In many lists of medical appointments for joint pain, arthrosis, arthritis, rheumatism and other diseases of the ODA, one can find the drug Dicloberte.
Based on the composition of the drug diclofenac sodium, which belongs to non-steroidal anti-inflammatory substances, it reduces pain and relieves inflammation.
Content of the article
- Form release and composition of the drug
- Pharmacological profile
- Use in orthopedics
- Contraindications to prescribing
- Scheme of taking and dosage
- Overdose cases
- Side effects
- Drug interaction
- Opinion review
- Price
Forms and composition of the drug
Dependingfrom the form of release the preparation differs on structure, but the basic treating ingredient is identical everywhere - diclofenac sodium.
Dicloberl is available in the following forms:
- injections : water for injection, diclofenac sodium, sodium hydroxide, propylene glycol, mannitol, acetylcysteine, benzyl alcohol;
- tablets : corn starch, diclofenac sodium, sodium salt of carboxymethyl starch, methacrylic acid, lactose monohydrate, povidone K30, magnesium stearate, talc;
- capsules Diclobber retard: cornstarch, sodium diclofenac, shellac, oidragit RL 12.5, titanium dioxide, white gelatin, sucrose, talc;
- candles : ethyl alcohol 96%, solid fat, corn starch, diclofenac sodium, propylgalate.
Pharmacological profile
Formula diclofenac sodium
The active ingredient Dicloberla has an anti-inflammatory effect. Additional effects: anesthesia, heat removal, due to which it is an effective remedy for relief of conditions in rheumatic and other diseases of the musculoskeletal system.
The basis of the healing effect is suppression of cyclooxygenase activity, from which prostaglandins are synthesized. Due to this, the drug reduces inflammation and has an anesthetic effect.
Food intake and metabolic disintegration of Dicloberla are not affected by food intake. In any case, the drug is effectively absorbed and withdrawn from the body in a timely manner. So if you adhere to the correct dosage and regimen, then the body does not accumulate the drug.
After intramuscular injection in the blood, the maximum concentration is achieved in just 20 minutes. And when taking tablets or capsules an average of 2-3 hours( but sometimes from 1 to 16 hours).The maximum concentration with the use of the suppository occurs in half an hour.
About 30% of the active substance is metabolized. Some metabolites are excreted through the intestines, with bile, but mostly excreted by the kidneys. Half-life takes about 2 hours
Uses in orthopedics
The main application of Dicloberla is all sorts of rheumatic joint diseases - rheumatoid arthritis, rheumatism or 
osteoarthritis.
Other reasons for prescribing the drug:
- gout;
- Bechterew's disease;
- dystrophic joint disease;
- is prescribed for neuralgia and myalgia( inflammation of nerves and muscles, respectively);
- for pain relief and inflammation reduction in the postoperative period( except for heart surgery);
- in gynecology is used to relieve primary dysmenorrhea;
Contraindications to prescription of
Do not prescribe medication if any:
- hypersensitivity to any of the components of the drug;
- any abnormality of the gastrointestinal tract( ulcers, perforations, bleeding, etc.) in the anamnesis or current condition, there is a high risk of bleeding of any etiology;
- renal, hepatic or congestive heart failure;
- heart disease( ischemia, angina pectoris, tachycardia, a previous myocardial infarction), arterial disease;
- cerebrovascular diseases, strokes, ischemic attacks;
- the age of the patient is less than 15 years.
Dicloberla 50 may be used in the first and second trimester, but in the lowest possible doses. In the 3rd trimester, the use of the drug is strictly prohibited. Although some doctors completely prohibit the use of the drug throughout pregnancy and lactation.
Dose and dosage regimen
The exact dosage and the regimen can only be prescribed by a doctor, but if you follow the official instructions for use, then Dicloberl should be taken as follows.
The initial dose is not more than 150 mg per day. With minor pain, 75 mg may be sufficient. Take the medicine you need while eating, do not chew. Wash with a few sips of water.
The daily dose is divided into 2-3 doses. At night it is recommended to use Dicloberl candles.
Dicloberte Retard because of the greater dosage of diclofenac is recommended no more than once a day!
No injections for more than 2 consecutive days. If you need a longer course, then injections are replaced with tablets or capsules. Dose - 1 injection a day.
Cases of overdose
In case of an overdose, there may be headache, nausea and / or vomiting, stomach pain( sometimes until bleeding).
Possible as asthenic manifestations( weakness, drowsiness, dizziness or tinnitus), and overexcitement. In case of severe intoxication, coma or acute renal failure may occur.
Treatment in this case is symptomatic. If less than an hour has passed since the reception, you need to rinse the stomach and take activated charcoal.
With prolonged or prolonged convulsions, a diazepam prick is needed intravenously. But in case of the slightest suspicion of serious violations, it is urgent to call a doctor.
Side effects of
With the high efficiency of Diclobber, it has a very wide list of side effects. That is why it is not recommended to use long courses.
The drug has a negative effect on all body systems: 
- is the most affected gastrointestinal tract. When poisoning, negative reactions from nausea to ulcers, perforations and bleeding are possible.
- The second target is the cardiovascular system .When using the drug, the risk of bleeding increases. As already mentioned gastrointestinal, and nasal and subcutaneous.
- On the side of the nervous system , it is possible to develop a stroke and a heart attack.
In case of kidney or liver disease, as well as in case of treatment of elderly people, therapy should be under the supervision of a doctor, at least within an hour after using the drug.
Medication affects concentration of attention and coordination of movements. Therefore, it is recommended to refrain from driving and using complex mechanisms during the period of use.
Drug Interaction
When receiving Diclobber:
- because of a violation of pharmacokinetics do not recommend the use of preparations containing lithium : Digoxin, Methotrexate,
Cyclosporin, Tacrolimus, Phenytoin, Probenecid, Mifepristone, CYP2C9 inhibitors, Cholestipol and Cholestyramine; - reduces the effect of diuretics and antihypertensive agents , so joint use is only possible under the supervision of a physician, especially in the case of elderly patients;
- when taking medications that provoke hyperkalemia requires a more frequent examination of the patient's condition due to elevated levels of potassium in the blood;
- anticoagulants, other NSAIDs and antithrombotic agents when combined with diclofenac drugs increase the risk of bleeding;
- when taking antidiabetic medication requires more careful blood sugar control;
- antibacterial quinolones when taken together with the drug may cause seizures;
- cardiac glycosides in conjunction with diclofenac can provoke heart failure.
Review of opinions
Before applying Dicloberla it will be extremely useful to study the reviews of doctors and those people who have experienced its effect on themselves.
Long-term courses of non-steroidal anti-inflammatory joints with joint pain are possible only in extreme cases, too many side effects. And for short the Diclobert retard works best, because it has minimal impact on mucous housing and communal services.
General practitioner, 2 years of experience
A good drug, very helpful when you need to urgently remove the pain syndrome. But I try to assign it only to young or even relatively healthy people. If a person has ever gone to a gastroenterologist with problems, I'll think three times if he needs it. Most often I assign candles if pains prevent me from sleeping.
Therapist
In our family, Dicloberte has already experienced everything because everyone has some problems with joints. My husband and I were not lucky on the back, it hurts often.
My mother is suffering from rheumatoid arthritis. And my father started to suffer as a gout in his youth. And if it hurts so much that there is nothing to be done, then Dicloberl is saved.50 tablets cost about 400 rubles - not so expensive, and the pain is well removed.
But only with a doctor should be consulted, and then pobochek what list!
Karina Petrovna
I read a lot of reviews about Diclobberl and studied the list of contraindications - it was even scary to take. But when the back became very unbearable, she decided. She torments me from her youth, but here in general, I did not even want to breathe!
Then I took out the pills from the first aid kit. I had a doctor appointed him for a long time with a myome, but then I did not take the drug, I did not want side effects to get more than good. And then - directly salvation. Half an hour later I was able to breathe and move. And even before the doctor stumbled.
But he said that I was not particularly addicted to tablets, which all the same greatly affect the body.
Marina
Price
Price Dicloberla depends on the form of release and the amount of medicine in the package:
- injections sell in boxes of 5 ampoules, they contain 3 ml of the solution, the price is approximately 430 rubles;
- tablets with a soluble coating, in blisters, 50 or 100 pieces, the price is from 395 rubles;
- capsules in a dosage of 100 mg, are contained in blisters in the amount of 50. 20 or 10 capsules, the price is from 450 rubles;
- candles are sold in packages of 5 or 10 pieces, the price is from 475 rubles.
Store the drug for 3 years in a dark place with a temperature of up to 25 degrees and away from children.
Diclobarle analogues are almost all NSAIDs based on diclofenac:
- Diclofenac;
- Neurodictivitis;
- Diklogen and others.
