The disease that many suffer - osteoarthritis.
For its treatment in Germany, Synvisc was developed. This substance is a chondroprotector.
This drug can replace or replace the synovial fluid located inside the joint.
Independently treated with such a drug will not work, as this is a fluid that is injected into the joint by injection, and only a doctor can do it.
Table of contents
- Pharmacokinetics of the drug
- Mechanism of action
- Purpose of the drug
- Limitations and contraindications for use
- Instruction for use
- Dosage adjustment
- Overdose and additional indications
- The word to physicians and patients
- Patients advise
- Advantages and disadvantages
- Purchase and storage
- Equivalent replacement
Pharmacokinetics of the drug
Synvisc contains gilanes. These are hyaluronic acid derivatives. The medicine is a hydrated gel.
This drug can replace and replenish intra-articular fluid in any pathology of the joints.
The product includes:
- gilan - active substance 8 mg in 1 ml;
- sodium chloride - 8.5 mg - supplement.in-in;
- sodium hydrophosphate - 0.16 mg - supplemented.in-in;
- sodium dihydrogen phosphate - 0, 04 mg - help.in-in;
- water for injection - 1 ml.
Sometimes the drug is also called a synovial fluid prosthesis.
Mechanism of action
Recovery of viscosity helps to restore the physiological properties of the joints affected by arthritis. This helps reduce pain and discomfort.
Allows you to increase the amplitude of motion and protect cartilage cells from damage to chemical and mechanical factors.
The purpose of using
The main purpose of using Synvisc is to help joints with osteoarthritis and osteoarthritis of the knee, hip, ankle, ankle joints.
Limitations and contraindications for use
Contraindications:
- congestion of lymph or venous blood supply to the affected side;
- is an inflammation or infection in the site of a future injection;
- can not be used for intravascular injection;
- can not be injected into the tissue and capsule of the joint;
- should not be administered after disinfection of the skin with special preparations, since hyaluronan may precipitate;
- is not used in pregnant women, children and adolescents under the age of 18;
- should never be administered to patients who are allergic to chicken protein;
- is not administered with a strong intra-articular effusion.
After administering the drug, a gentle regimen without motor activity is required for several days.
Instruction for use
The drug is injected into the joint at room temperature.
For better digestibility, it is better to pump synovial fluid, exudate. We necessarily select the necessary needle for each joint.
The drug is administered only in one joint. Synvisc is introduced only into the intra-articular cavity. For proper administration of the drug in the hip or shoulder joint, it is possible to make an X-ray.
Selection of dosage
For the knee, 3 injections are necessary with an interval of 1 week between them. The maximum dosage will be 6 injections within 6 months.
In case of hip, shoulder and ankle osteoarthritis, 1 injection is recommended. For greater effect, you can repeat it in 1-3 months. Synvisc does not have an effect on the body as a whole.
He works only on restoring the affected joint.
Overdose and additional indications
No cases of overdose have been identified. It is recommended to use the number of injections in each case, which is indicated above.
When the drug is administered, patients notice swelling, short-term pain, exudate inside the joint. Sometimes due to a long delay exudate there is a long pain syndrome.
Also can be:
- significant pain syndrome;
- dizziness and headache;
- rash;
- urticaria;
- itching and nausea;
- besides this there is a possibility of muscle cramps and paresthesias;
- peripheral edema at the injection site;
- redness of the skin;
- weakness and difficulty breathing;
- as a probability of anaphylactic shock.
Alcohol should in any case be excluded from joint disease. An exception is a glass of wine.
If the liver and kidney function is impaired, the drug can be used, since it does not affect the body, it affects only the affected joint.
The drug is contraindicated in patients who are allergic to sodium hyaluronate.
The drug is contraindicated in pregnancy and lactation. Children can not be administered, it is used in adults over 18 years of age.
A word to doctors and patients
Reviews of doctors and patients who were injected with Synvisc.
This drug is successfully used for problems with joints. Despite the fact that the drug is expensive, many patients decide on injections and do not regret it. Especially noticeable effect is present in patients with knee osteoarthritis.
Oksana Ivanovna, traumatologist
Colleagues often prescribe Synvisk and other chondroprotectors. Since they have been clinically tested, these medications are not only safe, but also useful, since the real result is visible. Of course, a lot depends on the correctness of the injection.
Viktor Petrovich, Surgeon
The knee was aching, maybe because of weight or trauma affected. I tried a lot of tablets, saw and expensive drugs. The doctor advised to make an injection of Synvisc. I decided, because otherwise I could not walk.
At first it hurt, then the joint was developed. A total of 3 injections, and now I will soon go on a new course, said a year later to repeat.
Klavdiya Grigoryevna 67
I injured my ankle, I limped for a long time, my joint prevented me from working. I already thought everything, I will become an invalid. The doctor advised the preparation Synvisc, in the form of an injection. So far, everything is fine, there are no complications.
Oleg 37
Patients advise
Tips for receiving from patients:
- very much depends on the skillful hands of the surgeon, since the injection into the joint is no laughing matter;
- is not worth loading a patient with joint work, take a vacation to recover;
- quality of the injection and the result depends on the observance of the rules of asepsis and antiseptics, see that the injection is done with gloves, and the doctor should open the package in the patient;
- if there is even the slightest doubt or contraindication, it is better to choose another form of treatment.
Advantages and disadvantages of
Each drug has its pros and cons, this is not an exception.
From the pluses it is possible to note:
- a successful composition of the remedy, which helps to feed the cartilage;
- ready syringe, which no longer needs to be typed;
- the opportunity to do without an operation.
Cons:
- requires a qualified specialist for injection;
- is contraindicated, especially dangerous allergic manifestations.
Purchase and storage
Price Synvisc:
- syringes of 2 ml three pieces per pack, the price of 7110 rubles;
- syringe to 6 ml 1 per pack, the price is 19710 rubles.
Store at temperatures between 2 and 30 degrees. Do not freeze. Available without a prescription.
Equivalent replacement of
Analogs of medicine Synvisc: 
- Fermatron;
- Hyastat;
- Synocrome;
- GO-ON;
- : Ostanenyl;
- Duerolan.
For example, Hyastat is cheaper than Synvisc. One syringe costs 2800 rubles. However, each decides for himself, use analogues or choose the remedy that the doctor appointed.
To improve the lubrication of the cartilage of the joint, the synovial fluid, which is the drug, is necessary. Therefore, with obvious pathology, one should not doubt.
Of course, there is a risk of allergy and other side effects, as the drug quickly gets into the inside, but these reactions can be from other drugs. If there is an alternative between the operation and the injection, it is better to choose the lesser of the evils.
One of the most important decisions is the choice of a specialist. Make sure that he did such manipulations and more than once to avoid possible complications. It is best to apply for injections not in a polyclinic, but in a hospital or a paid clinic, where they guarantee the quality of treatment.
