In case of circulatory disorders, many neuralgic diseases, insufficient nutrition of tissues and malfunctions in the metabolism, stimulant preparations are prescribed. The most popular is Actovegin.
Produced Actovegin in the form of small capsules of round shape and with a characteristic reflection, which are covered with a protective shell of yellow-green color.
The preparation includes:
- deproteinized hemoderivate - an active substance;
- magnesium stearate;
- talc;
- Povidone;
- cellulose.
Contents
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- Contents
- What's best- Pills or injections?
- Price
- Contents
First introduction to the drug
Tablets Actovegin - an antihypoxant, is a hemoderivat, which is obtained by dialysis and ultrafiltration( compounds with molecular weight less than 5000 Daltons penetrate).
The drug increases the utilization of glucose by cells, increases oxygen consumption, increases oxidative phosphorylation in the mitochondria, thereby increasing the level of ATP and normalizing the metabolism of cells and the balance of energy in tissues.
The drug increases the concentrations of ATP, ADP, phosphocreatine, as well as amino acids( glutamate, aspartate) and GABA.The effect of the drug on the absorption and utilization of oxygen, as well as insulin-like activity with the stimulation of transport and glucose oxidation, are significant in the treatment of diabetic polyneuropathy.
In patients with diabetes and diabetic polyneuropathy, Actovegin reliably reduces the symptoms of the latter( stitching pain, burning sensation, paresthesia, numbness of the lower limbs).Objective disorders are reduced sensitivity, mental well-being of patients improves.
All of the above properties of the drug make it possible to actively fight not only with diabetes and metabolic disorders, but also with complex neuralgic diseases that could be caused on nervous or other soil.
Pharmacological profile
Pharmacological action of the drug is that it is able to penetrate deep into the 
cells of tissues at the most complex molecular level and thus the drug promotes the accelerated absorption of glucose, vitamins, trace elements and other minerals, which, in turn, leads tostimulation of the whole body.
In the treatment of neuralgic disorders, it is the absorption of vitamins and essential trace elements that can stimulate brain activity.
Due to the fact that the composition of the drug includes various physiological supplements, it is not possible to fully study its pharmacological action.
As already mentioned, due to the fact that the composition of the drug includes physiological supplements to fully study its effect on the body, it is not possible.
For the same reason, there is no exact data on exactly how all elements of the drug are absorbed, absorbed and removed from the body. But, given that all the physiological components of the drug are derivatives of the human body, then after Actovegin began to act, it is excreted in 3-4 hours together with sweat or urine.
Once the tablets have been taken orally, they begin to be actively absorbed by the cells of the body, due to which the rather fast healing effect is determined. Then, the residual derivatives enter the circulatory system and after a time are removed together with urine and sweat.
Evidence-Based Medicine
On the Internet, you can find a lot of articles about the fact that in fact, the action of Actovegin does not have any valid basis, and therefore its use can be considered useless.
But, such statements, as a rule, are unreasonable, as this drug is actively used by doctors and is on the pharmaceutical market for a long time.
Similar rumors and assumptions are based on the already mentioned above physiological components of the drug, because of which it is problematic to fully study the effect of the drug on the body. But, whether these assumptions are true, it is necessary to understand.
Over the past few years, many scientific and practical experiments have been conducted to study the action of Actovegin and most of them have been successful, because according to the latest statistics, a number of drug effects were justified from a medical and scientific point of view.
According to the latest received data, Actovegin represents a variety of non-standard options for the treatment of various diseases, including neurological disorders.
As is known to date, the drug is already actively used in complex therapy for the treatment of neuralgic, mental and psychological disorders. In addition, the drug can successfully deal with other equally serious diseases( for example, such as diabetes mellitus).
So, the assumption that Actovegin does not have the proper effect on the body is just a medical myth that was created by ignorant people and in fact the effectiveness of the drug has already been substantiated by evidence-based medicine.
Scope of application
Why practicing physicians prescribe to take Actovegin: 
- is recommended for complex therapy during treatment of metabolic and nutritional disorders of the body cells;
- vascular diseases of the brain;
- for disorders in the circulation of the brain;
- for the prevention of dementia;
- neuralgic disorders caused by nervous stress;
- arterial and venous disorders in the operation of blood vessels, which can lead to varicose veins;
- diabetes and pre-diabetic condition.
The drug has no contraindications, and it is not recommended for use only if the patient has an individual intolerance to the drug that was caused by an allergic reaction.
Instructions for Use
The drug should be taken half an hour before meals or 2 hours after that. The tablet should be washed with water or milk, there is no need to chew it. The recommended dosage of the drug is 1-2 tablets per day. The course of treatment is a month and a half.
At the beginning of the course of treatment, the recommended dosage of the drug is 2 grams per day, gradually this figure increases to 5 grams.
Overdose and side effects of
If the recommended level of the drug has been exceeded, this does not threaten the patient, since no cases of overdose have been reported to date.
Of the side effects should be identified only possible allergic reaction. It should be remembered that with its manifestation, the course of treatment with Actovegin should be gradually stopped.
Special instructions
According to clinical studies that have been conducted by the manufacturer, the drug and alcohol are incompatible.
If the patient has irregularities in the function of the kidneys or liver, then taking the drug is not recommended. Actovegin is often used in complex treatment together with other stimulant drugs.
When pregnancy and lactation, take Actovegin tablets is not worth it, or do it under constant medical supervision.
Children are prescribed a drug only after 5 years.
Practical experience of doctors and patients
Reviews of patients and the review of our expert, a neurologist at Actovegin.
Physician's review
The review of this drug starts with the fact that the drug is deproteinized hemoderate of the blood of calves. This means that the blood serum of these animals is used as a raw material for the production of Actovegin, subjecting it to ultrafiltration and dialysis, that is, thorough purification.
Despite the fact that the preparation is exclusively an animal, of "natural" origin, there are quite a lot of disputes about its effect on the human body as a whole. Some patients who took Actovegin with neuralgic disorders leave very good reviews about the drug, note the rapid healing effect and improvement of the condition.
However, there is a significant percentage of patients who report such a side effect of drug treatment as an allergic reaction and a deterioration in well-being. In this case, the patients themselves experienced discomfort in the stomach, nausea, weakness during the course of treatment. The listed symptomatology, as a rule, left with the termination or ending of reception of a medicine.
Oleg Yakovlev, 42, neurologist
The opinion of ordinary people
Because of a nervous breakdown, I started neuralgic anorexia, which was accompanied by a metabolic disorder. Since this disease was caused by a nervous breakdown, the doctor prescribed me Actovegin, which, according to him, stimulates the body, restores metabolism and absorbs cells of the body.
After completing the course of treatment, I began to feel much better. For today I continue treatment and have almost got rid of the illness!
Alina Nikitenko, 25 years old
With neuralgic disorders, the drug can be called simply salvage. Because of the monotonous work that fell down, I felt very shattered, which eventually developed into a depression. Without thinking twice, I turned to a specialist for help, and he appointed Actovegin to me. The drug I have been using for 2 weeks and my condition is gradually improving.
Nikita Mikhalkov, 30 years old
Advice on receiving patients from
Before starting treatment, it should be noted that one of the main features of Actovegin is that it can delay the withdrawal of water from the body for a short time 
, which is contraindicated for diabetics. Therefore, the medicine should be taken according to the instructions and under the constant supervision of the attending physician.
Advantages of the medicine:
- medication is prescribed for a wide range of diseases;
- natural composition;
- a small number of side effects;
- high efficiency.
Disadvantages:
- cost;
- available small, but still side effects, such as, a possible allergic reaction and water retention in the body.
Which is better - pills or injections?
Reply to the question what is better than pills or nyxes Avtovine in one or another situation directly depends on the disease and on the type of treatment that was chosen by the doctor.
For example, with nervous disorders it is recommended to take pills, since they have a cumulative effect, and in diabetes mellitus, preference should be given to injections, since the active substance, thus, gets faster into the body.
Price issue
The price of tablets Avtovine in pharmacies does not exceed 2000 rubles. The medicine is stored for 3 months in a dark place.
The preparation is dispensed only by prescription.
