Multiple sclerosis affects many people around the world. Statistics say that today the number of MS patients has reached 2 million.
Therefore, modern medicine develops effective drugs to treat this disorder. One of the best remedies is the Cinnovex drug.
This medication helps to normalize the nervous system and slows the course of multiple sclerosis.
Contents
- Form release and component parts
- Pharmacological profile
- Indications and contraindications for use
- Therapy and dosage regimen
- The period of bearing and breastfeeding
- Side effects
- Special instructions
- From the practical experience of using
- Purchase of the drug and its analogues
Form of leaveand components of
The Synnovex medication is manufactured as a lyophilizate for solution preparation. The solution is used for intramuscular or intravenous administration.
The structure of the lyophilizate is white or almost white in color. Additionally, it is completed with a solvent, which is available as a clear liquid with a colorless structure.
The lyophilizate is placed in 3 ml glass vials, additionally, an ampoule with a solvent liquid with a volume of 1 ml and a disposable syringe with two needles are supplied. All placed in trays of plastic material of 4 pieces. In the kit are 8 alcoholic wipes. Everything is packed in a cardboard box.
The preparation contains the following components:
- the main active element is interferon beta-1a;
- auxiliary constituent elements - human albumin, sodium hydrogen phosphate, sodium dihydrogen phosphate, sodium chloride;
- constituent elements of the solvent - water for injection.
Pharmacological profile
Synovex refers to recombined interferons beta-1.This agent has immunomodulatory, antiviral and antiproliferative properties.
Biological features of the drug consist in its binding to receptors of a specific type on the surface of the cells of the human 
organism and the launch of a complex cascade of intercellular influences.
All this results in interferon-mediated expression of numerous gene products and markers. After the administration of the drug, the level of these components in the serum can be increased within 4-7 days.
The principle of drug exposure has not yet been fully understood. It is known that interferon provides a limitation of the damage to the central nervous system, which underlies the development of multiple sclerosis.
The pharmacokinetics of interferon beta-1a depend on the antiviral state of the substance. During use, the highest levels of antiviral activity in the plasma structure can be achieved from 5 to 15 hours. The half-life can be almost 10 hours. The level of bioavailability can be about 40%.
Indications and contraindications for use
Synovex should be used with the following indications:
- During recurrent multiple or multiple sclerosis .In this case, the drug is prescribed if during the
of this disorder there are at least two relapses during the previous three-year period, provided that there is no symptomatic of disease progression between relapses. The use of the drug provides a slowdown in the progression of the disease and increases the time interval between relapses for a period of more than two years. - is used during therapy in patients who have demyelination of with increased inflammation along with intravenous administration of corticosteroids.
The instructions for the Cynnovex medication state the following conditions in which the use of the drug is contraindicated:
- when carrying a child;
- during breastfeeding;
- is not recommended for patients with epileptic seizures;
- during pronounced depressive states;
- during severe depression, which is accompanied by thoughts of a suicidal nature;
- is not recommended for children under 12 years of age;
- in the presence of hypersensitivity to constituent components.
Therapy and Dosage Scheme
It is recommended that the use of the Cynnovex medication be initiated under the supervision of a physician who has experience in the treatment of MS.
The recommended dosage of medication for adults during RRS therapy may be about 30 μg or 6 million IU, which is 1 ml of solution. This dosage should be administered once every 7 days using the intramuscular route.
Treatment therapy usually begins with a full or half-dose. The drug is given in this dose once every 7 days. After that, the dosage can be increased to 30 mcg so that the body can quickly get used to the drug.
To achieve sufficient effectiveness after the start of therapy, the dosage gradually increases to 30 mcg once a week. In the following period, you must adhere to this dosage.
Breastfeeding and Breastfeeding Period
Due to the fact that serious side effects may occur during the period of bearing the child, it is not recommended to use it during this period. There have been cases when using medication during pregnancy, spontaneous abortions have occurred.
At the time of use by women with reproductive capacity, it is recommended to use effective contraceptives.
Ingredients of the medicine are included in the composition of breast milk, therefore, during the period of breastfeeding, the use of Sinnoweks is contraindicated.
Side effects of
During the use of the Cynnoveks medication, there may appear side effects in the form of:
- flu-like symptoms of - the onset of headache, fevers, chills, muscular and
joint pain; - digestive tract disorder - upset of stool, nausea, decreased appetite, vomiting;
- disorders of the nervous system - sleep problems, dizziness, nervousness, sometimes there are depression, thoughts with suicidal tendencies, split personality, convulsions;
- cardiac and vascular disruption - increased heart rate, heart rhythm disturbances;
- allergic reactions - the appearance of redness of the skin, swelling, swelling, pain at the injection site;the appearance of skin rashes, itching, hives.
Special instructions
When using a medicine, the following important nuances should be considered.
Patients who have depressive conditions, the drug should be administered with extreme caution. If suddenly there are symptoms of depression and suicidal thoughts, then immediately you need to inform the doctor about it.
Used with caution in patients with a history of seizures. In cases where patients have seizures, which before they did not appear, it is worth to cancel the use of medication, consult a doctor and conduct the necessary treatment.
It is prescribed with extreme caution also to those patients who have renal and hepatic insufficiency. In these cases, the medication is used under the supervision of a specialist.
From the practical experience of using
A review of the doctor and patient reviews of the Sinnovex preparation.
Synnovex is an interferon that has an immunomodulatory, antiviral, antiproliferative effect. This medication is prescribed during the therapy of multiple sclerosis.
Its use makes it possible to slow the course of the disease, and also eliminates negative symptoms. Use of the drug increases the time between seizures by several years. In general, the remedy is well tolerated, but it is better to have a preliminary examination and consult a doctor.
The doctor neurologist
Multiple sclerosis at me since a birth. This frustration gives me a lot of problems, but I learned to live with this ailment, while I lead a full life.
Over the entire period I was prescribed various drugs to support the general condition. Over the past 5 years I have been using the drug Synnovex, it made my condition much easier. Symptoms of MS almost does not bother me, except for this relapse does not appear for 2-4 years.
Alena, 36 years old
Mom is 75 years old, she has about 20 years of PC.What are the only drugs that they did not assign to her, but not one of them did not have the desired effect. Well we got an experienced doctor who prescribed to use the Cynnovex tool.
Of course, at first there were side effects in the form of headaches, chills, fever. But in due course all has passed. The main thing at it or her does not arise relapses 3 years.
Marina, 52 years old
Purchase of the drug and its analogues
Treatment of multiple sclerosis has always been a matter of expensive and complex. 
No exception, and this drug, so the packaging price of the drug Synnoveks at the end of 2016 is from 11 thousand to 13 thousand rubles, are also available for the purchase of its analogs:
- Avonex;
- Genfaxon;
- Rebif;
- Interferon beta-1a.
