions and shelf life of

The preparation should be kept in a dry place at room temperature. Shelf life is 2 years.

Leave at the pharmacy

The drug is dispensed without a prescription.

Analogues of the preparation

There is a rather large number of analogues of the preparation of Excerdin. These are:

• Geewad;
• Caffetin SK;
• Cofacil;
• Novalgin;
• Saridon and others.

Video: Excerdine - Do not Stay With Migraine One-On-One

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