Tagist drug - instructions for use, recommended analogues and reviews of doctors

Tagista( Tagista) is a drug used by for diseases of the vestibular apparatus .

Tablets are cylindrical, flat, with a facet and a risk, almost white or whitish-cream color.

The active principle component is betahistine dihydrochloride.

Substances auxiliary - microcrystalline cellulose, povidone, potato starch, aerosil, talc, magnesium stearate.

The registration number of the drug LSR-006480 / 08-130808.The non-proprietary international name is betagistin. MAKIZ-PHARMA, Moscow, Automobile fare 6. Index - 109029

pharmacological action of the drug

main active ingredient Tagista the drug has an effect similar to histamine, improving circulation processes in the cochlea, labyrinth by a certain effect on the receptor component of the vascular construction of the inner ear, the nucleus of the vestibular apparatuscentral nervous system.

This medication reduces the amount and intensity of dizziness, tinnitus decreases or disappears, resulting in hearing loss can be normalized.

Pharmacetics

Tagysta has a low bond with plasma proteins, absorption occurs rapidly, plasma concentrations peak after 3-4 hours.

The drug is excreted by the kidneys almost completely within a day. The elimination half-life is about three or four hours.

Indications

Instructions for use to the drug Tagista indicate that appointed him at:

1. Prevention and treatment of vertigo of various etiology( vertigo that occur under nervous system diseases - migraine pain, epilepsy, multiple sclerosis, Parkinson's disease, vestibular neuronitis- often occurs after SARS, benign paroxysmal positional vertigo).
2. Syndromes including pain in the head, noise effects in the ears, dizziness, nausea and vomiting, progressive hearing loss.
3. Ménière's disease( the causes of the onset are not sufficiently studied, most often suggest the emergence due to the effects of an ear injury or head, vascular disease, due to infectious diseases or inflammatory diseases of the inner ear).

Contraindications

same instructions for use on tablets Tagista indicate some contraindications:

• women during pregnancy, breast-feeding( no reliable data on the impact);
• with hypersensitivity to any of the components Tagisty;
• to 18 years of age due to lack of data.

For some diseases, the drug is prescribed with greater caution under the constant supervision of the doctor, namely, gastric and intestinal ulcers, asthma, pheochromocytoma.

Mechanism of action

The therapeutic effect of the medicinal drug Tagest( synthetic analog of histamine) is mainly associated with the effect on histamine receptors.

The drug has three levels of exposure to - to the cochlear blood stream, to the central vestibular apparatus and to the peripheral vestibular apparatus.

Betagistin dihydrochloride has an effect on H1-( increases the response) and H3 receptors( powerfully blocks) the vestibular nuclei of the central nervous system and inner ear, which leads to an increase in blood flow in the arteries, called basilar cells.

Also results in normal pressure in the fluid located in the membranous part of the labyrinth of the ear and in the cochlea and greatly improves the microcirculation processes in the capillaries and their permeability;Conductivity processes in the neurons of the vestibular nuclei are normalized.

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Instruction for use

The drug is available in tablets of 8 mg, 16 mg or 24 mg of the main active substance both in a cellular package( in an amount of 10 to 30 pieces) and in a plastic container( 100, 50 or 30 pieces.).

The drug is taken with food, washed down with some water, in dosage:

• 8 mg - one or two tables.three times a day;
• 16 mg - half or 1 tab.three times a day;
• 24 mg - one tablet.twice a day.

The time-limit for cessation of treatment is usually established by a medical specialist who has studied the individual physiological characteristics of the patient, from the stage of the disease, the concomitant diseases and complications caused by them.

Overdose and additional indications

Prolonged clinical trials have shown that when taking Tagyst in an amount of a daily dose( up to 16-48 mg in two or four doses) prescribed by a doctor, there is no overdose.

But you can always exceed the required dose of three times.

In case of unintentional overdose:

• nausea;
• vomiting;
• sometimes convulsive reactions.

First aid in overdose medications shows gastric and intestinal cleaning by rinsing and taking sorbents( for example - activated charcoal).

Side effects of

All medications have some side effects. Usually this happens with long-term drug intake or when taken in the largest-to-large dose.

When taking Tagist are possible:

• disorders of the intestines and stomach;
• headache;
• skin may respond with rash, itching or redness;
• less often - edema by the type of Quincke, tachycardia.

Special instructions

Reviews of doctors and patients to Tagist tablets indicate that that:

1. It is not recommended to take alcohol and this medication. Treatment may not have an effect, and the consequences will be negative.
2. The drug is not inherent in suppression of consciousness, so it does not interfere with the kinds of work for which a quick reaction is required. Also does not interfere with the driving of the car.
3. In diseases related to the inadequate or abnormal activity of the kidneys and liver, the administration of the drug is strictly according to the prescription and recommendations of the attending physician.

Interrelation with other drugs

Clinical trials of incompatibility or interaction with other drugs have not been identified.

However, in case of taking two or more drugs at the same time, it is necessary to notify the attending physician about this. The effects of Tagist's preparation are weakened by antihistamine drugs, hydroxysin.

Reviews about the

drug Let's consider specific responses of doctors and patients

Reviews physicians:

1. Kutasova M.K., neurologist 19.05.14 - Tagista is an effective drug that is safe and has the same healing properties as its more expensive analogues. I have offered it to my patients for a long time, I did not censure them. Reception of the drug is quite time-consuming, but the facilitating effect comes fairly quickly. There were no complaints of side effects.
2. Solovyeva TS, senior pharmacist , 21.11.13 - Tagist's drug is in constant demand. Admission is not associated with any difficulties( other than duration), it is easily tolerated by the body and, according to buyers' reviews, the negative effect on the body is minimal, most likely because of the private deviations in the health of some patients.

Reviews of patients

1. Andrew, 27.07.17 - After the accident and the courses of treatment, there was observed dizziness, frequent tinnitus. Has addressed to the doctor. After the passed examinations to me have written out preparation Taghista, I drink about one month - the state of health was normalized, the noise in ears has left and dizzinesses almost have stopped. You need to drink courses and for a long time.
2. Julia, 11.06.14 - Mom some time ago began to pay attention to the appearance of unpleasant sounds in the ears and dizziness. Hearing became worse than the before. She works as a teacher of elementary school in the school, her problems began to lead to unfitness. Cured she tablets tagists. Saw about three weeks, the symptoms are gone, the doctor praised the result and ordered to drink at least two months.
3. Sergey, 08.01.14 - The father takes Tagistu, he is already 72, dizziness has occurred, hearing has worsened, sometimes the crackling in his ears stops. It was difficult for him to get out of bed, swaying sometimes. The examination was carried out according to the doctor's prescription and began to take the drug. We have been drinking for about two months, the condition has improved significantly, and there have been no side effects to date.

Tips for receiving from patients

The main thing is to take :

• take the drug for a long time, so you need to be patient and do not miss taking pills - keep a diary of taking the medicine;
• from prolonged use of the drug there are disorders of the intestine - consult a doctor how to avoid it or how to protect the intestines.

Pros and Cons, Based on reviews and practical experience of using

Pros:

• removes dizziness, tinnitus, in most cases improves hearing;
• preparation is cheaper than most of its analogues.

Cons:

• very long reception;
• is a disorder of the stool, a painful reaction of the intestine.

Prices in rubles

The average price for Tagist tablets is in the range of 76 rubles for 30 pcs.( 8 mg) to 138 rubles for 30 pcs.(24 mg).

Conditions and periods of storage

The medicinal preparation is listed in list B. Keep the drug preferably in a dry place, away from light and temperature not more than 24-26 degrees. Shelf life is 3 years.

Leave at the drugstore

Drug is dispensed by prescription

Analogues of Tagist drug

There are drugs that can replace the drug.

Vestibo

The therapeutic effect of betahistine dihydrochloride, the drug is produced in the forms of -8, -16 and -24 mg of the basic substance, each tablet on one side is labeled according to its quantity. Identical to natural synthetic histamine.

Vestibo helps to eliminate violations of from the cochlear and vestibular;reduces tinnitus, frequency and intensity of dizziness, improves hearing.

The drug is administered according to the prescription of the treating physician and according to the same scheme as Tagist.

Indications for use in treatment and restrictions on use are the same. The duration of admission is just as long. The price of the medicine varies from 124 rubles for 30 pcs.(8 mg) to 369 rubles for 30 pcs.(24mg) .The manufacturer is Germany.

Betaserk

The main active ingredient is betahistine dihydrochloride. Synthetic copy of histamine natural. It is prescribed with - Meniere's disease, atherosclerosis of cerebral vessels, disturbances in the vestibular apparatus, noise in the ears, hearing loss and so on. Betaserc is the original drug.

The release of the drug is standard - tablets of 8, 16 and 24 mg of the main active substance.

The scheme of taking the drug is equal to the scheme of receiving Tagist and Vestibo funds. Contraindications - the period of pregnancy and feeding, age to 18 years, intolerance of components, pheochromocytoma. The average daily dose of Betaserka for an adult is 24-48 mg of the drug.

One case of an overdose was fixed - taking the drug more than 600 mg once resulted in abdominal pain, drowsiness and nausea. Symptoms passed without medical intervention. The drug intake is stretched in time.

The cost of the drug - from 367 rubles.for 30 pcs.(8 mg) to 1350 rubles.for 30 pcs.(24 mg) of .Country of origin - France.

Asniton

The main active ingredient is also betahistine. Derivative analog of histamine.

A predisposition to taking is characteristic of the disease of the vestibular apparatus( tinnitus and dizziness), edema of the labyrinth of the inner ear, Ménière's disease and so on. The form of the preparation is -8 and -16 mg, tablets.

The preparation is administered according to the prescriptions of the attending physician according to a scheme similar to that of Tagist. The mechanism of action of the drug, restriction in the use and adventitious actions are similar to those of the above drugs.

The price of the medicine varies from 178 rubles.for 30 pcs.(8 mg) to 272 rubles.for 30 pcs.(16 mg) of .Shelf life of the drug is 24 months. The drug is manufactured in Russia.

According to all of the above, Tagest's analogues basically differ in price and country of origin. The effect of drugs on the body is purely individual, so it is selected by the attending physician.