Sibazon is a modern and effective anxiolytic drug. The drug belongs to a group of tranquilizers. Has an anticonvulsant, sleeping and relaxing effect, participates in the relaxation of tense muscles.
The drug is often taken as an auxiliary, as it enhances the action of neuroleptic, anticonvulsants, and hypnotics.
Do not use with alcoholic beverages, because their destructive effect on the body after taking Sibazon also increases. The drug reduces the heart rate and the secretion of gastric juice.
Contents
- Pharmaceuticals and Composition
- Scope
- Do no harm
- How to take safely and effectively
- Overdose cases are not uncommon
- Possible side effects
- Special instructions
- From information from doctors
- Patient opinion
- Is it possible to buy?
Pharmaceuticals and Composition
Active substance - diazepam, contained in the drug, reduces the excitability of the subcortical areas of the brain responsible for the emotional state. It eliminates feelings of fear, tension and anxiety. Has anticonvulsant and antiarrhythmic property, reduces muscle tone.
Sibazon acts as a sedative, anticonvulsant and anxiolytic agent. Has miorelaksiruyuschee effect by inhibiting spinal reflexes.
This is a synthetic product. Produced in the form of tablets and solution. Tablets for adults in the composition have 0.005 g of active substance, and for children tablets with 0.002 g of active ingredient, coated with a coating, are produced.
Sibazone solution is issued in ampoules of 2 ml and has 0.5% of active substance.
The active ingredient is diazepam and auxiliary components: milk sugar, starch, povidone and calcium stearate. 
The drug is rapidly absorbed, its maximum concentration in the plasma occurs after 1.5 hours. With plasma proteins bind up to 98%.Penetrates through the placenta, cerebrospinal fluid, is present in breast milk. Metabolized in the liver and excreted through the kidneys up to 70%.
The drug enhances the inhibitory effect of gamma-aminosic acid in the central nervous system. Has miorelaksiruyuschee effect due to inhibition of spinal reflexes. May cause anticholinergic effect.
Scope of use
Indications for use of Sibazone are as follows:
- anxiety, insomnia;
- withdrawal syndrome( anxiety, tremor);
- spasm of skeletal muscle when injured;
- spastic conditions resulting from exposure to the brain or spinal cord;
- polyarthritis, arthritis, bursitis, myositis;
- arthrosis with skeletal muscle tension;
- neuroses, borderline states with a sense of fear, anxiety and anxiety;
- epilepsy;
- premature birth or placental abruption, relief of labor.
It is also used in combined anesthesia as one of the components used.
Do not harm
Do not use medication if there are the following factors:
- intolerance to diazepam;
- when in a coma or shock state;
- for acute intoxication with alcohol with a threat to the functioning of body systems;
- with myasthenia gravis;
- in case of poisoning with drugs depressing the central nervous system;
- with angle-closure glaucoma;
- in the presence of severe lung disease and respiratory failure.
Do not give the drug to young children under 30 days of age.
How to take safely and effectively
The dosage of Sibazone depends on the complexity and nature of the disease: 
- for the treatment of adult patients in psychiatry and neurology, a drug is recommended for 5-10 mg three times a day;
- as an anxiolytic agent - 2.5-10 mg two or four times a day;
- arterial hypertension and angina, as well as diseases and problems in obstetrics and gynecology - 2-5 mg three times a day;
- for children with a psychosomatic disorder or spastic condition in the norm of 1 mg, gradually adding up to the optimal;
- for children from 6 months is enough 1-2.5 mg.
Cases of overdose are not uncommon
An overdose of the drug leads to the following symptoms:
- drowsiness;
- confusion;
- reduced reflexes;
- tremor;
- weakness;
- shortness of breath;
- faint heartbeat.
Patient needs to rinse the stomach and prescribe a forced diuresis. Also conduct symptomatic therapy in a hospital. For the manifestation of symptoms, it is sufficient to take a double dose of the drug.
Possible side effects of
Most of the "side effects" are observed from the nervous system:
- weakness;
- dizziness;
- sleepiness.
- confusion;
- depression;
- tremor;
- headache;
- vision impairment;
- alarm;
- insomnia;
- hallucinations;
- excitement.
From the digestive tract:
- nausea;
- constipation;
- dry mouth;
- drooling.
From other systems:
- urinary incontinence;
- lowering of blood pressure;
- breathing disorder;
- skin rash;
- decreased libido.
Special instructions
The agent is prescribed with extreme caution if a person has severe cardiac and respiratory insufficiency, organic changes in the brain.
If treatment has been long, it is necessary to gradually reduce its dose, rather than stop taking it sharply, otherwise there may be convulsions, tremors, agitation.
The drug reduces the speed of psychomotor reaction, so you can not engage in hazardous activities after treatment with Sibazon. It can not be injected into the artery and mixed in one syringe with other means, it will precipitate.
It is worth knowing the following facts about Sibazon therapy:
- Interaction with alcohol .You can not drink alcohol during the treatment, even low-alcohol drinks. The drug intensifies the action of ethanol, which leads to confusion and even its loss.
- If the kidneys and liver work .The drug should be taken very carefully in the presence of acute liver or kidney pathologies, as well as with severe hepatic insufficiency.
- Interaction with other medicines .The drug can enhance the work of certain drugs: analgesics, neuroleptics, various psychostimulants, hypnotics. The positive effect of the drug increases the effect of
fluoxetine, cimetidine, fluvoxamine and ketoconazole due to normal absorption, distribution and excretion from the body. - In pregnancy and lactation, .The drug should not be administered to pregnant women in the first trimester, as it adversely affects the fetal CNS.Sibazon is used to improve labor during delivery until the time and after detachment of the placenta. When breastfeeding the drug is also contraindicated, because it is excreted with milk, which can harm the baby: reduce the sucking reflex or stimulate the occurrence of respiratory failure.
- Treatment of children .The drug for intravenous or intramuscular administration can be administered to children with 30 days of life, and pills only at 6 months of age. The newborn drug is not prescribed because they do not have an enzyme system that takes part in the metabolism of diazepam.
From information from
doctors Comments of doctors who apply Sibazon in their practical activities.
Sibazon has been known for a long time and has been successfully applied. Especially effective as an ambulance for convulsions of unknown cause, for stopping seizures with epilepsy. The drug removes increased excitement and reduces cravings for alcohol. Take should only be prescribed by the doctor and in the recommended dose.
Suvorova NK, Moscow
I'm a narcologist physician. When Sibazon did not apply to narcotic drugs, it worked much easier. He well removes the symptoms of alcohol dependence, than the drug that we are working with now. Some people began to use it for personal pleasure and became dependent on it. It leads to the degradation of the personality, the destruction of a person physically and mentally. Therefore, the drug should be prescribed according to the indications and only by the doctor.
Anton Pavlovich, Ekaterinburg
Patients' opinion
Patients have their own vision.
My son is 9 months old, tortured with cramps. The doctor ordered Sibazon, we have been drinking for a week. The first two days only slept, was like a rag, and then the cramps returned, but not so often and more gently.
Marina, Tver
I do not like the fact that the drug hits the breath - breathing becomes superficial, and the panic only intensifies. The doctor prescribed a pill under the tongue for a quick effect of 10 mg, I drink 5 mg each and then this is for me a shock dose. I'm waiting for a wild panic and experimenting.
Olga, Moscow
Patients treated with the drug are advised to switch to Sibazon only as a last resort. With prolonged use, the drug causes addiction and dependence as a drug. He acts in different ways: he calms one, and the other, on the contrary, excites. It is necessary to take it very carefully, and with the appearance of unpleasant symptoms immediately stop treatment.
According to the patients' reviews, the drug also acts as a good sleeping pill, relieves the feeling of anxiety and helps with the withdrawal of the convulsive syndrome. The minus one of this remedy is drowsiness.
Is it possible to buy?
Tablets of 5 mg No. 20 - about 20 rubles, and a solution in ampoules - about 70 rubles. Buy Sibazon in the pharmacy network is quite difficult, from 2013 it is used only in a hospital.
The drug is on the list of potent drugs. Store in a dark place at a temperature of no higher than 30 degrees, so that it is not accessible to children. Shelf life - no more than 3 years for tablets and 2 years for ampoules. 
Buy Sibazon in Russia without prescriptions is impossible, and with it is quite difficult, but its analogs are available:
- Apaurin;
- Valium;
- Diazepam;
- Relanium;
- Rolandorm;
- Seduxen.
