1 General Information

The drug is part of the pharmacological group of medicines assigned to patients in diseases of the gastrointestinal tract. Used for gastritis with high acidity, ulcerative lesions of the duodenum and stomach.

Pharmacological action of the drug is that the active ingredient fights ulcerative lesions. It provides a reduction in stimulated and basal secretion. When gastritis provides normalization of secretion of gastric juice. The medicinal properties of the medicament do not change depending on the origin of the stimulus.

The drug is in the form of capsules. They can vary in appearance and composition. There are capsules in a package with a lid of pink color, colorless in themselves. They contain 20 ml of the active substance omeprazole. As auxiliary constituents are sucrose, mannitol, sodium lauryl sulfate, anhydrous sodium hydrogenphosphate, hypromellose, lactose, water.

Capsules called Omeza D are white in color and sold in a vial with a lid of violet color. As the main ingredients they contain omeprazole and domperidone 10 ml each. The latter component is included in the composition of the drug in order to: prevent the

• from creating a vomiting reflex in the patient;
• to improve the condition of the lower esophageal sphincter;
• to accelerate the devastation of the stomach in the event of problems with this process.

Favorable action of the medication on the body is observed already within an hour after application and lasts 24 hours.

To administer Omez intravenously, it is produced in the form of Lyophilizate, which is used to make a therapeutic solution. The bottle contains white powder, which is omeprazole in the amount of 40 mg.

Capsules and a preparation for injections can be got in drugstores only under the prescription of the doctor. It is very important to monitor the expiration date of the medicinal product and store it in a dark place inaccessible to young children. The optimum storage room temperature is 25 ° C.

Omez differently interacts with various medications. The active component of the drug increases the acidity of the stomach, and this leads to a decrease in the absorption of itraconazole, ampicillin ethers, etc. The drug helps increase the concentration or causes a decrease in the excretion of diazepam, phenytoin from the body. In this situation, you need to reduce the dose. If you take Omez in combination with antacids, then no interaction is observed.

2 Indications for use

For Omez preparation, the indications for use are as follows:

1. Peptic ulcer of the stomach or duodenum. The drug is prescribed not only to treat the disease, but also to provide preventive action in order to prevent relapses.
2. The development of ulcerative processes in the duodenum and stomach caused by the action of nonsteroidal medications that relieve inflammation.
3. Reflux esophagitis.
4. Pancreatitis.
5. Stress ulcer.
6. Erosophagitis erosive-ulcerative.
7. Zollinger-Ellison Syndrome.
8. Helicobacter pylori eradication. The drug is prescribed as a component of complex treatment.
9. NSAID-gastropathy.

In addition, the instructions for use allow the use of medication in systemic mastocytosis, gastritis. For preventive purposes, the drug is prescribed for Mendelssohn syndrome. Capsules Omez D can achieve a good result and are prescribed for therapeutic therapy of dyspepsia and gastroesophageal reflux.

3 Contraindications

Contraindications to the use of medicament:

1. Not recommended for use in women during pregnancy. How the active substance of the drug acts on the organism of the future mother and the condition of the fetus by specialists has not yet been studied.
2. You should not drink omez during breastfeeding, give medicine to children.
3. The drug is not suitable for individuals who have individual intolerance or hypersensitivity to individual constituents.
4. Patients with renal insufficiency or serious impairment of liver function should take capsules with caution and only after consultation with the attending physician.

In accordance with the instructions for the drug Omez D, in addition to the above contraindications, it can not be used if the patient has gastrointestinal bleeding or has a gastric or intestinal obstruction of a mechanical nature. It is forbidden to use the patient, if they have a perforation of the digestive organs, a tumor is diagnosed in the digestive system.

When for some reason the drug is contraindicated for use, it is worth paying attention to a number of medicines that can become an alternative to Omega. These drugs include Omeprazole, Omeprazol-Richter, Gastrozol, Ortanol, etc. However, before using alternative medications, you should consult an experienced doctor.

4 Dosage and duration of the course

The instructions for use determine the duration of treatment and dose depending on the disease. The medication can be administered in half an hour before meals or just before meals.

Do not chew capsules. They must be washed down with water.

If a patient is diagnosed with an exacerbation of duodenal ulcer, he is given a daily intake of the drug. The duration of the treatment course can last for a month. In especially severe cases, the dosage may be increased as prescribed by the doctor.

If the patient has Zollinger-Ellison syndrome, the duration of therapy depends on the change in the clinical picture of the disease. In accordance with individual characteristics, the daily dose may increase. If there is no possibility to take the drug orally, then its intravenous introduction into the body is allowed.

In cases of exacerbation of stomach ulcers or the presence of erosive-ulcerative esophagitis, erosive-ulcerative damage to the gastrointestinal tract resulting from the use of non-steroidal medicines that have an anti-inflammatory effect, the duration of drug exposure is 60 days.

With Mendelssohn syndrome, the drug is administered intravenously before bedtime, and before the operation - for 1-1,5 hours. In order to avoid relapse of such diseases as a stomach ulcer, duodenal ulcer, reflux esophagitis, doctors recommend a long course of treatment lasting about 6 months. Omeza capsules together with antibacterial drugs should be used within 7 days with the eradication of Helicobacter pylori. For intravenous administration of Omega, an infusion solution is made before the treatment procedure. It can be used within 24 hours.

5 Side effects of

Side effects of the drug is rare, but a negative effect on the patient's body is still possible. Therefore, do not allow increased doses - this will help the instructions for use, applied to the drug.

Possible abnormalities in the digestive system:

• diarrhea;
• difficulty of defecation;
• abdominal pain;
• nausea, triggering of a vomiting reflex;
• bloating.

There are cases of malfunctions in the work of taste buds in patients, sensation of dryness in the oral cavity, the appearance of stomatitis, abnormalities in the work of the liver, increased activity of its enzymes.

Negative effect on the nervous system is manifested as:

• dizziness;
• headaches;
• state of excessive excitation;
• psychoemotional disorder.

Redness and a rash accompanied by itching may appear on the patient's skin. It is not excluded the occurrence of allergic reactions to the drug, most often they are represented by urticaria. Less often there is a laryngeal edema, loss of consciousness as a result of medicamentous influence on the body, increase in body temperature, bronchospasm. There are violations in the functioning of the circulatory system, manifested extremely rarely, in the form of leukopenia, thrombocytopenia. Infections of the musculoskeletal system are infrequent.

In addition to all of the above, side effects can manifest as general weakness, impaired vision, excessive sweating, gynecomastia. With prolonged use, capsules can cause the appearance of gastric cysts of a benign reversible nature.

Before starting the use of the remedy, the doctor conducts an endoscopic examination of the digestive organs of the patient. Such measures are necessary to detect the possible development of a malignant tumor, in particular in the stomach ulcer, since the drug can hide symptoms and contribute to the formulation of an incorrect diagnosis.

Capsules can be taken while eating. In the event that there are problems with swallowing the tablet, you can open the shell and mix the contents with 1 tbsp.l.puree from apples. Keep the contents of the capsule with mashed potatoes, the mixture should be immediately swallowed and washed with plain water.

After taking the Omega tablet, there are no restrictions in the management of the vehicle or in performing any mental or physical operations requiring increased attention.

Omega is a high-quality, highly effective remedy that can combat various diseases of the stomach, intestines and gastrointestinal tract. However, due to a number of contraindications and the possible occurrence of side effects, the dosage is prescribed strictly by the order of the treating doctor.