Features of the use of ArtroCam in the treatment of joints

ArthroCam - belongs to the group of non-steroidal anti-inflammatory drugs, which not only stops inflammation, but also has analgesic and antipyretic effects.

The active substance of the drug is ibuprofen.

Produced in the form of tablets of 400 mg, film-coated.

Pharmacodynamics and pharmacokinetics of the drug

When ingested, COX - the main enzyme, which is involved in the exchange of acharic acid, and it in turn is necessaryI production of prostaglandins, which play an important role of the development of inflammation, pain and fever. In addition, ibuprofen prevents the adhesion of platelets.

Active substance used in external medicinal forms, eliminates inflammation morning stiffness, increases the amplitude of motion of affected joints, has analgesic effect.

When taken orally, ibuprofen is almost completely absorbed from the digestive tract. Simultaneous food intake reduces the rate of absorption of the active substance. Passing through the hepatic barrier, 90% of ibuprofen undergoes metabolism. The elimination half-life lasts 2-3 hours.

20% of the taken substance is excreted as metabolites with bile, the remaining 80% through the kidneys, of which 10% unchanged, the rest in the form of metabolic products.

Scope

The drug ArthroCam is prescribed for the treatment of rheumatic pathology, as well as as an antipyretic, anti-inflammatory, analgesic.

It is included in the treatment of such diseases of the musculoskeletal system:

• arthropathy of any etiology;
• bursitis;
• deforming arthrosis;
• ankylosing spondylitis;
• tendonitis;
• radiculopathy;
• muscle pain;
• trauma of the musculoskeletal system;
• neuralgia.

In addition, ArthroCam tablets are prescribed as:

• analgesic agent for headache, dental and menstrual pain, ENT diseases with a pronounced pain syndrome;
• antipyretics for colds and other conditions accompanied by high body temperature.

Restrictions on the use of the drug

Absolute contraindication to prescription of the drug are the following conditions:

• hypersensitivity to the components of tablets;
• intolerance to aspirin and other NSAIDs;
• bleeding disorders, such as thrombocytopenia, hemophilia, hemorrhagic diathesis;
• exacerbation of diseases of the digestive tract, such as stomach ulcer and duodenal ulcer, granulomatous enteritis, ulcerative colitis;
• internal bleeding;
• hyperkalemia;
• severe liver and kidney pathology;
• intolerance to monosaccharides;
• aortocoronary bypass in history;
• age is younger than 12 years;
• pregnancy;
• Breastfeeding.

The relative contraindication to prescription of the drug are:

• old age;
• increased pressure;
• blood pathologies of unclear genesis, including reduced hemoglobin and leukocytes;
• alcohol and nicotine dependence;
• hyperlipidemia;
• disease of peripheral blood vessels and heart, including heart failure, ischemic heart disease;
• diabetes mellitus;
• cerebrovascular pathologies;
• erosive and ulcerative gastrointestinal diseases in history;
• severe physical illness;
• condition after surgery.

Instruction: dosage and duration of therapy

Dosage is selected individually, depending on the clinical picture.

Usually patients over 12 years of age are recommended to take 200 mg of the drug up to 4 times a day. To improve the well-being of the patient, it is allowed to take the drug 400 mg 3 times a day.

The maximum single dose should not exceed 800 mg, daily - 1200 mg.

If after 3 days of taking the drug you do not see any improvement, you should immediately contact the doctor to clarify the diagnosis.

Pharmaceutical compatibility

In parallel application of the means ArthroKam, it:

1. Weaken the therapeutic effect of antihypertensive drugs ( ACE inhibitors, β-adrenoblockers), diuretics( laseks, hypothiazide).
2. At a one-time admission with anticoagulants , oral hypoglycemic agents and derivatives of sulfonylurea and hydantoin, there is a possibility of enhancing their effect.
3. In parallel with the glucocorticosteroids , the likelihood of developing adverse reactions from the digestive system increases.
4. When administered in combination with with amlodipine and captopril , there is a possibility of a slight decrease in the antihypertensive effect;with Aspirin - the level of ibuprofen in the systemic blood flow decreases;with Baclofen or Methotrexate - the toxic effect of the latter is enhanced.
5. When combined with Warfarin , the probability of increased bleeding time, the appearance of microhematuria, hemorrhages increases;with Kolestyramin there is a moderately pronounced decrease in absorption of ibuprofen.
6. At parallel reception with lithium carbonate the level of lithium in a blood plasma increases.
7. In a single-stage application with magnesium hydroxide , the absorption of ibuprofen increases.
8. Caffeine enhances the analgesic effect.

Special instructions

The drug is contraindicated in severe kidney and liver pathologies. With mild and moderate disease of these organs, medication is permitted, but the patient must be under constant medical supervision. During treatment, it is necessary to regularly check the work of the kidneys and liver, to take a detailed blood test.

You should not take the drug in the last trimester of pregnancy. In the first and second trimesters of pregnancy, it is permitted to prescribe a medicinal product if the expected benefit for a woman exceeds the probable harm to the child. Take the drug at 200 mg to 4 times a day. The maximum daily dose should not exceed 0.8 g.

The active substance in insignificant amounts is released through the mammary glands. Prescribe the drug during lactation with pain and high temperature can be 200 mg 3-4 times a day.

In case of prolonged treatment or taking in a dosage of more than 0.8 g / day, it is worthwhile to transfer the child to the mixture. Children under the age of 12 years are not prescribed the drug ArthroCam, they are discharged over the age of 12 years as usual.

Do not take medicine for women planning to conceive, since the active substance adversely affects women's fertility.

Do not consume alcohol-containing beverages during treatment, and you must be extra careful when driving.
If you need to test 17-ketosteroids, the ArthroCam tablets should be discarded 2 days before the test.

Adverse reactions

The following side effects may occur on the background of the drug administration:

• Digestive organs may experience nausea, epigastric pain, vomiting, loose stools, anorexia, erosive ulcer pathologies, bleeding, liver disorders;
• central and peripheral nervous system possible headache, dizziness, sleeping problems, agitation, blurred vision;
• of the hematopoiesis of may be a drop in platelet, leukocyte and hemoglobin levels;
• of the genitourinary organs of , there is a risk of kidney impairment;
• cardiovascular system there is a chance of hypertension, cardiac insufficiency, increased heart rate;
• respiratory organs may appear shortness of breath and bronchospasm;
• hearing organs have a risk of hearing loss and tinnitus;
• laboratory indicators possible reduction of glucose and hemoglobin in the blood, decreased creatinine clearance, prolonged bleeding time, increased activity of hepatic enzymes, increased serum creatinine.

In addition, it is possible to develop allergies in the form of skin rash, angioedema, aseptic meningitis( usually in patients with autoimmune diseases), bronchospasm.

From the practice of using

The doctor and patient who have tried ArthroKam in practice.

At present, you can buy such analogs of the preparation ArthroKam as MIG, Nurofen, Ibuklin, Ibuprofen.

Store the drug at a maximum of 30 degrees in a place protected from light and moisture. The drug belongs to the list B.