At the present time, depressive disorders are increasingly observed in modern society. One of the effective means to combat depression of various genesis. Citalopram is an antidepressant, which is a selective inhibitor of serotonin reuptake.
The drug is available in tablet form. Tablets are white and biconvex.
In one package 14 tablets are packaged in doses of 40 or 20 mg. In a pack of cardboard, two blisters are placed. Also, the drug is produced by ten tablets in a blister pack.
Contents
- Formulation
- Pharmacological profile
- Scope and contraindications
- In what dosage and how to take medicine
- Signs of overdose and the effects of
- Adverse reactions
- Special instructions
- Interaction with other medicines
- Special patients
- Practical experience with
- Purchase and analogues
Composition of the preparation
In one tablet - 40, 20 or 10 milligrams of the active ingredient - citalopram hydrobromide. 
The auxiliary ingredients included in the drug include:
- magnesium stearate;
- Copovidone;
- microcrystalline cellulose;
- lactose monohydrate;
- corn starch;
- Croscarmellose sodium.
For the shell used:
- macrogol;
- hypromellose;
- titanium dioxide.
Pharmacological profile
The active substance acts on the synapses of neurons of the central nervous system, namely the selective blockade of the capture of the hormone serotonin.
The medicament acts on the human body as follows:
- eliminates fear and anxiety;
- helps to reduce psycho-emotional overstrain;
- improves mood;
- removes dysphoria;
- eliminates panic attacks;
- eliminates obsessive thoughts.
Therapeutic effect is observed about a week after the start of therapy.
The greatest amount of the active ingredient is accumulated approximately four hours after the drug is consumed. It binds to plasma proteins up to eighty percent. Changes in the indices of the active substance in the blood are linear.
Partially excreted when urinating and defecating after a day and a half.
Scope and contraindications
Indications for the appointment of citalopram tablets are the following neurological and psychological abnormalities and diseases:
- depression of various origins;
- anxiety-depressive disorder;
- obsessive-compulsive disorder;
- panic disorder;
- anorexia nervosa;
- Bulimia nervosa;
- affective disorder;
- panic attacks;
- various phobias;
- Somatic Disorder.
Assign Citalopram for depression in women after childbirth, with menopause and pregnancy. Also, tablets are recommended for alcoholism, which is accompanied by a depressed state.
Drug administration is possible if a phobic anxiety disorder is observed in elderly patients.
The main limitation for prescribing the drug is the increased sensitivity to the components of the medication in the patient.
Also limiting to the use of the drug are the patient's taking of MAO inhibitors and serotonin syndrome.
In what dosage and how to take medicine
Use tablets once a day for one piece, washed down with water.
First start with a minimum dosage, gradually increasing it under medical supervision. It is important to remember that the dosage is determined by an experienced doctor who takes into account the tolerability of the medicine, as well as the individual characteristics of the organism.
Symptoms of overdose and the effects of
Symptoms of overdose with citalopram are:
- drowsiness;
- status epilepticus;
- appearance of seizures;
- arrhythmia;
- nausea;
- vomiting;
- Perspiration;
- cyanosis of the skin.
A severe complication of an overdose is considered a confluence in a coma.
If such signs have appeared, then you should wash your stomach and take sorbents and laxatives. With convulsions, Diazepam is prescribed.
Adverse Reactions
Adverse reactions from taking citalopram tablets are rare. In practice, there are no cases when patients treated such complaints.
But theoretically, when using the drug, the heart rate may decrease, so taking the tablets provokes a bradycardia.
In addition, the instructions indicate that the following side effects on various body systems may occur:
- nervous system : sleep disorders, migraine, apathy, asthenia, panic, hallucinations, dizziness, confusion, mania, psychosis, loss of performance, convulsions, amnesia, tremor;
- digestive system : diarrhea, flatulence, vomiting, nausea, indigestion, dryness in the oral cavity, pain in the eryrdastral area, constipation, anorexia;
- respiratory system : sinusitis, dyspnea, coughing;
- sensory organs : impairment of taste, sight, hearing;
- cardiovascular system : hypotension orthostatic, pressure jumps, increased heart rate, arrhythmia;
- genitourinary system : frequency of urination, polyuria, menstrual irregularity, anorgasmia, impotence.
Fatigue, fever, itching and rash on the skin, joint and muscle pain, allergic reaction, fainting can also occur.
Usually, such effects are very rarely known about themselves, in the case of a significant excess of the dose and with prolonged use.
Special instructions
Patients in a depressed state, whose work is associated with increased attention, should abandon actions requiring rapid reaction.
The medicine for depression is not compatible with alcohol, so when it is used, it is necessary to exclude drinking alcohol.
If the patient has a history of kidney failure, then there is no need to adjust the dosage of the drug.
For violations of liver function, tablets should be consumed in minimum doses.
Interaction with other medications
When concurrent use of citalopram with psychotropic drugs usually reduces concentration.
It is forbidden to use tablets together with the use of blocking agents MAO, and also within fourteen days after their admission. Their simultaneous application can cause a hypertensive crisis.
Co-administration with serotonergic drugs enhances the effect of drugs.
Special patients
When breastfeeding and bearing a child, you can use Citalopram. However, it is used with caution and only under the supervision of a specialist.
The drug is not allowed to drink to children who have not reached the age of eighteen.
Practical experience of using
Reviews of doctors and opinion of patients who took or are taking Citalopram.
The use of citalopram and its medications is considered an effective way of getting rid of depression. However, in some cases, taking tablets may have a side effect on various organs and their systems.
That's why, first take a small dose of medicine, gradually increasing it. The active component of the tablets positively affects the production of serotonin, which helps to reduce the symptoms of mental disorders.
Taras Pavlovich, neurologist
A climax has just begun, which, in addition to all the other symptoms, provoked my depression. In the hospital, I was assigned Citalopram. For the second week I have been drinking the drug.
I want to note that it is really very effective, as the mood improved, apathy, nervousness and irritability passed. There were no adverse reactions from taking the tablets.
Natalia Ivanovna, 50 years old
My daughter prescribed a medicine after the birth of the child, as well as against a background of divorce, a depressed state developed. The doctor prescribed a prescription for Citalopram. Daughter he helped quickly - she again began to enjoy life and believed in their strength. But the tablets are not very cheap.
Olga Stanislavovna, 43,
So, in order to feel the therapeutic effect, but at the same time avoid cases of overdose and side effects, it is necessary to adhere to all medical prescriptions regarding dosages and the course of taking medication.
Advantages of the drug - efficacy, accessibility, rapidity of exposure and minimal list of contraindications.
Among the shortcomings can be identified relatively high cost and the possibility of side effects.
Purchase and analogues
Citalopram in a dosage of 10 mg costs from 170 rubles, at a concentration of active substance in the amount of 20 mg the price of the medicine starts from 400 rubles.
The medicine can be stored for three years in a dark place inaccessible to children. The optimum storage temperature is not more than twenty-five degrees. It is released in pharmacies only on prescription.
Replace Citalopram with preparations that have similar constituents or have the same effect on the body, such medicines include:
- Cytolone;
- Pram;
- Citaloline;
- Citol;
- Sedopram;
- Tsitalek;
- Umorap;
- Oprah;
- Cipramyl;
- Siozam.
